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| Number | Title | Issue Date |
| 8008510 | Metalloprotein inhibitors The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherei... | 08/30/2011 |
| 7473790 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1 and R2, are as defined herein. The invention a... | 01/06/2009 |
| 7022842 | Process for synthesizing beta-lactam It is an object of the present invention to provide a method for synthesizing β-lactams and a method for manufacturing β-lactams in water of high-temperature and under high-pressure, and the present invention relates to a β-lactam synthesis method which is charac... | 04/04/2006 |
| 6509299 | Pyrone compounds and there use A pyrone compound given by formula (1) ##STR1## wherein R represents a trifluoromethyl group, hydrogen atom or methyl group, has an excellent effect for controlling harmful pests.... | 01/21/2003 |
| 6509298 | Arthropod-controlling composition 4-Hydroxy-6-methyl-3-(3-methylbutanoyl)-2-pyrone has a rapid controlling effect against arthropods such as Dictyoptera insects (e.g. German cockroach, smokybrown cockroach).... | 01/21/2003 |
| 6414122 | Bifunctional boronic compound complexing reagents and complexes Embodiments include reagents to modify a bioactive species for incorporating a bifunctional boronic compound complexing moiety for subsequent conjugation to a different or same bioactive species having pendant phenylboronic acid moieties of General Formul... | 07/02/2002 |
| 6340739 | Polyamide and process for producing the same A polyamide having repeating units represented by formula (1), wherein R1 represents a divalent hydrocarbon residue optionally having in the structure a heteroatom having no active hydrogen. The polyamide has a high refractive index, is biodegr... | 01/22/2002 |
| 6271180 | Substituted phenyl keto enols as pesticides and herbicides The present invention relates to novel compounds of the formula (I) ##STR1## in which Het represents one of the groups ##STR2## in which A, B, D, G, V, W, X, Y and Z are as defined in the description, processes and intermediates for their preparation, and... | 08/07/2001 |
| 6239291 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 05/29/2001 |
| 6228882 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 05/08/2001 |
| 6191288 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 02/20/2001 |
| 6184393 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 02/06/2001 |
| 6127551 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 10/03/2000 |
| 6100292 | Ketone derivatives and their medical applications This invention relates to ketones represented by the following formula ##STR1## and to drugs in which such a ketone or pharmacologically acceptable salt thereof is an effective component. The ketones of the present invention encourage the production of pl... | 08/08/2000 |
| 6096740 | Dexanabinol derivatives and their use as neuroprotective pharmaceutical compositions The present invention relates to pharmaceutical compositions for preventing or alleviating neurotoxicity. Said pharmaceutical compositions comprise as their active ingredient the stereospecific (+) enantiomers, having (3S,4S) configuration, of Ɗ6 | 08/01/2000 |
| 6090953 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 07/18/2000 |
| 6022983 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 02/08/2000 |
| 6020502 | Preparation of fluorinated dicarbonyls A method for the fluorination of 1,3-diketones and 1,3-ketoesters is disclosed.... | 02/01/2000 |
| 5986111 | Pyronin antibacterials, process and novel intermediates thereto The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of py... | 11/16/1999 |
| 5977029 | 3-aryl-5-halogen-pyrone derivatives as pest control agents The invention relates to novel 3-aryl-5-halogeno-pyrone derivatives of the formula (I) ##STR1## in which A, D, G, X, Y, Z and n are each as defined in the description, to a plurality of processes and intermediates for their preparation and to their u... | 11/02/1999 |
| 5972237 | Use of heterocyclic compounds as activators for inorganic peroxy compounds Heterocyclic compounds I R1 --X--L (I) where L is a cyclic carbamate residue, a lactonoxy residue or a lactam residue, X is an oxygen-containing group ##STR1## where A is a linker, and R1 is an ... | 10/26/1999 |
| 5905090 | Analogues of the active metabolite of leflunomide Analogues of the active metabolite of leflunomide, and to the use thereof as immunosuppressive and/or antinflammatory agents.... | 05/18/1999 |
| 5808062 | Pyrone derivatives as protease inhibitors and antiviral agents The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment ... | 09/15/1998 |
| 5670662 | Pyranones A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centres which comprises selective reaction of at least one isomer with a reagent catalysed by a hydrolase enzyme whereby a... | 09/23/1997 |
| 5527916 | Pyranones A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centers which comprises selective reaction of at least one isomer with a reagent catalyzed by a hydrolase enzyme whereby a... | 06/18/1996 |
| 5443971 | Pyranones A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centers which comprises selective reaction of at least one isomer with a reagent catalyzed by a hydrolase enzyme whereby a... | 08/22/1995 |
| 5443970 | Pyranones A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centres, which comprises selective reaction of at least one isomer with a reagent catalysed by a hydrolase enzyme whereby ... | 08/22/1995 |
| 5412110 | Enzymatic process to separate racemic mixtures of delta valerolactones Process to separate racemic mixtures of beta-hydroxy or beta-acyloxy-delta-valerolactones, which in position 2 and/or 5 of the lactone ring are substituted by hydrogen, alkyl groups having 4 to 20 C atoms, which are optionally penetrated by an oxygen atom... | 05/02/1995 |
| 5393729 | 3-aryl-pyrone derivatives The invention relates to 3-aryl-pyrone derivatives of the general formula (I) ##STR1## in which the substituents are as defined in the specification. The compounds are useful as pesticides, herbicides and fungicides.... | 02/28/1995 |
| 5387689 | Chiral valerolactone derivatives The invention relates to chiral valerolactone derivatives of the formula I ##STR1## wherein R1 is C1-18 alkyl in which one or two non-adjacent --CH2 groups are optionally replaced by --O--, --CO--O--, --O--CO-- or --S... | 02/07/1995 |
| 5296613 | Pyran derivatives Compounds of formula I: ##STR1## wherein: R1 is hydrogen or alkyl; R2 is alkyl optionally substituted by one or more alkoxy groups or halogen atoms; X is a group of formula --OR3 wherein R3 is alkyl, cycloalkyl, or arylalkyl; or X is a group of formu... | 03/22/1994 |
| 5260426 | Process for the preparation of pseudo primycin The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to the pharmaceutical compositions containing said c... | 11/09/1993 |
| 5185349 | Substituted amide ACAT inhibitors lactone derivatives Novel lactone and lactam compounds which are useful to lower blood cholesterol levels in a patient, said compounds containing an arylcarboxamide or arylthiocarboxamide moiety.... | 02/09/1993 |
| 5155236 | Pyran derivatives Compounds of formula I: ##STR1## wherein: R1 is hydrogen or alkyl; R2 is alkyl optionally substituted by one or more alkoxy groups or halogen atoms; X is a group of formula --OR3 wherein R3 is alkyl, cycloalkyl, or arylalkyl; or X is a group of formu... | 10/13/1992 |
| 5134231 | 3(1-hydoxyethyl)azetidinone compounds and their production An amino acid compound of the formula: ##STR1## wherein R is a lower alkyl group, R1 is a hydrogen atom or a protecting group for carboxyl, R2 is a hydrogen atom, a protecting group for amino, an optionally substituted allyl gro... | 07/28/1992 |
| 5114461 | Cyclic diones A 2-benzoylcyclic-1,3-dione derivative of the formula: ##STR1## wherein X represents methylene, oxygen, sulphur or --NR4 --, Y represents --C(R5) (R6)-- or oxygen, R1 represents hydrogen or alkyl optionally... | 05/19/1992 |
| 5104857 | Pseudo-primycin complexes, components and acid addition salts thereof The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to the pharmaceutical compositions containing said c... | 04/14/1992 |
| 5062880 | 1-aryl-1,4-dihydro-4-oxo-5-carboxypyridazine derivatives and their use as plant growth regulators and hybridizing agents This invention relates to 1-aryl-1,4-dihydro-4-oxo-5-carboxypyridazine derivatives which are not only useful as plant growth regulators and hybridizing agents for cereal crops but possess the additional utility of having an improved margin of safety as co... | 11/05/1991 |
| 5011944 | Substituted -pyrones -Pyrones of the formula I ##STR1## in which R1 is --CF3 or --COOR3 and R3 is the radical of a C1 -C18 alcohol diminished by a hydroxyl group, and R2 is --F, --Br, --C... | 04/30/1991 |
| 5001255 | Idene analogs of mevalonolactone and derivatives thereof Compounds of the formula ##STR1## the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprisi... | 03/19/1991 |
