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| Number | Title | Issue Date |
| 8350066 | Process for the extraction of bioactive lignans with high yield and purity from sesame oil The present invention provides a process for the extraction and isolation of bioactive lignans with high yield and purity from Sesame oil by sequential extraction, crystallization, and saponification. The present invention provides a process for the production of hi... | 01/08/2013 |
| 8278468 | Furanose derivatives The invention relates to a process for preparing furanose derivatives, to furanose intermediates used in said process and to the use of said derivatives in the manufacture of atorvastatin. ... | 10/02/2012 |
| 8236970 | Vanillin acetals The invention relates to a sensory stimulant composition containing one or more of vanillin acetals represented by the general formula (1), and a flavor and fragrance composition, a beverage or food product, a fragrance or cosmetic product, a daily utensil product, ... | 08/07/2012 |
| 7521569 | Process to obtain dibenzylbutyrolactonic lignans, process to obtain synthetic derivatives from lignans bearing anti-Chagas chemoprophylactic and therapeutical activities The invention refers to a process to obtain lignans, especially to obtain cubebin and methylpluviatolide from leaves of Zanthoxylum naranjillo or Piper cubeba. It also refers to a process to obtain semi-synthetic derivatives of cubebin, especially dibe... | 04/21/2009 |
| 7317114 | Process to obtain dibenzylbutyrolactonic lignans, process to obtain synthetic derivatives from lignans bearing anti-Chagas chemoprophylactic and therapeutical activities The invention refers to a process to obtain lignans, especially to obtain cubebin and methylpluviatolide from leaves of Zanthoxylum naranjillo or Piper cubeba. It also refers to a process to obtain semi-synthetic derivatives of cubebin, especially dibe... | 01/08/2008 |
| 7309711 | Fungicidal agent combinations The invention relates to novel fungicidallly active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide of the formula and the active compounds listed in the disclosure. ... | 12/18/2007 |
| 7208169 | Biphenyl carboxamides The invention relates to novel biphenylcarboxamides of the formula (I) in which R1, R2, m, n, R3, Y and A are as defined in the disclosure, to a plurality... | 04/24/2007 |
| 7199127 | Purine nucleosides Disclosed are purine nucleoside compounds that are selective to A3 adenosine receptors and are useful for the treatment of cancer and inflammatory diseases. The compounds are shown by the following general formula (I), including isomers thereof: | 04/03/2007 |
| 7115596 | Thiazole compounds as integrin receptor antagonists derivatives The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of ... | 10/03/2006 |
| 7087768 | Fumagillol derivatives and preparing method thereof The disclosure relates to a fumagillol compound which can be usefully used not only as an angiogenesis inhibiting agent showing a superior angeogenesis inhibitory effect with less toxicity, but also as a cancer metastasis inhibitor and a therapeutic agent against ca... | 08/08/2006 |
| 7060840 | Catalytic asymmetric desymmetrization of prochiral compounds The present invention relates to methods for the synthesis of chiral non-racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral starting materials, e.g., meso anhydrides. The present invention also relates to catalysts for the aforementioned me... | 06/13/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 7001526 | Optical isomer separation method Methods for separation of two optical isomers in a racemate into its constituent isomers by statistical means are described, whereby the saturated racemate solution is first allotted into small samples by means of microfluidic or inkjet techniques to obtain small sa... | 02/21/2006 |
| 6994866 | Combinations of active ingredients, which exhibit insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in... | 02/07/2006 |
| 6943182 | Cyclopentabenzofuran derivatives and their use The invention relates to cyclopentabenzofuran derivatives, process for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-κB-dependent diseases and medicaments which contain the cyclopentabenzofur... | 09/13/2005 |
| 6867230 | Hygromycin A derivatives This invention relates to compounds of the formula and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3 and R10 | 03/15/2005 |
| 6849653 | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthri... | 02/01/2005 |
| 6844375 | 4-methylene-1,3-dioxolanes as cross-linking agents The invention relates to: 4-methylene-1,3-dioxolanes of the general formula (I) wherein R1 denotes hydrogen, C5-C6-cycloalkyl or C1-C4-alkyl; m and n, which may be the same o... | 01/18/2005 |
| 6723395 | Chiral compounds The invention relates to chiral compounds of formula I, to liquid crystal mixtures comprising at least one chiral compound of formula I, to chiral linear or crosslinked liquid crystal polymers obtainable by polymerizing ... | 04/20/2004 |
| 6686348 | Metalloprotease inhibitors A compound of formula (I): ##STR1## wherein: R1 represents hydrogen, halogen, alkyl or alkoxy, X represents oxygen, sulphur or NR wherein R represents hydrogen or alkyl, A represents any one of the groups described in the description, their isomers and a... | 02/03/2004 |
| 6649651 | Hexahydrofuro[2,3-B]furan-3-yl-n{3[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl) amino]-1-benzyl-2-hydroxypropyl}carbamate as retroviral protease inhibitor Novel bis-tetrahydrofuran benzodioxolyl sulfonamide compounds which are surprisingly effective protease inhibitors. The invention also relates to pharmaceutical compositions, methods of inhibiting retrovirus proteases, in particular multidrug resistant re... | 11/18/2003 |
| 6437133 | Method of catalytically removing a protective group containing an allyl group using a reducing agent A method of efficiently removing the protective group from a protected hydroxyl or amino group with an allyl derivative by one step reaction under neutral conditions. A protected hydroxyl or amino group is converted into a free hydroxyl or amino group in ... | 08/20/2002 |
| 6420393 | Cyclopentabenzofuran derivatives and their use The invention relates to cyclopentabenzofuran derivatives, processes for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-.kappa.B-dependent diseases and medicaments which contain the ... | 07/16/2002 |
| 6387431 | Dicarboalkoxy dioxolanes as flavoring agent releasing compounds The dicarboalkoxy dioxolanes of formula (I) are stable in acidic aqueous alcoholic and non-alcoholic beverages. Therefore they are useful in food products especially in beverages to stabilize the citral character of these products by releasing citral over... | 05/14/2002 |
| 6342497 | 2"-deoxy hygromycin derivatives This invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1 and R2 are as defined herein. The compounds of formula 1 are antibacterial and antiprotoz... | 01/29/2002 |
| 6319946 | Inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical ... | 11/20/2001 |
| 6313317 | Ruthenium-phosphine complex and method for producing the same Disclosed is a ruthenium-phosphine complex usable as the catalyst giving a high enantiomer excess in an asymmetric reaction and a method for producing the complex. The ruthenium-phosphine complex is represented by formula (1): [{(RuX(L)}2 (μ-X... | 11/06/2001 |
| 6294674 | Dibenzofuran sulfonamide matrix metalloproteinase inhibitors The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds. ##STR1## wherein Q is an un-natural amino acid. More particurlarly, the present ... | 09/25/2001 |
| 6294568 | 5-arylpyrrole derivatives The present invention provides compounds represented by the general formula (I): ##STR1## and a salt thereof, and anti-inflammatory agents and antitumor agents containing the compounds as the active ingredients.... | 09/25/2001 |
| 6228547 | Bis(3,4-methylenedioxyphenylamino) derivatives and electrophotographic photoreceptor containing the derivatives Disclosed are novel compounds useful in electrophotographic photoreceptors as charge-transporting materials having good miscibility with binder polymers and capable of forming a thin stable organic film having a high concentration; and an electrophotograp... | 05/08/2001 |
| 6218135 | 1,2-dioxetane derivative The present invention has its objects to provide a compound not only which is easy to handle, thermally stable, and high in emission efficiency, but also which can show high emission efficiency without coexisting enhancer in the system even in a protic so... | 04/17/2001 |
| 6162932 | Stereoselective synthesis of endothelin receptor antagonists The present invention is directed to chiral intermediates in a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A). ##STR1##... | 12/19/2000 |
| 6124484 | Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis The present invention provides a method for the preparation of triarylmethyl protecting group reagents. The reagents are prepared from reaction effluent from the cleavage step of oligonucleotide synthetic regimes.... | 09/26/2000 |
| 6080862 | Stereoselective synthesis of endothelin receptor antagonists The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates ##STR1##... | 06/27/2000 |
| 6017956 | N,N-disubstituted amic acid derivatives The present invention relates to a compound of the formula (I): ##STR1## wherein Ar1, Ar2, Ar3 and Ar4 represent an aryl group or a heteroaromatic ring group; A represents a hydrocarbon group which may be s... | 01/25/2000 |
| 6013244 | 21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing them Compounds of the pregnane series are described having general formula (I) or their solvates in which R1 individually represents --OC(.dbd.O)C1-6 alkyl; R2 individually represents hydrogen, methyl (which may be in the ... | 01/11/2000 |
| 5998408 | Triterpene derivatives with immunosuppressant activity The compounds of Formula I ##STR1## are useful as immunosuppressive agents.... | 12/07/1999 |
| 5981573 | N,N-disubstituted amic acid derivatives A compound represented by general formula (I) or a pharmaceutically acceptable salt or ester thereof: [wherein each of Ar1, Ar2, Ar3 and Ar4 is an aryl group or an aromatic heterocyclic group; A1 is a... | 11/09/1999 |
| 5919786 | N,N-disubstituted amic acid derivatives The present invention relates to a compound of the formula (I): ##STR1## wherein Ar1, Ar2, Ar3 and Ar4 represent an aryl group or a heteroaromatic ring group; A represents a hydrocarbon group which may be s... | 07/06/1999 |
