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| Number | Title | Issue Date |
| 7402678 | Multifunctional amine capture agents Multifunctional compounds having acylsulfonamide amine-reactive groups are described that can be used for the capture of amine containing materials. ... | 07/22/2008 |
| 7368431 | Polypeptide, the conjugate thereof with doxorubicine and a pharmaceutical composition based thereon The inventive polypeptide is embodied in the form of a similar fragment of the epidermal growth factor of aminoacid ranging from 21 to 31 and capable of efficiently binding with the receptor of the epidermal growth factor as a vector for the directed supply of antic... | 05/06/2008 |
| 7348357 | Arylamides The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis of diseases in people or animals, especially diseases of bacterial infection. ... | 03/25/2008 |
| 7329685 | 1-Phenyl-2-oxo-3-sulfonylamino-pyrrolidine derivatives and related compounds as factor Xa inhibitors for the treatment of acute vascular diseases The invention relates to compounds of formula (I): wherein substituents are as defined. ... | 02/12/2008 |
| 7328745 | High molecular weight polyamine salts as clay stabilizing agents A clayish subterranean formation, such as may be encountered in rock surrounding a well bore during hydrocarbon recovery operations may be stabilized with relatively high molecular weight polyamine salts of an imide of polymaleic anhydride. The salts may be unneutra... | 02/12/2008 |
| 7291713 | Branched polyalkylene glycols The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group... | 11/06/2007 |
| 7284610 | Polyamine salts as clay stabilizing agents A clayish subterranean formation, such as may be encountered in rock surrounding a well bore during hydrocarbon recovery operations may be stabilized with a polyamine salt of an imide of polymaleic anhydride. The salt may be unneutralized or partially neutralized. T... | 10/23/2007 |
| 7244848 | Biphenylcarboxamides useful as lipid lowering agents Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyp... | 07/17/2007 |
| 7160905 | Hydroxyethylene compounds with Asp2 inhibitory activity The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase. BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevat... | 01/09/2007 |
| 7102015 | Maleimide compounds in liquid form In accordance with the present invention, there are provided novel thermosetting resin compositions which do not require solvent to provide a system having suitable viscosity for convenient handling. Invention compositions have the benefit of undergoing rapid cure. ... | 09/05/2006 |
| 7053170 | Preparation of high molecular weight polysuccinimides Described are methods of production of polysuccinimides having molecular weights up to 200,000 daltons and higher. The polysuccinimides of the invention are essentially unbranched and uncrosslinked. They can be modified by crosslinking, ring-opening, and/or other fu... | 05/30/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 7019093 | Aqueous developable, photosensitive benzocyclobutene-based oligomers and polymers with high moisture resistance The invention is a photoswitchable benzocyclobutene-based polymer that while remaining aqueous developable, avoids the problem of significant moisture uptake. The oligomer or polymer comprises a polymeric backbone, benzocyclobutene reactive groups, and photoswitchab... | 03/28/2006 |
| 7008634 | Cell growth substrates with tethered cell growth effector molecules Described are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substr... | 03/07/2006 |
| 7005087 | Composition and method for preventing fouling in (meth)acrylic acid processes A composition comprising aminoalkyl imidazoline or alkyl-substituted succinimide antifoulants or mixtures thereof, and use of aminoalkyl imidazolines and alkyl-substituted succinimides to prevent fouling in (meth)acrylic acid manufacturing processes and processes in... | 02/28/2006 |
| 6995262 | Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one compound of the formulae ... | 02/07/2006 |
| 6984658 | Oligo/polysuccinimides, process for producing thereof and their use The invention is directed to oligo/polysuccinimides prepared from alkyl or alkenyl succinic anhydride, containing two or more imide groups, a method for producing such oligo-polysuccinimides, and the use thereof as dispersing agents in lubricant products, plasticize... | 01/10/2006 |
| 6967196 | Sulfonamide compounds and uses thereof In accordance with the present invention, there is provided a novel class of sulfonamide compounds. Compounds of the invention contain a core sulfonamide group. Variable moieties connected to the sulfur atom and nitrogen atom of the sulfonamide group include substit... | 11/22/2005 |
| 6960667 | Fluorescent maleimides and uses thereof The present invention is directed to maleimides and preparation of compounds of the formula I wherein R1 and R2 independently from each other stand for | 11/01/2005 |
| 6960457 | Reversible immobilization of arginine-tagged moieties on a silicate surface This invention provides materials and methods for the site specific attachment of virtually any moiety to a layered silicate surface. The methods involve covalently attaching the moiety to an arginine tag; and contacting the arginine tag with the layered silicate (e... | 11/01/2005 |
| 6960636 | Thermosetting resin compositions containing maleimide and/or vinyl compounds In accordance with the present invention, there are provided novel thermosetting resin compositions which do not require solvent to provide a system having suitable viscosity for convenient handling. Invention compositions have the benefit of undergoing rapid cure. ... | 11/01/2005 |
| 6936700 | Bridged aromatic substituted amine ligands with donor atoms The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hyd... | 08/30/2005 |
| 6916856 | Thermosetting resin compositions containing maleimide and/or vinyl compounds In accordance with the present invention, there are provided novel thermosetting resin compositions which do not require solvent to provide a system having suitable viscosity for convenient handling. Invention compositions have the benefit of undergoing rapid cure. ... | 07/12/2005 |
| 6867171 | Low molecular weight branched alkenyl succinic acid derivatives prepared from low molecular weight polyisobutene and unsaturated acidic reagents This invention is directed to a new low molecular weight branched alkenyl succinic acid derivative that may be prepared by reacting a low molecular weight polyisobutene (PIB) having from about 8 to about 32 carbon atoms, and wherein at least about 50% of the olefini... | 03/15/2005 |
| 6844448 | Main-group metal-based asymmetric catalysts and applications thereof The present invention relates to a method and catalysts for the stereoselective addition of a nucleophile to a reactive π-bond of a substrate. The chiral, non-racemic catalysts of the present invention constitute the first examples of catalysts for nucleophilic add... | 01/18/2005 |
| 6719520 | Method and compounds A method for the treatment of conditions associated with a need for inhibition of GSK-3, such as diabetes, dementias such as Alzheimer's disease and manic depression which method comprises the administration of a pharmaceutically effective, non-toxic amount of a com... | 04/13/2004 |
| 6716872 | Substituted pyrrolidine-2,3,4-trione 3-oxime derivatives which are active as NMDA receptor antagonists Novel substituted pyrrolidine-2,3,4-trione compounds of formula I and methods for preparing the compounds. Also disclosed are pharmarceutical compositions comprising the compounds and methods of using the compounds for t... | 04/06/2004 |
| 6680283 | Fungicidal compositions comprising as active compounds pyrrolidones, and their use in the treatment of plants Agrochemical compositions having fungicidal action and comprising as active compounds compounds of the formula I ##STR1## where R1 is hydrogen, C1 -C6 -alkyl, C1 -C6 -alkylcarbonyl, formyl or C | 01/20/2004 |
| 6642267 | Substituted 1,5-dihydropyrrol-2-one derivatives active as NMDA receptor antagonists for treatment of states of pain A substituted 1,5-dihydropyrrol-2-one compound of formula I: ##STR1## and methods for preparing the compounds. Also disclosed are pharmarceutical compositions comprising the compounds and methods of using the compounds for the treatment or prophylaxis of ... | 11/04/2003 |
| 6586369 | Fungicidal agents containing pyrrolidones as their active agents and use thereof for treating plants Agrochemical compositions having fungicidal action and comprising as active compounds compounds of the formula I ##STR1## where R1 is hydrogen, C1 -C6 -alkyl, C1 -C6 -alkylcarbonyl, formyl or C1 | 07/01/2003 |
| 6582928 | Carbohydrate-directed cross-linking reagents The invention provides heterobifunctional cross-linking reagents and methods of using the cross-linking reagents. The cross-linking reagents of the invention combine a nucleophilic hydrazide residue with an electrophilic maleimide residue allowing couplin... | 06/24/2003 |
| 6552199 | Fluorescence dyes and their use as fluorescence markers The subject matter of the invention are new xanthene derivatives of the formula I, ##STR1## wherein R1,R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and X, Y, are as defined herein. The compounds according to the invention provide molecules that are--due... | 04/22/2003 |
| 6548458 | Succinimide-acid compounds and derivatives thereof Succinimide-acid compounds prepared by reaction of hydrocarbyl-substituted succinic acylating agents with alpha-omega amino acids are disclosed, as well as derivatives thereof useful as lubricity additives, lubricant dispersants, friction modifiers, liqui... | 04/15/2003 |
| 6531594 | Process for producing 1H-3-aminopyrrolidine and derivatives thereof A process for producing 1H-3-aminopyrrolidine and derivatives thereof is disclosed. The process is especially useful for producing optically active 1H-3-aminopyrrolidine and derivatives thereof and in this case comprises reacting an optically active amino... | 03/11/2003 |
| 6515142 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives A process for preparing a compound represented by general formulae (5) and (6) in the following reaction scheme or salts thereof, wherein R1 represents a protective group for a nitrogen atom; R2 represents a methanesulfonyl group or ... | 02/04/2003 |
| 6498004 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity This invention provides a photographic element comprising at least one silver halide emulsion layer in which the silver halide is sensitized with a compound of the formula (a): Ɗ-(t)m -XY' (a) XY'-(t)m -Ɗ (b) Ɗ-(t)m -XY'-(... | 12/24/2002 |
| 6448286 | Imino pyrrolidine derivatives useful as nitric oxide synthase inhibitors The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.... | 09/10/2002 |
| 6420415 | Thiol compounds, their production and use Compounds represented by general formula (1) or salts thereof which have a matrix metalloprotease inhibitory activity and are useful as drugs, wherein the rings A and B represent each an optionally substituted homocycle or heterocycle, etc.; R1... | 07/16/2002 |
| 6410585 | Inhibitors of protein tyrosine phosphatase The present invention comprises small molecular weight, non-peptidic inhibitors of formulae I-VII of Protein Tyrosine Phosphatase 1 (PTP1) which are useful for the treatment and/or prevention of Non-Insulin Dependent Diabetes Mellitus (NIDDM).... | 06/25/2002 |
| 6410733 | Amidine inhibitors of serine proteases Inhibitors of serine proteases are provided having formula (I) ##STR1## wherein X, R1, R2, R3, R4 and R5 are as defined herein. In particular, the compounds bind to factor VIIa, tissue factor/factor X... | 06/25/2002 |
