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| Number | Title | Issue Date |
| 7875736 | Intermediate compounds and processes for the preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran Disclosed herein is a compound of formula (I): wherein: Bn represents benzyl; Me represents methyl; and Y represents an oxygen atom or a CH2 grou... | 01/25/2011 |
| 7696363 | Preparation of flavonoid compounds Disclosed is an improved method for preparing the isoflavonoid compound (+/−)-equol, the method comprising reducing an organic diester of the isoflavone daidzein under hydrogen-transfer conditions using palladium hydroxide catalyst. ... | 04/13/2010 |
| 7485735 | Process for selectively extracting procyanidins A process is described for selectively extracting cocoa procyanidins from an aqueous mixture of cocoa polyphenols by using a particular sequence of solvents to extract selected procyanidin monomers and/or oligomers. The solvents are n-butyl acetate, ethyl acetate, m... | 02/03/2009 |
| 7435722 | Non-toxic crosslinking reagents to resist curve progression in scoliosis and increase disc permeability A method of improving the resistance of collagenous tissue to mechanical degradation in accordance with the present invention comprises the step of contacting at least a portion of a collagenous tissue with an effective amount of a crosslinking reagent. Methods and ... | 10/14/2008 |
| 7432297 | Reaction product of resorcin and methyl ethyl ketone A compound of the following formula (I) or (II) (in the formula (I), n represents an integer of 0 to 2) (in the formula (II), m represents an integer of 0 to 2). ... | 10/07/2008 |
| 7429411 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition The compound (1) according to the invention has general solid-state properties necessary for a compound, stability against heat, light and the like, a suitable optical anisotropy, a suitable dielectric anisotropy, and excellent compatibility with other liquid crysta... | 09/30/2008 |
| 7427686 | (3R, 4R)-trans-3, 4-diarylchroman derivatives and a method for the prevention and/or treatment of estrogen dependent diseases The present invention relates to compounds of the formula I in which substituents R2 and R3 are arranged in trans-configuration: wherein: R1 is H or C1-C6 ... | 09/23/2008 |
| 7365113 | Phosphate ester flame retardants from resorcinol-ketone reaction products Flavan-based and spirodichroman compound-based phosphate esters prepared by reacting flavans and spirodichroman compounds with phosphorus oxychloride, monophenyl dichlorophosphate, or diphenyl chlorophosphate compounds are described. The flavans and spirodichroman c... | 04/29/2008 |
| 7332260 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them The present invention relates to novel compounds of the naphthopyran type which have an annelated carbocycle in position 5,6. These compounds are of formula (I) given below: in which A is an alicyclic ring which ... | 02/19/2008 |
| 7329654 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders mediated by one or more estrogen receptors and processes for their prepar... | 02/12/2008 |
| 7312344 | Dimeric isoflavones A compound of the general formula (I) or (II) wherein X is O, NR4 or S and R1-R8 are as defined in the specification ... | 12/25/2007 |
| 7282598 | Synthetic methods for preparing procyanidin oligomers Processes are disclosed for the production of linear and branched procyanidin oligomers having “n” procyanidin monomeric units where n is 2 to 18. The processes include coupling protected, activated monomers with an unprotected monomer to produce a partially pro... | 10/16/2007 |
| 7250120 | Benzo-, naphtho- and phenanthrochromene substituted by carbamated or ureated phenyls, preparation thereof and compositions and articles containing them Disclosed are novel benzo-, naphtho- and phenanthrochromenes substituted by carbamated or ureated phenyls having the following general formula (I): wherein R1 represents a group | 07/31/2007 |
| 7247355 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition The present invention relates to a compound having a chroman ring, which has good thermal and optical stability, adequate optical anisotropy, adequate dielectric anisotropy and superior compatibility with other liquid crystal compounds, a liquid crystal composition ... | 07/24/2007 |
| 7226644 | Chroman derivative and liquid-crystal composition containing the compound The present invention relates to a liquid crystal compound which has negative dielectric anisotropy and a large absolute value thereof; and a liquid crystal display element which contains the compound as a constituent element and has a negative value of dielectric a... | 06/05/2007 |
| 7202247 | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the ... | 04/10/2007 |
| 7126014 | Synthesis of epecatechin-4α, 8-epicatechin and -catechin dimers and derivatives thereof Oligomeric procyanidins containing 4α-linked epicatechin units are rare in nature and have hitherto not been accessible through stereoselective synthesis. Provided herein is the preparation of the prototypical dimer, epicatechin-4α,8-epicatechin, by reaction of th... | 10/24/2006 |
| 7105679 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders mediated by one or more estrogen receptors and processes for their prepar... | 09/12/2006 |
| 7102020 | Total synthesis of daurichromenic acid The present invention provides a method to prepare 2H-benzo[6]pyrans, such as the anti-HIV natural product daurichromenic acid (1a), by microwave-assisted tandem aldol reaction of a phenolic enolate followed by intramolecular SN2′ type cyclization to form the 2H-b... | 09/05/2006 |
| 7045514 | Therapeutic heterocyclic compounds Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementi... | 05/16/2006 |
| 7045155 | Dietary supplements comprising soy hypocotyls containing at least one isoflavone Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules for promoting health in cases of cancer, pre-menstrual syndrome, menopa... | 05/16/2006 |
| 7009062 | Process for the preparation of flavone derivatives The invention relates to a process for the preparation of flavone derivatives in which a 2-hydroxyacetophenone compound is metallated using a lithium compound at low temperatures and subsequently reacted with a keto compound, and where the ratio of the molar equival... | 03/07/2006 |
| 6987098 | Health supplement Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules for promoting health in cases of cancer, pre-menstrual syndrome, menopa... | 01/17/2006 |
| 6951883 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof 2H-1-Benzopyran derivatives, processes for their preparation and use thereof for the preparation of pharmaceutical compositions for the prevention and treatment of postmenopausal pathologies. ... | 10/04/2005 |
| 6849746 | Synthetic methods for polyphenols A process is disclosed for the production of polyphenol oligomers having n polyphenol monomeric units, n being an integer from 2-18. The process includes coupling of a protected polyphenol, having protected phenolic hydroxyl groups, with a C-4 functionalized polyphe... | 02/01/2005 |
| 6849646 | Chromenone and chromanone derivatives as integrin inhibitors The invention relates to compounds having formula (I), wherein R1, R2, R3, R4, R5, R7, R8, R11, Z, m and n have the meaning cited in... | 02/01/2005 |
| 6849649 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase The invention relates to compounds of formula (I) for treating for example sexual dysfunction, wherein R1 is optionally substituted C1-6alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C1-6alk... | 02/01/2005 |
| 6844336 | 4-fluoroalkyl-2h-benzopyrans with anti-estogenic activity This invention describes the new 4-fluoroalkyl-2H-benzopyrans of general formula I, in which Z is a straight-chain or branched-chain alkyl group with up to 5 carbon atoms that is fluo... | 01/18/2005 |
| 6812225 | Therapeutic heterocyclic compounds Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementi... | 11/02/2004 |
| 6803129 | Organic light emitting diode and organic luminescent materials thereof The present invention relates to an organic light emitting diode (OLED) device, comprising an anode disposed on a substrate, an organic EL layer disposed on the anode and a cathode disposed on the organic EL layer. The material of the organic EL layer comprises a co... | 10/12/2004 |
| 6770672 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having the structural formula wherein X is oxygen, nitrogen or sulfur; Y is selected from the group consisting of oxygen, nitrogen and sulfur wherein when Y is... | 08/03/2004 |
| 6747059 | Composition for, and methods of, anti-platelet therapy Cocoa extracts which include procyanidin monomers and their oligomers are useful in the modulation of inflammatory pathways, in the maintenance of the vascular health of a mammal and as an antibacterial treatment. The liquid or dry cocoa extracts can be included in ... | 06/08/2004 |
| 6696485 | Procyanidin and cyclo-oxygenase modulator compositions This invention relates to compositions comprising a cyclo-oxygenase modulator in combination with cocoa procyanidin monomers and/or oligomers, wherein the cyclo-oxygenase modulator is a non-steroidal anti-inflammatory drug such as aspirin. Such compositio... | 02/24/2004 |
| 6660756 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase The invention relates to compounds of formula (I) for treating for example sexual dysfunction, wherein R1 is optionally substituted C1-6 alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C... | 12/09/2003 |
| 6645951 | Benzopyran or thiobenzopyran derivatives The present invention provides novel benzopyran compounds, pharmaceutically acceptable salts thereof and stereoisomers thereof where the benzopyran compounds of the invention are compounds according to Formula I: ##STR1## The present invention further pro... | 11/11/2003 |
| 6642212 | Health supplements containing phyto-oestrogens, analogues or metabolites thereof Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Diadzein, Formononectin and Biochanin A. These compositions may be used as food additives, tablets or capsules for promoting health in cases of cancer, pre-m... | 11/04/2003 |
| 6610733 | Optically active chroman and thiochroman derivatives The present invention includes a compound having the following general formula (1): ##STR1## in which x represents an oxygen atom or a sulfur atom, m represents an integer of 2 to 14, and n represents an integer of 2 to 7, or hydrates or pharmaceut... | 08/26/2003 |
| 6555571 | 3-methyl -chromane or thiochromane derivatives The present invention relates to 3-methyl-chromane or thiochromane derivatives, pharmaceutically acceptable salts, stereoisomers or hydrates thereof, and an anti-estrogenic pharmaceutical composition which comprises the above compound as an active compone... | 04/29/2003 |
| 6552068 | 3-ethyl-, 3-propyl- or 3-butyl-chroman and thiochroman derivatives A compound having the following general formula (1): ##STR1## in which R1 represents an ethyl group, etc.; R2 represents a hydrogen atom, etc.; R3 represents a C1 -C5 perhalogenoalkyl group, etc.; each of R | 04/22/2003 |
| 6552069 | 3-methyl-chroman and -thiochroman derivatives The present invention provides a compound having the following general formula (1): ##STR1## in which R1 represents a hydrogen atom, etc.; R2 represents a C3 -C3 perhalogenoalkyl group, etc.; each of R3 an... | 04/22/2003 |
