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| Number | Title | Issue Date |
| 7495115 | Steroid conjugates, preparation thereof and the use thereof Conjugates comprising one or more steroids conjugated with one or more mammalian proteins are disclosed. The conjugates are useful for diagnosis or treatment of solid cancer and haematological malignancies. Further the conjugates exhibits a synergistic action togeth... | 02/24/2009 |
| 7358379 | Steroid conjugates, preparation thereof and the use thereof Conjugates comprising one or more steroids conjugated with one or more mammalian proteins are disclosed. The conjugates are useful for diagnosis or treatment of solid cancer and hematological malignancies. Further the conjugates exhibit a synergistic action together... | 04/15/2008 |
| 6969708 | Process for the preparation of a high purity composition comprising (7α, 17α)- 17-hydroxy- 7-methyl- 19-nor-17-pregn-5(10)-en-20-yn-3-one The invention pertains to a process for the preparation of a high purity composition of (7α, 17α)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one. The process provides for a composition with less than 0.5% of (7α, 17α)-17-hydroxy-7-methyl-19-nor-17-preg... | 11/29/2005 |
| 6890533 | Betulinol derivatives The present invention is directed to betulinol derivatives and betulinol-antibody conjugates having the formulae: and HO-antibody-spacer-(A2)n and, in particular, betulinol dim... | 05/10/2005 |
| 6737417 | Compounds with hydroxycarbonyl-halogenoalkyl side chain The present invention provides a compound consisting of a moiety and a group chemically bonded to said moiety, wherein said moiety contains a compound having low activity following oral administration or its parent scaffold and said group has the following general f... | 05/18/2004 |
| 6534490 | Unsaturated 14, 15-cyclopropanoandrostanes, method for the production thereof and pharmaceutical preparations containing said compounds Described are new, unsaturated 14,15-cyclopropano-androstanes of general formula (I) and their pharmaceutically acceptable salts, a process for their production and pharmaceutical preparations that contain these compounds. The compounds are characterized ... | 03/18/2003 |
| 6521767 | Method for suspension hydrogenation of an anthraquinone compound in a special reactor in order to produce hydrogen peroxide In a process for the suspension hydrogenation of an anthraquinone compound or a mixture of two or more thereof in a reactor in which there are present the working solution in which at least one catalyst is suspended and, in addition, a hydrogen-containing... | 02/18/2003 |
| 6433199 | Quinone derivatives The invention relates to a quinone derivative of the following formula: ##STR1## which is capable of converting into two alkylating agents upon bioreduction. Substituents A, B, C, and D are as described herein.... | 08/13/2002 |
| 5998594 | Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use A chromogenic receptor comprises a self-assembled chromogenic compound having at least one intrinsic binding site. The chromogenic compound is characterized by the property of producing a reversible color change responsive to binding a target substrate to... | 12/07/1999 |
| 5977096 | Steroids with radical-attracting aromatic substituents, process for the production thereof and pharmaceutical compounds containing the said substances Novel substituted steroid compounds are disclosed which are more effective than known radical-trapping agents in methods of prophylaxis and therapy of radical-mediated cell damage and of treatment of diseases due to radical-mediated cell damage. The novel... | 11/02/1999 |
| 5516768 | Uncompetitive inhibition of steroid and 5-reductose Invented are compositions of competitive and uncompetitive inhibitors of steroid 5--reductase, pharmaceutical compositions containing the compositions of inhibitors and methods of using these compositions to inhibit steroid 5--reductase. Als... | 05/14/1996 |
| 5240814 | Curable, heat activatable transfer toners A non-electroscopic prolonged tack toner for transferring toned images to an image receptor at low temperatures with improved back transfer characteristics.... | 08/31/1993 |
| 4205004 | 25-Alkylcholest-5-ene-3ଲ,22-diols and esters thereof 25-Alkylcholest-5-ene-3ଲ,22-diols and esters thereof adapted to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase are disclosed.... | 05/27/1980 |
| 4092310 | Difluorosteroids and processes for their manufacture A novel group of 18,18-difluorosteroids of the general formula ##STR1## wherein St, R1 and R2 have the meanings given hereinafter is produced by a chemically novel process characterized in that a corresponding 18-oxo compound is... | 05/30/1978 |