...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 8093413 | Method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optical processing to betulin The invention relates to a method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin, wherein the birch bark is ground, mixed with two- to twenty-fold excess volume of water and is stirred so tha... | 01/10/2012 |
| 7851641 | Compounds useful for treating neurodegenerative disorders As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method compr... | 12/14/2010 |
| 7410958 | Triterpene quaternary salts as biologically active surfactants The invention provides novel compounds that are quaternary amine derivatives of betulin and other triterpenes. The compounds have antibacterial, antifungal, and surfactant properties. ... | 08/12/2008 |
| 7381717 | Anti-HIV agents with dual sites of action The present invention provides compounds of the general structure: which are substituted at the 3 and 28 positions, along with pharmaceutical formulations containing the same and methods of treating viral infections employi... | 06/03/2008 |
| 7312205 | Methods and compositions for inhibiting tumor growth The present invention relates to novel betulinic acid derivatives with increased activity for the treatment of carcinomas and HIV diseases, a method for preparing such novel betulinic acid derivatives as well as their use as pharmaceuticals. ... | 12/25/2007 |
| RE39862 | Unsaturated 14, 15-cyclopropanoandrostanes, a method for their production and pharmaceutical compositions containing these compounds The invention relates to new unsaturated 14,15-cyclopropano-androstanes of the general formula (I) to their synthesis and to pharmaceutical compositions, containing these compounds. The compounds of formula (I) have gesta... | 09/25/2007 |
| 7232574 | Long chain alcohols provided in edible oils The present invention provides a method for incorporating long chain alcohols into edible oils. The long chain alcohol/edible oil admixture is then suitable for use in preparation of various foods. The long chain alcohol is added by the introduction of energy and in... | 06/19/2007 |
| 7199114 | Triterpene quaternary salts as biologically active surfactants The invention provides novel compounds that are quaternary amine derivatives of betulin and other triterpenes. The compounds have antibacterial, antifungal, and surfactant properties. ... | 04/03/2007 |
| 7191438 | Computer functional architecture and a locked down environment in a client-server architecture A method, an apparatus and a computer program product are disclosed for providing a lockeddown client environment in a client-server architecture of a computer network. In the method, an asset database is checked via the computer network to validate settings for con... | 03/13/2007 |
| 7091195 | Method of preparing and use of prodrugs of betulinic acid derivatives A composition and method of preventing or inhibiting tumor growth and, more particularly, of treating a malignant tumor, using prodrugs of plant-derived compounds and derivatives is disclosed. In the method, a composition containing betulinic acid or a betulinic aci... | 08/15/2006 |
| 7053228 | Sulfur analogues of 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) for treating excess of glucocorticoids The present invention is related to novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues, their use as antiglucocorticoids for the treatment and/or prophylaxis of disease associated to an excess of glucocorticoids. In particular, the invention relates to the... | 05/30/2006 |
| 7026305 | Anti-HIV agents with dual sites of action The present invention provides compounds of the general structure: which are substituted at the 3 and 28 positions, along with pharmaceutical formulations containing the same and methods of treating viral infections emp... | 04/11/2006 |
| 6951847 | Methods of treating fungal infections using lupeol The invention is directed to methods of treating fungal and yeast infections using lupeol or solvates, hydrates, or clathrates thereof. The method also encompasses methods of treating fungal and yeast infections by administering to a mammal in need of such treatment... | 10/04/2005 |
| 6943260 | Process for obtaining betulinic acid The invention relates to an improved process for obtaining highly pure, crystalline betulinic acid from a methanolic extract of ground plane tree cortex and/or plane tree bark, as well as highly pure crystalline betulinic acid which is solvated with one equivalent o... | 09/13/2005 |
| 6723715 | 14, 15-cyclopropanosteroids of the 19-norandrostane series, method for producing said compounds and pharmaceutical preparation containing said compounds The invention relates to the new 14,15-cyclopropanoandrosteroids of the 19-norandrostane series of the general formula (I) their synthesis and to pharmaceutical compositions containing these compounds. The compoun... | 04/20/2004 |
| 6710039 | Unsaturated 14,15-cyclopropane-androstanes, a method for their production and pharamceutical compositions containing these compounds The invention relates to new unsaturated 14,15-cyclopropano-androstanes of the general formula (I) to their synthesis and to pharmaceutical compositions, containing these compounds. The compounds of formula (I) ha... | 03/23/2004 |
| 6706700 | 14β,15β-methylene-17α-hydroxymethyl-androgens The disclosed invention relates to the unexpected finding of novel steroids which are characterized by a 14β,15β-cyclopropane ring and a 17α hydroxymethyl group. These steroids according to the invention are found to have in common an androgenic activity. They ca... | 03/16/2004 |
| 6670345 | Betulinic acid derivatives for inhabiting cancer growth and process for the manufacture of betulinic acid The invention relates to the use of betulinic acid derivatives for the inhibition and or prevention of cancer growth. The invention also relates to novel betulinic acid derivatives useful for inhibition of tumor cancer cells and a process for the preparat... | 12/30/2003 |
| 6642217 | Triterpenes having human antifungal and antiyeast activity Methods of treating a fungal or yeast infection and of killing or inhibiting fungi or yeast are disclosed. The methods use derivatives of triterpenes that are abundant in birch bark and other plants. The triterpenes include betulin, allobetulin, and lupeo... | 11/04/2003 |
| 6596713 | Steroid esters and amides, process for their production and their pharmaceutical use New steroids and amides of formula I ##STR1## are described, in which the variables are defined by the description. Relative to the basic hydroxy compounds ("initial compounds"), the new compounds are distinguished by a considerably improved solubility an... | 07/22/2003 |
| 6583130 | C13-substituted estra-1,3,5,(10)-trien-3-yl sulfamates, methods of preparing same, and pharmaceutical compositions containing these compounds The invention relates to new C13 -substituted estra-1,3,5(10)-trien-3-yl sulfamates of general formula I, ##STR1## wherein R1 represents an acyl residue, oxycarbonyl residue, aminocarbonyl residue, sulfonyl residue, or aminosulfonyl ... | 06/24/2003 |
| 6569842 | Method of preparing and use of prodrugs of betulinic acid derivatives A composition and method of preventing or inhibiting tumor growth and, more particularly, of treating a malignant tumor, using prodrugs of plant-derived compounds and derivatives is disclosed. In the method, a composition containing betulinic acid or a be... | 05/27/2003 |
| 6503895 | Antigestagenically active steroids with a fluorinated 17-alkyl chain This invention describes the new 17댟luoroalkyl steroids of general formula I ##STR1## as well as their physiologically compatible salts with bases. The new compounds have an extraordinary strong antigestagenic action and are suitable for the produc... | 01/07/2003 |
| 6432939 | 17a-hydroxy-4-androstene-3-one and derivatives thereof This invention describes 17-hydroxy-4-androstene-3-one and its derivatives of the general formula I ##STR1## a method for producing these compounds and pharmaceuticals containing these compounds. The compounds according to the invention can be used... | 08/13/2002 |
| 6403816 | Betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis The invention relates to novel betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis.... | 06/11/2002 |
| 6335441 | 5ଲ-cyano-substituted steroid compounds Novel 5ଲ-cyano steroid compounds including compounds of Formula VII: ##STR1## wherein A--A, B--B, R3, R8 and R9 are as defined in the specification.... | 01/01/2002 |
| 6316432 | Antigestagenically active steroids with a flourinated 17 -alkyl chain This invention describes the new 17-fluoroalkyl steroids of general formula I ##STR1## as well as their physiologically compatible salts with acids, and for --CO2 R9 radicals with R9 meaning hydrogen as well as thei... | 11/13/2001 |
| 6258946 | Keto-Substituted Steroid Compounds Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone, useful as a diuretic, and other compounds of Formula I ##STR1## wherein the variables are as defined by the specification.... | 07/10/2001 |
| 6229029 | 11ଲ-aryl substituted 14,17-ethanoestratriens, method for the production of these compounds and their use in the production of medicaments This invention describes 11ଲ-aryl-substituted 14,17-ethanoestratrienes of general formula (I). The new compounds are selective estrogens whose action occurs in a tissue-selective manner. The estrogenic action occurs in particular on bone, in the car... | 05/08/2001 |
| 6214814 | Use of betulinic acid derivatives for inhibiting cancer growth The invention relates to the use of betulinic acid and its derivatives for the inhibition and/or prevention or cancer growth. The invention also relates to novel betulinic acid derivatives useful for the inhibition of tumor/cancer cells and a process for ... | 04/10/2001 |
| 6180803 | 19-nor-pregnene derivatives and pharmaceuticals containing such derivatives The invention relates to compounds of the formula: ##STR1## in which R1, R2, R3, R4, R5, R6, n and X are as defined in the specification, and to pharmaceutical compositions containing them.... | 01/30/2001 |
| 6177418 | Tetracyclic triterpenes as cholesterol-lowering and anti-atherosclerosis agents The invention is directed to compounds, compositions and method of preparation of compounds of formulae I and II: ##STR1## wherein X, Q1, Q2, R1 and R2 are as defined by the specification. The compounds are disc... | 01/23/2001 |
| 6096732 | Steroid esters, process for their production and their pharmaceutical use Steroid esters of formula I ##STR1## are described, wherein m, n and x are as defined by the specification. The compounds are distinguished from the basic hydroxy compounds by considerably improved solubility as well by increased biological activity ... | 08/01/2000 |
| 6080735 | Estra-1,3,5(10)-trien derivatives, processes for their preparation and pharmaceutical compositions containing these compounds This invention is relating to new estra-1,3,5(10)-trien-sulfamates carrying at the 3-position an R--SO2 --O--group, with R being an R1 R2 N--group in which R1 and R2, independently of each other, repr... | 06/27/2000 |
| 6071898 | Asiatic acid derivatives having modified A-ring Asiatic acid derivatives having a modified A-ring, as represented by formula 1 are disclosed. ##STR1## Pharmaceutical compositions and methods of treating cancer and hepatotoxicity utilizing compounds of formula 1 are also disclosed.... | 06/06/2000 |
| 6048847 | Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this The invention relates to use of betulinic acid and/or its derivatives for treating, inhibiting, and/or preventing tumors or cancer growth more particularly, to treating leukemia, lymphomas, lung, prostate and ovarian cancer. This invention also relates to... | 04/11/2000 |
| 5986115 | 7-(.xi.-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7-(.xi.-aminoalkyl)-estratrienes as well as their use for the production of pharmaceutical agents This invention describes new, substituted 7-(.xi.-aminoalkyl)-estratrienes of general formula I ##STR1## in which side chain SK is a radical of partial formula ##STR2## as well as their physiologically compatible addition salts with organ... | 11/16/1999 |
| 5973172 | 14-,17--C2 -bridged norprogesterone derivatives The invention describes 14,17-C2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are in contrast, with the disclaimed compound, the new com... | 10/26/1999 |
| 5874598 | Process for producing 1,2,3-trioxysteroid derivatives A process for the production of a compound of formula (II), which comprises reacting an epoxy compound of formula (I) with an alcohol, wherein the reaction is carried out under a basic condition. ##STR1## R1, R2, R3, ... | 02/23/1999 |
| 5869708 | Process for the isolation of oryzanols from crude dark acid oil (rice bran) A process for the isolation of oryzanols from crude dark acid oil (rice bran) which comprises (a) distilling the free fatty acids from crude dark acid oil by conventional methods, (b) hydrolyzing the resultant residue by conventional methods, (c) dissolvi... | 02/09/1999 |