Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8178701 | Glycerol levulinate ketals and their use The present disclosure relates to the preparation of ketal compounds from glycerol and levulinic acid and esters, and uses thereof. ... | 05/15/2012 |
| 8071793 | Macrolide compound Disclosed are: a novel dinoflagellate alga; and a macrolide compound which can be used as a novel anticancer agent. Specifically disclosed is a macrolide compound produced by a dinoflagellate Amphidinium sp. Strain HYA002 or HYA0024. The macrolide comp... | 12/06/2011 |
| 7358275 | Internal 1,15-lactones of fluprostenol and related prostaglandin F2a analogs and their use in the treatment of glaucoma and intraocular hypertension Novel derivatives of prostaglandin compounds of the F-series (PGF), specifically macrocyclic internal 1,15-lactones of fluprostenol and related PGF analogs, such as cloprostenol or latanoprost. The novel analogs can be formulated into ophthalmic solutions and topica... | 04/15/2008 |
| 7329703 | Polymerized macrocyclic oligomer nanocomposite compositions The invention relates to polymers derived from macrocyclic oligomers containing organo clay fillers comprising a) a polymer derived from a macrocyclic oligomer; b) clay platelets; and c) the residue of one or more onium compounds having at least one ligand with a C | 02/12/2008 |
| RE39991 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation A compound having the following formula: wherein R3 and M are defined herein, and processes therewith. ... | 01/01/2008 |
| 7309756 | Methods for converting linear polyesters to macrocyclic oligoester compositions and macrocyclic oligoesters Macrocyclic oligoesters and compositions comprising macrocyclic oligoesters are prepared from intermediate molecular weight polyesters. In one embodiment, a diol is contacted with a dicarboxylic acid or a dicarboxylate in the presence of a catalyst to produce a comp... | 12/18/2007 |
| 7265229 | Method for synthesizing macrosphelides The present invention is a method for synthesizing macrosphelides represented by the following formula, and relates to the following method. The hydroxyl group of methyl 3-hydroxybutyrate is protected and reduced to alcohol. The alcohol is then oxidized to give 3-(t... | 09/04/2007 |
| 7256286 | Bryostatin analogues, synthetic methods and uses Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same. ... | 08/14/2007 |
| 7247754 | Method for the production of trimeric ketone peroxide solutions Cyclohexane is reacted with hydrogen peroxide in the presence of nitric acid which is used as a catalyst in a suitable solvent for the production of trimeric cyclohexane peroxide. ... | 07/24/2007 |
| 7241804 | Compositions and methods for modulating apoptosis in cells over-expressing Bcl-2 family member proteins The present invention provides agents and compositions for modulating the apoptotic state of a cell. The agents comprise derivatives of antimycins which bind to an anti-apoptotic Bcl-2 family member protein. Further, the agents preferentially induce apoptosis in cel... | 07/10/2007 |
| 7153438 | Water treatment compositions with masking agent A composition for disinfecting contaminated drinking water. The composition can include a disinfecting agent for disinfecting or sanitizing the water and a masking agent for masking or minimizing undesired characteristics of the disinfecting agent, such as taste and... | 12/26/2006 |
| 7151143 | Blends containing macrocyclic polyester oligomer and high molecular weight polymer The invention provides blends of macrocyclic polyester oligomer (MPO) with high-molecular-weight polymer and polymerization catalyst as friable, one-component, ready-to-polymerize materials with long shelf life. The invention also provides methods for preparation an... | 12/19/2006 |
| 7138531 | Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity Novel carbohydrate-based compounds with an attached ring system that have antimicrobial or cytostatic activity. The compounds are administered to humans and animals for the treatment or amelioration of bacterial, fungal, viral or protozoal infections or tumors. The ... | 11/21/2006 |
| 7135541 | Polyester process using a pipe reactor There are disclosed polyester processes using a pipe reactor and corresponding apparatuses. In particular, there are disclosed processes and corresponding apparatuses including an esterification pipe reactor operated in an upflow or downflow mode, especially in a re... | 11/14/2006 |
| 7115756 | Biologically active lasonolide compounds The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other ... | 10/03/2006 |
| 7105268 | Polymer for photoresist and resin compositions therefor A polymeric compound for photoresist of the invention includes at least one monomer unit represented by following Formula (I): wherein R1, R2, R3, R4 and R5 ... | 09/12/2006 |
| 7101912 | Carbidopa prodrugs and derivatives, and compositions and uses thereof Prodrugs of carbidopa, derivatives of carbidopa prodrugs, methods of making prodrugs of carbidopa and derivatives thereof, methods of using prodrugs of carbidopa and derivatives thereof, and compositions of prodrugs of carbidopa and derivatives thereof are disclosed... | 09/05/2006 |
| 7071291 | Isolation, formulation and shaping of macrocyclic oligoesters Processes for isolating, formulating, and shaping macrocyclic oligesters were developed which allow efficient production of macrocyclic oligoesters substantially free from solvent, which may include additives, fillers, and catalysts. ... | 07/04/2006 |
| 7022806 | Methods for converting linear polyesters to macrocyclic oligoester compositions and macrocyclic oligoesters Macrocyclic oligoesters and compositions comprising macrocyclic oligoesters are prepared from intermediate molecular weight polyesters. In one embodiment, a diol is contacted with a dicarboxylic acid or a dicarboxylate in the presence of a catalyst to produce a comp... | 04/04/2006 |
| 6994914 | Macrocyclic polyester oligomers and processes for polymerizing the same A water slurry process is used to prepare a prepreg and to manufacture articles from macrocyclic polyester oligomers. In one embodiment, a process for preparing a water suspension of macrocyclic polyester oligomers includes the steps of contacting a macrocyclic poly... | 02/07/2006 |
| 6962968 | Purification of macrocyclic oligoesters Acid impurities, such as carboxylic acid-terminated polymers, are removed from macrocyclic oligoesters with ion exchange resins, resulting in macrocyclic oligoesters that are substantially free of acid impurities. The ion exchange resins can be regenerated anew and ... | 11/08/2005 |
| 6960626 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler The invention provides intimate physical mixtures of macrocyclic polyester oligomer (MPO) and filler, as well as methods for their preparation and use. Improved dispersion of filler in a polymer matrix is achieved upon polymerization, and larger amounts of filler wi... | 11/01/2005 |
| 6936723 | Synthetic salicylihalamides, apicularens and derivatives thereof The present invention provides compounds having improved stability over that of natural benzolactones, and a process for synthesizing these compounds. These compounds exhibit anti-cancer activity and inhibit V-ATPase activity. ... | 08/30/2005 |
| 6914109 | Process for the preparation of 15-pentadecanolide The invention relates to a process for the preparation of 15-pentadecanolide by hydrogenating 15-pentadecenolide and to its use. ... | 07/05/2005 |
| 6906188 | Method for synthesizing epothilones and epothilone analogs A method for making epothilones and epothilone analogs is described, as are novel compounds made by the method. Exemplary novel compounds include those according to the formula: With respect the formula, G is selected ... | 06/14/2005 |
| 6906147 | Catalytic systems This invention relates to single-component and multi-component catalytic systems using aryl titanates. Aryl titanate compounds are useful as catalysts and co-catalysts in single-component and multi-component catalytic systems (e.g., for the polymerization of macrocy... | 06/14/2005 |
| 6900339 | Bryostatin composition and bryostatin acquisition methodologies Methods for obtaining bryostatins from the marine bryozoans of the Bugula neritina species complex are provided wherein the methods involve the extraction and purification of bryostatins from the larvae of Bugula neritina organisms. Further, the presen... | 05/31/2005 |
| 6887869 | Mikanolide derivatives, their preparation and therapeutic uses The invention concerns novel mikanolide derivatives, their preparation method and their therapeutic uses, in particular as anti-cancer and anti-viral agents. The compounds correspond to general formula (1) corresponding to general sub-formulae (I)1 and (I... | 05/03/2005 |
| 6861538 | Process for the preparation of cyclic lactic acid oligomer The object of the present invention is to provide a novel method for effectively producing a cyclic lactic acid oligomer, and a cyclic lactic acid oligomer produced by the method. According to the present invention, there is provided a method for producing a cyclic ... | 03/01/2005 |
| 6815463 | Laulimalide derivatives Laulimalide compounds, intermediates thereto and methods for their preparation, and methods for their use in the treatment of diseases characterized by cellular hyperproliferation. ... | 11/09/2004 |
| 6706740 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation Heterocyclic aromatic amides (HAA) according to Formula I: wherein X1-X4, M, Z, and A are herein defined. The invention also encompasses hydrates, salts and complexes thereof. These compounds are us... | 03/16/2004 |
| 6693204 | Method for purification of cyclic ester A method of refining a crystal of a crude cyclic ester comprises the steps of supplying the crude cyclic ester to a vertically extending cylindrical refiner (1) from an inlet (3) provided at a lower part of the refiner (1), agitating the crude cyclic este... | 02/17/2004 |
| 6670389 | Laulimalide derivatives Laulimalide compounds, intermediates thereto and methods for their preparation, and methods for their use in the treatment of diseases characterized by cellular hyperproliferation. ##STR1##... | 12/30/2003 |
| 6646134 | Manufacture of cyclic ester oligomers Cyclic ester oligomers (CEOs) are manufactured from linear polyesters or their precursors by a continuous reactive extraction in which the linear polyesters are converted to the CEOs and the CEOs selectively removed from the mixture by extraction with a f... | 11/11/2003 |
| 6624189 | Byrostatin analogues, synthetic methods and uses Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or imroved recognition domains are disclosed, including methods of preparing and utilizing the same.... | 09/23/2003 |
| 6617304 | Method for producing macrocyclic lactone The invention discloses a method for the production of a macrocyclic lactone represented by a formula (2), which comprises subjecting a hydroxycarboxylic acid ester represented by a formula (1) to intramolecular esterification reaction. ##STR1## In t... | 09/09/2003 |
| 6617348 | Synthetic salicylihalamides, apicularens and derivatives thereof The present invention provides compounds having improved stability over that of natural benzolactones, and a process for synthesizing these compounds. These compounds exhibit anti-cancer activity and inhibit V-ATPase activity.... | 09/09/2003 |
| 6610736 | 16-Halogen-epothilone derivatives, method for producing them and their pharmaceutical use The invention relates to novel epothilone derivatives of general formula (I), wherein R8 means a halogen atom, especially a fluorine or chlorine atom, and the remaining substituents have the meanings given in the description. The novel compound... | 08/26/2003 |
| 6590048 | Highly active cationic ruthenium and osmium complexes for olefin metathesis reactions The present invention describes the use of cationic vinylidene, allenylidene and higher cumulenylidene complexes of ruthenium or osmium as catalysts or catalyst precursors for olefin metathesis reactions of all types, as well as to new cationic allenylide... | 07/08/2003 |
| 6576774 | Process for recycling polytrimethylene terephthalate cyclic dimer This invention is an improvement upon the known process for polymerization of polytrimethylene terephthalate by esterification of terephthalic acid or dimethyl terephthalate with 1,3-propane diol, precondensation of the esterification product to produce a... | 06/10/2003 |
