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Patent No. 5500234

Crispy Chip Sandwich and Process of Producing a Sandwich Product

A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.

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Class 548/452 - Bicyclo ring system having the five-membered hetero ring as one of the cyclos (e.g., octahydroindoles, etc.)


Subclass of Class 548 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the polycyclo ring system consists of
No. of patents: 374
Last issue date: 07/05/2011


1                    
NumberTitleIssue Date
7973174Process of making 3-aminopentanenitrile
A process for making 3-aminopentanenitrile from a crude 2-pentenenitrile (“crude 2PN”) comprising 2-pentenenitrile, 2-methyl-2-butenenitrile, and 2-methyl-3-butenenitrile includes contacting the crude 2PN with an ammonia-containing fluid and water. The ammonia-c...
07/05/2011
7973173Process for the synthesis of an ACE inhibitor
A process for the synthesis of trandolapril which comprises condensing N—[I—(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride with trans octahydro-1H-indole-2-carboxylic acid in a first organic solvent comprising a water immiscible inert organic so...
07/05/2011
7935831Process for the preparation of 2-azabicyclo[3.3.0]octane-3-carboxylic Acid Derivatives
The present invention is aimed at a process for the preparation of compounds of the general formula (I). The objective process is in this case based on the Michael reaction of compounds of the general formula (III)
05/03/2011
7932402Process for preparing an intermediate to opioid receptor antagonists
The invention provides an efficient method for preparing 3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide by hydrogenation, under controlled conditions, of an amino-protected 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)benzamide intermediate in which the amino-protecting group...
04/26/2011
7923569β Crystalline form of the arginine salt of perindopril, a process for its preparation and pharmaceutical compositions containing it
β-crystalline form of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.
04/12/2011
7732620Process for crystallization of Ramipril and preparation of a hydrated form thereof
The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino]propanoyl]octahydro cyclopenta[b]pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and i...
06/08/2010
7534896Process for the synthesis of perindopril and its pharmaceutically acceptable salts
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
05/19/2009
7465811Indoline compounds
Sulfonylindoline compounds of formula I, wherein R1 through R4, Y and Z have defined meanings, a process for preparation of such compounds, and the use as pharmaceutically active substances, particularly for the treatment o...
12/16/2008
RE40558Therapeutic uses of di-aryl acid derivatives
The use of diaryl acid derivatives of formula (I) or pharmaceutically acceptable salts, N-oxides, hydrates or solvates thereof, wherein the variables shown are defined in the disclosure, and their pharmaceutical compositions as P...
10/28/2008
7425574Benzofuran oxyethylamines as antidepressants and anxiolytics
Novel benzofuranoxyethylamines of the formula (I), in which R1, R2, R3, R4, m and n have the meanings indicated in Patent Claim (1), which have a strong affinity to the 5 HT1A receptors and/or 5HT1D ...
09/16/2008
7420063Process for preparing a dipeptidyl peptidase IV inhibitor and intermediates employed therein
A process is provided for preparing a dipeptidyl peptidase IV inhibitor of the structure is treated with TFAA in isopropyl acetate to protect the tertiary hydroxyl group as a trifluoroacetate group to form 4
09/02/2008
7417153Method for the production of 3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol derivatives
A method for the production of acetals and ketals of 3-amino-5-(hydroxymethyl) cyclopenlane-1,2-diols of formula (I): (and/or the enantiomer), where R1 is H, C1-6-alkyl, C3-8-cycloalkyl or b...
08/26/2008
7411074Process and intermediates for the preparation of the thienopyrrole derivatives
A process for preparing a compound of formula (I) where R4 and R5 are as defined in the specification; and R6 is hydrogen or a protecting group, which process comprises cyclisation of a compound of formula (II) where R4, R...
08/12/2008
74109933,6-disubstituted azabicyclo [3.1.0] hexane deriviatives useful as muscarinic receptor antagonists
This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0] hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory, urinary an...
08/12/2008
7407983Indole derivatives substituted with long-chain alcohols and medicaments containing them
Provided is an indole long-chain alcohol, or a hydrate or an isomer thereof, represented by the following formula (I): wherein R1, R2, R3 and R4 each independently represent a hyd...
08/05/2008
7388027Bicyclic compounds as modulators of androgen receptor function and method
The present invention relates to bicyclic compounds according to formula I, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for examp...
06/17/2008
7378440Substituted benzoylureido-o-benzoylamides, process for their preparation and their use
The invention relates to substituted benzoylureido-o-benzoylamides and to their physiologically tolerated salts and physiologically functional derivatives. The invention relates to compounds of the formula I in which...
05/27/2008
7371875Cytotoxic agents and methods of use
Disclosed are compounds that inhibit proteasomic activity in cells. Also disclosed are pharmaceutical compositions comprising such compounds as well as methods to treat conditions, particularly cell proliferative conditions, such as cancer and inflammatory condition...
05/13/2008
7368580Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
05/06/2008
7358372Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
04/15/2008
7358373Cathepsin K inhibitors
The present invention provides a compound of the Formula: a pharmaceutically acceptable salt, a solvate, or a prodrug thereof, wherein m, n, Ar1, R1, R2, R3, R4, and R
04/15/2008
7348351Substituted 3-alkyl and 3-arylalkyl -indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
The invention formula substituted 3-alkyl and 3-arylalkyl 1H indol-1yl acetic acid derivatives which are useful as inhibitors of plasminogen activator inhibitor (PAI-1) useful for treating fibrinolytic disorders, the compounds having the structure ...
03/25/2008
7345081Azabicyclo-octane inhibitors of IAP
The invention provides novel inhibitors of IAP that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: X1 and X2 are independently O or S; L is...
03/18/2008
7332614Process for cross coupling indoles
The present invention provides a process for making a compound of general formula I: wherein: R=H or C1-8alkyl X=C3-C8cycloalky...
02/19/2008
7323575Process for the synthesis of (2S)-indoline-2-carboxylic acid
Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts. ...
01/29/2008
7323488Chromogenic enzyme substrates
This invention provides novel chromogenic enzyme substrates which are indoxyl β-D-ribofuranosides. A process for their production is provided. Methods for detecting β-D-ribofuranosidase activity are given. The advantages of these novel compounds includes: detectin...
01/29/2008
7317010Thieno-pyrrole compounds as antagonists of gonadotropin releasing hormone
The invention relates to a group of novel thieno-pyrrole compounds of Formula (I), wherein: R1, R2, R4, R5, R6, R6a, R7, R8, A and ...
01/08/2008
7317025Non-peptidic NPY Y2 receptor inhibitors
The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurologica...
01/08/2008
7312342Process for the preparation of (3-cyano-1h-indol-7-yl) (4-(4-fluorophenethyl) piperazin-1-yl)-methanone and salts thereof
The present invention relates to a process for the preparation of (3-cyano-1H-indol-7-yl)[4-(4-fluorophenethyl)piperazin-1-yl]-methanone and salts thereof, characterised in that an indole ester of the formula II in which R is as defined in Claim 1, is converter into...
12/25/2007
73123416-aryl-imidazo[1,2-a] pyrazin-8-ylamines, method of making, and method of use thereof
A novel composition comprises a compound of Formula 1 the pharmaceutically acceptable salts, hydrates, solvates, crystal forms, diastereomers, prodrugs, or mixtures thereof. The composition is of particular utili...
12/25/2007
7309717Process and intermediates for the preparation of (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylates or salts thereof
In one embodiment, the present application relates to a process of making a compound of formula I. and to certain intermediate compounds that are made within the process of making the compound of formula I. ...
12/18/2007
7288562Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists
This invention generally relates to the derivatives of novel 3,6 disubstituted azabicyclo[3.1.0] hexane's. The compounds of this invention are MUSCARINIC receptor antagonists which are useful, inter-ail for the treatment of various diseases of the respiratory, urina...
10/30/2007
7288661Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1-indole-2-carboxylic acid compounds and application in the synthesis of perindopril
Process for the synthesis of compounds of formula (I): wherein R represents a hydrogen atom or a protecting group for the amino function. Application in the synthesis of perindopril and pharmaceutically a...
10/30/2007
7279494Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
The present invention provides certain [3.1.0] bicyclic oxazolidinone derivatives of formula I or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions c...
10/09/2007
7279583Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof
Process for the industrial synthesis of perindopril of formula (I): and pharmaceutically acceptable salts thereof. ...
10/09/2007
7273885Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents....
09/25/2007
72651473,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0]hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory, urinary and...
09/04/2007
7265148Substituted pyrrole-indoles
The present invention relates generally to substituted pyrrole-indoles such as substituted pyrrole-indoles, and methods of using them. ...
09/04/2007
7259179Kinase inhibitors
A compound of the general formula: or pharmaceutically acceptable salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating protein kinase-associated disease states usin...
08/21/2007
7259250C-nitroso compounds and use thereof
A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th...
08/21/2007
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