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| Number | Title | Issue Date |
| 8183394 | Protease inhibitor precursor synthesis The present invention provides a compound having the structure (I) and processes for the production thereof and the intermediates used in such process. ... | 05/22/2012 |
| 8148550 | Method for the production of statins The present invention relates to a process for the production of statins, which are known as HMG-CoA reductase inhibitors. A few of the intermediate compounds for use in the process in accordance with the invention are novel compounds and the invention also relates ... | 04/03/2012 |
| 7678926 | Indole derivatives as selective androgen receptor modulators (SARMS) The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor. ... | 03/16/2010 |
| 7456298 | Synthesis of acetonides from aryl silanes The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for conve... | 11/25/2008 |
| 7432381 | 1,3-oxathiolane-2-thione compounds The present invention relates to 1,3-oxathiolane-2-thione compounds of the general formula (I): wherein R1 and R2 are the same or different, each of which denotes a straight-chain or branched alkoxy re... | 10/07/2008 |
| 7425283 | Cyclic carbonate-modified siloxane, method of making, non-aqueous electrolytic solution, secondary battery, and capacitor A siloxane modified with a cyclic carbonate of the formula: is combined with a non-aqueous solvent and an electrolyte salt to form a non-aqueous electrolytic solution, which is used to construct a secondary battery having i... | 09/16/2008 |
| 7385221 | Silylethynylated heteroacenes and electronic devices made therewith Novel silylethynylated heteroacenes and electronic devices made with those compounds are disclosed. ... | 06/10/2008 |
| 7381349 | Process for producing liquid crystal of desired properties by mixing together at least two rigid rodlike helical polymers with narrow molecular weight distributions and different weight-average molecular weights with chiral side chains A process to produce a polymer liquid crystalline composition having temperature dependency of desired circular polarization selective reflection wave length property by only mixing two or more kinds of starting materials having different weight-average molecular we... | 06/03/2008 |
| 7365213 | Organosilicon compound, organosilicon resin having diol, and processes for producing these [Problems] To provide a novel alkoxysilane having a diol protected, an organosilicon resin which has a diol and the composition of which can be easily regulated, and to processes for producing these. [Means for solving problems] The alkoxysilane is an organos... | 04/29/2008 |
| 7329654 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders mediated by one or more estrogen receptors and processes for their prepar... | 02/12/2008 |
| 7317113 | Process for the preparation of the 14β-hydroxy-baccatin III-1,14-carbonate A process for the preparation of 14β-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity. ... | 01/08/2008 |
| 7312203 | 1-aza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof The present invention relates to 1-aza-dibenzoazulene derivatives, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumo... | 12/25/2007 |
| 7304161 | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding dom... | 12/04/2007 |
| 7288665 | Process for selective derivatization of taxanes Processes for the preparation of taxol and other taxanes through selective derivatization of the C(7) and C(10) hydroxyl groups of 10-DAB, particularly a novel process using a new strategy in which the C(10) hydroxyl group is protected or derivatized prior to the C(... | 10/30/2007 |
| 7285579 | Solventless, non-polluting radiation curable coatings Solventless siloxane epoxy-based coating compositions for use on metals, plastics, wood, and glass are disclosed. The compositions are cationically curable in air by U.V. or by electron beam radiation. The siloxane epoxy coating compositions exhibit excellent film p... | 10/23/2007 |
| 7268239 | Process for the preparation of prostaglandins and analogues thereof Disclosed are processes for the synthesis and purification of prostaglandins and analogues thereof, especially analogues of PGF2α. ... | 09/11/2007 |
| 7244798 | (Meth) acrylic compound having an oxetanyl group and liquid crystal film produced by using same The present invention provides a novel compound which is suitable as the starting material of a side-chain type liquid crystalline polymeric substance having a reactive group which is excellent in reactivity upon fixation of the liquid crystal orientation structure.... | 07/17/2007 |
| 7235593 | Command-cure adhesives Reactive adhesive compositions that can be activated with actinic radiation, manipulated for an extended time and then cured thermally are disclosed. The prepolymer mixture for the reactive adhesive contains a catalyst component and a monomer/oligomer component. The... | 06/26/2007 |
| 7230123 | Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups The invention relates to ureido or carbamate derivatives of crown ethers and of silicon of formula: These derivatives can be grafted to silica gel for the purpose of obtaining supports for the chromatographic sep... | 06/12/2007 |
| 7202370 | Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and th... | 04/10/2007 |
| 7193092 | Chiral diphosphorus compounds and their transition metal complexes The present invention relates to chiral diphosphorus compounds and their transition metal complexes, to a process for preparing chiral diphosphorus compounds and their transition metal complexes and also to their use in asymmetric syntheses. ... | 03/20/2007 |
| 7166583 | 1,3-diaza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof The present invention relates to 1,3-diaza-dibenzoazulene derivatives, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of ... | 01/23/2007 |
| 7115651 | Macrocycles and uses thereof The present invention relates to compounds having the structure (and pharmaceutically acceptable derivatives thereof) wherein R0–R4, Z, X, A—B, D—E, G—J, and... | 10/03/2006 |
| 7109281 | Silyl-acetal compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 09/19/2006 |
| 7102018 | Intermediates and improved processes for the preparation of neplanocin A Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6]dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the pre... | 09/05/2006 |
| 7084289 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 08/01/2006 |
| 7084184 | Actinic ray curable composition, actinic ray curable ink, image forming method, and ink jet recording apparatus Disclosed are an actinic ray curable composition, an actinic ray curable ink, an image recording method, and an ink jet recording apparatus, the actinic ray curable composition containing a photo acid generator, and an oxetane compound I represented by the following... | 08/01/2006 |
| 7078538 | Baccatin III derivatives A process for the preparation of 14 beta-hydroxy-1,4-carbonate-deacetylbaccatin III and intermediates useful for the preparation of novel taxan derivatives with antitumor activity are disclosed. ... | 07/18/2006 |
| 7078549 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 07/18/2006 |
| 7074866 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 07/11/2006 |
| 7067600 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 06/27/2006 |
| 7056559 | Ink-jet image forming method A photocurable ink for ink-jet recording, comprising an oxetane compound having a substituent at the 2-position of the molecule. ... | 06/06/2006 |
| 7053224 | Intermediates and improved processes for the preparation of neplanocin A Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the prep... | 05/30/2006 |
| 7034175 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 04/25/2006 |
| 7034165 | Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones or epothil... | 04/25/2006 |
| 7034171 | Modified silane compounds This invention relates to the reversible protection of hydroxy-silane functional groups by acid cleavable protecting groups. The development of reversible protecting groups greatly enhances the current utility of silanes while introducing further novel applications.... | 04/25/2006 |
| 7030253 | Process for preparing 4-alkyl- or 4-aryl-oxycarbonyl paclitaxel analogs and novel intermediates A process is provided for preparing 4-alkyl- or 4-aryl-oxycarbonyl paclitaxel analogs which includes the steps of converting paclitaxel into a C-7 acylprotected paclitaxel employing an electrophilic protecting group, such as benzoyloxycarbonyl, and converting the C-... | 04/18/2006 |
| 7015243 | Cyclohexyl prostaglandin analogs as EP-receptor agonists The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EP4 agonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following... | 03/21/2006 |
| 7012093 | Multiple fluorescent natural dye compound from a marine organism and method of use thereof The present invention provides a novel compound multiple fluorescent natural dye from a marine organism Holothuria Scabra having a chemical structure of of Si—O—R type wherein silica matrix is an integral part of the compound, taking part in the metabolis... | 03/14/2006 |
| 7005527 | Process for the production of beraprost and its salts The present invention relates to a new process for the preparation of beraprost of formula (I) using new intermediates. ... | 02/28/2006 |
