Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8080673 | Synthetic processes for the preparation of aminocyclohexyl ether compounds This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II): or a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabo... | 12/20/2011 |
| 8013172 | Cycloalkylphenyl substituted cyclic ketoenols The disclosure relates to novel cycloalkylphenyl-substituted cyclic ketoenols of the formula (I) in which J, X, Y, m and CKE are as defined above, to processes and interme... | 09/06/2011 |
| 7868188 | 5-heteroaryl thiazoles and their use as PI3K inhibitors The invention provides thiazole derivatives of formula (I), or pharmaceutically acceptable salts thereof in which Ring A, R1, R2 and R3 are as defined in the specification; a processes for their preparation; pharmaceutical compositio... | 01/11/2011 |
| 7423161 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines The invention relates to compounds having the general formula (I), the method of preparation thereof and the use thereof in organic radical synthesis. The invention also relates to compounds having the formula (II), the method of preparation thereof and a method for... | 09/09/2008 |
| 7402606 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle ... | 07/22/2008 |
| 7314932 | Methods for minimizing thioamide impurities Methods for minimizing the formation of thioamide compounds using decoy agents during reactions, such as thionations of carbonyl compounds containing nitrite groups, are provided. ... | 01/01/2008 |
| 7307044 | 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide The present invention relates to novel 3-biphenyl-substituted, 3-substituted 4-keto-lactams and -lactones of the formula (I) in which A, B, Q, G, W, X, Y and Z are as defined in the disclosure, to processes for their prepar... | 12/11/2007 |
| 7205291 | Carbapenem compounds A compound or its pharmaceutically acceptable salt represented by the following formula: The invention is a carbapenem compound which has a potent antibacterial activity over a broad range of Gram negative and Gr... | 04/17/2007 |
| 7179779 | Cationic bleach activator with enhanced hydrolytic stability A novel cationic bleach activator having an enhanced hydrolytic stability is provided. The novel cationic bleach activator also leads to a reduction in strength loss of cotton fibers compared to conventional hot peroxide bleaching, and achieves this reduction in str... | 02/20/2007 |
| 7135585 | Fungicidal carboxamides Compounds of Formula I are disclosed which are useful as fungicides wherein Q is | 11/14/2006 |
| 7115754 | Pyrrolidine derivatives as oxytocin antagonists The present invention relates to novel pyrrolidine derivative of formula (I), its geometrical isomers, its optically active forms as enantiomers, diastereomers, mixtures of these and its racemate forms, as well as salts thereof, wherein R1 is selected fro... | 10/03/2006 |
| 7005439 | Compounds The invention provides compounds of general formula (I) wherein m, n, Z1, Z2, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined in the specification, process... | 02/28/2006 |
| 6979685 | Cycloalkyl amine compounds and uses thereof Aminocycloalkyl compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of a... | 12/27/2005 |
| 6962943 | Gabusectin derivatives, processes for preparing them and their use The present invention relates to compounds of the formula (I) which are formed by the microorganism ST 003236 (DSM 14476) during fermentation, to a process for preparing and derivatizing them, to a pharmaceutical which... | 11/08/2005 |
| 6953789 | Thiol compounds, their production and use The present invention provides a compound represented by Formula: wherein ring A and ring B may be same or different and each is an optionally substituted homocyclic or heterocyclic ring and the like, each R1 | 10/11/2005 |
| 6943188 | Hydroxyalkyl compounds The invention provides compounds of general formula (I) wherein Q, R, R2, R3, R4, R5, R6, R7, and R8 are as defined in the specification, processes for their preparation, pharmaceutical com... | 09/13/2005 |
| 6933390 | Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate The invention concerns a process for the preparation of N-aryl-aza-heterocycles of the general formula I by reaction of aza-heterocycles with activated aryl halides with use of caesium carbonate without addition of fur... | 08/23/2005 |
| 6919367 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 07/19/2005 |
| 6894005 | Herbicides Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomer of those compounds, are suitable for use as herbicides. ... | 05/17/2005 |
| 6787564 | Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use The present invention relates to some new optically active clausenamide derivatives, process of the preparation thereof, a pharmaceutical composition containing the same and their medical use, particularly their use in the respects of hypoxia protective, nootropic a... | 09/07/2004 |
| 6727275 | Pyrrolidinone derivatives The present invention provides pharmaceutical compositions and novel compounds useful in the treatment of conditions mediated by CCR2, MCP-1 or the interaction thereof. The compounds of the present invention are pyrrolidinones and pyrrolidine-thiones. ... | 04/27/2004 |
| 6689890 | Efficient lactam synthesis Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a γ-lactam, in which an -diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C--H insertion, for example in the... | 02/10/2004 |
| 6642180 | Biphenyl-substituted cyclic ketoenols as pesticides The present invention relates to novel biphenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which W represents hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, X repre... | 11/04/2003 |
| 6642267 | Substituted 1,5-dihydropyrrol-2-one derivatives active as NMDA receptor antagonists for treatment of states of pain A substituted 1,5-dihydropyrrol-2-one compound of formula I: ##STR1## and methods for preparing the compounds. Also disclosed are pharmarceutical compositions comprising the compounds and methods of using the compounds for the treatment or prophylaxis of ... | 11/04/2003 |
| 6583297 | Process and intermediate compounds for the preparation of pyrrolidines Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate... | 06/24/2003 |
| 6576632 | Biaryl compounds useful as anticancer agents The present invention relates to compounds of formula I ##STR1## and to pharmaceutically acceptable salts, hydrates and prodrugs thereof, wherein R1, R2, R3, R4, R5, R10, R11, b,... | 06/10/2003 |
| 6518437 | Process and intermediate compounds for the preparation of pyrrolidines Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate... | 02/11/2003 |
| 6498004 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity This invention provides a photographic element comprising at least one silver halide emulsion layer in which the silver halide is sensitized with a compound of the formula (a): Ɗ-(t)m -XY' (a) XY'-(t)m -Ɗ (b) Ɗ-(t)m -XY'-(... | 12/24/2002 |
| 6486169 | Botanical drug for treatment and prevention of alzhimer's disease The present invention related to safe botanical drug for treatment and prevention of Alzheimer's disease. Specifically, this invention proves a safe botanical drug, Huperzine (HUE) and Clausenamide (CLE) and their preparation. HUE has the following pharma... | 11/26/2002 |
| 6482947 | Substituted (hetero) aryl compounds, process for their preparation, agents containing them and their use as safeners Compounds of the formula I and their salts, as defined in claim 1, are suitable as safeners for protecting crop plants against the phytotoxic side-effects of herbicides.... | 11/19/2002 |
| 6476062 | Chemokine receptor antagonists Novel tetramic acid-type compounds isolated from a CCR-5 active complex produced by fermentation under controlled conditions of a biologically pure culture of the microorganism, Chaetomium globosum Kunze SCH 1705, ATCC 74489., pharmaceutical compositions ... | 11/05/2002 |
| 6472419 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents The present invention relates to new 1-H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) ##STR1## in which A, B, G, X, Y and Z have the meanings given in the description, to processes for their preparation, and to intermediates therefor. The ... | 10/29/2002 |
| 6458965 | Aryl phenyl substituted cyclic ketoenols The present invention relates to novel arylphenyl-substituted cyclic ketonols of the formula (I) ##STR1## in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenylox... | 10/01/2002 |
| 6451843 | Arylphenyl-substituted cyclic keto enols The present invention relates to novel arylphenyl-substituted cyclic ketoenols, their preparation and the use of such ketoenols as pesticides and/or herbicides. The novel arylphenyl-substituted cyclic ketoenols are of the formula (I) ##STR1## in whic... | 09/17/2002 |
| 6437009 | Low foam n-alkyltartarimide and n-alkylmalimide wetting agents This invention provides water-based compositions, particularly coating, ink, fountain solution, adhesive, agricultural and electronics cleaning compositions, manifesting reduced equilibrium surface tension by the incorporation of a surface tension reducin... | 08/20/2002 |
| 6420415 | Thiol compounds, their production and use Compounds represented by general formula (1) or salts thereof which have a matrix metalloprotease inhibitory activity and are useful as drugs, wherein the rings A and B represent each an optionally substituted homocycle or heterocycle, etc.; R1... | 07/16/2002 |
| 6417370 | Arylphenyl-substituted cyclic keto-enols The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogeno-alkoxy, halogenoalkenyl... | 07/09/2002 |
| 6384052 | Anticoccidial compounds Trisubstituted pyrroles are useful in the control of coccidiosis in poultry.... | 05/07/2002 |
| 6380241 | Treatment of diseases using endothelin antagonists A compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.... | 04/30/2002 |
| 6350761 | Benzenamine derivatives as anti-coagulants This invention is directed to benzenamine derivatives of formula (I): ##STR1## wherein A, W, m, n, R1, R2, R3, R4, R5 and R6 are defined herein. These compounds are useful as anti-coagulants.... | 02/26/2002 |