Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8067616 | Total synthesis of salinosporamide A and analogs thereof The present invention relates to certain compounds and to methods for the preparation of certain compounds that can be used in the fields of chemistry and medicine. Specifically, described herein are methods for the preparation of various compounds and intermediates... | 11/29/2011 |
| 7384946 | Mmuscarinic acetylcholine receptor antagonists Novel dimeric benzoazabicyclohepatane compounds, pharmaceutical compositions, processes for their preparation and use thereof in treating M3 muscarinic acetylcholine receptor mediated diseases are disclosed. ... | 06/10/2008 |
| 7144913 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists Dihydropyrroloindoles and tetrahydropyridoindoles are prostaglandin receptor antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma. ... | 12/05/2006 |
| 7141578 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. ... | 11/28/2006 |
| 7135494 | Antitumoral carbazoles The invention provides a compound of formula (I). This invention relates to heterocyclic compounds. It further relates to methods for their preparation, compositions cotaining them and their use as a medicament, particularly as a medicament for the treatment and pro... | 11/14/2006 |
| 7081531 | Bridged bicyclic amine derivatives useful as CCR-3 receptor antagonists Compounds having the formula (I), Ar—(F)-(E)-(CR3R4)—(CHR5)m-(T)-(Q)-Ar1, are useful as CCR-3 receptor antagonists, wherein T is a bridged heterocyclyl group having one N atom and a bridg... | 07/25/2006 |
| 7074534 | Polymeric charge transport compositions and electronic devices made with such compositions The present invention relates to polymeric charge transport compositions. The invention further relates to electronic devices in which there is at least one active layer comprising such charge transport compositions. ... | 07/11/2006 |
| 7022729 | Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexanes which are systemically-active as NMDA, 5HT3, and nicotinic receptor antagonists, pharmaceutical compositions comprising the same, method of preparation thereof, and method of tr... | 04/04/2006 |
| 6946455 | Interstrand crosslinking agents for DNA and compounds therefor Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked: A-L-B-X-B-L-A (I) wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical... | 09/20/2005 |
| 6887868 | Therapeutic 5-HT ligand compounds The present invention provides compounds of Formula (I): wherein: R1, R2, R3, R4, R5, R6 R7, R8, n, m, and X have any of the value... | 05/03/2005 |
| 6610685 | Fused indole derivatives The present invention is a chemical compound of formula (I) ##STR1## or a pharmaceutically acceptable salt, solvate and ester thereof, wherein R1 to R4 and n are as defined in the specification. A compound of formula 1 is useful as a... | 08/26/2003 |
| 6608098 | Isoindole derivatives This invention relates to compounds represented by the general formula [I] ##STR1## wherein, R represents an azido group, etc., R1 and R2 are the same or different and represent hydrogen atoms, etc., R3 and R4 are th... | 08/19/2003 |
| 6514984 | Treatment for alzheimer's disease A method is disclosed for the prevention and treatment of Alzheimer's disease by administering to a human in need thereof an effective amount of a substituted tricyclic sPLA2 inhibitor.... | 02/04/2003 |
| 6448284 | Substituted tricyclics A class of tricycles is disclosed together with the use of such for inhibiting Spla2 mediated release of fatty acids for the treatment of conditions such as septic shock.... | 09/10/2002 |
| 6433175 | Pyrroloindoles, pyridoindoles and azepinoindoles as 5-ht2c agonists A chemical compound of formula (I), wherein n is 1, 2 or 3; R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 to R7 are independently selected from hydrogen, halogen, hydro... | 08/13/2002 |
| 6316486 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides The present invention relates to new compounds of the formula (I) ##STR1## in which X represents halogen, Y represents halogen or alkyl and Z represents halogen or alkyl, with the proviso that always one of the radicals Y and Z represents halogen while the oth... | 11/13/2001 |
| 6268510 | Rearrangement process and tricyclic and tetracyclic compounds A rearrangement process for the preparation of a 6,5,5-tricyclic, a 6,6,5-tricyclic and 6,5,5,7-tetracyclic ring system is disclosed.... | 07/31/2001 |
| 6133452 | Synthesis of bisindolylmalimides The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is very efficient and robust macrocyclization methodol... | 10/17/2000 |
| 6083971 | Certain oxopyrolo-pyrrole derivatives having thrombin inhibiting activity Compounds of the formula ##STR1## wherein R1 is lower-alkyl, cycloalkyl or phenyl, R2 is H, OH or C(O)O-A, wherein A is lower-alkyl, cycloalkyl or phenyl, and R3, R4 and R5 are either methyl or R... | 07/04/2000 |
| 6071945 | 8H-thieno-[2,3-b]pyrrolizin-8-one compounds A compound selected from those of formula (I): ##STR1## wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl o... | 06/06/2000 |
| 6051588 | Nitroso esters of ଲ-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a pharmaceutical composition including the compounds and methods of treatment of pain and/or inflammation using the compounds and compositi... | 04/18/2000 |
| 5990319 | Synthesis of bisindolylmaleimides The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is a very efficient and robust macrocyclization method... | 11/23/1999 |
| 5891900 | Oxopyrolo-pyrrole derivatives having thrombin inhibiting activity Compounds of the formula ##STR1## wherein R1 is lower-alkyl, cycloalkyl or phenyl, R2 is H, OH or C(O)O--A, wherein A is lower-alkyl, cycloalkyl or phenyl, and R3,R4 and R5 are either methyl or R... | 04/06/1999 |
| 5852014 | Condensed indole derivatives as 5HT4 -receptor antagonists Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.... | 12/22/1998 |
| 5846980 | N-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl methyl)-piperidine derivatives as antidepressants The invention relates to substituted nitrogenous heterocycles derivatives of general formula (I) ##STR1## in the racemic or optically pure form and/or in the form of cis/trans isomers, their pharmaceutically acceptable salts, and their use for p... | 12/08/1998 |
| 5843937 | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomer... | 12/01/1998 |
| 5807883 | 2-oxoindoline derivative Disclosed is a 2-oxoindoline derivative represented by the formula (I): ##STR1## wherein Ring A represents a benzene ring which is substituted in the 5-position or 6-position by a lower alkyl group or lower alkoxy group, R1 represents a ph... | 09/15/1998 |
| 5798379 | UCS1025 compounds UCS1025 compounds represented by the following formula (I): ##STR1## wherein R represents hydrogen or hydroxyl group, or tautomers or pharmacologically acceptable salts thereof.... | 08/25/1998 |
| 5789597 | Process for the preparation of compounds having ACE inhibitory action and intermediates in said process There is disclosed a process for the preparation of compounds having ACE inhibitory action of the formula ##STR1## wherein R has the meanings as in claim 1, wherein the stereospecific amino acid N-1-(S)-ethoxycarbonyl-3-phenylpropyl!-L-alanine is c... | 08/04/1998 |
| 5756320 | Bioactive substances K93-0711 I-1 and I-2 and process for production thereof Bioactive substances K93-0711 I-1 and I-2 having inhibitory action on IL-6 activity, are produced by culturing a microorganism belonging to the genus Streptomyces in a medium, whereby the bioactive substances K93-0711 I-1 and I-2 accumulate in the medium.... | 05/26/1998 |
| 5721245 | 4-3-indolyl!-1H-pyrrolone A compound of the formula ##STR1## wherein R is hydrogen or hydroxy, R1 and R2 taken together are a group of the formula --(CH2)m -- and R7 is hydrogen or R1 and R7 taken to... | 02/24/1998 |
| 5705498 | Piperidine derivatives as 5-HT4 receptor antagonists Compounds of formula (I): ##STR1## wherein Xg is O, S, SO, SO2, CH2, CH, N or NR wherein R is hydrogen or C1-6 alkyl; A is a saturated or unsaturated polymethylene chain of 2-4 carbon atoms; R1g | 01/06/1998 |
| 5693741 | Liquid molding compounds Low molecular weight resins that usually are aliphatic and that include crosslinking thermal functional groups are useful as liquid molding compounds for reaction injection molding or resin transfer molding. The compounds eliminate the need to handle solv... | 12/02/1997 |
| 5672618 | Protein kinase C inhibitors The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2.... | 09/30/1997 |
| 5668152 | Protein kinase C inhibitors The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2.... | 09/16/1997 |
| 5629427 | 2,7-diaminomitosene analogues The present invention relates to analogues of 2,7-diaminomitosene, a mitomycin C metabolite, useful as antitumor, antimicrobial and/or antiviral agents. These analogues involve functionalization of the N-2 nitrogen with organic groups.... | 05/13/1997 |
| 5627203 | Tricyclic oxime ethers The present invention relates to compounds of formula (I): ##STR1## wherein A, x, y, R1, R2 and R3 are as defined in the description. The compounds are useful for treating diseases requiring a selective serotonin reup... | 05/06/1997 |
| 5574060 | Selective inhibitors of biogenic amine transporters The present invention provides a compound having the structure: ##STR1## wherein X, Y, and Z are independently H, Cl, Br, F, OCH3, I, or an alkyl group having 1 to 6 carbon atoms; and R is ##STR2## wherein n is 0 to 6, X' and Y' are i... | 11/12/1996 |
| 5530018 | Meso-azanoradamantanes This invention relates to compounds of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein Z is selected from the group consisting of ##STR2## R1 is alkoxy of one to six carbon atoms; R2, R3 | 06/25/1996 |
| 5527800 | Tricyclic condensed heterocyclic compounds, their production and use A novel compound of the formula: ##STR1## wherein Ar represents an optionally substituted tricyclic condensed benzene ring group which includes at least one heterocyclic ring as a component ring; n represents an integer from 2 to 10; R1 re... | 06/18/1996 |
