Bizarre Patents
A simulation environment for the sport of boxing utilizing a robotic machine interface system which carries a person.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7375248 | Inhibitors of matrix metalloproteinase Compounds of formula (I): wherein R1 represents optionally substituted C4-12 alkyl, optionally substituted C2-6alkylaryl, or optionally substituted 5- or 6-membered aryl or hete... | 05/20/2008 |
| 7250438 | Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a nitro group. Screening data shows antimicrobial activity against vario... | 07/31/2007 |
| 7122677 | NK1 antagonists A NK1 antagonist having the formula (I), wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5... | 10/17/2006 |
| 6960474 | Method for the treatment of a condition remediable by administration of a selective androgen receptor modulator Selective androgen receptor modulators (SARMs) having antagonist activity in hormone-dependent tumors while exhibiting no activity or agonist activity against other nontumor tissues containing the androgen receptor as well as methods for identifying, designing and u... | 11/01/2005 |
| 6894005 | Herbicides Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomer of those compounds, are suitable for use as herbicides. ... | 05/17/2005 |
| 6818664 | Angiogenesis inhibitor A compound represented by the following formula (I) or a salt thereof and a medicament such as an angiogenesis inhibitor and an antitumor agent which comprises said compound or a physiologically acceptable salt thereof as an active ingredient. | 11/16/2004 |
| 6630594 | Methods of making substituted phenylketoenols The present invention provides methods of making substituted phenylketoenols of the general formula I, ##STR1## wherein V, W, X, Y, Z and Het are as defined herein. The compounds have pesticidal and herbicidal activity.... | 10/07/2003 |
| 6608068 | Indoline derivatives This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including contraception and treatment of benign or malignant neoplastic dise... | 08/19/2003 |
| 6608211 | Substituted phenyl ketoenols The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which A, B, G, X, Y, Z and W are each as defined in the description, to processes and intermediates for their preparation and to their use as pesticides and ... | 08/19/2003 |
| 6555567 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides The invention concerns substituted spiro heterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives depicted by the formula: ##STR1## X is alkyl, halogen or alkoxy; Y is hydrogen, alkyl, halogen, alkoxy or alkyl halide; Z is alkyl, halogen or alkoxy; n is 0,... | 04/29/2003 |
| 6391907 | Indoline derivatives This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including contraception and treatment of benign or malignant neoplastic dise... | 05/21/2002 |
| 6358887 | 2-Phenyl-substituted heterocyclic 1,3-ketonols as herbicides and pesticides The present invention relates to new compounds of the formula (I) ##STR1## in which X, Y and Z have the meanings given in the description and Het represents one of the groups ##STR2## in which A, B, D and G have the meanings given in the description, a plurali... | 03/19/2002 |
| 6358750 | Spiro[pyrrolidine-2,3'-oxindole] compounds and method of use The invention provides spiro[pyrrolidine-2,3'-oxindole] compounds and libraries of these compounds produced by the stereo- and regio-selective reaction of variously substituted isatins, -amino acids, and dipolarophiles (e.g., trans-chalcones, acryl... | 03/19/2002 |
| 6288102 | Substituted phenylketoenols and their use as pesticides and herbicides The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which Het represents one of the groups ##STR2## and G, V, W, X, Y and Z are each as defined in the description, to processes and intermediates for their pre... | 09/11/2001 |
| 6207697 | Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa The present application describes inhibitors of factor Xa of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein W, W1, W2, and W3 may be N or C and J, Ja, and Jb combine to ... | 03/27/2001 |
| 6200932 | Phenyl-substituted cyclic ketoenol The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which A, B, G, X, Y, Z and n are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and her... | 03/13/2001 |
| 6166209 | Piperidine derivatives The present invention relates to compounds of the formula ##STR1## wherein X is --O-- or --CH2 --; Y is --C(O)--, --(CH2)n -- or --N(CH3)--; n is 1 or 2 or X and Y taken together are --CH.dbd.CH-- Z is --NH--, --CH | 12/26/2000 |
| 6114540 | Spiro[pyrrolidine-2,3'-oxindole] compounds and methods of use The invention provides spiro[pyrrolidine-2,3'-oxindole] compounds produced by the stereo- and regio-selective reaction of variously substituted isatins, -amino acids, and dipolarophiles (e.g., trans-chalcones, acrylate esters, or vinyl oxindoles).... | 09/05/2000 |
| 6110872 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides The invention relates to new phenyl-substituted cyclic ketoenols of the formula (I) in which Het represents one of the groups ##STR1## wherein A, B, D, G, X, Y and Z have the meaning given in the description, several processes and intermediate produc... | 08/29/2000 |
| 6060469 | Spiro-piperidine derivatives and their use as tachykinin antagonists The present invention relates to compounds of formula (I), ##STR1## wherein R1 represents halogen, hydroxy, C1-6 alkyl group optionally substituted by one or three fluorine atoms, C1-6 alkoxy group optionally substitu... | 05/09/2000 |
| 6015912 | Spirocyclic containing hydroxamic acids useful as metalloprotease inhibitors The invention provides compounds of formula ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibito... | 01/18/2000 |
| 6013652 | Spiro-substituted azacycles as neurokinin antagonists Disclosed are spiro-substituted azacycles of formula I are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.... | 01/11/2000 |
| 5981567 | Substituted spiroheterocyclic 1h-3-aryl-pyrrolidine-2,4-dione derivatives and their use as pesticides The invention concerns substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives of formula (I) in which A and B together with the carbon atom to which they are bound, are an unsubstituted or substituted 5- or 6-membered ring including at l... | 11/09/1999 |
| 5948807 | Spiroindanamines and Spiroindanimides Compounds of formula I: ##STR1## wherein R1, R2, W, X, Y and Z have any of the values defined in the specification, and their pharmaceutically acceptable salts, are inhibitors of monoamine re-uptake and are useful for treating d... | 09/07/1999 |
| 5849780 | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present The invention relates to 1-Benzenesulfonyl-1,3-dihydroindol-2-one derivatives of the formula ##STR1## and their salts, where appropriate, to their preparation and to pharmaceutical compositions in which they are present. These compounds have an ... | 12/15/1998 |
| 5830825 | 3-aryl-tetronic acid derivatives, the production thereof and the use thereof as antiparasitic agents The present invention relates to new 3-aryl-4-hydroxy-Ɗ3 -dihydrofuranone derivatives of the formula (I) ##STR1## in which A and B together with the carbon atom to which they are bonded form an unsubstituted or substituted 5- to 7-membere... | 11/03/1998 |
| 5763471 | Melatoninergic agonist spiro indolepyrrolidine! derivatives, process for their preparation and their use as medicinal products The present invention relates to spiro3H-indole-3(2H),3'-pyrrolidine! derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular... | 06/09/1998 |
| 5726322 | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present The invention relates to 1-Benzenesulfonyl-1,3-dihydroindol-2-one derivatives of the formula ##STR1## and their salts, where appropriate, to their preparation and to pharmaceutical compositions in which they are present. These compounds have an ... | 03/10/1998 |
| 5723625 | Process for the production of specific isomer mixtures from oxindole alkaloids To produce defined isomer mixtures of compounds with spirocyclic beta-aminocarboxyl and/or beta-aminocarbonyl systems the invention supposes that they be dissolved in solvents which have good dissolving power for these compounds, whose relative permittivi... | 03/03/1998 |
| 5696145 | 1-benzyl-1,3-dihydroindol-2-one derivatives, their preparation and the pharmaceutical compositions in which they are present The present invention relates to 1-benzyl-1,3-dihydroindol-2-one derivatives of the formula ##STR1## to their preparation and to the pharmaceutical compositions in which they are present. These derivatives have an affinity for the vasopressin and ... | 12/09/1997 |
| 5688826 | Excitatory amino acid derivatives Compounds for formula I ##STR1## in which X represents O, NRa, S, SO or SO2 and R is as defined in the specification; and non-toxic metabolically labile esters or amides thereof; and pharmaceutically acceptable salts thereof are... | 11/18/1997 |
| 5686624 | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present The invention relates to 1-Benzenesulfonyl-1,3-dihydroindol-2-one derivatives of the formula ##STR1## and their salts, where appropriate, to their preparation and to pharmaceutical compositions in which they are present. These compounds have an ... | 11/11/1997 |
| 5585378 | Composition containing an oxoindole compound The present invention relates to an oxindole compound having the formula 5-cyclohexyl-1,3-dihydro-1-[2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2H-in dol-2-one for the prevention or treatment of cognitive dysfunctions.... | 12/17/1996 |
| 5462913 | Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives The invention relates to new 1-H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) ##STR1## in which A and B together with the carbon atom to which they are bonded represent a substituted cycle, X represents alkyl, halogen or alkoxy, Y repr... | 10/31/1995 |
| 5294635 | Heterocyclic compounds as aldose reductase inhibitors Certain spirocyclic heterocyclic compounds, and their pharmaceutically-acceptable salts, are inhibitors of the aldose reductase enzyme, and so are useful for the control of diabetic complications.... | 03/15/1994 |
| 5250733 | Benzylideneindene compounds and electrophotographic photoconductor using the same Benzylideneindene compounds, which are useful not only as the photoconductive material for electrophotography, but also as a charge transporting material employed in a function-separating type photoconductor in which an organic or inorganic pigment is use... | 10/05/1993 |
| 5216020 | Substituted 4,5-dihydrothieno(2,3-b)thiophene-2-sulfonamides and 6,6-dioxides thereof Substituted 4,5-dihydrothieno[2,3-b]thiophene-2-sulfonamides and 6,6-dioxides thereof are topically effective carbonic anhydrase inhibitors useful in the treatment of ocular hypertension and glaucoma associated therewith.... | 06/01/1993 |
| 5179119 | 1,3-dihydro-1-(pyridinylamino)-2H-indol-1-ones and intermediates for the preparation thereof This invention relates to 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones of the formula ##STR1## where R1, R2 and R3 are independently hydrogen, loweralkyl, aryl, arylloweralkyl or heteroarylloweralkyl selected from t... | 01/12/1993 |
| 5149823 | Sulfonamide substituted spirodilactams A novel class of sulfonamoyl-substituted 1,6-diaza[4.4]spirodilactams, having a sulfonamoyl substituent on the hydrocarbyl group attached to each spiro ring nitrogen atom, is useful for the preparation of polymers, including polyamides and as latent curin... | 09/22/1992 |
| 5103001 | Spirodilactams Novel 1,6-diaza [4.4] spirodilactams having heterocyclic-containing substituents on each spiro ring nitrogen atom are produced by reaction of a heterocyclic-substituted primary amine compound and a spirodilactam precursor selected from 4-oxoheptanedioic a... | 04/07/1992 |
