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| Number | Title | Issue Date |
| 7102019 | Cosmetic and pharmaceutical preparations comprising ascorbic acid derivatives An ascorbic acid derivative of the formula Ia: where the variables independently of one another have the following meanings: R1 and R2 independently of one anoth... | 09/05/2006 |
| 6388098 | Process for preparing ascorbic acid-2-monophosphate salt A process for preparing a high-purity ascorbic acid-2-monophosphate salt in a convenient manner and in a high yield, comprising hydrolyzing an ascorbic acid-2-polyphosphate or a salt thereof in the presence of magnesium ion at a pH of 7 or more.... | 05/14/2002 |
| 6169187 | Process for recovery of ascorbic acid The invention provides a process for the recovery of ascorbic acid from a feed containing at least one precursor of ascorbic acid comprising converting the precursor into at least one product, the at least one product being ascorbic acid in an organic ext... | 01/02/2001 |
| 5916915 | Water-in-stable L-ascorbic acid derivative and a method for preparation thereof, and a skin-whitening cosmetic composition containing the same Disclosed herein are a L-ascorbic acid derivative having an improved water-in-stability, represented by a following general formula (I): ##STR1## and a method for preparation thereof, and to a skin-whitening cosmetic composition containing the same a... | 06/29/1999 |
| 5863939 | Creatine ascorbates and a method of producing them Creatine ascorbates are described which have the general formula (I) (creatine)z (ascorbate)y (H2 O)n (I) where z=1 to 100 y=1 to 100 and n=0 to 20. These creatine ascorbates, which can be produced by way of the relative... | 01/26/1999 |
| 5679801 | Tetronic and thiotetronic acid derivatives as phospholipase A2 inhibitors There are disclosed compounds of the formula: ##STR1## wherein X is --CH2 R; Y is --O-- or --S--; R1 and R2 are each, independently, hydrogen or lower alkyl; or a pharmaceutically acceptable salt thereof; which by virtue of the... | 10/21/1997 |
| 5656662 | Synthesis of optically pure 4-alkenyl- or 4-alkanyl-2-hydroxytetronic acids The present invention relates to a method for synthesis of optically pure 4-alkenyl or 4-alkanyl-2-hydroxytetronic acids from an optically pure aldehyde. The invention further relates to the use of such optically pure compounds as potent inhibitors of pla... | 08/12/1997 |
| 5516919 | Process for producing ascorbic acid derivative Metal salts or substitutted or non-substituted ammonium salts of ascorbic acid derivatives can be produced in high yield by treating an acidic aqueous solution containing ascorbic acid-2-phosphate or ascorbic acid-2-sulfate with a porous adsorbent such as... | 05/14/1996 |
| 5504108 | Optically pure 4-aryl-2-hydroxytetronic acids The present invention relates to a method for synthesis of optically pure stereogenically labile 4-aryl-2-hydroxytetronic acids from an optically pure aidehyde. The invention further relates to the use of such optically pure compounds as potent inhibitors... | 04/02/1996 |
| 5504107 | Optically pure 4-alkenyl- or 4-alkanyl-2-hydroxytetronic acids and pharmaceutical use thereof The present invention relates to a method for synthesis of optically pure 4-alkenyl or 4-alkanyl-2-hydroxytetronic acids from an optically pure aldehyde. The invention further relates to the use of such optically pure compounds as potent inhibitors of pla... | 04/02/1996 |
| 5399721 | Synthesis of optically pure 4-aryl-2-hydroxytetronic acids The present invention relates to a method for synthesis of optically pure stereogenically labile 4-aryl-2-hydroxytetronic acids from an optically pure aldehyde. The invention further relates to the use of such optically pure compounds as potent inhibitors... | 03/21/1995 |
| 5359139 | Tertiary amine treatment A tert-amine which contains an acid-activated color body precursor is treated to prevent it or a derivative thereof, e.g., an amine oxide, betaine, or quaternary ammonium compound, from turning pink when exposed to acidic conditions by contacting it with ... | 10/25/1994 |
| 5298526 | Optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids and pharmaceutical use The present invention relates to a method for synthesis of optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids from an asymmetric -hydroxy ester. The chiron approach of the present invention utilizes a non-nucleophilic lithi... | 03/29/1994 |
| 5283258 | Procaine double salt complexes A procaine acid addition salt, wherein the acid is attached to the diethylamino nitrogen, is complexed with a biologically active organic acid such as a vitamin acid, essential unsaturated fatty acid, C4 to C6 hydroxycarboxylic acid ... | 02/01/1994 |
| 5270336 | Ascorbic acid derivatives Derivatives of 3,4-dihydroxy-2,5-dihydrofuran-5-ones, intermediates and processes useful for their preparation are disclosed. These compounds are useful as free-radical scavengers and exhibit cellular protective properties.... | 12/14/1993 |
| 5242945 | Tetronic and thiotetronic acid derivatives as phospholipase A2 inhibitors There are disclosed compounds of the formula: ##STR1## wherein X is --CH2 R; R is ##STR2## and further when Y=S, R may also be --(CH2)e CH3 ; Y is --O--or --S--; R1 and R2 are ea... | 09/07/1993 |
| 5189057 | Saccharoascorbic acid derivatives A compound of the formula (I): ##STR1## wherein R1 and R2 each is a hydrocarbon residue, R3 is a sulfo group or phosphono group, --CO--R4 is an esterified carboxyl group, a thiol-esterified carboxyl group o... | 02/23/1993 |
| 5180839 | Anti-thrombotic compounds P-carboethoxy ammonium ascorbate as an anti-thrombotic compound and method of making same from ascorbic acid and ethyl p-amino benzoate.... | 01/19/1993 |
| 5041563 | Rearrangement process A process for the manufacture of ascorbic acid from 2-ketogulonic acid esters (KGAE) utilizing amine salts of the latter is disclosed.... | 08/20/1991 |
| 4526989 | 1,4-Bis (substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof This disclosure describes symmetrical 1,4-bis (substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.... | 07/02/1985 |
| 4368330 | Derivatives of L-ascorbic acid and D-erythorbic acid 5,6-Anhydro-L-ascorbic acid, 5,6-anhydro-D-erythorbic acid and salts thereof are disclosed. Such compounds are useful intermediates in the preparation of 6-deoxy-6-substituted-L-ascorbic acid and 6-deoxy-6-substituted-D-erythorbic acid, which are useful a... | 01/11/1983 |
| 4329290 | Antithrombotic derivatives of ammonium ascorbate A solution of L-ascorbic acid and a solution of para amino benzoic acid are mixed and the mixture evaporated to permit recovery of a solid compound. The compound is administered to a host to reduce thrombotic tendencies.... | 05/11/1982 |
| 4285964 | Salts of (+)-catechine, their preparation and use, and compositions containing these salts A salt of (+)-catechin formed of the reaction product of (+)-catechin with at least a basic amino-acid, such as L-lysine and L-arginine; a hydrosoluble double salt is formed by the reaction product of (+)-catechin with a basic amino-acid, such as L-lysine... | 08/25/1981 |
| 4246201 | Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines possessing pharmacological activity Compound of formula: ##STR1## wherein R represents hydrogen or an alkyl group having from 1 to 4 carbon atoms; R', R", R'" and R"", equal or different from each other represent hydrogen atoms or OH groups, with the limitation that when R', R", R'" an... | 01/20/1981 |
| 4164585 | Anti-thrombotic compound and method of making and using the same for pharmaceutical purposes A solution of L-ascorbic acid and a solution of para amino benzoic acid are mixed and the mixture evaporated to permit recovery of a solid compound. The compound is adminstered to a host to reduce thrombotic tendencies.... | 08/14/1979 |
| 4097428 | Fortimicin C and process for production thereof A new antibiotic, Fortimicin C, is produced by fermentation of a microorganism belonging to the genus Micromonospora. The antibiotic is accumulated in the culture medium and is isolated therefrom.... | 06/27/1978 |
| 4029676 | Esters of tetrahydronaphthyloxy-aminopropanols Compounds having the formula ##STR1## wherein R1 is lower alkyl; R3, R4, R5, R6, and R7 are the same or different and are hydrogen or lower alkyl; R8, R9, and R | 06/14/1977 |
| 4005109 | Preparation of prostaglandin intermediates Preparation of prostaglandin intermediates by reacting mon-tetrahydropyranyl ether, in a diethyl ether medium containing pyridine, with malonyl dichloride, reacting the resulting malonic acid chloride with triethylamine in a diethyl ether medium to produc... | 01/25/1977 |
| 3989722 | 1-Aminomethyl-2,2-diaryl-cyclopropane carboxamides The invention relates to 1-aminomethyl-2,2-diaryl cyclopropane carboxamides of the general formula ##SPC1## In which R represents the hydrogen atom, a halogen atom or a lower alkyl group or a lower alkoxy group; R1 and R2 which may b... | 11/02/1976 |
