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Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Number | Title | Issue Date |
| 8058454 | Method for preparing 1,3-disubstituted pyrrolidine compounds A process for preparing substituted pyrrolidine compounds, including (5)-2-{1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetamide hydrobromide, commonly known in the art as darifenacin, comprising reacting a pyrrolidine compound with a benzof... | 11/15/2011 |
| 7834194 | Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 The present invention provides compounds of formula I that are useful as potent and selective inhibitors of 11-beta hydroxysteroid dehydrogenase 1. The present invention further provides a pharmaceutical composition which comprises a compound of Formula I, or a phar... | 11/16/2010 |
| 7812178 | Isoquinoline compound and pharmaceutical use thereof The present invention relates to an isoquinoline compound represented by the following formula (I), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for... | 10/12/2010 |
| 7482473 | Coumarin derivative A compound represented by the following general formula (I) or a salt thereof [R1 represents hydrogen atom, or a C1-12 alkyl group; R2 represents a C1-12 alkyl group having one or more maleimide groups, an aryl group havin... | 01/27/2009 |
| 7468443 | Alkyl ether derivatives or salts thereof An alkyl ether derivative represented by the general formula: wherein each of R1 and R2 represents one or more groups selected from a hydrogen atom, a halogen atom, an alkyl group, an aryl group, an ar... | 12/23/2008 |
| 7442806 | Processes for preparing darifenacin hydrobromide The invention encompasses processes for the preparation of darifenacin hydrobromide. ... | 10/28/2008 |
| 7417062 | Substituted arylamides Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer. ... | 08/26/2008 |
| 7402606 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle ... | 07/22/2008 |
| 7361663 | N-acylpyrrolidin-2-ylalkylbenzamidine derivatives as inhibitors of factor Xa This invention is directed to N-acylpyrrolidin-2-ylalkylbenzamidine derivatives which useful for inhibiting the activity of Factor Xa, by contacting said derivatives with a composition containing Factor Xa. The present invention is also directed to compositions cont... | 04/22/2008 |
| 7361755 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines This invention pertains to a novel process for preparing sterically hindered N-substituted alkyloxyamines from alkenes by the transition-metal-catalyzed reaction of a intermediate alkylborane with a sterically hindered nitroxyl radical. ... | 04/22/2008 |
| 7335679 | Wortmannin analogs and methods of using same Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well as tumor formation in a subject are described herein. ... | 02/26/2008 |
| 7314875 | Tricyclic aromatic and bis-phenyl sulfinyl derivatives The present invention provides compounds of the structure: wherein the constituent members are defined herein, including pharmaceutical compositions thereof and methods of treating diseases therewith. ... | 01/01/2008 |
| 7304168 | Photo-caged fluorescent molecules A class of photo-caged and cell permeable fluorescent molecules having high uncaging cross sections, robust fluorescence enhancement, and flexible chemistry for bioconjugation. Some of the photo-caged fluorescent molecules are derived from 6-chloro-7-hydroxy-coumari... | 12/04/2007 |
| 7304081 | Amido compounds and their use as pharmaceuticals The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases... | 12/04/2007 |
| 7288564 | Indole derivatives Compounds of formula (I) or salts or solvates thereof or physiologically functional derivatives thereof are potent binders at the EP4 receptor and are of use in the treatment or prevention of conditions such as a... | 10/30/2007 |
| 7271193 | Inhibitors of cyclin-dependent kinases and their use The present invention relates to novel compounds for the inhibition of cyclin-dependent kinases, and more particularly, to chromenone derivatives of formula (Ia), wherein R1, R2, R3 | 09/18/2007 |
| 7256185 | Control of selective estrogen receptor modulators The treatment of an estrogen sensitive condition by the administration of a selective estrogen receptor modulator is improved by additionally administering a progestationally active compound to the recipient. The additional agent can express both progestational and ... | 08/14/2007 |
| 7250521 | Method for production of Δ-pyrrolines 2,5-Bisaryl-Δ1-pyrrolines of the formula (I) in which Ar1 and Ar2 are as defined in the description can be prepared by reacting aroylpyrrolidinones ... | 07/31/2007 |
| 7247646 | Benzopyranone compounds, compositions thereof, and methods of treatment therewith Benzopyranone Compounds having the following structure: wherein R1, R2, X, Y and n are as defined herein, are disclosed. The Benzopyranone Compounds are useful for t... | 07/24/2007 |
| 7244852 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof The invention relates to a process for preparing 2-methylpyrrolidine and, more particularly, specific enantiomers of 2-methylpyrrolidine. Novel intermediates also are described. ... | 07/17/2007 |
| 7241908 | Process for the direct synthesis of hydrogen peroxide The invention is directed to the preparation of organic or aqueous-organic hydrogen peroxide solutions by direct synthesis from a non-explosive gaseous mixture containing hydrogen and oxygen. The process is carried out in the presence of a noble metal catalyst, usin... | 07/10/2007 |
| 7211394 | Detection of markers in nascent proteins The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 05/01/2007 |
| 7208491 | N-monoacylated o-phenylenediamines Mono-acylated o-phenylendiamines derivatives of formula I wherein X and R are as described herein, have been found useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as c... | 04/24/2007 |
| 7189758 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof A compound of Formula (I) wherein R1, R2, R3, R4, R5, and R6 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutic... | 03/13/2007 |
| 7186722 | 2-heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides Novel Δ1-pyrrolines of the Formula (I) in which R1, R2, R3 and Het have the meanings given in the description, a plurality of processes for prep... | 03/06/2007 |
| 7160877 | Aliphatic nitrogen-containing 5-membered ring compound The present invention is to provide an aliphatic nitrogen-containing 5-membered ring compound represented by the formula [I]: wherein A represents —CH2— or —S—, ... | 01/09/2007 |
| 7157454 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same The invention relates to compounds of formula: These compounds show affinity for the bradykinin receptors with selectivity towards the B1 receptors; they may be used for the preparation of medicinal pr... | 01/02/2007 |
| 7157489 | HIV protease inhibitors Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant strains of HIV, also are disclosed. ... | 01/02/2007 |
| 7119214 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): | 10/10/2006 |
| 7115603 | A-pyrrolines This invention relates to novel Δ1-pyrrolines of formula(I) in which R1, R2, Y and R3 are as defined in the disclosure, to a number ... | 10/03/2006 |
| 7112684 | Compounds and methods for fluorescent labeling Dye reagents useful in labeling biological materials are provided along with methods for their use. ... | 09/26/2006 |
| 7102027 | Adamantanetricarboxylic acid derivatives An adamantanetricarboxylic acid derivative is represented by following Formula (1): wherein X is a hydrogen atom or a hydrocarbon group; and R1, R2 and R3 may be the same as or di... | 09/05/2006 |
| 7098202 | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to sele... | 08/29/2006 |
| 7074829 | Antiestrogens, process for their production and their pharmaceutical use This invention relates to new antiestrogens of the general formula in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure antiestrogens o... | 07/11/2006 |
| 7034051 | Fused bicyclic carboxamide derivatives and methods of their use Fused bicyclic carboxamide derivatives are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed. ... | 04/25/2006 |
| 6989384 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical ... | 01/24/2006 |
| 6989446 | Process for the preparation of 3-aryl-benzofuranones Process for the preparation of compounds of formula I wherein the general symbols are as defined in claim 1, which process comprises reacting a compound of formula V wherein ... | 01/24/2006 |
| 6967216 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor Compounds of formula (I): wherein: X is a group of formula (A) or (B): and R1, R2, R3, R4, ... | 11/22/2005 |
| 6962942 | Azacycloalkanone serine protease inhibitors The present invention is directed to non-peptidic factor Xa inhibitors which are useful for the treatment of arterial and venous thrombotic occlusive disorders, inflammation, cancer, and neurodegenerative diseases. The factor Xa inhibitors provide compounds having F... | 11/08/2005 |
| 6951950 | Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. ... | 10/04/2005 |
