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| Number | Title | Issue Date |
| 7385067 | Process for the preparation of compounds having a CFO bridge The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which a) an acid is added onto at least one ketene dithioketal, b) the... | 06/10/2008 |
| 7157589 | One step process for the preparation of anticonvulsant derivatives The present invention is directed to a one-step process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein X, R1, R3, R | 01/02/2007 |
| 6962938 | Spiro-cyclic β-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-α converting enzyme (TACE) The present application describes novel spiro-cyclic β-amino acid derivatives of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 3-13 membered carbocycle or heterocycle, ring C forms ... | 11/08/2005 |
| 6756497 | Benzoic acid derivatives and processes for the preparation thereof Benzoic acid derivatives useful as intermediates for the preparation of drugs and agricultural chemicals, particularly compounds having herbicidal activity; and easy and economical processes for the preparation of the same. The processes are specifically those repre... | 06/29/2004 |
| 6673937 | Syntheses and methods of use of new antimitotic agents Oxidative cyclization of bis-naphthyl ethers allows concise total syntheses of palmarumycin CP1 and deoxypreussomerin A in 8-9 steps and 15-35% overall yield from 5-hydroxy-8-methoxy-1-tetralone. A small library of palmarumycin analogs was crea... | 01/06/2004 |
| 6315928 | Spirofluorenopyrans The present invention relates to specific photochromic 3H-naphtho[2,1-b]pyran derivatives and to their use in plastics of all types, especially for ophthalmic purposes. In particular, the present invention relates to spiro compounds derived from naphthopy... | 11/13/2001 |
| 6149841 | Photochromic benzopyrano-fused naphthopyrans Described are novel photochromic benzopyrano-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted benzopyran group fused to one side of the naphtho portion of the naphthopyran and having certain ... | 11/21/2000 |
| 6022495 | Photochromic benzopyrano-fused naphthopyrans Described are novel photochromic benzopyrano-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted benzopyran group fused to one side of the naphtho portion of the naphthopyran and having certain ... | 02/08/2000 |
| 5786496 | High oxidation state metal oxo complexes of the PHAB ligand The present invention provides a new tetradentate bis-amido bis-alkoxo, 1,2-(bis-2,20diphenyl-2-hydroxyethanamido)benzene (H4 PHAB) and various derivatives thereof. This ligand is able to stabilize high valen metal oxo complexes by providing st... | 07/28/1998 |
| 5703249 | Bicycloaliphatic 2-methylene-1,3-dioxepanes The present invention relates to novel bicycloaliphatic 2-methylene-1,3-dioxepanes, which are suitable as starting materials for the preparation of polymers and copolymers, preferably of composite and dental materials. The 2-methylene-1,3-dioxepanes accor... | 12/30/1997 |
| 5663393 | Chiral catalysts and epoxidation reactions Chiral catalysts for enantioselectively epoxidizing a prochiral olefin and for enantioselectively oxidizing a prochiral sulfide are disclosed, together with methods of using such catalysts. In accordance with one aspect of the invention, the catalyst is a... | 09/02/1997 |
| 5645767 | Photochromic indeno-fused naphthopyrans Described are novel photochromic indeno-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted indeno group, the 2,1 positions of which are fused to the f side of the naphtho portion of the naphtho... | 07/08/1997 |
| 5463087 | Substituted derivatives of deoxymyoinositol, process for their preparation and their use in medicaments A process for the preparation of a compound. That compound is converted to a novel compound of the formula ##STR1## in which R1, R2 and R5 each independently is alkyl of 3 to 14 carbon atoms, which is used to make nov... | 10/31/1995 |
| 5387700 | Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-O-(1-methylethylidene)-ଲ-D-fructopyranose and (1-methylcyclohexyl)methanol A process for producing chlorosulfate and sulfamate esters of 2,3:4,5-bis-O-(1-methylethylidene)-ଲ-D-fructopyranose and (1-methylcyclohexyl)methanol is disclosed. The process involves a two step procedure involving in the first step reacting of an a... | 02/07/1995 |
| 5354495 | Alkenoylcarbamate compounds as elasticity, adhesion, and dispersibility enhancer A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imi... | 10/11/1994 |
| 4965257 | Pesticidal compounds Bicyclo-[2,2,1]-heptanes, bicyclo-[2,2,2]-octanes and bicyclo-[2,2,3]-nonanes, having 2 or 3 ring hetero atoms selected from O, S and N, substituted at the 1-position by a 4-alkynylphenyl group and at the 4-position and optionally at the 3 and/or 5-positi... | 10/23/1990 |
| 4927963 | Novel processes for the synthesis of certain bicyclo(4.2.0)octane derivatives with valuable therapeutic properties A process for preparing compounds represented by the formula ##STR1## wherein: X is hydrogen or lower alkoxy; Y is hydrogen, exo-(lower alkyl) or endo-(lower alkyl); n is an integer from 2-4; R2 is hydrogen or methyl; and R3 is linear or ... | 05/22/1990 |
| 4925956 | Novel process for manufacturing optically active carbacyclin intermediates The invention relates to a process for manufacturing optically active carbacyclin intermediate products from racemic cis-bicyclo[3.3.0]octane-2-carboxylic acids. This process makes it possible in an advantageous way to produce important intermediates for ... | 05/15/1990 |
| 4841075 | Method of preparing acetal or ketal A method of preparing an acetal or ketal from a corresponding aldehyde or ketone is disclosed. A hydrous oxide of an element of Group IV of the Periodic Table is used as a catalyst, and the aldehyde or ketone is caused to react with an alcohol. The hydrou... | 06/20/1989 |
| 4792606 | Process for the preparation of dimeric aromatic acyl cyanides A process for the preparation of a dimeric aromatic acyl cyanide of the formula ##STR1## in which Ar is optionally substituted phenyl, naphthyl or hetaryl, comprising reaction an acyl halide of the formula in which Hal is fluorine, chlorine or bromine, wi... | 12/20/1988 |
| 4599327 | Dibenzo[bd]pyran derivatives, process for the preparation thereof and pharmaceutical compositions containing same 2,6-di-O-methyl-beta-cyclodextrin complexes of compounds of the formula (1a) ##STR1## wherein R2' stands for C1 to C12 alkyl or a group of the formula ##STR2## in which R11 is C1 to C | 07/08/1986 |
| 4582916 | Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol Sulfamates of the following formula (I): ##STR1## wherein X is O or CH2 and R1, R2, R3, R4 and R5 are as herein defined have been found to exhibit anticonvulsant activity and are thus ... | 04/15/1986 |
| 4513006 | Anticonvulsant sulfamate derivatives Sulfamates of the following formula (I): ##STR1## wherein X is O or CH2 and R1, R2, R3, R4 and R5 are as herein defined have been found to exhibit anticonvulsant activity and are thus ... | 04/23/1985 |
| 4510159 | (+)-Cyanidan-3-ol derivatives, pharmaceutical preparations that contain such compounds, and the use of the latter to treat liver or venous diseases Compound of the formula ##STR1## in which R and R' represent hydrogen or an optionally substituted hydrocarbon radical or acyl radical, R1 represents hydrogen or an optionally substituted hydrocarbon radical of aliphatic or aromatic charac... | 04/09/1985 |
| 4331602 | Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor Compounds having the formula ##STR1## wherein ##STR2## R1 is hydrogen, benzyl or alkanoyl, X is C2-4 alkylene; and Z-W is alkyl, phenylalkyl or pyridylalkyl which can have an oxygen atom as part of the alkyl chain and their... | 05/25/1982 |
| 4235913 | 9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans 9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans wherein the substituent is hydrogen, methyl, hydroxymethyl, formyl, carboxy, carbamyl, amino, mono- and di-alkylamino, alkanoylamino, phenalkylsulfonamido or alk... | 11/25/1980 |
| 4176124 | Silicon-modified phthalic acid derivatives The invention relates to Si-modified phthalic acid derivatives (acids, esters and anhydrides) of the formula I ##STR1## in which R1 and R2 independently of one another are --OH, alkoxy with 1-12 C atoms or phenoxy or R1 | 11/27/1979 |
| 4165323 | 9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans and intermediates therefor 9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans wherein the substituent is hydrogen, methyl, hydroxymethyl, formyl, carboxy, carbamyl, amino, mono- and di-alkylamino, alkanoylamino, phenalkylsulfonamido or alk... | 08/21/1979 |
| 4143139 | 9-Hydroxydibenzo[b,d]pyrans and intermediates 9-Hydroxydibenzo[b,d]pyrans useful as analgesics, hypotensives, immunosuppressants, tranquilizers; as anti-secretory and anti-anxiety drugs; intermediates therefor and derivatives thereof having the formulae ##STR1## wherein R is hydrogen or alkanoyl... | 03/06/1979 |
| 4119640 | Polymerizable epoxide-modified compositions Polymerizable reaction product mixtures are prepared by the reaction of an epoxide of a long chain (1) unsaturated fatty oil or (ii) unsaturated fatty acid or ester thereof with a mixture of (a) acrylic acid or methacrylic acid, (b) a diepoxide, and (c) a... | 10/10/1978 |
| 4118559 | 9-Hydroxyhexahydrodibenzo[O,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans and intermediates therefor 9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans wherein the substituent is hydrogen, methyl, hydroxymethyl, formyl, carboxy, carbamyl, amino, mono- and di-alkylamino, alkanoylamino, phenalkylsulfonamido or alk... | 10/03/1978 |
| 4100174 | Process for the preparation of 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)acetic, propionic and butyric acids and intermediates 2-(5H-Dibenzo[a,d]cyclohepten-5-on-2-yl) acetic, propionic and butyric acids, are prepared from glycidonitrile intermediates.... | 07/11/1978 |
| 4080334 | Intermediates in the total synthesis employing substituted isoxazole derivatives The intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a route for the preparation of pharmaceutica... | 03/21/1978 |
| 4077996 | Process for the preparation of trans-deca hydronaphthalene derivatives A process for the preparation of trans-decahydronaphthalene compounds of Formula I ##STR1## wherein X is lower alkyl, --(CH2)3 --Z--R2, ##STR2## --(CH2)3 COOR4, or --(CH2 | 03/07/1978 |
| 4073817 | Process for the manufacture of perfluoroalkyl iodide-olefine adducts A process for the manufacture of perfluoroalkyl iodide adducts is provided, wherein a perfluoroalkyl iodide is reacted with an olefine in the presence of an amine and a metal salt of groups Ia to IVa or Ib to VIIIb of the periodic system, the amine and me... | 02/14/1978 |
| 4044004 | Total steroid synthesis employing substituted isoxazole derivatives The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of p... | 08/23/1977 |
| 3985771 | Total steroid synthesis employing substituted isoxazole derivatives The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-nor-steroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of ... | 10/12/1976 |
| 3984473 | Stereospecific total steroidal synthesis via substituted C/D-trans indanones Total synthesis of known progestationally active steroidal materials. The steroids can be synthesized depending on the particular starting reactants selected by employing as intermediates bicyclic compounds of the formula ##SPC1## Wherein m is an integer ... | 10/05/1976 |
| 3978088 | Cyclic acetals containing epoxide groups Cyclic acetals of 2-epoxy-propoxy-pivaldehydes. They can be used by themselves, if they contain two or more epoxy groups, or as reactive diluents in a mixture with other epoxide resins, and they give mouldings of excellent mechanical properties on curing ... | 08/31/1976 |
| 3978087 | Cyclic acetals containing epoxide groups Cyclic acetals of 2-epoxy-propoxy-pivaldehydes. They can be used by themselves, if they contain two or more epoxy groups, or as reactive diluents in a mixture with other epoxide resins, and they give mouldings of excellent mechanical properties on curing ... | 08/31/1976 |
