Quotables
"The production of too many useful things results in too many useless people."
Karl Marx
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7582779 | Processes and intermediates for the preparations of prostaglandins The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2, R3,... | 09/01/2009 |
| 7439373 | Crystalline mycophenolate sodium Provided are crystalline mycophenolate sodium forms and processes for their preparation. ... | 10/21/2008 |
| 7282596 | Method and intermediate for preparing a prostaglandin F-type compound A method for preparing a prostaglandin F-type compound. Also disclosed is an intermediate of the following formula (II) compound wherein R′, X and A have the same meaning as given in the specification. ... | 10/16/2007 |
| 7276533 | Compositions useful for the treatment of pathologies responding to the activation of PPAR-gamma receptor This invention features the use of the spirolaxine of formula (I) for the treatment of those pathologies responding to the activation of the PPARγ receptor, such as the Type 2 insulin-resistant diabetes. This invention also features a pharmaceutical composition in ... | 10/02/2007 |
| 7271273 | Method for the preparation of citalopram The invention provides a new and improved method for the preparation of 5-cyano-phtalid, which is a key intermediate in the preparation of the antidepressant compound citalopram. ... | 09/18/2007 |
| 7268239 | Process for the preparation of prostaglandins and analogues thereof Disclosed are processes for the synthesis and purification of prostaglandins and analogues thereof, especially analogues of PGF2α. ... | 09/11/2007 |
| RE39755 | 3-(1-hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one a process for the preparation thereof and the use thereof A product corresponding to formula (I) or its ketonic tautomer form (II) which is 3-(1-hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one, a process for the preparation and use of the product corresponding to formula (I) or its tau... | 07/31/2007 |
| 7145020 | Materials and methods for treating coagulation disorders This invention is drawn to compounds which are more easily metabolized by the metabolic drug detoxification systems. Particularly, warfarin analogs which have been designed to include esters within the structure of the compounds are taught. The invention teaches met... | 12/05/2006 |
| 7122687 | Process for the production of an immunosuppressant In one aspect, the present invention provides a process for producing a sodium salt of an immunosupressant of Formula I ... | 10/17/2006 |
| 7109371 | Prostaglandin synthesis A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralk... | 09/19/2006 |
| 7026351 | Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof The present invention provides cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, methods of making cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs and compositions of cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs. The present invention also provides methods o... | 04/11/2006 |
| 6992197 | Lactone compound A novel monomer compound having a lactone moiety of the present invention can be converted into polymers usable as resist materials with excellent properties, etc., and an alcohol compound having a lactone moiety of the invention is useful as a material for the mono... | 01/31/2006 |
| 6911548 | Method for the preparation of 5-cyanophthalide A method for the preparation of 5-cyanophthalide comprising treatment of a compound of formula IV wherein X is O or S; R1-R2 are each independently selected from... | 06/28/2005 |
| 6888009 | Method for the preparation of 5-carboxyphthalide 5-carboxyphthalide is obtained with very high purity and in high yields by a convenient process comprising reaction of terephthalic acid with paraformaldehyde HO(CH2)nH in oleum. ... | 05/03/2005 |
| 6868215 | Dye thin film, production method thereof, optical switch, optical distributor, optical modulator and optical switch array A dye thin film containing a dye compound represented by the general formula (I), an optical switch, an optical distributor, an optical modulator and an optical switch array having the dye thin film, as well as a method for producing a dye thin film are provided. Th... | 03/15/2005 |
| 6864279 | Materials and methods for treating coagulation disorders This invention is drawn to compounds which are more easily metabolized by the metabolic drug detoxification systems. Particularly, warfarin analogs which have been designed to include esters within the structure of the compounds are taught. The invention teaches met... | 03/08/2005 |
| 6825363 | Compounds useful in optical switching and manufacturing method thereof A dibenzofuranonylium methylate compound represented by the following formula (I), having maximum absorption wavelength of over 1 μm, high thermal stability and good solubility in organic solvents, and a production method thereof are provided: | 11/30/2004 |
| 6809208 | 3-Arylbenzofuranones with electron-withdrawing substituents as stabilizers The invention describes novel compounds of the formula (I) wherein the general symbols are as defined in claim (1) and R1 is an aromatic radical with electron withdrawing substituents, as stabilizers for protecting organic materials, in particular polymer... | 10/26/2004 |
| 6780887 | Anti-ischemic compounds The present invention is related to a compound of formula (I), salts and pro-drugs of the compound (I) and methods for treating and/or preventing partial or total ischemia, methods for treating and/or preventing pathologies associated with ischemia or with mitochond... | 08/24/2004 |
| 6762327 | Selective oxidation process with enhanced safety A safe and effective process for the oxidation of a primary or secondary alcohol to the corresponding aldehyde or ketone via the reaction of said alcohol with an anhydride solution of a 1,1,1-tri(C2-C4 alkanoyloxy-1,1-dihydro-1,2-benziodoxol-3(... | 07/13/2004 |
| 6703516 | Process for the preparation of 5-carboxyphthalide There is described a process for the preparation of 5-carboxy phthalide, which comprises adding terephthalic acid to fuming sulfuric acid containing at least 20% of SO3, then adding formaldehyde to the mixture, heating the mixture at a temperat... | 03/09/2004 |
| 6586606 | Process for the preparation of 3-aryl-benzofuran-2-ones The instant invention discloses a process for the preparation of compounds of formula I ##STR1## wherein the general symbols are as defined in claim 1, which process comprises hydrolyzing a compound of formula V ##STR2## wherein the general symbols a... | 07/01/2003 |
| 6515147 | 3-(1-hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one a process for the preparation thereof and the use thereof A product corresponding to formula (I) or its ketonic tautomer form (II) ##STR1## which is 3-(1-hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one, a process for the preparation and use of the product corresponding to formula (I) or its tautomeric form (II)... | 02/04/2003 |
| 6500962 | Production method of -methylene-γ-butyrolactones The present invention relates to a method for producing an -methylene-γ-butyrolactone which is one of basic structures often shown in drugs such as an anti-cancer agent by reacting an alene compound having an aldehyde or ketone group with carbon m... | 12/31/2002 |
| 6482959 | Process for the stereoselective reduction of ,ଲ-unsaturated ketones A process for the preparation of ,ଲ-unsaturated alcohols of general formula (I), ##STR1## wherein R means an alkyl group of 1-4 carbon atoms, or benzoyloxy group optionally substituted with a phenyl group; R1 means a hydrogen atom ... | 11/19/2002 |
| 6462074 | Substituted , ଲ-anellated butyrolactones The present invention relates to novel substituted (,ଲ-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in... | 10/08/2002 |
| 6458973 | Process for the preparation of 5-carboxyphthalide There is described a process for the preparation of 5-carboxy phthalide, which comprises adding terephthalic acid to fuming sulfuric acid containing at least 20% of SO3, then adding formaldehyde to the mixture, heating the mixture at a temperat... | 10/01/2002 |
| 6429203 | Farnesyl-protein transferase inhibitors Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described... | 08/06/2002 |
| 6403813 | Method for the preparation of 5-carboxyphthalide 5-carboxyphthalide is obtained with very high purity and in high yields by a convenient process comprising reaction of terephthalic acid ##STR1## with paraformaldehyde HO(CH2)n H in oleum.... | 06/11/2002 |
| 6376539 | Substituted bicyclic lactones The present invention relates to novel substituted bicyclic lactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cereb... | 04/23/2002 |
| 6376535 | Oxygen-containing heterocyclic compounds The present invention relates to oxygen-containing heterocyclic compounds represented by the following formula (I): ##STR1## wherein m represents an integer of 0 to 4; R1, R2, R3 and R4 independently represent a... | 04/23/2002 |
| 6268394 | Farnesyl-protein transferase inhibitors Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described... | 07/31/2001 |
| 6207841 | Bisphenol derivative and its manufacturing method A bisphenol derivative represented by the following formula and a manufacturing method thereof are disclosed. ##STR1## where R is a lower alkyl group, tetrahydropyranyl, methoxymethyl or trialkylsilyl group, and the benzene rings in the formula may be ... | 03/27/2001 |
| 6153645 | Heterocycles as antimicrobial agents Methods for treating infection and related compositions, compounds of formula I as defined in the application and methods for preparing same, are provided. In general, the compounds inhibit transfer ribonucleic acid (tRNA) synthetase and are useful as ant... | 11/28/2000 |
| 6100292 | Ketone derivatives and their medical applications This invention relates to ketones represented by the following formula ##STR1## and to drugs in which such a ketone or pharmacologically acceptable salt thereof is an effective component. The ketones of the present invention encourage the production of pl... | 08/08/2000 |
| 6051565 | Farnesyl-protein transferase inhibitors Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described... | 04/18/2000 |
| 6048882 | Prophylactic and therapeutic agent for hepatic diseases Hepatic diseases can be prevented or treated by administering an isoprenylamine derivative represented by the general formula (II) ##STR1## [wherein n represents an integer of 4-12, m represents an integer of 0-3, Ar represents a phenyl group, a fury... | 04/11/2000 |
| 6028204 | Process for preparing phthalides The disclosure is a process for preparing a phthalide of the general formula I ##STR1## where R1, R2, R3 and R4 are each independently of the others hydrogen, C1 -C4 -alkyl or C1 | 02/22/2000 |
| 6020501 | Process for preparing phthalides The disclosure is a process for preparing a phthalide of the general formula I ##STR1## where R1, R2, R3 and R4 are each independently of the others hydrogen, C1 -C4 -alkyl or C1 | 02/01/2000 |
| 5900492 | Method of producing optically active cyclopropane derivatives A method for resolving optically impure 3-oxa-2-oxobicyclo3.1.0!hexane-1-carboxylic acid esters. A method is provided for producing a 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid.N-benzyl--phenylethylamine diastereomer salt... | 05/04/1999 |
