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| Number | Title | Issue Date |
| 8183396 | Process for the working-up of a vitamin E- and vitamin E-acetate- containing mixture or products stream The invention relates to a process for the working-up of a vitamin E (VE)- and/or vitamin E acetate (VEA)-containing product stream, which is substantially characterized by purification of a vitamin E-containing product stream, acetylation of at least a part of the ... | 05/22/2012 |
| 7718814 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having a structural formula where X and Y independently are oxygen, nitrogen or sulfur; R1 is alkyl, alkenyl, alkynyl, aryl, h... | 05/18/2010 |
| 7652155 | Diamine derivative, production process therefor and antioxidant The present invention relates to a compound represented by formula (1): (wherein, R1, R2, R3 and R4 respectively and independently represent a hydrogen atom or a C1-6 alkyl group, and n represents an integer of 1... | 01/26/2010 |
| 7626046 | Manufacture of α-tocopherol A process for the manufacture of (all-rac)-α-tocopherol comprises submitting isolated, purified phytyltrimethylhydroquinone to acid catalysis, thereby promoting ring closure to (all-rac)-α-t-tocopherol. The process can be conducted in the absence or presence of an... | 12/01/2009 |
| 7429411 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition The compound (1) according to the invention has general solid-state properties necessary for a compound, stability against heat, light and the like, a suitable optical anisotropy, a suitable dielectric anisotropy, and excellent compatibility with other liquid crysta... | 09/30/2008 |
| 7410998 | Inhibitors of NADH:ubiquinone oxidoreductase Benzopyran-based inhibitors of NADH:ubiquinone oxidoreductase for inhibiting the growth of cancer cells. ... | 08/12/2008 |
| 7396855 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 07/08/2008 |
| 7321053 | Process for the manufacture of tocyl and tocopheryl acylates A process for the manufacture of a tocyl acylate or a tocopheryl acylate comprises reacting tocol or a tocopherol with an acylating agent in the presence of a solid heterogeneous Brönsted acid catalyst, said catalyst being an inorganic Brönsted acid on a solid car... | 01/22/2008 |
| 7312232 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having the structural formula wherein X is oxygen, nitrogen or sulfur; Y is selected from the group consisting of oxygen, nitrogen and sulfur wherein w... | 12/25/2007 |
| 7309755 | Method of producing polycarbonate articles by rotation molding and rotation molded articles made by the method A method for making a polycarbonate article is described wherein the article is made by rotation molding a melt polycarbonate having a weight average molecular weight from 25,000 to about 36,000. The melt polycarbonate is produced by transesterifying a diaryl carbon... | 12/18/2007 |
| 7300954 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having a structural formula where X and Y independently are oxygen, nitrogen or sulfur; R1 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbo... | 11/27/2007 |
| 7297715 | PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders A class of chromane and chromene compounds having the structure shown below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment and control of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other ... | 11/20/2007 |
| 7247355 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition The present invention relates to a compound having a chroman ring, which has good thermal and optical stability, adequate optical anisotropy, adequate dielectric anisotropy and superior compatibility with other liquid crystal compounds, a liquid crystal composition ... | 07/24/2007 |
| 7226644 | Chroman derivative and liquid-crystal composition containing the compound The present invention relates to a liquid crystal compound which has negative dielectric anisotropy and a large absolute value thereof; and a liquid crystal display element which contains the compound as a constituent element and has a negative value of dielectric a... | 06/05/2007 |
| 7148240 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular... | 12/12/2006 |
| 7144919 | Polyoxyethylene-polyoxypropylene vitamin E and process for preparation thereof The present invention relates to polyoxyethylene-polyoxypropylene (POE-POP) vitamin E, which is prepared from vitamin E by polyethoxylation and polypropoxylation, and a method for preparing the same. The POE-POP vitamin E has a high surface activity and an excellent... | 12/05/2006 |
| 7138532 | Color-stable, low impurity tocopherol compositions and processes for preparing the same Processes for preparing color-stable, low-impurity tocopherol compositions are described, wherein the processes comprise: (a) providing a protecting group-substituted tocopherol compound, for example an acetate of a natural-source tocopherol compound; (b) purifying ... | 11/21/2006 |
| 7115657 | Bifunctional agents possessing antioxidant and antiarrhythmic activity The present invention relates to novel bifunctional agents possessing antioxidant and antiarrhytmic activity, methods for the synthesis of the same and their applications in treating ischemia-reperfusion injury, as well as a variety of disorders related to free radi... | 10/03/2006 |
| 7105686 | Manufacture of tocol, tocol derivatives and tocopherols The present invention is concerned with a novel process for the manufacture of tocol, tocol derivatives and tocopherols, especially α-tocopherol, by the reaction of a hydroquinone featuring 0 to 3 methyl groups, especially 2,3,5-trimethylhydroquinone, with isophyto... | 09/12/2006 |
| 7045164 | Soybean processing Methods are provided for forming soy germ concentrate in a soybean processing operation that produces soy bean oil and soybean meal. ... | 05/16/2006 |
| 7034054 | Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols The present invention provides method for the treatment of a symptom of neuronal damage associated with cerebral ischemia comprising administering gamma-, beta-, or delta-tocopherol enriched tocopherol compositions. ... | 04/25/2006 |
| 6987194 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives of Formula I are disclosed. These compounds provide unexpected insecticidal activity across a spectrum of insect pests combined with desirable physical properti... | 01/17/2006 |
| 6974685 | High production method of prenyl alcohol using saccharomyces cells The present invention provides a high production method of prenyl alcohol, which comprises culturing prenyl alcohol-producing cells in a medium with an increased sugar content in the presence of at least one member selected from the group consisting of a surfactant,... | 12/13/2005 |
| 6872838 | Water soluble prodrugs of hindered alcohols The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals. ... | 03/29/2005 |
| 6867307 | Intermediates for use in the preparation of vitamin E Intermediate compounds which can be used in the preparation of phytone and Vitamin E, a process for the preparation thereof, and a process for the preparation of phytone and Vitamin E from these intermediate compounds. ... | 03/15/2005 |
| 6841536 | Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof Disclosed is a prodrug of the formula: where A is a sulfur or a selenium, and R is derived from a mono- di- or oligo- saccharide. Also disclosed is a prodrug of the formula: | 01/11/2005 |
| 6818666 | Bi-aromatic compounds linked via a heteroethylene radical, and pharmaceutical and cosmetic compositions using them Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use. ... | 11/16/2004 |
| 6790965 | Combinatorial dihydrobenzopyran library Combinatorial libraries are disclosed which are represented by Formula I: (T′—L)q—Ŝ—C(O)—L′—II′ I wherein: Ŝ is a solid support; T′—L— is an identifier residue; and —L′—II′ is a l... | 09/14/2004 |
| 6784303 | Method for continuously acylating chromanol ester derivatives A process is described for continuously preparing chromanol ester derivatives, in particular for continuously preparing carboxylic esters of tocopherols and tocotrienols by continuous acylation with carboxylic acids or carboxylic anhydrides. ... | 08/31/2004 |
| 6770672 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having the structural formula wherein X is oxygen, nitrogen or sulfur; Y is selected from the group consisting of oxygen, nitrogen and sulfur wherein when Y is... | 08/03/2004 |
| 6706757 | Chroman derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ... | 03/16/2004 |
| 6703384 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having a structural formula ##STR1## where X and Y independently are oxygen, nitrogen o r sulfur; R1 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, carboxylic acid, carboxylate, ... | 03/09/2004 |
| 6599933 | Tocotrienol derivative, process for producing the same and γ-CEHC delivering agent The object of the present invention is to provide a tocotrienol derivative which is highly water-soluble and shows high bioavailability in the living body and γ-CEHC delivering agent. ##STR1## (A tocotrienolcarboxylic acid ester derivative represented by... | 07/29/2003 |
| 6596758 | Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process The present invention relates to benzopyrans and benzoxepines of formula (I), wherein X, A, R1, R2 and (R)p have the meanings as given in claim 1, which can be used in the treatment of dislipidaemias, atherosclerosis and d... | 07/22/2003 |
| 6482961 | Method of making (all-rac)--tocopherol The present invention is a method of making (all-rac)--tocopherol in a reaction having the following steps: a) reacting trimethylhydroquinone and a phytol selected from the group consisting of isophytol and phytol in the presence of a bis(perfluorinated... | 11/19/2002 |
| 6471954 | Method for the production and use of a cream containing vitamin-A A method for the production of a vitamin-A containing cream comprising the following steps: a) a first mixture--consisting of a number of water-soluble substances such as glycerine and extracts of plants--is mixed together during heating and comminution u... | 10/29/2002 |
| 6452023 | Process for preparing d,l--tocopherol A process for the manufacture of d,l--tocopherol by the acid-catalyzed condensation of trimethylhydroquinone with isophytol or phytol in ethylene or propylene carbonate or a mixture of both carbonates, or in a mixture of one or both of the carbonat... | 09/17/2002 |
| 6441199 | Process for the production of -tocopherol acetate by condensation of trimethylhydroquinone with isophytol with recycling of an acetic catalyst solution A process for the production of -tocopherol acetate in a recirculating process by condensation of trimethylhydroquinone and isophytol in the presence of a catalyst system of a zinc halide and an aqueous protonic acid and, optionally, an elemental m... | 08/27/2002 |
| 6429320 | Processes for the purification of tocopherol and/or sterol compounds and compositions containing orthoborate ester mixtures Processes for purifying compounds are disclosed which include reacting (i) a mixture of at least one tocopherol compound or sterol compound, and an alcohol having from about 10 to 30 carbons with (i) one or more boron-containing compounds to form a second... | 08/06/2002 |
| 6423744 | Method of diminishing the adverse effects of interleukin-2 A method and composition for preserving or enhancing the beneficial effects of interleukin-2 (IL-2) while simultaneously mitigating the adverse effects of IL-2 on a subject is disclosed. The method involves administering an amount of a leukotriene B4... | 07/23/2002 |
