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| Number | Title | Issue Date |
| 8168806 | Boron chelate complexes Boron chelate complexes of the general formula are described, where X is either —C(R1R2)— or —C(R1R2)—C(═O)—, in which ... | 05/01/2012 |
| 8044221 | Fluorine-containing boronic acid ester compound and method for producing the same A fluorine-containing boronic acid ester represented by the general formula: (R1 is a linear or branched divalent aliphatic hydrocarbon group having 2 to 10 carbon atoms, R2 is a hydrogen atom, an alky... | 10/25/2011 |
| 7951964 | Fluorine-containing boronic acid ester compound and method for producing the same A fluorine-containing boronic acid ester compound (R1: a linear or branched divalent aliphatic hydrocarbon group having 2 to 10 carbon atom, m: 1 to 5, and n: 3 to 7) having a low melting point is produced by rea... | 05/31/2011 |
| 7842823 | Fluorogenic probes for reactive oxygen species The present invention provides a novel class of fluorogenic probes for reactive oxygen species. Exemplary probes of the invention utilize a boronate deprotection mechanism to provide high selectivity and optical dynamic range for detecting H2O2 | 11/30/2010 |
| 7767833 | Stabilized borane-tetrahydrofuran complex A stabilized borane-tetrahydrofuran complex is disclosed. Also disclosed are processes for the preparation of the borane-tetrahydrofuran complex and methods of storing and transporting the prepared complex. The borane-tetrahydrofuran complexes exhibit enhanced shelf... | 08/03/2010 |
| 7750168 | Stabilized deuteroborane-tetrahydrofuran complex A stabilized deuteroborane-tetrahydrofuran complex is disclosed. Also disclosed are processes for the preparation of the deuteroborane-tetrahydrofuran complex and methods of storing and transporting the prepared complex. The deuteroborane-tetrahydrofuran complexes e... | 07/06/2010 |
| 7709663 | Boron chelate complexes Boron chelate complexes of the general formula are described, where X is either —C(R1R2)— or —C(R1R2)—C(═O)—, in which R1, R | 05/04/2010 |
| 7612218 | Process for production of heteroaryl-type boron compounds with iridium catalyst The present invention provides an economically and industrially superior simple process that enables the selective production of an aromatic heterocyclic monoboron compound and aromatic heterocyclic diboron compound at a satisfactory yield and in a desired ratio by ... | 11/03/2009 |
| 7390670 | Signalling compounds and methods for detecting hydrogen peroxide Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is a non-polymeric organic group, B is a boron atom, and each... | 06/24/2008 |
| 7319172 | Process for the preparation of methylheptenone Methylheptenone (2-methyl-2-hepten-6-one) is prepared by reacting 2-methyl-3-buten-2-ol with isopropenyl methyl ether in the presence of hydrogen tris(oxalato)phosphate or hydrogen bis(oxalato)borate. ... | 01/15/2008 |
| 7238819 | Process for preparing isobutylene-based polymers This invention relates to a metal organic compound, a catalytic composition comprising said metal organic compound, a process for homo- or co-polymerizing isoolefines in the presence of said metal organic compound and a method of stabilizing a compound of the genera... | 07/03/2007 |
| 7238826 | Boronate esters The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin, rosuvastatin, pitavastatin, and fluvastatin. ... | 07/03/2007 |
| 7208612 | Crystals of LuxP and complexes thereof A crystal comprising LuxP is obtained, and a binding site for autoinducer-2 (AI-2) identified. The X-ray crystallographic data for LuxP and a LuxP-AI-2 complex is determined and used in a drug discovery method. Pharmaceutical compositions comprising ligands identifi... | 04/24/2007 |
| 7208131 | Method for the production of hydrogen-bis(chelato) borates and alkali metal-bis(chelato)borates Methods are described for the production of hydrogen-bis(chelato)borates of the general formula H[BL1L2] and of alkali metal-bis(chelato)borates of the general formula M[BL1L2] where M=Li, Na, K, Rb, Cs ... | 04/24/2007 |
| 7202370 | Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and th... | 04/10/2007 |
| 7153957 | Regioselective synthesis of CCI-779 A method for regioselective synthesis of CCl-779 based on boronate chemistry is provided. Also provided are novel intermediates useful in this method. ... | 12/26/2006 |
| 7148365 | Process for preparing 5-bromo-2,2-difluorobenzo-1,3-dioxoles The invention relates to a process for preparing 5-bromo-2,2-difluorobenzo-1,3-dioxoles and to the use thereof for preparing medicaments and crop protection agents. ... | 12/12/2006 |
| 7119080 | Boronic ester and acid compounds, synthesis and uses Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and... | 10/10/2006 |
| 7045640 | Method of producing 5-formyl-2-furylboronic acid 5-formyl-2-furylboronic acid is produced by a) adding a base to a composition containing a boric acid ester and 2-furaldehyde, thereby obtaining a reaction mixture and protecting the formyl group of said 2-furaldehyde with a protective group, b) working-up of the re... | 05/16/2006 |
| 6982280 | Epothilone derivatives, a method for the production thereof, and their use The present invention relates to epothilon derivatives, processes for their production and their use in the manufacture of medicaments and plant protection agents. ... | 01/03/2006 |
| 6939985 | Aryl borates The invention provides a process for covalently coupling organic compounds which comprises reacting an aromatic ring compound having a halogen or halogen-like substituent at a coupling position with a diboron derivative in the presence of a Group VIII metal catalyst... | 09/06/2005 |
| 6933290 | 2-{N-(2-amino-3-(heteroaryl or aryl)propionyl)-aminoacyl}-amino}-alkylboronic acid derivatives Disclosed are derivatives of 2-{[N-(2-amino-3-(heteroaryl or aryl)propionyl)-aminoacyl]-amino}-alkylboronic acid, processes for the preparation of such compounds, pharmaceutical preparations, and the use of such derivatives in the preparation of pharmaceutical compo... | 08/23/2005 |
| 6919463 | Signalling compounds for use in methods of detecting hydrogen peroxide Compounds useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is an aromatic or heteroaromatic ring group, B is a boron atom, and... | 07/19/2005 |
| 6916942 | Process for the preparation of C-4 carbonate taxanes A process for the preparation of novel C-4 carbonate taxanes useful as antitumor agents ... | 07/12/2005 |
| 6911551 | Spiro compounds based on boron or aluminum and the use of the same in the electronics industry The present invention relates to substituted boron or aluminum spiro compounds and their use in the electronic industry. The compounds of the invention are used as electron transport material, hole blocking material and/or as host material in organic electroluminesc... | 06/28/2005 |
| 6855848 | Process for preparing bisallylboranes and nonaromatic boronic acids A process for preparing bisallylboranes of the formula (I) by reacting a diene with sodium borohydride in the presence of an oxidant: in an inert solvent, with the borane generated in situ reacting selectively with the... | 02/15/2005 |
| 6756370 | Piperidine alcohols The invention relates to compounds of formula (I), wherein R1, R2 and A have the meanings given in claim 1, are potent 5-HT2A antagonists and are suitable for treating psychoses, schizophrenia, depression, neurological disorders, imp... | 06/29/2004 |
| 6747150 | Boronic ester and acid compounds, synthesis and uses Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and ... | 06/08/2004 |
| 6376532 | Bicyclic metabotropic glutamate receptor ligands The present invention provides bicyclic metabotropic glutamate receptor ligands, as well as compositions comprising such ligands, and and methods for their use.... | 04/23/2002 |
| 6288242 | Processes and intermediates for preparing substituted chromanol derivatives The invention relates to processes for preparing a compound of the formula ##STR1## and the enantiomer of said compound, wherein the benzoic acid moiety is attached at position 6 or 7 of the chroman ring, and R1, R2, and R3 | 09/11/2001 |
| 6281154 | Compounds having one group 13 element, bound with one mono- or di-anionic trident ligand, a method of preparation and application thereof as polymerization catalysts Novel compounds having one group 13 element bound with one mono- or di-anionic tridentate ligand, a method of preparation thereof and use thereof as a copolymerization catalyst.... | 08/28/2001 |
| 6268520 | Tricyclic compounds Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.... | 07/31/2001 |
| 6090950 | Chiral hydride complexes Novel chiral boron and aluminum hydride complexes, compositions comprising the chiral hydride complexes, and methods for their synthesis and use are described. The novel chiral hydride complexes are of the formulas: MBH4-n-a (R*)n (R') | 07/18/2000 |
| 6083903 | Boronic ester and acid compounds, synthesis and uses Disclosed herein are boronic ester and acid compounds, their synthesis and uses. More specifically, disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic e... | 07/04/2000 |
| 6048985 | Borane-tetrahydrofuran complex method of storing and reacting borane-tetrahydrofuran complex A method of stabilizing borane-tetrahydrofuran complex comprises the step of maintaining the temperature of the borane-tetrahydrofuran complex at or below 20° C. A method of reacting a borane reagent with a substrate comprises the steps of heating the bo... | 04/11/2000 |
| 6037505 | Enantioselective oxazaborolidine catalysts The anantoselective borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by performing the reduction in the precence of catalytic amounts of the new and valuable oxazaborolidine compounds of formulas (I) and (II). The c... | 03/14/2000 |
| 6031127 | Process for preparing L-p-boronophenylalanine and intermediate for preparing the same There is disclosed a process for preparing L-p-boronophenylalanine which comprises subjecting a compound represented by the formula: ##STR1## wherein Y represents a protective group selected from the group consisting of benzyloxycarbonyl group, allyl... | 02/29/2000 |
| 6011180 | Acid-stable borates for photopolymerization Compounds of the formula I ##STR1## in which R1 is, for example, C1 -C20 alkyl or phenyl-C1 -C6 alkyl which radicals are unsubstitutedor substituted; R2, R3 and R4 | 01/04/2000 |
| 5990320 | Optically active diphosphine ligands Optically active diphosphine ligands of the formula I, ##STR1## where: R1 is hydrogen, C1 -C10 -acyl, C1 -C10 -alkyl, C2 -C10 -alkenyl, each of which may be linear or branch... | 11/23/1999 |
| 5917075 | Hydrolyzable and polymerizable silanes The hydrolyzable and polymerizable silanes have the formula I, ##STR1## wherein X is hydrogen, a halogen, a hydroxy, an alkoxy group, an acyloxy oup, an alkylcarbonyl group, an alkoxycarbonyl group or --NR22 group; wherein R | 06/29/1999 |