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| Number | Title | Issue Date |
| 8143428 | Heteroaryl sulfones and sulfonamides and therapeutic uses thereof Compounds of Formula I: wherein R1, R2, M, Q and n are as defined herein, are useful as antiproliferative agents including, for example, as anticancer agents. ... | 03/27/2012 |
| 7396942 | Dual function UV-absorbers for ophthalmic lens materials Disclosed are UV absorbers that contain a labile functional group capable of initiating free radical polymerization. ... | 07/08/2008 |
| 7381842 | Oxime ester photoinitiators Compounds of the formulae I, II, III, IV and V wherein R1 i.a. is C4-C9cycloalkanoyl, C1-C12alkanoyl, C4-C6alke... | 06/03/2008 |
| 7354957 | Multi-functional thioxanthone photoinitiators Compounds of formula (I): {where n is a number from 1 to 6; R3 is hydrogen, methyl or ethyl; A represents a group of formula —[O(CHR2CHR1)a]y—,—[O(CH2)bCO]y—, or —[O(CH... | 04/08/2008 |
| 7335782 | Thioxanthone derivatives, and their use as cationic photoinitiators Photoinitiator compounds of formula (I): {where: A represents a direct bond or a group of formula —[O(CHR7CHR6)a]y—, —[O(CH2)bCO]y—, or ... | 02/26/2008 |
| 7271162 | Cycloocta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives This invention provides compounds of formula I having the structure wherein: R1 and R2 are H, alkyl, cycloalkyl, alkoxy, halogen, fluorinated alkyl, —CN, —NH—SO2-alkyl, —S... | 09/18/2007 |
| 7271164 | Cyclohepta[b][1,4]diazepino[6,7,1,-hi]indoles and derivatives This invention provides compounds of the formula: wherein R1 and R2 are each, independently, H, alkyl, cycloalkyl, —CH2-cycloalkyl, alkoxy, halogen, fluorinated alkyl, —CN, ... | 09/18/2007 |
| 7271163 | Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives This invention provides compounds of the formulae: wherein: R1 is hydrogen, —C(O)CH3 or alkyl of 1-6 carbon atoms; R2 and R | 09/18/2007 |
| 7230122 | Sulfonium salt photinitiators and use thereof Sulfonium salt photoinitiator compositions, precursors useful in the preparation of such photoinitiators and the use of these photoinitiators in, e.g., UV curable adhesives, UV curable sealants, UV curable coating compositions, such as printing inks and varnishes, a... | 06/12/2007 |
| 7126011 | Process for the preparation of thioxanthones Processes are described for the preparation of thioxanthones (Formula I). A reactant mixture of a 2-chlorothiobenzoyl chloride (Formula II) and an aromatic compound (Formula III) is added to a slurry of a Friedel-Crafts catalyst in an organic Friedel-Crafts solvent.... | 10/24/2006 |
| 7101998 | Fused ring compounds, and their use as cationic photoinitiators Compounds of formula (I): [in which: R1 represents a direct bond, an oxygen atom, a group >CH2, a sulphur atom, a group >C═O, a group —(CH2)2— or a group of formu... | 09/05/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6960668 | Process for the production of substituted thioxanthones A one-step process for the preparation of a substituted thioxanthone, such as carboxymethoxythioxanthone, in high yields and as a single isomer. The substituted aryl compound is reacted with mercaptobenzoic acid or dithiobisbenzoic acid in the presence of sulphuric ... | 11/01/2005 |
| 6949678 | Oxime ester photoinitiators Compounds of the formulae I, II, III, IV and V wherein R1 i.a. is C4-C9cycloalkanoyl, C1-C12alkanoyl, C4-C6alkenoyl, or benzoyl; R2 | 09/27/2005 |
| 6768007 | Substituted 3′,4′-di-O-camphanoyl-(+)-cis-khellactone analogs, compositions thereof, and methods for using thereof 3′,4′-di-O-camphanoyl-(+)-cis-khellactone analogs according to the present invention have been found to have anti-HIV activity. The compounds of the present invention have the following formula: or a pharmaceutically... | 07/27/2004 |
| 6767919 | High specificity anticancer agents A process for producing new anticancer drugs such that the drugs can be administered in a nontoxic, proto-drug form and, subsequent to a time delay which allows for differential concentration in the target cancer or invasive tissues or cells, the non-toxic drug is t... | 07/27/2004 |
| 6693136 | Fluorenes and anthracenes that inhibit P2X3 and P2X2/3 containing receptors Compounds of formula (I) ##STR1## are novel P2X3 and P2X2 /P2X3 containing receptor antagonists and are useful in treating pain, urinary incontinence, and bladder overactivity.... | 02/17/2004 |
| 6686386 | Use of a RAR-γ-specific agonist ligand for increasing the rate of apoptosis The present invention relates to pharmaceutical and cosmetic compositions comprising at least one agonist ligand, which is specific for receptors of the RAR-γ type, which are characterized as inducers of apoptosis in at least one cell population in which... | 02/03/2004 |
| 6613797 | Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins Therapeutic compounds and compositions for the treatment of infectious diseases are disclosed. The compounds are xanthones and xanthone derivatives, such as 3,5-bis-&3xb5;-(N,N-diethylamino)amyloxyxanthone. The described compositions include such compound... | 09/02/2003 |
| 6566521 | Valeraldehyde and process for its preparation Bidentate phosphine ligands of the formula ##STR1## wherein the substituents are as defined in the specification and a process for preparing linear aldehydes by hydroformylating internal olefins using such phosphine ligands.... | 05/20/2003 |
| 6420130 | Optical molecular sensors for cytochrome P450 activity The invention provides a compound, useful as an optical probe or sensor of the activity of at least one cytochrome P450 enzyme, and methods of using the compound to screen candidate drugs, and candidate drugs identified by these methods. The optical probe... | 07/16/2002 |
| 6384045 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxypyrone synthetic method is a simple con... | 05/07/2002 |
| 6342605 | Valeraldehyde and process for its preparation Bidentate phosphine ligands of the formula ##STR1## wherein the substituents are as defined in the specification and a process for preparing linear aldehydes by hydroformylating internal olefins using such phosphine ligands.... | 01/29/2002 |
| 6331640 | Diaminopropionic acid derivatives A compound of formula 1a ##STR1## which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.... | 12/18/2001 |
| 6294677 | Thiopyran derivatives An intermediate represented by the following formula (XVIII), ##STR1## wherein A is a sulfur atom or the group --CH.dbd.CH--; L is an alkylene group which may be substituted, an alkenylene group which may be substituted, or an alkynylene group which may b... | 09/25/2001 |
| 6252090 | Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##... | 06/26/2001 |
| 6172058 | Compounds with pharmaceutical properties A pharmaceutical compound of the formula ##STR1## in which R1 is C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 cycloalkyl, C3-10 cycloalkyl-C1-10 alkyl, C3-10 cyclo... | 01/09/2001 |
| 6150536 | Dye doped organic-inorganic hybrid materials The present invention relates to an organic-inorganic hybrid material comprising an organic component and an inorganic component. The organic component comprises a dye that fluoresces in the visible range. In addition, an optically inert component may rep... | 11/21/2000 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 6031014 | Initiator compositions and methods for their synthesis and use Cationic polymerization initiators of formula ##STR1## are disclosed. The acyl sulfonium salts of the present invention differ from known acyl sulfonium initiators in that the substituents R2 and R3 on the sulfur are larger and ... | 02/29/2000 |
| 6025408 | Liquid thioxanthone photoinitiators Novel thioxanthone derivatives and mixtures thereof and methods of making and using the same are disclosed. The novel thioxanthone derivatives can be liquid at room temperature and display highly active photoinitiation and photopolymerization properties.... | 02/15/2000 |
| 5998613 | 4-aminotetrahydrobenzisoxazole or -isothiazole compounds The present invention relates to novel 4-aminotetrahydrobenzisoxazoles or 4-aminotetrahydrobenziothiazoles having gamma-aminobutanoic acid (GABA)-uptake inhibiting activity and thus useful in the treatment of analgesia, psychosis, convulsions, anxiety, ep... | 12/07/1999 |
| 5990104 | Polycyclic alcaloid-derivatives as NMDA-receptor antagonists Polycyclic alkaloids of formula (I), wherein R1 is H, C1-6 alkyl, or C6-12 aryl optionally substituted with polar groups; R2 and R3 are independently H, OH, C1-6 alkyl, --C(NH)--NH2, ... | 11/23/1999 |
| 5985799 | Tricyclic herbicidal heterocycles Compounds of Formula (I), and their N-oxides and agriculturally-suitable salts, are disclosed which are useful in controlling undesired vegetation, wherein J is Formula (II), Q is represented by Q-1 through Q-4 and X, Y, Z, R1-19, m, n, p, q, a... | 11/16/1999 |
| 5958970 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxyprone synthetic method is a simple cond... | 09/28/1999 |
| 5916984 | Process for preparing thioxanthone and derivatives thereof A process for preparing thioxanthone and derivatives thereof is disclosed. In the process, an aromatic compound, such as cumene, is reacted with thiosalicylic acid (TSA) or dithiosalicylic acid (DTSA) in the presence of sulfuric acid. The reaction mixture... | 06/29/1999 |
| 5907046 | Processes for preparing thioxanthone and derivatives thereof A process for preparing thioxanthone and derivatives thereof is disclosed. In the process, an aromatic compound, such as cumene, is reacted with thiosalicylic acid (TSA) or dithiosalicylic acid (DTSA) in the presence of sulfuric acid. The reaction mixture... | 05/25/1999 |
| 5726208 | Heterocyclic tertiary amines New compounds of formula: ##STR1## wherein: --A--D--E, X, n, Y and Z are as defined in the description, in racemic form and in the form of optical isomers, and their addition salts with pharmaceutically acceptable acids. Those compounds may be used as med... | 03/10/1998 |
| 5712401 | Processes for preparing thioxanthone and derivatives thereof A process for preparing thioxanthone and derivatives thereof is disclosed. In the process, an aromatic compound, such as cumene, is reacted with thiosalicylic acid (TSA) or dithiosalicylic acid (DTSA) in the presence of sulfuric acid. The reaction mixture... | 01/27/1998 |
| 5645768 | Photochromic compounds A photochromic compound, in particular, for tinting optical elements made of a plastic material has reduced mobility in plastic material. The photochromic compound is a photochromic 2H-pyran and is distinguished by the aromatic residues being chemically r... | 07/08/1997 |
