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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 7384975 | Substituted furochromenes, preparation thereof and their antiinflammatory action The invention relates to novel compounds of the formula (I) including all their tautomers, to pharmaceutically acceptable salts and solvates thereof, to processes and reactive intermediates for the preparation thereof, and ... | 06/10/2008 |
| 7329654 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders mediated by one or more estrogen receptors and processes for their prepar... | 02/12/2008 |
| 7081475 | Wortmannin analogs and methods of using same Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well as tumor formation in a subject are described herein. ... | 07/25/2006 |
| 6685972 | Process for isolating artemisinin from Artemisia annua The present invention relates to a process for the isolation of artemisinin, an antimalarial agent from the herb of the Artemisia annua plant, comprising of extracting the herb with ethanol, partitioning of the extract between water and hexane, followed b... | 02/03/2004 |
| 6583298 | Process for the synthesis of 17ଲ-hydroxy-17-methyl-2-oxa-5-androstane-3-one The invention relates to a new process for the synthesis of 17ଲ-hydroxy-17-methyl-2-oxa-5-androstane-3-one of formula (I). The process according to the invention is as follows: the 17ଲ-hydroxy-17-ethyl-1,3-seco-2-nor-5�... | 06/24/2003 |
| 6552071 | Methods for treating cell death diseases and inflammation The present invention features methods and compounds for treating or preventing a cell death disease or inflammation, and methods for synthesizing wedelolactone.... | 04/22/2003 |
| 6384045 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxypyrone synthetic method is a simple con... | 05/07/2002 |
| 6303797 | Sesterterpene derivatives exhibiting antifungal activities A compound represented by the formula [I] ##STR1## wherein Y1 represents an oxygen atom, or a group represented by NH, O--CO, O--SO2, O--CO--NH, O--CS--NH, NH--CO, NH--SO2, NH--CO--NH or NH--CS--NH, R1 represent... | 10/16/2001 |
| 6225339 | Terpenoid lactone compounds and their production process This invention provides terpenoid lactone compounds, and processes for producing the terpenoid lactone compounds, which comprise cultivating Oidiodedron griseum FERM BP-5778 and then isolating the terpenoid lactone compounds from the fermentation broth. T... | 05/01/2001 |
| 5958970 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxyprone synthetic method is a simple cond... | 09/28/1999 |
| 5928910 | Antifungal substances BE-49385 and process for their production The present invention relates to a compound represented by the general formula (I): ##STR1## wherein R1 is a hydrogen atom, or ##STR2## and R2 is a hydrogen atom or OH and R2 is a hydrogen atom or a lower al... | 07/27/1999 |
| 5777134 | 4-oxa and 4-thia steriods The novel compounds of the present invention are those of structural formula I: ##STR1## wherein X is selected from O and S, or a pharmaceutically acceptable salt, ester, or stereoisomer thereof, and are inhibitors of 5-reductase. The com... | 07/07/1998 |
| 5310946 | Cyclic peroxyacetal lactone, lactol and ether compounds A process for preparing a compound containing (a) peroxyacetal lactone, (b) peroxyacetal lactol or (c) peroxycacetal ether functionality comprising oxygenating in the presence of one or more oxidizing metal catalysts a compound containing (i) hydroperoxy ... | 05/10/1994 |
| 5225554 | Polyoxa tetracyclic compounds A process for synthesizing polyoxa tetracyclics which involves the ozonolysis of a single-ring-structure vinyl silane with resulting direct formation of the desired multiple ring material. The polyoxa tetracyclic compounds have the formula ##STR1## ... | 07/06/1993 |
| 5180840 | Process for preparing analogs of artemisinin A process for synthesizing oxygen-containing polyoxatetracycle compounds and in particular analogs of the antimalarial agent known as qinghaosu or artemisinin is disclosed. The process employs as a reactant an olefinically unsaturated bicyclic bridging ke... | 01/19/1993 |
| 5019590 | Antimalarial analogs of artemisinin A process for synthesizing oxygen-containing polyoxatetracycle compounds and in particular analogs of the antimalarial agent known as qinghaosu or artemisinin is disclosed. The process employs as a reactant an olefinically unsaturated bicyclic bridging ke... | 05/28/1991 |
| 4963683 | Process for preparing polyoxa tetracyclic compounds A process for synthesizing polyoxa tetracyclics which involves the ozonolysis of a single-ring-structure vinyl silane with resulting direct formation of the desired multiple ring matrial. The polyoxa tetracyclic compounds have the formula ##STR1## ... | 10/16/1990 |
| 4914106 | Compositions and methods employing 2-oxa- or -aza-pregnan compounds for inhibiting androgen or supplying progestin in mammals A compound represented by the following formula ##STR1## wherein A represents a hydrogen atom or a lower alkanoyl group, Z represents an oxygen atom or the group ##STR2## in which R represents a hydrogen atom or a lower alkyl group, and X r... | 04/03/1990 |
| 4785103 | 2-oxa- or -aza-pregnane compounds A compound represented by the following formula ##STR1## wherein A represents a hydrogen atom or a lower alkanoyl group, Z represents an oxygen atom or the group ##STR2## in which R represents a hydrogen atom or a lower alkyl group, and X r... | 11/15/1988 |
| 4740521 | Saudin, a novel hypoglycemic agent Saudin, a novel terpenoid substance having hypoglycemic properties, isolated from the plant Cluytia richardiana L. Euphorbiaceae, and a method for lowering blood sugar by injection thereof into the body.... | 04/26/1988 |
| 4476131 | Substituted hexahydropyrrolo[1,2-a]-quinolines, hexahydro-1H-pyrido[1,2-a]- q Tricyclic benzo fused compounds of the formula ##STR1## and pharmaceutically acceptable cationic and acid addition salts thereof, wherein n is zero, 1 or 2, and t is 1 or 2; M is CH or N, R1 is H or certain acyl groups; Q is CO2... | 10/09/1984 |
| 4147798 | Antineoplastic agent Disclosed herein is a method of culturing Aspergillus terreus strain NRRL 11156 to produce an antineoplastic compound designated as quadrone and having the following structure: ##STR1##... | 04/03/1979 |
