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| Number | Title | Issue Date |
| 8080671 | Production of low color polyetherimides The production of low color polyetherimides, including its intermediates, such as bisimides and diaryl diether dianhydrides, may be affected by producing an improved purity intermediate of 4-nitro-N-alkylphthalimide. A salt, such as alkali metal carbonate or alkali ... | 12/20/2011 |
| 8022229 | Process for the preparation of alkyl 5-(dicarboximido) levulinate and alkyl 4-oxo-pentenoate A method of manufacturing esters of dicarboxyimidolevulinic acid and alkyl trans-4-oxo-2-pentenoate. This method includes two reaction steps, wherein the first step of said two reaction steps is a bromination of alkyl-levulinate, to obtain alkyl-(3 and 5)-bromolevul... | 09/20/2011 |
| 7329761 | Substituted imides Novel imides are inhibitors of tumor necrosis factor alpha and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is (R)-2-Phthalimido-3-(3′,4′-dimethoxyphenyl)propane | 02/12/2008 |
| 7317110 | Low dielectric constant organo-soluble polyimides The present invention provides a series of easily processable poly(ether-imide)s that are organic-soluble and afford low dielectric constants of films, their organic solutions and their manufacturing process. The poly(ether-imide)s is prepared from a dianhydride and... | 01/08/2008 |
| 7259271 | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation Compounds of formula I: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkyl... | 08/21/2007 |
| 7253291 | Processes for the preparation of N-substituted phthalimides The present invention describes a process for preparing N-substituted phthalimides of Formula I which are widely useful as intermediates in the preparation of organic compounds such as pharmaceuticals ... | 08/07/2007 |
| 7211632 | Perdeuterated polyiimides, their process of preparation and their use as materials which are transparent within the region from 2500 to 3500cm The present invention relates to a deuterated polyimide, the backbone of which comprises an alternation between: at least one repeat unit corresponding to the following formula (I): | 05/01/2007 |
| 7196203 | Phenol derivatives and method of use thereof The present invention provides novel phenol derivatives represented by the formula: wherein the carbon atom marked with (S) represents a carbon atom in S configuration; Z represents the group represented by the f... | 03/27/2007 |
| 7138425 | Phthalimide carboxylic acid derivatives The present invention relates to phthalimide carboxylic acid derivatives of formula (I), methods for their preparation, pharmaceutical compositions containing them and their use in medicine, specifically in the treatment of cancer. (I), wherein X is O or S; R1 ... | 11/21/2006 |
| 7102015 | Maleimide compounds in liquid form In accordance with the present invention, there are provided novel thermosetting resin compositions which do not require solvent to provide a system having suitable viscosity for convenient handling. Invention compositions have the benefit of undergoing rapid cure. ... | 09/05/2006 |
| 7030201 | Bottom antireflective coatings The present invention relates to bottom antireflective coating compositions and polymers useful in making such compositions. ... | 04/18/2006 |
| 6989401 | Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable s... | 01/24/2006 |
| 6960457 | Reversible immobilization of arginine-tagged moieties on a silicate surface This invention provides materials and methods for the site specific attachment of virtually any moiety to a layered silicate surface. The methods involve covalently attaching the moiety to an arginine tag; and contacting the arginine tag with the layered silicate (e... | 11/01/2005 |
| 6939993 | Method for separation of reaction products from catalysts Method for separating reaction product from imide compound catalyst represented by Formula (1) or derivative thereof in reaction mixture obtained by reaction in presence of imide compound catalyst: wherein R1 | 09/06/2005 |
| 6894174 | Water-soluble polyimides and methods of making and using same The present invention provides, among other things, water-soluble polyimides, methods of making water-soluble polyimides, and methods of using water-soluble polyimides, e.g., in optics applications as well as other applications. ... | 05/17/2005 |
| 6875760 | Glucagon antagonists/inverse agonists A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-mediated co... | 04/05/2005 |
| 6855306 | Process for the recovery of sodium nitrite A process is provided for the removal of undesirable organic matter from solutions of sodium nitrite that are generated as byproducts in the manufacture of thermoplastic resins. The process employs certain activated carbon types derived from lignite granular materia... | 02/15/2005 |
| 6821960 | Glucagon antagonists/inverse agonists A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any diseases and disorde... | 11/23/2004 |
| 6756406 | 2-amino-2-alkyl-4 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors The present invention relates to 2-amino-2-alkyl-4 hexenoic and hexynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors. ... | 06/29/2004 |
| 6693202 | Muscarinic receptor antagonists Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscari... | 02/17/2004 |
| 6605626 | Antithrombotic agents This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well a... | 08/12/2003 |
| 6596723 | Fungal efflux pump inhibitors This invention relates to compounds that are efflux pump inhibitors and therefore are useful as potentiators of anti-fungal agents for the treatment of infections caused by fungi that employ an efflux pump resistance mechanism.... | 07/22/2003 |
| 6576769 | Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide ##STR1## which is a useful pharmaceutical agent.... | 06/10/2003 |
| 6570038 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use Hexasubstituted guanidinium chlorides are prepared by a method which affords them in high yield as aqueous solutions, optionally also containing alkali metal chlorides. The solutions may be employed as sources of hexasubstituted guanidinium salts useful a... | 05/27/2003 |
| 6545050 | Aryl sulphonamide amino acid esters and analogues The present invention relates to novel amino acid esters of arylsulphonamides and analogues, to processes for their preparation and to their use for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral ... | 04/08/2003 |
| 6465661 | Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive int... | 10/15/2002 |
| 6436949 | Heterocyclically substituted benzamides and their use Heterocyclically substituted benzamides of the formula I ##STR1## are described, where R1, R2, R3, R4, R5, X, m and n have the meanings given in the description. The novel compounds are useful for con... | 08/20/2002 |
| 6436925 | Substituted benzamides, their production and their use as cysteine protease inhibitors Benzamides of the formula I ##STR1## and its tautomeric forms, possible enantiomeric and diastereomeric forms, E and Z forms, and possible physiologically tolerated salts, in which the variables have the following meanings: R1 --C1 -... | 08/20/2002 |
| 6433184 | Polyamide-imide having head-to-tail backbone The present invention relates to polyamide-imides having head-to-tail backbone and more particularly, to polyamide-imimdes having head-to-tail ragularity to provide excellent heat and chemical resistance, physical and mechanical properties, processability... | 08/13/2002 |
| 6429212 | Medicinal composition It is to provide a cyclic imide derivative which is useful as an active ingredient of a pharmaceutical composition. A pharmaceutical composition which comprises, a cyclic imide derivative represented by the general formula (I): ##STR1## wherein Q | 08/06/2002 |
| 6352958 | Cycloimido-substituted benzofused heterocyclic herbicides Novel herbicidal compounds, compositions containing them, and methods for their use in controlling weeds are disclosed. The novel herbicidal compounds are represented by formula I: ##STR1## where J is a 1-substituted-6-trifluoromethyl-2,4-pyrimidinedione-... | 03/05/2002 |
| 6313122 | Antithrombotic agents This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its... | 11/06/2001 |
| 6294569 | Pyrrolidinyl and pyrrolinyl ethylamine compounds as kappa agonists A compound of the following formula: ##STR1## and the salts thereof, wherein A is hydrogen, halo, hydroxy, or the like; the broken line represents an optional double bond with proviso that if the broken line is a double bond, then A is absent; Ar1 | 09/25/2001 |
| 6268520 | Tricyclic compounds Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.... | 07/31/2001 |
| 6251354 | Process for recovering sodium nitrite The present invention provides a process for recovering a metal nitrite, e.g., sodium nitrite, from a reaction mixture formed from an aromatic displacement reaction such as the synthesis of an aromatic bis(ether phthalimide) in an organic non-polar solven... | 06/26/2001 |
| 6235934 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use Hexasubstituted guanidinium chlorides are prepared by a method which affords them in high yield as aqueous solutions, optionally also containing alkali metal chlorides. The solutions may be employed as sources of hexasubstituted guanidinium salts useful a... | 05/22/2001 |
| 6218389 | Acyclic metalloprotease inhibitors The invention provides compounds of formula ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of... | 04/17/2001 |
| 6214857 | Substituted alkanohydroxamic acids and method of reducing TNF levels Imido and amido substituted alkanohydroxamic acids reduce the levels of TNF and inhibit phosphodiesterase in a mammal. A typical embodiment is 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide.... | 04/10/2001 |
| 6160128 | Tritioacetylating reagents and processes for preparation thereof Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of ... | 12/12/2000 |
| 6160126 | Synthetic Intermediates for the preparation of N, N'-Di-substituted isothiourea derivatives and N-cyclic(methyl)-N'-Substituted isothiourea derivatives Novel Intermediates ##STR1## wherein R is a substituted or unsubstituted hydrocarbon residue or acyl group; X is an electron withdrawing group; Y1 and Y2, which are the same or different, are each independently oxygen or sulfur;... | 12/12/2000 |
