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Class 549/229 - The hetero ring is five-membered


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the hetero ring has five ring members.
No. of patents: 206
Last issue date: 10/18/2011


1            
NumberTitleIssue Date
80396472-amino-bicyclo (3.1.0) hexane-2,6-dicarboxylic ester derivative
A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows ...
10/18/2011
8022231Process for preparing monochloroethylene carbonate and subsequent conversion to vinylene carbonate
Processes for preparing monochloroethylene carbonate include reacting ethylene carbonate with chlorine gas in a liquid phase under irradiation of UV light and introducing a separate feed of an inert gas into the liquid phase. Monochloroethylene carbonate may be subs...
09/20/2011
7888517Process for production of glycidol
The present invention relates to a process for producing glycidol from glycerol carbonate as a raw material with a high yield. The process for producing glycidol according to the present invention includes the steps of (1) reducing a content of a salt having a weak ...
02/15/2011
7772408Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells
Compositions of matter comprising 5-phenylalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or veterinary patients, including autoimmune diseases such as multiple sclerosis. The compound...
08/10/2010
7375224Adenine modified silica-based catalyst, a process for the preparation and use there for the production of cyclic carbonates
The present invention provides an adenine modified solid, ordered, mesoporous, bifunctional, organo-inorganic silica-based catalyst, its method of preparation and also a process for the production of cyclic carbonates of the formula hereinbelow
05/20/2008
7371857Synthesis for hydroxyalkylated heterocyclic bases
A hydroxyalkylated heterocyclic base is prepared by reacting a heterocyclic base with an alkylene carbonate in dimethylacetamide as a solvent, wherein the hydroxyalkylated heterocyclic base is isolated from the solvent using isopropanol or tert-butylmethylether....
05/13/2008
7365214Process for the preparation of cyclic carbonates
The present invention provides an improved process for the preparation of cyclic carbonates which comprises reacting an olefins or its epoxide with carbon dioxide or a mixture of oxygen-containing compound and carbon dioxide, in the presence of zeolite-based catalys...
04/29/2008
7220870Hydrolytic kinetic resolution of cyclic substrates
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisome...
05/22/2007
7199252Process for α,β-dihydroxyalkenes and derivatives
Disclosed is a process wherein a first olefin selected from certain α,β-dihydroxyalkenes and 4-(alkenyl)ethylenecarbonates is reacted with a second olefin reactant to produce an olefin metathesis product. When the first olefin reactant is an optically enriched or ...
04/03/2007
7112633Preparation of a compound containing cyclic and linear carbonate groups
The invention relates to a process for the preparation of compound(s) comprising at least one acrylate or methacrylate group, at least one linear carbonate group and at least one 5-membered cyclic carbonate group. The process comprises (A) a selective ring-opening s...
09/26/2006
7101912Carbidopa prodrugs and derivatives, and compositions and uses thereof
Prodrugs of carbidopa, derivatives of carbidopa prodrugs, methods of making prodrugs of carbidopa and derivatives thereof, methods of using prodrugs of carbidopa and derivatives thereof, and compositions of prodrugs of carbidopa and derivatives thereof are disclosed...
09/05/2006
7098201Heteroaromatic derivatives having an inhibitory activity against HIV integrase
A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is —COORA wherein RA is hydrogen or ester residue, —CONRBRC wher...
08/29/2006
70876353-substituted oxindole β3 agonists
The present invention relates to a β3 adrenergic receptor agonist of formula I: or a pharmaceutical salt thereof; which is capable of increasing lipolysis and energy expenditure in cells and, therefore, is usefu...
08/08/2006
7078538Baccatin III derivatives
A process for the preparation of 14 beta-hydroxy-1,4-carbonate-deacetylbaccatin III and intermediates useful for the preparation of novel taxan derivatives with antitumor activity are disclosed. ...
07/18/2006
7078432Process for the preparation of the 14β-hydroxy-baccatin III-1,14-carbonate
A process for the preparation of 14β-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity. ...
07/18/2006
7067219Additive for nonaqueous-electrolyte secondary battery
The present invention provides an additive which is able to make a non-aqueous-electrolyte secondary cell or a non-aqueous electrolyte electric double layer capacitor which is excellent in low-temperature characteristics, while maintaining a necessary cell propertie...
06/27/2006
7057038Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids
One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer...
06/06/2006
7005496Production of trimethylene carbonate from poly (trimethylene carbonate) by wiped film reactive evaporation
A method for producing trimethylene carbonate poly(trimethylene carbonate which comprises (a) introducing liquid poly(trimethylene carbonate) and an optional catalyst into a wiped film evaporator reactor under a vacuum about 15 kPa or less, said reactor having walls...
02/28/2006
6953800Use of selective antagonists of the α1B-adrenergic receptor for improvement of sexual dysfunction
Described is the use in the treatment of either male or female sexual dysfunction of selective antagonists of the α1B-adrenergic receptor and the pharmaceutical compositions containing them as compounds capable of helping the sexual act avoiding at the s...
10/11/2005
6933394Catalyst for synthesizing alkylene carbonate
The present invention provides an alkylene-carbonate synthesis catalyst comprising a compound insoluble to one phase containing alkylene carbonate produced when the alkylene oxide and carbon dioxide are reacted with the catalyst and soluble to the other phase substa...
08/23/2005
6924379Process for preparation of cyclic carbonate
A catalytic system comprising of Zinc-substituted polyoxometalate, Na12[WZn3(H2O)2(ZnW9O34)2].48H2O and a Lewis base has been discovered to be efficient for chemical fixation of ...
08/02/2005
6921454Elastomer toughened radiation curable adhesives
A radiation curable adhesive composition which includes: a) an α,β-olefinically unsaturated ether monomer component consisting of one or more compounds having the formula: R[O—CH═CHR1]n  (I) where R is...
07/26/2005
6909022Process of removing organic halogen-containing compounds
The present invention relates to a process of removing organic halogen-containing compounds from a liquid stream mainly containing one or more of the compounds selected from the group consisting of glycol, water and alcohol, which process involves contacting the str...
06/21/2005
6861537Tricyclic and tetracyclic taxane intermediates
The synthesis of taxol and other tricyclic and tetracyclic taxanes. ...
03/01/2005
6849626Aza-amino acid derivatives (factor Xa inhibitors 15)
The invention relates to semicarbazides of the general formula I where R1, R2, R3, R4 and I have the meaning indicated in claim 1. The compounds of the formul...
02/01/2005
6831075Heterocyclic substituted pyrazolones
The present invention is directed to novel heterocyclic substituted pyrazolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directed to...
12/14/2004
6828445Process for the preparation of baccatin III derivatives
A process for the preparation of 14β-hydroxy-1,4-carbonate-deacetylbaccatin III and intermediates useful for the preparation of novel taxan derivatives with antitumor activity are disclosed. ...
12/07/2004
6825361Cathodic electrocoating compositions containing hydroxyl-carbonate blocked polyisocyanate crosslinking agent
An improved aqueous cathodic electrocoating composition having a binder of an epoxy-amine adduct and a blocked polyisocyanate crosslinking agent; wherein the improvement is the use of a hydoxyl-carbonate blocked polyisocyanate crosslinking agent. Electrodeposited fi...
11/30/2004
6784307In situ process for preparing quaternary ammonium bicarbonates and quaternary ammonium carbonates
Applicant has discovered an in situ method of preparing quaternary ammonium methocarbonate salts and quaternary ammonium alkylcarbonate salts in high yield from tertiary amines, methanol, and at least one of a cyclic carbonate, an aliphatic polyester (such as a poly...
08/31/2004
6743914Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids
One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer...
06/01/2004
6730783Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR9 and R1-R4, R6-R9, R11, R12, Ra
05/04/2004
6727369Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
Process for the preparation of a derivative or analog of baccatin III or 10-desacetyl baccatin III having a C2 substituent other than benzoate and/or a C4 substituent other than acetate in which the C2 benzoate substituent and/or the C4 acetate substituent of a deri...
04/27/2004
6716874Synergistic insecticide mixtures
The invention relates to insecticidal mixtures comprising compounds of the formula (I) in which X′, Y′, Z′, n, G′, A′ and B′ are as defined above and agonists and/or antagonists of nicotinic acetylcholine rec...
04/06/2004
6716832Arylphenyl-substituted cyclic ketoenols
The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I): in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenalkyl,...
04/06/2004
6706724Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
The invention describes novel substituted aryl compounds that are cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfer...
03/16/2004
6703513Production and use of derivatized homoserine lactones
The present invention provides analogues of autoinducer molecules that are derivatized to allow their attachment to other molecules and surfaces. Libraries of the autoinducer analogues are also contemplated. Also provided are methods for using the compoun...
03/09/2004
6699998Non-aqueous electrolyte and lithium secondary battery using the same
A non-aqueous electrolyte comprising a non-aqueous solvent and a lithium salt dissolved therein, and a cyclic carbonate, linear carbonate, and vinylene carbonate having a chlorine content of 100 ppm or less, and a lithium secondary battery using the same....
03/02/2004
6699890Phosphodiesterase 4 inhibitors
PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: ##STR1## wherein R1, R2 , R3 and R4 are as defined ...
03/02/2004
6693092Arylphenyl-substituted cyclic ketoenols
The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalke...
02/17/2004
6649652Prodrugs for antimicrobial amidines
A methods of treating an infection comprises administering a therapeutically effective amount of a compound described by the Formula (I) ##STR1##...
11/18/2003
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