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Class 549/275 - Polycyclo ring system having the lactone ring as one of the cyclos


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the six-membered lactone ring is one of
No. of patents: 27
Last issue date: 03/04/2008


NumberTitleIssue Date
7338720Organic electroluminescent element
An organic electroluminescent (EL) device which uses, as a luminescence-assisting agent, a novel coumarin derivative with a specific structure. The coumarin derivative effectively accelerates in such an organic EL device the transfer of excited energy in a host comp...
03/04/2008
7314942Methylenelactones syntheses in supercritical fluids
Alpha-methylenelactone is produced from butyrolactone and valerolactone by the addition of formaldehyde in a supercritical fluid. ...
01/01/2008
7252892Organic electroluminescence device
An organic electroluminescent (EL) device which contains a novel coumarin derivative composed of a coumarin ring, a naphthalene ring with one or more hydrocarbon groups, and a five-membered hetero ring condensed with the naphthalene ring so as to give an electronic ...
08/07/2007
7153946Molecular conjugates for use in treatment of cancer
A molecular conjugate is provided having the formula: wherein R1 is a de-hydroxyl or de-amino moiety respectively of a hydroxyl-bearing or amino-bearing biologically active molecule or an analog or der...
12/26/2006
7132117Bioactive fraction of
The invention provides new uses and products for treatment of sexual dysfunction and male infertility. The products include bioactive components of extracts from roots of the plant Eurycoma longifolia mixed in preparations for topical application and administ...
11/07/2006
7078386Enhancing agent for nerve growth factor production comprising a compound having a coumarin backbone or a compound having a 2-dimethyl chroman backbone
The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like o...
07/18/2006
6812245Polycylic xanthones and their use
A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated IB-00208. The class of the formulae (I) or (II) where R1
11/02/2004
6383666Organometallic complex and organic electroluminescent device using the same
Disclosed are new organometallic complex molecules having light-emitting and electron-transporting characteristics. Also disclosed is organic EL (electroluminescent) devices using these organometallic complex molecules as electron-transporting materials. ...
05/07/2002
6172241Process for the preparation of 1,2-dihydroquinolines
A method for preparing 1,2-dihydroquinolines that is more flexible than the Skraup reaction is provided. The method comprises treating an ortho-alkenyl aniline with a ketone in the presence of a Lewis acid. Novel intermediates and products of this method ...
01/09/2001
6149841Photochromic benzopyrano-fused naphthopyrans
Described are novel photochromic benzopyrano-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted benzopyran group fused to one side of the naphtho portion of the naphthopyran and having certain ...
11/21/2000
5985913Tetracyclic compounds for enhancing biosynthesis of erythropoietin, compositions containing same, and methods of use thereof
The present invention provides a compound in substantially pure form having the structure: ##STR1## wherein each of R1, R2, R3, R4, R5, R6, R7, and R8 may indepen...
11/16/1999
5965493Therapeutic Quassinoid preparations with antineoplastic, antiviral, and herbistatic activity
The present invention includes purified and isolated quassinoids and synthetically derived quassinoid analogs based on a picrasane carbon skeleton. Novel sidechains at C-15 incorporating water solubilizing agents such as glycine are discussed. Therapeutic...
10/12/1999
5849748Therapeutic quassinoid preparations with antineoplastic antiviral, and herbistatic activity
The present invention includes purified and isolated quassinoids and synthetically derived quassinoid analogs based on a picrasane carbon skeleton. Novel sidechains at C-15 incorporating water solubilizing agents such as glycine are discussed. Therapeutic...
12/15/1998
5652096Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes
Hybridization method for discriminating between complementarity and partial complementarity of DNA base sequences. Kinetic covalent entrapment of PCR-amplified target DNA is achieved through the use of crosslinkable probes. A crosslinking site is introduc...
07/29/1997
5639712Therapeutic quassinoid preparations with antineoplastic, antiviral, and herbistatic activity
Quassinoid compounds, compositions, and methods of using them for treating cells and solid tumors, and inhibiting plant growth. The quassinoid derivatives herein are 11,20-epoxy-1,11,12-trihydroxypicras-3-ene-2,16 diones: ##STR1##...
06/17/1997
5480906Stereochemical Wortmannin derivatives
This invention relates to derivatives of Wortmannin and particularly to 11,17 substituted derivatives of Wortmannin. The invention also relates to a method of using these compounds as PI-3-kinase inhibitors and as anti-tumor agents....
01/02/1996
5468772Tripterinin compound and method
An immunosuppressive compound having the structural formula: ##STR1## is disclosed, along with immunosuppression treatment methods which employ the compound....
11/21/1995
5384078Soluble highly reactive form of calcium and reagents thereof
A soluble highly reactive form of calcium, prepared from Ca(II) salts and a reducing agent in ethereal, polyethereal, or hydrocarbon solvents, is presented. This form of calcium can be used in the preparation of organocalcium reagents. The organocalcium r...
01/24/1995
5270182Antibiotic compounds and their production
The novel compounds of formulas I and II ##STR1## have an antibiotic activity....
12/14/1993
4774342Novel ailanthone derivative
An ailanthone derivative having the general formula: ##STR1## wherein R is a p-alkyl benzoic acid residue having 8 to 21 carbon atoms, a 2-methyl saturated fatty acid residue having 6 to 19 carbon atoms, a 2-methyl-2-unsaturated fatty acid residue ha...
09/27/1988
4740521Saudin, a novel hypoglycemic agent
Saudin, a novel terpenoid substance having hypoglycemic properties, isolated from the plant Cluytia richardiana L. Euphorbiaceae, and a method for lowering blood sugar by injection thereof into the body....
04/26/1988
4731459Novel anti-ulcer agents and quassinoids
Highly effective anti-ulcer agents, i.e. Quassinoids of the following formula: ##STR1## wherein R is hydrogen or hydroxy; X is >C.dbd.CH2, >CH--CH3, or ##STR2## and the 3,4-dotted line indicates the presence or absence of ...
03/15/1988
4665201Ailanthone derivatives
Novel antineoplastic ailanthone derivatives (IIb) represented by the following formula wherein R2 is C5 -C18 ଱,ଲ-unsaturated acyl group and its related compounds are disclosed. ##STR1## Particularly, ...
05/12/1987
4376733Preparation of oxacycloalkenones
Oxacycloalkenones are prepared by reacting a cycloalkenone with a base in the presence of a dioxygen source in a suitable solvent and isolating the desired product. 1-Hydroxy 2-oxa-3-oxo-Ɗ4 steroids are convenient synthetic precursors to 2-oxa...
03/15/1983
4350638Bruceolides
There are provided two synthetic routes to the known potent anti-leukemic quassinoid bruceantin from the more readily available bruceoside-A and -B. Certain of the intermediate compounds produced in the synthetic sequence as well as bruceantin itself have...
09/21/1982
4154745Isobenzofuran route to anthracycloquinones
There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (&#b1;)-7-deoxydaunomycinone and analogs thereof which includes the provision of novel tetrahydronaphthoquino...
05/15/1979
3969369Bruceantin
There is provided a novel simaroubolide derived from Brucea antidysenterica which possesses high and surprising anti-leukemic activity at dosage levels of micrograms per kilogram body weight....
07/13/1976
 
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