Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 7332487 | Nitrogen-containing 5-membered ring compound The present invention is to provide an aliphatic nitrogen-containing 5-membered ring compound represented by the formula [I]: wherein symbols in the formula have the following meanings; ... | 02/19/2008 |
| 7132434 | Metalloproteinase inhibitors Compounds of the formula (I), useful as metal-loproteinase inhibitors, especially as inhibitors of MMP12 ... | 11/07/2006 |
| 6967215 | Tetrahydrocarbazoles, a process for the preparation of those compounds, and the use thereof Tetrahydrocarbazoles of formula where Q is —SO2—; —O—; or —(CO)—; X is —(CH)—; or —N—; m is from 1 to 3; t is 0 or 1 and the remaining substituents are as defined herein, are useful as an... | 11/22/2005 |
| 6699899 | Substituted acylhydroxamic acids and method of reducing TNF levels Imido and amido substituted acylhydroxamic acids which reduce the levels of TNF and inhibit phosphodiesterase in a mammal. A typical embodiment is (3-(1,3-dioxoisoindolin-2-yl)-3-(3-ethoxy-4-methoxyphenyl)propanoylamino)p ropanoate.... | 03/02/2004 |
| 6162822 | Bisimide compounds A compound of formula (I) ##STR1## in which: m, and n, which may be identical or different, represent 0 or 1, X and Y, which may be identical or different, represent hydrogen or halogen or alky, trihaloalkyl, alkoxy, hydroxyl, cyano, nitro, amino, alkylam... | 12/19/2000 |
| 6107345 | Benzocyclobutane compounds A compound of formula (I): ##STR1## wherein: Z1, Z2, Z3, Z4, which may be identical or different, represent a group as defined in the description, X represents oxygen, S(O)p, --(CH2)n | 08/22/2000 |
| 6030967 | Naphtholactams and lactones as bone morphogenetic protein active agents A compound of the formula: wherein Q is an optionally substituted carbon atom or N(O)p wherein p is 0 or 1; Y is an optionally substituted methylene group, S(O)q wherein q is an integer of 0 to 2, or an optionally substituted imino group; Z1 is a C1... | 02/29/2000 |
| 5786379 | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active adamantyl-substituted biaromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a')-(f'): ##STR2## and are useful for the treatment of a wide var... | 07/28/1998 |
| 5728709 | Alkyl and aralkyl-substituted pyrrolocarbazole derivatives that stimulate platelet production Described herein is a pyrrolocarbazole derivative and a pharmaceutically acceptable salt thereof having the following formula (I): ##STR1## wherein R1 is lower alkyl or aralkyl; R2 is hydrogen, substituted or unsubstituted lower... | 03/17/1998 |
| 5721267 | Chemotherapeutic pyrrolocarbazole derivatives Compounds represented by the Formula I: ##STR1## wherein: R1 is hydrogen or lower alkyl; R2 is heteroaryl; and R3 and R4 are independently hydrogen or lower alkyl; and the pharmaceutically acceptable salts thereof, a... | 02/24/1998 |
| 5693822 | Epoxy resins based on diaminobisimide compounds A method for the preparation of diaminobisimide compounds of the formula (I) which are substantially free of oligomers and are useful as curing agents in epoxy resin formulations: ##STR1## wherein Ar1 is an optionally substituted aromatic ... | 12/02/1997 |
| 5674432 | Photochromic naphthopyran compounds Described are novel reversible photochromic diaryl-3H-naphtho2,1-b!pyran compounds having a substituted or unsubstituted, five or six member heterocyclic ring fused to the g, i, or l side of the naphthopyran. The heterocyclic ring contains an oxygen or ... | 10/07/1997 |
| 5616666 | Bismaleimide compounds The invention relates to a bismaleimide compound of the formula (I) substantially free of oligomeric, amidic and uncyclized impurities: ##STR1## wherein Ar is an optionally substituted aromatic residue; and Ar' is an optionally substituted aromatic residu... | 04/01/1997 |
| 5523411 | Synthesis of mitomycin and its analogs The present invention relates to the synthesis of mitomycin and analogs thereof that are useful as anticancer antibiotics. The invention further relates to analogs of mitomycin, which can be prepared according to the methods of synthesis provided. The syn... | 06/04/1996 |
| 5514685 | Heteroatom-containing tricyclic compounds The invention concerns the compounds of formulae ##STR1## wherein the substituents have various significances. They can be prepared by various methods, e.g. acylation, reduction, alkylation, etc. They are indicated for use as pharmaceuticals, in part... | 05/07/1996 |
| 5451344 | Photochromic naphthopyran compounds Described are novel reversible photochromic diaryl-3H-naphtho[2,1-b]pyran compounds having a substituted or unsubstituted, five or six member heterocyclic ring fused to the g, i, or l side of the naphthopyran. The heterocyclic ring contains an oxygen or n... | 09/19/1995 |
| 5418232 | Diazabicycloalkene derivatives A compound of formula (I) possesses excellent potassium channel opening activity and is effective on various diseases arising from contractions of blood vessels, bronchial smooth muscles, etc., for example, ischemic heart diseases exemplified by angina pe... | 05/23/1995 |
| 5310909 | Photochromic compounds, a process for their preparation, and their use Compounds of the formula I ##STR1## in which X is O, S, SO, SO2 or NR13, R13 is, for example, methyl, and R1 to R12, independently of one another, are, for example, H, C1 -C12 | 05/10/1994 |
| 5296610 | N-substituted polyamide-imides An N-substituted polyamideimide essentially composed of identical or different repeating units of the formula I ##STR1## where R1 is one of the following tetravalent aromatic radicals ##STR2## and X is a bond or one of the following l... | 03/22/1994 |
| 5264538 | Cyclic poly(aryl ether) oligomers Cyclic poly(aryl ether) oligomers and mixtures thereof, and methods for the preparation thereof in a highly dilute reaction medium under reaction conditions favorable for ring closure at low degrees of polymerization. These oligomers are represented by th... | 11/23/1993 |
| 5242551 | Electron induced transformation of an isoimide to an n-imide and uses thereof A method of isomerizing an isoimide to an n-imide is described wherein an electron is supplied to the isoimide which induces the isomerization and wherein the isomerization is catalytic to the electron which remains available to initiate further isomeriza... | 09/07/1993 |
| 5166204 | Isoindole derivatives and salts thereof and antitumor agent comprising the same A novel isoindole derivative represented by general formula [1] or a salt thereof: ##STR1## which has an excellent antitumor activity and low toxicity.... | 11/24/1992 |
| 5106980 | Preparation of quinophthalones A process for the preparation of a quinophthalone of the formula ##STR1## in which X is hydrogen, chlorine or bromine and n is an integer from 1 to 4, by condensing 8-aminoquinaldine with a phthalic anhydride, optionally monosubstituted or polysubsti... | 04/21/1992 |
| 5068243 | Bicyclic tetrahydroxypyrrolizidine Novel bicyclic tetrahydroxylated pyrrolizidines are disclosed which are inhibitors of glycosidase enzymes. A preferred inhibitor is (1S,2R,6R,7S)-1,2,6,7-tetrahydroxypyrrolizidine. It is synthesized from D-glycero-D-talo-heptono-1,4-lactone and utilizes t... | 11/26/1991 |
| 5003078 | Synthesis of phthalonitrile resins containing ether and imide linkages Imide-containing phthalonitrile monomers are prepared from a phthalonitrile and an aromatic dianhydride. The monomer and a method for preparing the monomer is disclosed. These monomers are synthesized into heat resistant polymers and copolymers with aroma... | 03/26/1991 |
| 4999369 | Tetracyclic heterocyclic derivatives, pharmaceutical compositions and use The present invention relates to compounds of formula (I) ArCH2 R1 (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 29 carbon at... | 03/12/1991 |
| 4992460 | Bicyclic tetrahydroxylated pyrrolizidines Novel bicyclic tetrahydroxylated pyrrolizidines are disclosed which are inhibitors of glycosidase enzymes. A preferred inhibitor is 1, 2, 6, 7, 7ଲ-1,2,6,7-tetrahydroxypyrrolizidine. It is synthesized from D-gl... | 02/12/1991 |
| 4977158 | Dibenzoxepinon and dibenzothiepino-pyridinol or - pyrrotol derivatives with anti-depressant action The invention relates to novel tetracyclic compounds with an anti-depressant action, without neuroleptic or sedative side effects, of the general formula I ##STR1## and also functional derivatives hereof, wherein: R1 represents one or ... | 12/11/1990 |
| 4912107 | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them The invention concerns new pyrrolocarbazole derivatives of formula ##STR1## processes for their preparation, as well as medicaments containing these for the inhibition of protein kinases, such as protein kinase C, and thus for the prevention and/or t... | 03/27/1990 |
| 4874803 | Dianhydride coupled polymer stabilizers The present invention comprises reaction products resulting from the reaction of hydrazido-substituted or certain amino-substituted polymer stabilizers and cyclic dianhydrides, as well as the use of such products. The polymer stabilizers of the invention ... | 10/17/1989 |
| 4585876 | Novel xanthones and thioxanthones Novel xanthones and thioxanthones of the formula I ##STR1## in which A, X, Y, Z, E and E' are as defined in patent claim 1, are described. A is preferably --S-- and E and E' are preferably bonded in the ortho-position relative to one another. The com... | 04/29/1986 |
| 4528373 | Vinylacetylene-terminated polyimide derivatives Novel, unsaturated vinylacetylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new ... | 07/09/1985 |
| 4520198 | Vinylacetylene-terminated polyimide derivatives Novel, unsaturated vinylacteylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new ... | 05/28/1985 |
| 4517363 | Vinylacetylene-terminated polyimide derivatives Novel, unsaturated vinylacteylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new ... | 05/14/1985 |
| 4517364 | Vinylacetylene-terminated polyimide derivatives Novel, unsaturated vinylacteylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new ... | 05/14/1985 |
| 4435323 | Vinylacetylene-terminated polymide derivatives Novel, unsaturated vinylacetylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new ... | 03/06/1984 |
| 4405519 | Di-Acetylene-terminated polyimide derivatives Novel, unsaturated diacetylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new uns... | 09/20/1983 |
| 4405520 | Addition products of di-acetylene-terminated polymide derivatives and dienophiles having terminal maleimide grops Novel, unsaturated diacetylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new uns... | 09/20/1983 |
| 4405521 | Addition products of di-acetylene-terminated polyimide derivatives with a polyimide having terminal ethylenic groups Novel, unsaturated diacteylene-terminated polyimides and processes for their preparation are disclosed herein. There new polyimides are derivatives of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new uns... | 09/20/1983 |
| 4405786 | Addition products of di-acetylene-terminated polyimide derivatives and an dienophile having ethylene groups Novel, unsaturated diacteylene-terminated polyimides and processes for their preparation are disclosed herein. These new polyimides are derivaties of anhydride-terminated aromatic polyimides from which they can be prepared by amidation to provide new unsa... | 09/20/1983 |
