Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 7193103 | Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using oxazolidinone derivatives Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester by treating N-(3,3-dimethylbutyl)-L-aspartic acid with ketones to give oxazolidinone derivatives, which are condensed with L-phenylalanine methyl ester. ... | 03/20/2007 |
| 7137401 | Drag reduction using maleated fatty acids Non-polymeric drag reducing agents in the form of maleated fatty acids and the esters thereof and the organic, inorganic or amine salts thereof are described herein. These additives are useful to reduce drag in hydrocarbon fluids and multi-phase fluids of hydrocarbo... | 11/21/2006 |
| 7119197 | Method for preparation of (s)-(+)-and(r)-(-)10,11-dihydro-10-hydrodoxy-5h-dibenz/b,f/azephine-5-carboxamide An efficient and high-yielding method for the preparation of optically pure (S)-(+) -10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide and (R)-(−)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide by resolution of racemic (±)-10,11-dihydro-1... | 10/10/2006 |
| 6630596 | Composition and emulsifier The invention relates to an adduct of polyalk(en)yl succinic anhydride and a compound of formula (I): wherein R1 is hydrogen, hydroxyl, hydrocarbyl, hydroxyhydrocarbyl, carbamyl, 1-acetyl, amino, or nitro; R2 is hydrogen, hydroxyl, h... | 10/07/2003 |
| 6130257 | Compositions of enantiomeric diacyl tartaric anhydrides and preparation thereof The present invention relates to compositions comprising mixtures of two enantiomeric forms of diacyl tartaric anhydride and mixtures obtainable by reacting an organic compound with a mixture comprising two enantiomeric forms of diacyl tartaric anhydride.... | 10/10/2000 |
| 6077962 | N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) - L-aspartyl)-L- phenylalanine 1-methyl ester therefrom This invention relates to the chemical synthesis of N-[N-(3,3-dimethylbutyl)-L--aspartyl]-L-phenylalanine 1-methyl ester using peptide coupling methods. The coupling reaction is conducted by condensation of an activated derivative of novel N-neohex... | 06/20/2000 |
| 5696282 | Process for producing organosulfur compounds A process comprises contacting, in the presence of a catalyst, hydrogen sulfide or a mercaptan such as, for example, n-dodecyl mercaptan with an ,ଲ-unsaturated carbonyl or ,ଲ-unsaturated cyano compound such as, for example, methy... | 12/09/1997 |
| 5623079 | Method of preparing N-formyl-L-aspartic anhydride The present invention provides an industrial method of producing N-formyl-L-aspartic anhydride from N-formyl-L-aspartic acid, formic acid and acetic anhydride with less residual formic acid than conventional methods.... | 04/22/1997 |
| 5580995 | Process for preparing anhydride-functional monomers Anhydride-functional polymerizable monomers having the structure: ##STR1## and polymers and reactive compositions prepared from these monomers are disclosed. The reactive compositions are especially useful in primer and clearcoat/basecoat application... | 12/03/1996 |
| 5451687 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid An industrial process for producing O,O'-diacyltartaric anhydride with high purity and high efficiency is disclosed. According to the process of the invention, a carboxylic acid of the formula (I): R1 COOH ... | 09/19/1995 |
| 5430162 | 7-(substituted)-8-(substituted)-9-substituted amino)-6-demethyl-6-deoxytetracyclines The invention provides compounds of formula ##STR1## wherein X, R and R1 are defined in the specification. These compounds are useful as antibiotic agents.... | 07/04/1995 |
| 5399748 | Derivatives of aspartic acid and glutamic acid having anticholecystokinin activity Arylsulfonamide derivatives of -amino dicarboxylic acids such as aspartic acid and glutamic acid posses anti-cholecystokinin activity. They are useful in the treatment of cholecystokinin-related disorders such as anorexia nervosa, pancreatic inflam... | 03/21/1995 |
| 5364945 | Anhydride-functional monomers and polymers and reactive compositions prepared from same Anhydride-functional polymerizable monomers having the structure: ##STR1## and polymers and reactive compositions prepared from these monomers are disclosed. The reactive compositions are especially useful in primer and clearcoat/basecoat application... | 11/15/1994 |
| 5306809 | Acid-labile linker molecules This invention relates to the field of immune therapy of cancer, more specifically to immunoconjugates of a cytotoxic moiety with a targeting moiety, more specifically to immunoconjugates of antibodies or fragments or functional derivatives of antibodies ... | 04/26/1994 |
| 5292480 | Acid-anhydride esters as oil field corrosion inhibitors A corrosion inhibitor with excellent film forming and film persistency characteristics may be produced by first reacting C18 unsaturated fatty acids with maleic anhydride or fumaric acid to produce the fatty acid Diels-Alder adduct or the fatty... | 03/08/1994 |
| 5206392 | Facile synthesis of arylmaleic acids and anhydrides A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonit... | 04/27/1993 |
| 5069818 | Functionalized polyphenylene ethers and blends with polyamides Functionalized polyphenylene ether compositions are provided which are particularly useful for effecting compatibility for a blend of polyphenylene ether resin and a polyamide resin. The functionalized-polyphenylene ether is the reaction product of a ... | 12/03/1991 |
| 5061799 | Preparation of tetraazaindenes A multi-step process for the preparation of tetraazaindenes provides new, intermediate compounds and methods for their formation. A first method or step (1) of the process comprises reacting Meldrum's acid (cyclic dimethylmethylene malonate) or a related ... | 10/29/1991 |
| 5003085 | Acid anhydrides and dianhydrides of disubstituted maleic anhydrides A process is disclosed for preparation of anhydrides containing additional carboxylic acid moieties and dianhydrides of disubstituted maleic anhydride compounds wherein the acid anhydrides and dianhydrides retain their alkene character. The resulting alke... | 03/26/1991 |
| 4996316 | Process for the preparation of tertiary N, N-dimethylamines A process for the preparation of tertiary N,N-dimethylamines by the reaction of primary amines, formaldehyde, and hydrogen under pressure and at elevated temperature in the presence of a nickel-containing hydrogenation catalyst in the liquid phase. The hy... | 02/26/1991 |
| 4965372 | Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates Process and intermediates for isopropyl 3S-amino-4-cyclohexyl-2R-hydroxybutyrate and 3S-amino-2R-hydroxy-5-methylhexanoate from R-malic acid. These products are of known utility in the synthesis of certain renin inhibitors.... | 10/23/1990 |
| 4945172 | Preparation of N-formyl-L-aspartic anhydride N-formyl-L-aspartic anhydride is prepared using a minimum excess of formic acid. Acetic anhydride and a C3 -C6 secondary alcohol are added to the reaction mixture to consume excess formic acid. The reaction is suitable for further re... | 07/31/1990 |
| 4931572 | Aromatic carboxylic anhydride catalyst In accordance with the process of this invention, an improved titanium dioxide rutile-based catalyst for molecular oxidation of a hydrocarbon to form the corresponding carboxylic anhydrides is prepared by the steps of (a) forming a catalyst precursor by d... | 06/05/1990 |
| 4902701 | Tetrazolyl substituted tricyclic compounds and pharmacological compositions thereof Tricyclic compounds of formula (I) ##STR1## wherein X1 is a carboxyl or 5-tetrazolyl group X2 is carbonyl or methylene X3 is hydroxyl or a group --X4 (Cn H2n)X5 where X4 is... | 02/20/1990 |
| 4877887 | Preparation of alkoxy maleic anhydrides The invention relates to novel alkoxy substituted maleimides of the formula ##STR1## where R1 is hydrogen, C1 -C8 -alkyl, C2 -C8 -alkenyl, phenyl or phenylalkyl, and the organic radicals may furthermo... | 10/31/1989 |
| 4864036 | Process for preparing aromatic carboxylic anhydride In accordance with the process of this invention, an improved catalyst for molecular oxidation of a hydrocarbon to form the corresponding carboxylic anhydrides is prepared by the steps of (a) forming a catalyst precursor by depositing on titanium dioxide ... | 09/05/1989 |
| 4855457 | Carboxylic anhydride process In accordance with the process of this invention, an improved catalyst for molecular oxidation of a hydrocarbon to form the corresponding carboxylic anhydrides is prepared by the steps of (a) forming a catalyst precursor by depositing on titanium dioxide ... | 08/08/1989 |
| 4824915 | Functionalized polyphenylene ethers and blends with polyamides Functionalized polyphenylene ether compositions are provided which are particularly useful for effecting compatibility for a blend of polyphenylene ether resin and a polyamide resin. The functionalized-polyphenylene ether is the reaction product of a ... | 04/25/1989 |
| 4670568 | Process of producing n-formylaspartic anhydride A process for producing N-formylaspartic anhydride, which comprises, grinding solid aspartic acid into fine particles; and then reacting said finely ground aspartic acid with formic acid and acetic anhydride.... | 06/02/1987 |
| 4642358 | Acyl modified polyphenylene ether composition Acyl modified polyphenylene ether compositions are provided by combining or reacting a polyphenylene ether polymer and a compound which contains both (i) at least one acyl functional group and (ii) at least one group capable of reacting or associating wit... | 02/10/1987 |
| 4596867 | Disubstituted maleic anhydride compounds Di-substituted maleic anhydride compounds are disclosed of the structural formula ##STR1## wherein R and R1 are selected from the group consisting of aliphatic and phenyl moieties, and R2 is a divalent aromatic moiety. Poly... | 06/24/1986 |
| 4582912 | Process for preparing carboxylic anhydride using improved catalysts In accordance with the process of this invention, an improved catalyst for molecular oxidation of a hydrocarbon to form the corresponding carboxylic anhydrides is prepared by the steps of (a) forming a catalyst precursor by depositing on titanium dioxide ... | 04/15/1986 |
| 4560761 | Quaternary ammonium compounds containing an anhydride group Quaternary ammonium compounds containing an anhydride groups are prepared by halogenating dimethylmaleic anhydride and reacting the halogenated product with a tertiary amine. The products are useful as surfactants, biocides and as cosurfactants in enhance... | 12/24/1985 |
| 4555362 | Method and intermediates for producing -L-aspartyl-L-phenylalanine This invention encompasses a method and intermediates for preparing a commercial sweetening agent, -L-aspartyl-L-phenylalanine methyl ester. The process involves reacting L-aspartic acid with diketene to form N-acetoacetyl-L-aspartic acid which is ... | 11/26/1985 |
| 4550180 | Method for manufacture of N-formylaspartic anhydride In a method for the manufacture of N-formylaspartic acid anhydride which comprises reacting a mixture of aspartic acid, formic acid and acetic anhydride in the presence of an entraining organic solvent, the improvement comprising adding to the mixture, pr... | 10/29/1985 |
| 4526986 | Halomethyl, methyl maleic anhydride and synthesis of bromomethyl, methyl maleic anhydride Quaternary ammonium compounds containing anhydride groups are prepared by halogenating dimethylmaleic anhydride and reacting the halogenated product with a tertiary amine. The products are useful as surfactants, biocides and as cosurfactants in enhanced o... | 07/02/1985 |
| 4526985 | Process for the preparation of the anhydride of N-formyl-L-aspartic acid A process for the preparation of the anhydride of N-formyl-L-aspartic acid by reacting L-aspartic acid with nearly stoichiometric amounts of formic acid and acetic anhydride, under controlled conditions of temperature, reaction and addition times. The pro... | 07/02/1985 |
| 4517371 | Process for the synthesis of carboxylic anhydrides using a vanadium, phosphorus oxygen containing catalyst composition A vanadium, phosphorus oxygen containing catalyst composition capable of partially oxidizing hydrocarbons (e.g., n-butane) to form a carboxylic anhydride (e.g., maleic anhydride), a process for preparing this catalyst, and a process for using this catalys... | 05/14/1985 |
| 4508912 | Process for producing N-carbobenzoxy-L-aspartic anhydride A process for producing a high yield of N-carbobenzoxy-L-aspartic anhydride from N-carbobenzoxy-L-aspartic acid in a very short period using commercially acceptable reaction conditions is disclosed. The process is characterized by reacting N-carbobenzoxy-... | 04/02/1985 |
| 4497958 | Process for oxidizing a carboxylic anhydride with heterogeneously prepared vanadium-phosphorus-oxygen containing catalyst composition A heterogeneous process for preparing a vanadium-phosphorus-oxygen containing catalyst for use in the preparation of carboxylic anhydrides is disclosed. This process employs an activation procedure in an air-hydrocarbon atmosphere.... | 02/05/1985 |