Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 8093411 | Cyanine dyes and their applications as luminescence quenching compounds The quenching compounds of the invention are weakly luminescent cyanines that are substituted by one or more heteroaromatic quenching moieties. The quenching compounds of the invention exhibit little or no observable luminescence and efficiently quench a broad spect... | 01/10/2012 |
| 7982060 | Intermediates for the preparation of analogs of Halichondrin B The present invention provides macrocyclic compounds, synthesis of the same and intermediates thereto. Such compounds, and compositions thereof, are useful for treating or preventing proliferative disorders Formula (F-4). ... | 07/19/2011 |
| 7910753 | Cyanine dyes and their applications as luminescence quenching compounds The quenching compounds of the invention are weakly luminescent cyanines that are substituted by one or more heteroaromatic quenching moieties. The quenching compounds of the invention exhibit little or no observable luminescence and efficiently quench a broad spect... | 03/22/2011 |
| 7589219 | 2,5-bis-diamine-[1,4]benzoquinonic derivatives, useful for the treatment of alzheimer's disease, method for preparing them and intermediates of said method 2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described. ... | 09/15/2009 |
| 7365089 | Triazolo-quinolin derivatives useful as adenosine receptor ligands The present invention relates to adenosine A3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the gen... | 04/29/2008 |
| 7282519 | Nitrosated and nitrosylated diuretic compounds, compositions and methods of use The invention describes novel nitrosated and/or nitrosylated diuretic compounds or pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated diuretic compound, and, optionally, at least one nitric oxide ... | 10/16/2007 |
| 7276573 | Method for producing monoesters and diesters of polytetrahydrofuran and of tetrahydrofuran copolymers The present invention provides a process for preparing mono- or diesters of polytetrahydrofuran or of tetrahydrofuran copolymers by polymerizing tetrahydrofuran in the presence of at least one telogen and/or of a comonomer over an acidic catalyst, wherein the polyme... | 10/02/2007 |
| 7153884 | C-2′ methylated derivatives of paclitaxel for use as antitumour agents Taxane derivatives of formula (I) in which: R is trifluoromethyl, phenyl, 2-furyl, 2-thienyl; R1 is t-butoxycarbonyl or benzoyl; R2 is hydroxy; R3 is hydrogen or, together with R2, it forms the residue of a cyclic carbonat... | 12/26/2006 |
| 7128983 | Furan-containing hole transporting materials A furan-containing compound of formula (I): Ar is aryl, heteroaryl, or oligoaryl; A is furyl; B is aryl or heteroaryl; R1 is hydrogen, alkenyl, alkynyl, aryl, heteroaryl, cyclyl, heterocyclyl, or oligo... | 10/31/2006 |
| 7078542 | Nonlinear optical compounds and methods for their preparation Nonlinear optically active compounds, methods for making nonlinear optically active compounds, compounds useful for making nonlinear optically active compounds, methods for making compounds useful for making nonlinear optically active compounds, macrostructures that... | 07/18/2006 |
| 7018430 | Method of mass-coloring synthetic materials The present invention relates to a method of mass-coloring synthetic materials, which comprises using at least one pigment dye of formula (1) wherein R and R1 together form a phenyl or heteroaryl radical and R2 is hydrogen, or R1 and... | 03/28/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6972275 | Oil-in-oil emulsion lubricants for enhanced lubrication Novel oil-in-oil emulsions and methods of lubrication using the same are provided. The lubricants are stable emulsions of carrier fluid and high viscosity fluid that display superior properties related to lubricating film thickness and reduced shear strength. ... | 12/06/2005 |
| 6965041 | N-acylphosphoramidites and their use in oligonucleotide synthesis The present invention provides a compound of formula (I), (II), or (III), wherein R1, R2, R2′, R3, and R3′ are the same or different and each is H an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl, or ... | 11/15/2005 |
| 6933091 | Photoconductor for electrophotography and quinomethane compound A highly sensitive positively charged type electrophotographic photoconductor includes an organic compound that transports electrons efficiently, improving light emission efficiency. The photoconductor is used in an electrophotographic drum, an electrophotographic c... | 08/23/2005 |
| 6887737 | Epoxidized acetals and thioacetals, episulfidized acetals and thioacetals, and reworkable thermosetting resin compositions formulated therefrom This invention relates to epoxidized acetals and thioacetals, episulfidized acetals and thioacetals, thermosetting resin compositions based on such epoxidized acetals and thioacetals, episulfidized acetals and thioacetals, reaction products of which are controllably... | 05/03/2005 |
| 6878740 | Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine compounds Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine compounds, processes for their preparation, medicaments and pharmaceutical compositions containing them, and their use in treatment methods and in the preparation of analgesics, in the preparation ... | 04/12/2005 |
| 6869967 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in th... | 03/22/2005 |
| 6841571 | Compounds useful as reversible inhibitors of cysteine proteases Disclosed are cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R2, R3, R4, R6, R8 and Y are defined herein. The compounds are useful for treating autoimmune and othe... | 01/11/2005 |
| 6737440 | Synthesis and antimicrobial activity of novel dicationic “reversed amidines” The present invention relates to novel 2,5-bis {[alkyl(or aryl)imino]aminophenyl}furans and thiophenes of the general formula in which R1, R2, R3 and R4 are each independently ... | 05/18/2004 |
| 6716937 | Method for the single-step production of polytetrahydrofuran and tetrahydrofuran copolymers A process for the single-stage preparation of polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 650 to 5000 dalton by polymerization of tetrahydrofuran over a heterogeneous acid catalyst in the presence of at least one telo... | 04/06/2004 |
| 6706724 | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use The invention describes novel substituted aryl compounds that are cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfer... | 03/16/2004 |
| 6693201 | Fluorescent photochromic fulgides, particularly for optical memories Photochromic chemicals consisting essentially of colored fluorescent heterocyclic fulgides are particularly suitable for optical memories. The preferred heterocyclic photochromic fulgides consist essentially of colored 2-indolyfulgides capable of excitati... | 02/17/2004 |
| 6677341 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and m... | 01/13/2004 |
| 6620804 | Selenophene anti-tumor agents Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: ##STR1## wherein R1 and R2 are independently selected from the group consisting of; ##STR2## H, CHO, ... | 09/16/2003 |
| 6613787 | Compounds that exhibit specific molecular recognition of mixed nucleic acid sequences and bind in the DNA minor groove as a dimer Asymmetric derivatives of furamidines with one of the phenyl rings of furamidine replaced with a benzimidazole have been found by quantitative footprinting analyses to bind GC containing sites on DNA more strongly than to pure AT sequences. These compound... | 09/02/2003 |
| 6599648 | Heterarylbenzene compounds A method of preparing a compound of formula I is described. ##STR1## In this compound, each of R1 -R6 is, independently, ##STR2## in which Y is O, S, NH, or C(R7).dbd.C(R8). Each of R7 -R11... | 07/29/2003 |
| 6570023 | Process for preparing toluenesulfinates A process for preparing novel compounds useful in the preparation of 1H-indole-3-glyoxamides.... | 05/27/2003 |
| 6521660 | 3'-alkyl substituted taxanes and pharmaceutical compositions containing them Taxane derivatives having an alkyl substituted C13 side chain.... | 02/18/2003 |
| 6512122 | Hetarylbenzene compounds A method of preparing a compound of formula I is described. ##STR1## In this compound, each of R1 -R6 is, independently, ##STR2## in which Y is O, S, NH, or C(R7).dbd.C(R8). Each of R7 -R11... | 01/28/2003 |
| 6492416 | 4,5-diaryl-3(2H)-furanone derivatives as cyclooxygenase-2 inhibitors The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.... | 12/10/2002 |
| 6455711 | Method for producing polytetrahydrofuran A process for preparing polytetrahydrofuran, polytetrahydrofuran copolymers or diesters or monoesters of these polymers comprises polymerizing tetrahydrofuran in the presence of at least one telogen and/or comonomer over a heterogeneous catalyst comprisin... | 09/24/2002 |
| 6451845 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of Formula I having the structure ##STR1## wherein R1 and R2 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, halogen, perfluoroalkyl of 1-6 carbon atoms, cycloalkyl of 3-8 carbon atoms,... | 09/17/2002 |
| 6410754 | Photochromic spiropyrans, and compositions and articles containing same Novel spiropyran compounds, particularly with photochromic properties, are disclosed, as well as photochromic compositions and ophthalmic articles containing said compounds. The photochromes have been designed so as to have a high colorability, a high sen... | 06/25/2002 |
| 6399786 | Nonacyclic nodulisporic acid derivatives The present invention relates to novel nodulosporic acid derivatives, which are acaricidal, antiparasitic, insecticidal and anthelmintic agents.... | 06/04/2002 |
| 6387908 | Epoxysuccinamide derivatives Epoxysuccinamide derivatives of the formula (1): ##STR1## wherein R1 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or aralkyl; R2 is alkyl, alkenyl, alkynyl, aryl, or aralkyl; R3 is hydrogen, alkyl, alkenyl, alkynyl, aryl, a... | 05/14/2002 |
| 6359150 | Photochromic compound and optical function device using the same A novel diarylethene photochromic compound is provided. The photochromic compound is capable of forming an amorphous thin film by itself through a coating method and has an excellent thermostability. The amorphous thin film of the photochromic compound ca... | 03/19/2002 |
| 6331563 | N-Hydroxy-2-(Alkyl, Aryl, or Heteroaryl, Sulfanyl, Sulfinyl or Sulfonyl)-3-Substituted Alkyl, Aryl or Heteroarylamides as Matrix Metalloproteinase inhibitors Matrix metalloproteinases (MMPs) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenase... | 12/18/2001 |
| 6331635 | Taxoids, their preparation and pharmaceutical compositions containing them New taxoids of general formula (I): ##STR1## their preparation and pharmaceutical compositions containing them. The new products of general formula (I) in which Z represents a radical of general formula (II): ##STR2## display noteworthy antitumour and ant... | 12/18/2001 |
| 6284785 | 1-arenesulfonyl-2-aryl-pyrrolidine and pyridine derivatives 1-Arenesulfonyl-2-Aryl-pyrrolidine and pyridine derivatives having activity as ligands of metabotropic glutamate receptors of the formula ##STR1## are disclosed.... | 09/04/2001 |
