Bizarre Patents
A kissing shield comprised of a thin, flexible membrane and a frame or holder.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7582772 | Process for the synthesis C-2, C-3 substituted N-alkylated indoles useful as CPLAinhibitors The present invention provides method for making a compound of formula 1: comprising the steps of reacting compounds of formulas 2 and 3: to produce a compound of formula 4: ... | 09/01/2009 |
| 7368470 | Substituted 3-pyrrolidine-indole derivatives Substituted 3-pyrrolidine-indole derivatives and methods for their production. Also pharmaceutical compositions containing these compounds and the use of these substances in methods of treatment, in particular treatment of pain and/or depression. ... | 05/06/2008 |
| 7355054 | Indole derivatives The invention relates to 1-(R1)-2-(R2)-3-(Y—X—NH-A- or Z-A-)-4,5,6,7-R)0-4-indoles, and their acid addition salts where the compounds are basic, wherein A is C1-4 alkylene, X is >CH2, >C═O or >C═S, and t... | 04/08/2008 |
| 7307088 | Substituted anthranilic amide derivatives and methods of use Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods fo... | 12/11/2007 |
| 7217706 | Propanolamine derivatives This invention relates to new propanolamine derivatives or salts thereof represented by the following formula [I]: Wherein each symbol is as defined in the specification or salts thereof which have gut selective sympatho... | 05/15/2007 |
| 7186744 | Prostamides for the treatment of glaucoma and related diseases Disclosed herein are compositions comprising an amide related to a prostaglandin and an amine wherein the amine is selected from the group consisting of epinephrine, dopamine, serotonin, and analogs or prodrugs thereof. Also disclosed are certain chemical compounds,... | 03/06/2007 |
| 7173045 | 4-aminomethyl-1-aryl-cyclohexylamine compounds The invention concerns 4-aminomethyl-1-aryl-cyclohexylamine compounds, methods for producing same, pharmaceutical formulations containing said compounds and the use of 4-aminomethyyl-1-aryl-cyclohexylamine compounds for producing medicines and in related methods of ... | 02/06/2007 |
| 7153977 | Ligands and methods for preparing same A process is disclosed for modifying a parent ligand by attaching to the parent ligand a conjugation agent that is reactive with a moiety of a target receptor to which the parent ligand binds such that a covalent bond is formable between the conjugation agent and th... | 12/26/2006 |
| 7115753 | Triaryl cation antibiotics from environmental DNA Disclosed are triaryl cationic compounds that exhibit broad spectrum antibiotic and antifungal activity, pharmaceutical compositions containing the compounds, and methods of treating bacterial and fungal infections using the compounds. The compounds were initially i... | 10/03/2006 |
| 7098233 | 5-halo-tryptamine derivatives used as ligands on the 5-HT and/or 5-HTserotonin receptors Compounds of Formula (I): (I); wherein: R1 and R2 either the same or different, are H or linear or branched C1–C6 alkyl; R3=linear or branched C1–C6 alkyl; R4=halogen, and ph... | 08/29/2006 |
| 7091220 | Substituted indole Mannich bases The present invention relates to substituted indole Mannich bases, processes of preparing substituted indole Mannich base, a medicament containing the same, and a pharmaceutical composition containing the same. ... | 08/15/2006 |
| 7084167 | Calcium receptor active molecules and method for preparing same The invention concerns compounds of general formula (I) wherein: the group X represents a —NR4, —CH═N or —CHR5-NR4-group; the group Y represents an oxygen or sulphur atom or a NR, —CR5, —CHR5-, —CR5=CR6- or —CHR5-CHR6 group provided that when group X... | 08/01/2006 |
| 7049336 | Method for diagnosing neuronal diseases and for treating primary hemostasis deficiency Pharmaceutical compositions for treatment of primary hemostasis deficiency and methods of treatment of primary hemostasis deficiency are disclosed. Also, methods for diagnosing neuronal diseases and for suppressing the immune system are disclosed. Isoforms responsib... | 05/23/2006 |
| 6875884 | Urea derivatives as inhibitors for CCR-3 receptor Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synt... | 04/05/2005 |
| 6797708 | Inhibitors of cytosolic phospholipase A2 This invention provides substituted indole compounds of the general formula: and pharmaceutically acceptable salt forms thereof, and methods for using the compounds as inhibitors of the activity of various phospholipase ... | 09/28/2004 |
| 6794406 | Indole derivatives The invention relates to new indole derivatives, processes for their preparation, and their use in medicaments. ... | 09/21/2004 |
| 6730684 | Fab I inhibitors Compounds of formula (I) and (II) are disclosed wherein, R1, R2, R3, R4, X, A, B, D and Q are as disclosed in the specification, and the compounds are FabI inhibitors useful in... | 05/04/2004 |
| 6541505 | Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is a... | 04/01/2003 |
| 6528650 | Cationic 4-hydroxyindoles, their use for the oxidation dyeing of keratinous fibers, dyeing compositions, and methods of dyeing The invention relates to novel 4-hydroxyindole derivatives comprising at least one cationic group Z, Z being selected from quaternized aliphatic chains, aliphatic chains containing at least one quaternized saturated ring, and aliphatic chains containing a... | 03/04/2003 |
| 6492362 | Compounds and compositions as cathepsin S inhibitors The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.... | 12/10/2002 |
| 6451824 | Sulfonylaminocarboxylic acids Compounds of formula (I) ##STR1## are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading metalloproteinases is involved.... | 09/17/2002 |
| 6420427 | Aminobutyric acid derivatives An aminobutyric acid derivative of the formula (I): ##STR1## (wherein all symbols are as defined in the specification) and salt thereof. salt thereof. The compounds of the formula (I) possess an inhibitory activity on matrix metalloproteinase and are usef... | 07/16/2002 |
| 6414008 | Disubstituted bicyclic heterocycles, the preparation thereof, and their use as pharmaceutical compositions New disubstituted bicyclic heterocycles of general formula Ra --A--Het--B--Ar--E (I) Compounds of general formula I, wherein E is an Rb NH--C(.dbd.NH)-- group, have valuable pharmacological properties, particularly a thrombin-inhibiting ... | 07/02/2002 |
| 6380242 | N-alkylamino-indoles for the treatment of migraine The present invention is directed to compounds useful in the treatment of migraine which have the general formula (II). ##STR1##... | 04/30/2002 |
| 6358994 | 2-acylaminopropanamines as tachykinin receptor antagonists This invention provides compounds of the Formula I: ##STR1## which are useful as tachykinin receptor antagonists. This invention also provides methods employing these compounds, as well as pharmaceutical formulations comprising these compounds.... | 03/19/2002 |
| 6353109 | Certain fused pyrrolecarboxamides; a new class of GABA brain receptor Disclosed are compounds of the formula ##STR1## or the pharmaceutically acceptable non-toxic salts thereof wherein: W represents substituted or unsubstituted aryl or heteroaryl; T is hydrogen, halogen, hydroxyl, amino or alkyl; X is hydrogen, hydroxy, or lower alky... | 03/05/2002 |
| 6281357 | Process for the production of indole derivatives The invention provides a process for the production of a compound of formula I, which comprises reacting a compound of formula II with a compound of formula III, in the presence of a strong base and a palladium(0) catalyst, at an elevated temperature, in ... | 08/28/2001 |
| 6271252 | Cyclic amino acid derivatives as cell adhesion inhibitors Cyclic amino acid derivatives of Formula I are antagonists of VLA-4 and/or 댔ଲ.sub.7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated ... | 08/07/2001 |
| 6162803 | Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression Compounds effective in treating disorders of the serotonin-affected neurological symptoms are provided, such compounds having the following formula: ##STR1## wherein: R1 and R5 are each, independently, hydrogen, halogen, lo... | 12/19/2000 |
| 6159989 | Antagonists of gonadotropin releasing hormone There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both m... | 12/12/2000 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 6107512 | Process for making optically active -amino ketones and selected novel optically active -amino ketones The invention includes selected novel optically active -amino ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitor... | 08/22/2000 |
| 6107499 | Dopamine analog amide The invention involves the formation of a prodrug from a fatty acid carrier and a neuroactive drug. The prodrug is stable in the environment of both the stomach and the bloodstream and may be delivered by ingestion. The prodrug passes readily through the ... | 08/22/2000 |
| 6093409 | Melatonin derivatives and anti-free-radical dermocosmetics comprised thereof Topically applicable dermocosmetic compositions for combating the clinical signs of skin aging and/or for improving the appearance of the skin, the scalp or the hair, comprise an anti-free-radical effective amount of at least one novel melatonin derivativ... | 07/25/2000 |
| 6090839 | Antidiabetic agents The instant invention is concerned with aryl and heteroaryl oxyacetic acid type compounds which are useful antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and related diseases and for lowering tri... | 07/18/2000 |
| 6051588 | Nitroso esters of ଲ-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a pharmaceutical composition including the compounds and methods of treatment of pain and/or inflammation using the compounds and compositi... | 04/18/2000 |
| 6004990 | Meta substituted arylalkylamines and therapeutic and diagnostic uses therefor Novel meta substituted arylakylamine compounds are disclosed. These compounds can be administered as small molecule drugs to treat diseases or conditions associated with insufficient serotonin mediated nerve transmission, such as depression and obesity.... | 12/21/1999 |
| 5998438 | 5-cyclo indole compounds Described herein are compounds selective for a 5-HT1D -like receptor, which have the general formula: ##STR1## wherein A is selected from a six-membered, non-aromatic, optionally substituted carbocycle and a six-membered, non-aromatic, opt... | 12/07/1999 |
| 5942544 | -branched anilines, toluenes, and analogs thereof as factor Xa inhibitors The present application describes m-amidino phenyl analogs of formula I: ##STR1## wherein D can be amidino and E can be phenyl, which are useful as inhibitors of factor Xa.... | 08/24/1999 |
| 5932743 | Methods for the solid phase synthesis of substituted indole compounds The present invention relates to novel substituted indole compounds of formula (I) ##STR1## having pharmacological activity, to processes for their preparation, to solid phase methods for preparing libraries of the compounds, to utilizing librar... | 08/03/1999 |
