Bizarre Patents
Smoking Cessation Lighter and Method
A lighter for tobacco products suppresses the urge to smoke by operant conditioning.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8148547 | C-substituted diindolylmethane compositions and methods for the treatment of multiple cancers The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to meth... | 04/03/2012 |
| 8093404 | Macrocyclic dyes having aryl moieties Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3′-position, their bioconjugates and their uses are described. 1,3′-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1′-... | 01/10/2012 |
| 8067617 | Indolinone derivatives and process for their manufacture The present invention relates to specific indolinone derivatives, namely the compounds of formula, in which R1 represents an hydrogen atom or a group, and R2 and R3 each represent an hydrogen atom or R2 and R3 t... | 11/29/2011 |
| 8063233 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives Methods for treating cognitive/attention deficit disorders in general using tetrahydroindolone derivatives and analogues, particularly tetrahydroindolone derivatives or analogues in which the tetrahydroindolone derivative or analogue is covalently linked to another ... | 11/22/2011 |
| 7960567 | Compounds and methods useful for treating asthma and allergic inflammation Compounds, compositions and methods that are useful in the treatment of inflammatory and immune-related diseases and conditions are provided herein. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in... | 06/14/2011 |
| 7884218 | Benzoindole-based compound and dye-sensitized solar cell using the same A benzoindole-based compound represented by Formula 1 below, a dye including the benzoindole-based compound, and a dye-sensitized solar cell including the dye: is prepared at a low cost, has a high molar absorption coeffici... | 02/08/2011 |
| 7741495 | Indoline-sulfonamides compounds A series of indoline-sulfonamide compounds is disclosed. The formula of indoline-sulfonamide compounds is shown as formula (I). In formula (I), R1 is H or halogen; R2 is Ar, Ar—C(O)—, Ar—CH2—, Ar—SO2—, Ar—Oâ€... | 06/22/2010 |
| 7632955 | Indole compounds Indole compounds of the formula: wherein L1, L2, R1, R2, Ra, Rb, Rc, Rd, and Re are defined herein. Also disclosed are metho... | 12/15/2009 |
| 7619095 | Process for the preparation of indolone derivative A process for the preparation of 4-[2-(Di-n-propylamino)ethyl]-2,3-dihydro-1H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen a... | 11/17/2009 |
| 7534897 | Indole arylsulfonaimide compounds exhibiting PGD 2 receptor antagonism A compound having CRTH2 receptor antagonism, represented by the following formula (I). The compound is useful for the treatment of allergic diseases having a relation to eosinophils and the like. A compound of the formula (I): ... | 05/19/2009 |
| 7531670 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives Methods for treating cognitive/attention deficit disorders in general using tetrahydroindolone derivatives and analogues, particularly tetrahydroindolone derivatives or analogues in which the tetrahydroindolone derivative or analogue is covalently linked to another ... | 05/12/2009 |
| 7504520 | Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description. ... | 03/17/2009 |
| 7491831 | PPAR active compounds Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile. ... | 02/17/2009 |
| 7476746 | PPAR active compounds Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile. ... | 01/13/2009 |
| 7429612 | Indoline compound and medicinal use thereof The present invention provides an indoline compound represented by the formula (I) wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition contai... | 09/30/2008 |
| 7414054 | 3-(arylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. ... | 08/19/2008 |
| 7414139 | Catalytic antioxidants and methods of use The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some em... | 08/19/2008 |
| 7407983 | Indole derivatives substituted with long-chain alcohols and medicaments containing them Provided is an indole long-chain alcohol, or a hydrate or an isomer thereof, represented by the following formula (I): wherein R1, R2, R3 and R4 each independently represent a hyd... | 08/05/2008 |
| 7405305 | Pyrrole-2, 5dione derivatives and their used as GSK-3 inhibitors The present invention provides kinase inhibitors of Formula (I) ... | 07/29/2008 |
| 7405236 | Indole derivatives comprising an acetylene group This invention is directed to compounds of the formula (I): wherein one of R6, R7, R8 and R9 is and X, R1 to R12,... | 07/29/2008 |
| 7399780 | 3-Heterocyclyl-indole inhibitors of glycogen synthase kinase-3 The present invention provides new compounds of formula Ia and Ib: as well as a process for their preparation and new intermediates used therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in ... | 07/15/2008 |
| 7388100 | Tertiary amine compounds An object of the present invention is to provide an organic semiconductor device comprising a semiconductor layer containing a compound with improved cohesive force, controllable molecular orientation, high packing property, high overall electrical conduction, high ... | 06/17/2008 |
| 7384973 | Materials and methods for treating hypercholesterolemia The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can ... | 06/10/2008 |
| 7381739 | 2,4-substituted indoles and methods of use The present invention provides a compound of the formula: a pharmaceutically acceptable salt or a prodrug thereof, where R1, R2, R3, R4, p and n are those defined herein. The pres... | 06/03/2008 |
| 7375126 | Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor The present invention discloses novel compounds of general formula (I) or a pharmaceutically acceptable salt or prodrug thereof (in which X1-X5, R5-R8b, Z1-Z2 | 05/20/2008 |
| 7375118 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-indole molecules that are cellu... | 05/20/2008 |
| 7371769 | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-Dreceptors and serotonin reuptake sites The present invention relates to a group of novel tetrahydropyridin-4-yl indoles with a dual mode of action: serotonin reuptake inhibition and affinity for dopamine-D2 receptors, to methods for the preparation of these compounds and to novel intermediates... | 05/13/2008 |
| 7365091 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful fo... | 04/29/2008 |
| 7358272 | Methods of using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4 acetylaminoisoindoline 1,3-dione Stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, substantially free of its (−) isomer, and prodrugs, metabolites, polymorphs, salts, solvates, hydrates, and clathrates thereof are discussed. Also d... | 04/15/2008 |
| 7348354 | Cyclohexylurea compounds Cyclohexylurea compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and the use of such compounds as pharmaceutically active agents with nociceptin/ORL1 receptor sys... | 03/25/2008 |
| 7348439 | 2-aryl-3-(aminoaryl)-3-(hydroxyaryl)phthalimidine compounds and methods for making them Compounds and methods for preparing 2-aryl-3-(aminoaryl)-3-(hydroxyaryl)phthalimidines having a formula of: wherein R1 is independently selected from a group consisting of a hydrocarbyl radical, a nitro radical, ... | 03/25/2008 |
| 7345180 | Compound inhibiting dipeptidyl peptidase IV A dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. A compound represented by the following general formula or a pharmaceutically acceptable salt thereof: | 03/18/2008 |
| 7342038 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation The present invention provides substituted 3,3-diphenyl indole compounds, as well as analogues thereof, which are specific potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a ther... | 03/11/2008 |
| 7342039 | Substituted indole oximes The present invention relates to substituted indole oximes and methods of using them. ... | 03/11/2008 |
| 7335678 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1(VR1) receptor Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity, wherein X1, X2, X3, X | 02/26/2008 |
| 7332521 | Substituted indoles The present invention relates generally to substituted indoles such as substituted 1H-indole-2-carboxylic acid derivatives, and methods of using them. ... | 02/19/2008 |
| 7332614 | Process for cross coupling indoles The present invention provides a process for making a compound of general formula I: wherein: R=H or C1-8alkyl X=C3-C8cycloalky... | 02/19/2008 |
| 7323608 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds One aspect of the present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-sulfur bond between the sulfur atom of a t... | 01/29/2008 |
| 7317025 | Non-peptidic NPY Y2 receptor inhibitors The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurologica... | 01/08/2008 |
| 7317027 | Azaindole-derivatives as factor Xa inhibitors The present invention relates to compounds of the formula I wherein R0, R1, R2, R3, Q, V, G and M are as defined herein. The compounds of the formula I are valuable pha... | 01/08/2008 |
