Quotables
"The horse is here to stay, the automobile is only a novelty - fad."
President of Michigan Savings Bank ; 1903
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8008508 | Organocatalyst The present invention provides an organocatalyst of formula (I), wherein R1 is —H, —OH, —O—Si(R4)(R5)(R6) or C1-6alkoxy, in which R4, R5 a... | 08/30/2011 |
| 7951961 | Enantioselective synthesis of pyrrolidines substituted with flavones, and intermediates thereof The present invention relates to an enantioselective synthesis of (+)-trans enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferati... | 05/31/2011 |
| 7834197 | Quaternary ammonium salt, electrolyte, and electrochemical device A quaternary ammonium salt of the formula (1), electrolytic solution and electrochemical device using the salt wherein R1 is straight-chain or branched alkyl having 1 to 4 carbon atoms, R2 is methyl or... | 11/16/2010 |
| 7767831 | Process for preparing renin inhibitors The present invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention provides a process for the manufacture... | 08/03/2010 |
| 7358374 | Purified racemic lasofoxifene and purified lasofoxifene D-tartrate and a method for effective purification of racemic lasofoxifene A method for removing impurities from racemic cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol and purified cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol useful as an estrogen agonist/antagon... | 04/15/2008 |
| 7348356 | Phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer's disease Disclosed are compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's dis... | 03/25/2008 |
| 7335781 | Aminothiol compound The present invention discloses an aminothiol compound having a general formula I wherein R1-R5 are substitutable ligands. Such compound can perform as a superior catalyst in an asymmetric addition reaction of organic metal compounds and aldehy... | 02/26/2008 |
| 7309558 | Use of salt-like structured silicas as charge control agents The present invention relates to the use of salt-like structured silicates, in which the cation is NH4+, H3O+, an alkali metal, alkaline earth metal, earth metal or transition metal ion or a low molecular weight organic ca... | 12/18/2007 |
| 7291753 | Transfer hydrogenation processes and catalysts The invention relates to a process for the reduction of compounds comprising a carbon-carbon (C═C), carbon-oxygen (C═O), or carbon-nitrogen (C═N) double bond, to a corresponding hydrogenated alkane, alcohol or amine, comprising contacting a compound comprising... | 11/06/2007 |
| 7268132 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 09/11/2007 |
| 7259138 | Anti-tumor agents A method for treating subjects with abnormal cell proliferation is provided. The method involves administering to subjects in need of such treatment an effective amount of an agent of Formula I, to inhibit cell proliferation such as that associated with tumor growth... | 08/21/2007 |
| 7244852 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof The invention relates to a process for preparing 2-methylpyrrolidine and, more particularly, specific enantiomers of 2-methylpyrrolidine. Novel intermediates also are described. ... | 07/17/2007 |
| 7244859 | Method for producing δ-aminopentadienoate derivatives The invention is a method for producing δ-aminopentadienoate derivatives of formula (1), the method comprising reacting a streptocyanine derivative of formula (2) with an ester derivative of formula (3) in the presence of an organic base. In formulae (1) to (3), R | 07/17/2007 |
| 7229988 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses The present invention provides novel dialkylhydroxybenzoic acid derivatives containing metal chelating groups and the use of the novel compounds as therapeutics for treating and/or preventing various medical dysfunctions and diseases arising from reactive oxygen spe... | 06/12/2007 |
| RE39558 | 5-Substituted-6-cyclic-5,6,7,8-tetrahydronaphthalen 2-ol compounds which are useful for treating osteoporosis Compounds of this formula are useful for treating or preventing, obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease. ... | 04/10/2007 |
| 7132551 | Ligands for monoamine receptors and transporters, and methods of use thereof One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine tra... | 11/07/2006 |
| 7109217 | Phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer's disease Disclosed are compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzh... | 09/19/2006 |
| 7071359 | Neuropathy improvers containing nitrogenous compounds as the active ingredient A compound represented by the Formula below, and an agent for the remedy of neural damage having the said compound as the active ingredient. [Here, G represents G1 shown below | 07/04/2006 |
| 7071212 | N-(4-carbamimidoyl-phenyl)-glycine derivatives The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: wherein R1, E, X1 to X4 and G1 and G2 are as defined in ... | 07/04/2006 |
| 7067489 | Hematopoietic stimulation Methods and products for stimulating hematopoiesis, preventing low levels of hematopoietic cells and producing increased numbers of hematopoietic and mature blood cells are provided. The methods and products can be used both in vivo and in vitro. The methods involve... | 06/27/2006 |
| 7049446 | Process for chemical reaction of amino acids and amides yielding selective conversion products The invention relates to processes for converting amino acids and amides to desirable conversion products including pyrrolidines, pyrrolidinones, and other N-substituted products. L-glutamic acid and L-pyroglutamic acid provide general reaction pathways to numerous ... | 05/23/2006 |
| 6965038 | Acylated aminothiol compound The present invention discloses an acylated derivative of an aminothiol compound having a general formula II wherein R1-R4 and R6 are substitutable ligands. Such compounds can perform as superior catalysts in asymmetric addition reac... | 11/15/2005 |
| 6953861 | Method of re-sensitizing vancomycin resistant bacteria which selectively cleave a cell wall depsipeptide The present invention relates to pyrrolidine compounds of the general structure: where n is an integer 1-6 and R is hydrogen or a C1 to C6 straight chain or branched alkyl group, and wherein when ... | 10/11/2005 |
| 6949514 | Anti-tumor agents A method for treating subjects with abnormal cell proliferation is provided. The method involves administering to subjects in need of such treatment an effective amount of an agent of Formula I, to inhibit cell proliferation such as that associated with tumor growth... | 09/27/2005 |
| 6946475 | Anticancer calcium channel blockers The present invention is directed to compounds useful as cancer cell inhibitors, compositions containing such compounds and methods for inhibiting proliferation of electrically non-excitable cells. ... | 09/20/2005 |
| 6923835 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres The invention relates to novel bis-para-phenylenediamine derivatives containing a pyrrolidyl group substituted with a cationic radical, to dye compositions containing them and to the process of dyeing keratin fibres using these compositions. The present inven... | 08/02/2005 |
| 6906202 | Purified racemic lasofoxifene and purified lasofoxifene D-tartrate and a method for effective purification of racemic lasofoxifene A method for removing impurities from racemic cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol and purified cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol useful as an estrogen agonist/antagon... | 06/14/2005 |
| 6903108 | Fungicidal mixtures based on amide compounds and pyridine derivatives Fungicidal mixtures comprise as active components a) an amide compound of the formula I A—CO—NR1R2 I in which A is an aryl group or an aromatic or... | 06/07/2005 |
| 6884803 | Phenylalkynes Disclosed are substituted phenylalkynes of formula (I), wherein R1, R2, R3, R4, R5 and n are as defined, compositions containing them, and methods of making and us... | 04/26/2005 |
| 6878736 | Histamine H3 receptor ligands Compounds of formula (I) (and pharmaceutically acceptable salts thereof) are histamine H3 receptor ligands. A in the formula represents (CH2)m, m being from 1 to 3; B is (CH2)n, n being from 1 to 3; x is from 0 ... | 04/12/2005 |
| 6864254 | Inhibitor for 20-hete-yielding enzyme An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is useful especially as a remedy for kidney diseases, cerebrovascular dis... | 03/08/2005 |
| 6861536 | Aminothiol compound The present invention discloses an aminothiol compound having a general formula I wherein R1-R5 are substitutable ligands. Such compounds can perform as superior catalysts in asymmetric addition reactions of organic zinc and aldehyde. According... | 03/01/2005 |
| 6831106 | Vitamin D analogues The present invention relates to novel triaromatic compounds having the general formula (I): as well as to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veteri... | 12/14/2004 |
| 6794511 | Sulfonyl aryl or heteroaryl hydroxamic acid compounds A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl aromatic or heteroaromatic ring hydroxamic acid ... | 09/21/2004 |
| 6787560 | Serotonin reuptake inhibitor A serotonin reuptake inhibitor containing a cyclic amine represented by the following formula, a prodrug thereof, or a pharmaceutically acceptable salt of said cyclic amine or prodrug as an active ingredient: wherein R | 09/07/2004 |
| 6784175 | Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments The use of at least one substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compound and/or one of the enantiomers thereof and/or one of the diastereomers thereof and/or one of the physiologically acceptable salts thereof for producing a medi... | 08/31/2004 |
| 6780857 | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases. ... | 08/24/2004 |
| 6774136 | Substituted 1 and 2 naphthol mannich bases The invention relates to substituted 1 and 2 naphthol Mannich bases, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments. ... | 08/10/2004 |
| 6749988 | Amine compounds, resist compositions and patterning process Novel amine compounds having a nitrogen-containing cyclic structure and a hydrating group such as a hydroxy, ether, ester, carbonyl, carbonate group or lactone ring are useful for use in resist compositions for preventing a resist film from thinning and also for enh... | 06/15/2004 |
| 6723717 | Sulfur-containing thyroxane derivatives and their use as hair growth promotors The present disclosure describes novel compounds of formula (A), wherein R1-R12, X and Y have the meanings given in the specification and compositions containing them which are particularly useful for treating hair loss in mammals, including ar... | 04/20/2004 |
