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Class 548/416 - Polycyclo ring system having the five-membered hetero ring as one of the cyclos


Subclass of Class 548 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the five-membered hetero ring is one of
No. of patents: 112
Last issue date: 08/23/2011


1      
NumberTitleIssue Date
8003807Device containing compound having indolocarbazole moiety and divalent linkage
An electronic device including a compound comprising at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage. ...
08/23/2011
7868186Device containing polymer having indolocarbazole- repeat unit and divalent linkage
An electronic device comprising a polymer comprising at least one type of repeat unit comprising at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage. ...
01/11/2011
7829727Device containing compound having indolocarbazole moiety and divalent linkage
An electronic device including a compound comprising at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage. ...
11/09/2010
7632954Substituted sym-triindole
A novel substituted Sym-triindole derivative that is applicable to a wide spectrum of uses, such as various electrification preventions, electrification controls, capacitors, batteries, chemical sensors, displays, organic EL materials, solar cells, photodiodes, phot...
12/15/2009
7585981Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof
The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation-reduction potential, high o...
09/08/2009
7423056Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are hexahydroazepinoi...
09/09/2008
7335470Compilations of nucleic acids and arrays and methods of using them
In one aspect the invention provides compilations of nucleic acids, articles of manufacture, e.g., arrays, and methods for the detection of chromosomal abnormalities, such as a chromosomal aneuploidies, deletions, amplifications, and the like, and the diagnosis or p...
02/26/2008
7332520Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
The present invention is directed to fused indole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved,...
02/19/2008
7323571Heterodimeric dye composition
This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful ...
01/29/2008
7316878Hydrazone-based charge transport materials having an unsaturated acyl group
Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the ...
01/08/2008
7312342Process for the preparation of (3-cyano-1h-indol-7-yl) (4-(4-fluorophenethyl) piperazin-1-yl)-methanone and salts thereof
The present invention relates to a process for the preparation of (3-cyano-1H-indol-7-yl)[4-(4-fluorophenethyl)piperazin-1-yl]-methanone and salts thereof, characterised in that an indole ester of the formula II in which R is as defined in Claim 1, is converter into...
12/25/2007
7301028Mitotic kinesin inhibitors
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which com...
11/27/2007
7291732Isomeric fused pyrrolocarbazoles and isoindolones
The present invention is directed to novel fused pyrrolocarbazoles and isoindolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directe...
11/06/2007
7282511Isatine derivatives with neurotrophic activity
The present invention relates to novel isatin derivatives, pharmaceutical compositions comprising the isatin derivatives of the invention, methods of preparing the isatin derivatives of the invention, their use in the treatment of neurodegenerative diseases and for ...
10/16/2007
7262215N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors
This invention relates to N-carbacycle monosubstituted indolocarbazole compounds. Furthermore, this invention relates to medicaments comprising N-carbacycle monosubstituted indolocarbazoles compounds and the use of such compounds for treating non-insulin dependent d...
08/28/2007
7256275Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation
This invention pertains to the field of combination oligomers, including the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, libraries and other compositions. ...
08/14/2007
72476512,7-substituted indoles
The present invention provides a compound of the formula: a pharmaceutically acceptable salt or a prodrug thereof, where R1, R2, R3, R4, and n are those defined herein....
07/24/2007
7241897Process for preparing cyanine dye labeling reagents
This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful ...
07/10/2007
7214703Pyrrolidinohydrochinazolines
Disclosed are compounds of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein the groups Ar1, Ar2, A, R1, R2, R3, E1
05/08/2007
7173047Benzo (f) insoindol derivatives and their use as ep4 receptor ligands
Compounds of formula (I) and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, i...
02/06/2007
7157421Piracetam and piracetam analog conjugate and a pharmaceutical composition for treatment of neuronal disorders
A compound of the formula where R1 is H, C1–C4 alkyl and OH; R2 in is H, C1–C4 alkyl and OH; R3 is H and C1–C4
01/02/2007
7122679Multicyclic compounds and the use thereof
The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for e...
10/17/2006
7118840Organophotoreceptor with a charge transport material having at least three linked hydrazone groups
Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the ...
10/10/2006
7115750Melanin concentrating hormone antagonist
A melanin-concentrating hormone antagonist which comprises a compound of the formula: wherein Ar1 is a cyclic group which may have substituents; X is a spacer having a main chain of 1 to 6...
10/03/2006
7115751Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof
The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation—reduction potential, high...
10/03/2006
7112391Electrophotographic organophotoreceptors with novel charge transport compounds
Charge transport compounds are described that have a multiple number of hydrazone-bridged (N,N-disubstituted)arylamine groups connected by a central bridging group. Examples of charge transport compounds of this invention are those having the following generic formu...
09/26/2006
7109229Methods and compounds for treating proliferative diseases
The compounds disclosed herein are indolocarbazoles of Formula (I), which are potent CDK4 inhibitors, and are useful in the treatment of cell proliferative disorders, including cancer. Formula (I). ...
09/19/2006
7091229Tricyclic lactam and sultam derivatives and their use as histone deacetylase inhibitors
A compound of formula (I) wherein A and B are optionally substituted cyclohexenyl or phenyl groups, X is carbonyl or sulfonyl, and Y is 5–7 atoms-linker, is useful as histone deacetylase inhibitors, particularl...
08/15/2006
7081536Isoxazoline derivatives as P N ligands
The invention relates to novel ligands of the phosphanylbenzothiophenyl-dihydroisoxazoline, phosphanyl-dihydrooxazolyl-indole and phosphanyl-dihydrooxazolyl-benzofuran type, especially compounds of formula I and ...
07/25/2006
7067622Method of the solid phase synthesis of pyrrole-imidazole polyamide
It is intended to provide a method of producing a pyrrole-imidazole polyamide whereby a longer pyrrole-imidazole polyamide can be conveniently synthesized and a peptide (protein) can be easily transferred. According to this method, a pyrrole-imidazole polyamide havi...
06/27/2006
7045360Method for analysis of reaction products
The present invention provides methods, compounds, and kits useful in the analysis of reaction products and components of reaction mixtures, and in certain embodiments for the rapid and simultaneous determination of enantiomeric ratios, percent conversions, and abso...
05/16/2006
7026489Ketol fatty acid derivative and plant growth regulating agents
α-Ketol unsaturated fatty acid derivatives represented by the following formula (1), α-ketol unsaturated fatty acid amide derivatives represented by the following formula (6), and plant growth regulators containing, as the active ingredient, at least one of these ...
04/11/2006
7026338Pharmaceutical nitrones
Pharmaceutical nitrone comprise condensates of an N-hydroxylamine and a physiological aldehyde, providing improved delivery and absorption, enhanced stability and reduced toxicity. Preferred physiological aldehydes are subject to endogenous cellular uptake transport...
04/11/2006
6916893Polymerization-active transition metal complexes having bulky ligand systems
Transition metal complexes having bulky ligand systems and the formula (I) where R2, R4 are C4-C16-heteroaryl or C6-C16-aryl bearing C...
07/12/2005
6906198Antipicornaviral compounds, their preparation and use
Peptido and peptidomimetic compounds of the formula: wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compou...
06/14/2005
6887634Electrophotographic organophotoreceptors with novel charge transport compounds
Charge transport compounds are described that have a multiple number of hydrazone-bridged (N,N-disubstituted)arylamine groups connected by a central bridging group. Examples of charge transport compounds of this invention are those having the following generic formu...
05/03/2005
6872746Isomeric fused pyrrolocarbazoles and isoindolones
The present invention is directed to novel fused pyrrolocarbazoles and isoindolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directe...
03/29/2005
6861441Use of EP4 receptor ligands in the treatment of neuropathic pain and colon cancer
The present invention relates to the use of an EP4 receptor ligand in the manufacture of a medicament for use in the treatment of neuropathic pain, colon cancer, migraine, and for increasing the latency of HIV infection. ...
03/01/2005
6835514Hydrazone-based charge transport compounds
Improved organophotoreceptor include: (a) a charge transport compound having the formula where R1 has a structure of: ...
12/28/2004
6770638Tetrahydroindolone and purine derivatives linked to arylpiperazines
Pharmaceutical composite compositions comprising tetrahydroindolones linked to arylpiperazines and derivatives thereof are disclosed. Specifically, composite compositions useful in treating anti-psychotic disorders are disclosed. The composite compositions disclosed...
08/03/2004
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