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| Number | Title | Issue Date |
| 7423155 | N-sulfonyldicarboximide containing tethering compounds Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 09/09/2008 |
| 7402678 | Multifunctional amine capture agents Multifunctional compounds having acylsulfonamide amine-reactive groups are described that can be used for the capture of amine containing materials. ... | 07/22/2008 |
| 7351838 | N-sulfonyldicarboximide containing tethering compounds Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 04/01/2008 |
| 7208566 | Imide-linked maleimide and polymaleimide compounds The invention is based on the discovery that a remarkable improvement in the performance of maleimide thermosets can be achieved through the incorporation of imide-extended mono-, bis-, or polymaleimide compounds. These imide-extended maleimide compounds are readily... | 04/24/2007 |
| 7015356 | Process for producing dicarboxylic acids A carboxylic acid is produced by oxidative cleavage of a cycloalkane with oxygen and performs a reaction in the presence of a catalyst including an imide compound and a metallic compound, the imide compound having a cyclic imide skeleton represented by the following... | 03/21/2006 |
| 6964976 | Amino alcohol derivatives Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives: wherein R1 and R2 are a hydrogen atom... | 11/15/2005 |
| 6410748 | Alicycli c group-containing monomer A monomer represented by the following general formula (m-1): ##STR1## wherein R is a group having an alicyclic skeleton, R2 s may be the same or different and are individually hydrogen atom, halogen atom or monovalent organic group, X1 | 06/25/2002 |
| 6262302 | N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid pep... | 07/17/2001 |
| 6232258 | Oxygenation catalyst and process for producing a ketone using the same A substrate is contacted with oxygen in the presence of the imide compound shown by the following formula (1) (N-hydroxyphthalimide) and a strong acid, or the imide compound, the strong acid and a co-catalyst (e.g., a transition metal compound) to oxygena... | 05/15/2001 |
| 6160128 | Tritioacetylating reagents and processes for preparation thereof Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of ... | 12/12/2000 |
| 6153652 | N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid pep... | 11/28/2000 |
| 5977182 | O-benzyl oxime ether derivatives and their use as pesticides Compounds of formula (I), wherein Y is hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy, OH, CN, NO2, Si(CH3)3, CF3 or halogen, and T is a group (a) or (b), and wherein the remaining ... | 11/02/1999 |
| 5929217 | Reactive dyes with a benzo-fused heterocycle as anchor Reactive dyes of the formula I ##STR1## where a is 1 or 2, b is 0 or 1, Z1 is hydrogen, C1 -C6 -alkyl, C1 -C6 -alkoxy, halogen, nitro, amino, hydroxysulfonyl, C1 -C6 -alkoxycarbo... | 07/27/1999 |
| 5919790 | Hydroxamate inhibitors of interleukin-1ଲ converting enzyme The present invention relates to compounds that are inhibitors of interleukin-1ଲ converting enzyme that have the Formula II ##STR1## This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock, reperfusio... | 07/06/1999 |
| 5872191 | Process for producing a polyoxyalkylene derivatives substituted with succinimidyl group A process for producing a polyoxyalkylene derivative substituted with succinimidyl group which comprises reacting a polyoxyalkylene compound having carboxyl group at ends with N-hydroxysuccinimide in an inert solvent in the presence of dicyclohexylcarbodi... | 02/16/1999 |
| 5763617 | Cephalosporins A syn isomer in (R) or (S) form or a mixture thereof of a compound of the formula ##STR1## syn isomer, in the (R) or (S) form or in the form of an (R,S) mixture, in the form of an integral salt or their salts with organic or mineral acids wherei... | 06/09/1998 |
| 5760165 | Bisallyloxyimides Monoallyloxyimides, diallyloxyimides and polyallyloxyimides of general Formula I. ##STR1## wherein: X is an integer from 1 to 4 inclusive; R1, R2, and R3 are independently selected from the group comprising hydrogen, ... | 06/02/1998 |
| 5719294 | Process for preparing N-cyclohexylthiophthalimide The preparation of N-cyclohexylthiophthalimide from cyclohexylsulphenyl chloride and phthalimide can be reproduced more reliably if the cyclohexylsulphenyl chloride is prepared in sire by chlorinating dicyclohexyl disulphide.... | 02/17/1998 |
| 5663336 | Substituted diaminophthalimides and analogues A process for the synthesis of compounds of formula I ##STR1## wherein Ar1, Ar2, A1, A2, R and X are as defined in the description, exhibit valuable pharmaceutical properties and are effective especially ag... | 09/02/1997 |
| 5656654 | Arylidene and heteroarylidene oxindole derivatives and process for their preparation Arylidene and heteroarylidene oxindole derivatives of formula (I) ##STR1## wherein, subject to provisos, Y is a bicyclic ring system chosen from naphthalene, tetralin, quinoline and isoquinoline; R is hydrogen or an oxo (.dbd.O) group when Y is tetralin; ... | 08/12/1997 |
| 5650234 | Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces Several poly(ethylene glycol) mixed carbonates and their preparation are closed. These carbonates are synthesized by conversion of polyethylene glycol first to the chloroformate then by reaction with the hydroxyl group of N-hydroxybenzotriazole or 2-hydr... | 07/22/1997 |
| 5646300 | (1H-indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use There are disclosed neuroprotective compounds having the formula ##STR1## wherein the moieties are defined in the specification, and processes for making them.... | 07/08/1997 |
| 5637702 | Sulfur compounds Sulfur compounds of the formula ##STR1## where n is 0 or 2, R1 and R2 are hydrogen, C1 -C6 -alkyl, C1 -C6 -alkoxy, halogen, nitro, amino, hydroxysulfonyl, C1 -C6 ... | 06/10/1997 |
| 5616726 | Optically active aminoalcohol derivatives and method of producing same An object of the present invention is to provide a safe method of commercially producing optically active aminoalcohol derivatives, which serve as intermediates for the synthesis of medicinal chemicals such as the immunopotentiating anticancer agent besta... | 04/01/1997 |
| 5612460 | Active carbonates of polyalkylene oxides for modification of polypeptides Poly(ethylene glycol)-N-succinimide carbonate and its preparation are disclosed. Polyethylene glycol (PEG) is converted into its N-succinimide carbonate derivative. This form of the polymer reacts readily with amino groups of proteins in aqueous buffers. ... | 03/18/1997 |
| 5580987 | Process for preparing 1-aminoacetamidopyrroles There is disclosed a process for the preparation of 1-aminoacetamidopyrroles and 1-amino-2-(substituted)-pyrroles and related compounds of the formula ##STR1## wherein all substituents are defined herein, which are useful as glycine partial agon... | 12/03/1996 |
| 5534533 | Carboxylate derivatives exhibiting phospholipase A2 inhibitory activity Novel carboxylate derivatives exhibiting phospholipase A2 inhibitory activity are disclosed, Specifically, the following compounds of the formula and pharmaceutically acceptable salts thereof are disclosed: ##STR1## wherein A is hydroxy, a... | 07/09/1996 |
| 5508412 | Phthalimides useful as intermediate compounds Unsaturated cyclohexenone oxime ethers I ##STR1## (Q.dbd.H, alkylcarbonyl, benzoyl, alkali metal or alkaline earth metal ion, substituted or unsubstituted ammonium ion, phosphonium ion, sulfonium ion, sulfoxonium ion, an equivalent of a transition me... | 04/16/1996 |
| 5491232 | Sulfur compounds useful for preparation of dyes Sulfur compounds of the formula ##STR1## where n is 0 or 2, R1 and R2 are hydrogen, C1 -C6 -alkyl, C1 -C6 -alkoxy, halogen, nitro, amino, hydroxysulfonyl, C1 -C6 ... | 02/13/1996 |
| 5491144 | Substituted diaminophthalimides and analogues Compounds of formula I ##STR1## wherein Ar1, Ar2, A1, A2, R and X are as defined in the description, exhibit valuable pharmaceutical properties and are effective especially against diseases responsive to th... | 02/13/1996 |
| 5414089 | Long chain carboxylic acid imide ester Provided is a long chain carboxylic acid imide ester (I) represented by the following general formula (I) ##STR1## wherein W is a divalent long chain hydrocarbon group which may optionally be interrupted by one or more groups each independently selec... | 05/09/1995 |
| 5346879 | Plant growth regulator containing a phthalimide derivative Plant growth regulators comprising, as an active ingredient, a substituted dicarboxylic acid derivative having the formula: ##STR1## wherein R1, R2, R3 and R4 are the same as defined in the present specific... | 09/13/1994 |
| 5324844 | Active carbonates of polyalkylene oxides for modification of polypeptides Poly(ethylene glycol)-N-succinimide carbonate and its preparation are disclosed. Polyethylene glycol (PEG) is converted into its N-succinimide carbonate derivative. This form of the polymer reacts readily with amino groups of proteins in aqueous buffers. ... | 06/28/1994 |
| 5304655 | N'-substituted N-amino-3,4,5,6-tetrafluorophthalimides, and processes for their preparation Compounds of the formula ##STR1## in which X is the radical ##STR2## where R1 and R2 are in each case a hydrogen atom, an alkyl-(C1 -C10) group, aryl group, alkyl(C1 -C6)-CO ... | 04/19/1994 |
| 5292759 | O-benzyloxime ethers and crop protection agents containing these compounds O-Benzyloxime ethers of the formula I ##STR1## where 5 X is substituted or unsubstituted CH2, NOalkyl Y is O, S, NR5 R1, R2, R5 are H, alkyl Z1, Z2 are H, halogen, methyl, methoxy, cy... | 03/08/1994 |
| 5288749 | Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors The present invention provides tertiary and secondary amine compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof which are antagonists for alpha-2 adrenoreceptors and which inhibit serotonin (5-hydroxytryptamine, 5... | 02/22/1994 |
| 5281617 | N-succinimidyl and N-phthalimidyl esters of 2-phenylalkanoic acid derivatives as inhibitors of human leukocyte elastase N-succinimidyl and N-phthalimidyl esters of phenylalkanoic acid derivatives which are useful as inhibitors of HLE or HNE.... | 01/25/1994 |
| 5274115 | N'-substituted N-amino-3,4,5,6-tetrafluorophthalimides Compounds of the formula ##STR1## in which X is the radical ##STR2## where R1 and R2 are in each case a hydrogen atom, an alkyl-(C1 -C10) group, aryl group, alkyl(C1 -C6)-CO ... | 12/28/1993 |
| 5252689 | N-hydroxysuccinimide-blocked isopropenyl-alpha, alpha-dimethylbenzyl isocyanate and self-cross linking copolymers thereof A novel, one component self-crosslinking resin and a process for its preparation are provided. The resin is the copolymer of: (I) N-hydroxysuccinimide-blocked meta-isopropenylalpha, alpha-dimethylbenzyl isocyanate; (II) a hydroxy group-containing ethylenically... | 10/12/1993 |
| 5238950 | Inhibitors of platelet-derived growth factor A method of inhibiting the binding of PDGF using compounds of the formula I ##STR1## useful in the treatment of atherosclerosis, cancer, retinal detachment, pulmonary fibrosis, arthritis, psoriasis and glomerulonephritis, and restenosis following ang... | 08/24/1993 |