Class 548/345.1 - Cycloaliphatic ring bonded directly to the diazole ring

Subclass of Class 548 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the diazole ring is bonded directly to
No. of patents: 90
Last issue date: 04/25/2006

«First «Previous1 2 3 Next»Last»

Number	Title	Issue Date
7034034	Substituted 2-cyclohexyl-4-phenyl-1H-imidazole derivatives Substituted 2-cyclohexyl-4-phenyl-1H-imidazole derivatives capable of modulating NPY5 receptor activity, are provided. Such compounds may be used to modulate NPY binding to NPY5 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety...	04/25/2006
6878734	Gastrin and cholecystokinin receptor ligands(II) Ligands for the gastrin and cholecystokinin (CCK) receptors are provided, together with methods for preparing such ligands, and compounds which are useful intermediates in such methods. Pharmaceutical compositions comprising such ligands, methods for preparing such ...	04/12/2005
6794405	Alicyclic imidazoles as H3 agents Alicyclic imidazole compounds; pharmaceutically active compositions containing such compounds; and the use of such compounds in formulations for the control or prevention of disease states in which histamine H3 receptors are involved, such as allergy, inf...	09/21/2004
6603019	1-imidazolyl substituted tetrahydronaphthalene derivatives as inhibitors of eytochrome P450RAI Compounds having Formula 4 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids ##STR1##...	08/05/2003
6525082	Apoptosis inducer A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance....	02/25/2003
6518305	Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases Disclosed are compounds of the formula: ##STR1## which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caus...	02/11/2003
6479530	Imidazole derivatives having affinity for 댒 receptors Imidazole derivatives of formula I ##STR1## wherein n is 0 or 1, R1 is hydrogen or C1 -C4 -alkyl, R2 is hydrogen or R2 and R3 together form a double bond, R3 is hydrogen or C	11/12/2002
6426360	4,5-substituted imidazolyl compounds for the treatment of inflammation A class of compounds is described for treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula ##STR1## wherein R1 is selected from lower alkyl, lower haloalkyl, lower hydroxyalkyl, ...	07/30/2002
6417218	Substituted imidazoles, their preparation and use A class of substituted imidazole compounds of formula I ##STR1## methods for their preparation, pharmaceutical compositions comprising them and use thereof in the treatment of disorders related to the histamine H3 receptor are disclosed. More particularly...	07/09/2002
6362211	Polycyclic indanylimidazoles with alpha2 adrenergic activity A compound of formula I ##STR1## wherein R1 to R3, --A--, m and t are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha2 adrenergic agent....	03/26/2002
6316380	Catalyst system comprising transition metal and imidazoline-2-ylidene or imidazolidine-2-ylidene This invention provides a catalyst system useful in many coupling reactions, such as Suzuki, Kumada, Heck, and amination reactions. The catalyst system of the present invention makes use of N-heterocyclic carbenes or their protonated salts. The compositio...	11/13/2001
6313311	Imidazole derivatives having affinity for alpha2 receptors Imidazole derivatives of formula (I) ##STR1## wherein n is 0 or 1, R1 is hydrogen or C1 -C4 -alkyl, R2 is hydrogen or R2 and R3 together form a double bond, R3 is hydrogen or C	11/06/2001
6177575	Process for manufacture of imidazoles Imidazoles may be manufactured by reacting a glyoxal, ammonia, an aldehyde, and optionally a primary amine, in the presence of a Bronsted acid whose pKa is approximately equal to the pKa of the ammonium cation of the primary amine, or if the primary amine...	01/23/2001
6124465	Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ...	09/26/2000
6121273	N-linked sulfonamides of heterocyclic thioesters This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin pr...	09/19/2000
6013662	Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ...	01/11/2000
6008240	2-(1H-4(5)-imidazoyl) cyclopropyl derivatives The present invention provides compounds having H3 histamine receptor antagonist activity of the general formula: ##STR1## R2 is a hydrogen or a methyl or ethyl group; R3 is a hydrogen or a methyl or ethyl group; n is...	12/28/1999
5990317	2-(1H-4(5)-imidazoyl) cyclopropyl compounds The present invention provides compounds having H3 histamine receptor antagonist activity of formula (1.0) wherein R2 is a hydrogen or a methyl or ethyl group; R3 is a hydrogen or a methyl or ethyl group; n is 0, 1, 2, 3, ...	11/23/1999
5977377	Process for producing N-alkylimidazole Disclosed is a process for producing an N-alkylimidazole which comprises reacting an imidazole with an N-alkylating agent in an organic solvent in the presence of alkali particles having a specific surface area of 0.6 M2 /g or larger....	11/02/1999
5877326	Aqueous phase process for preparing N-substituted imidazoles A process for preparing substituted imidazoles of the formula I ##STR1## R1, R2 and R3 are identical or different and are each hydrogen, halogen, NO2, CN or a C1 -C20 -hydrocarbon radi...	03/02/1999
5719291	Cyclohexane derivatives Compounds of the formula ##STR1## which have antifungal activity....	02/17/1998
5658938	Substituted 1H-imidazoles Substituted 4-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazoles and 4-(2,3-dihydro-1H-inden-1-yl)-1H-imidazoles, their optical isomers and their racemic mixtures, their salts, methods for preparing them and therapeutic compositions containing them. These ...	08/19/1997
5652258	2-(4-imidazoyl) cyclopropyl derivatives The present invention provides compounds having H3 histamine receptor antagonist activity of the general formula: ##STR1## where X is H, A is --CH2 CH2 --, --COCH2 --, --CONH--, --CON(CH3)--, --C...	07/29/1997
5646293	Preparation of N-alkenylazoles A process for preparing N-alkenylazoles of the general formula I ##STR1## where X is CH--R6 or nitrogen, R1 and R2 are hydrogen or C1 - to C8 -alkyl, R3,R4,R5 and R6	07/08/1997
5620999	Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation A class of imidazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II ##STR1## wherein R1 is selected from lower alkyl, lower haloalkyl,...	04/15/1997
5366984	Methyl ଱-arylacrylates substituted by a heterocyclic radical and their use Methyl ଱-arylacrylates substituted by a heterocyclic radical and having the general formula ##STR1## where R is alkyl, alkenyl, haloalkyl, cycloalkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl, halogen or aryl, the aromatic ring being unsubstituted...	11/22/1994
5312927	Preparation of imidazoles The present invention relates to preparation of imidazoles which are useful as pharmaceutical and agricultural chemicals. Specifically, the present invention relates to a process for preparing imidazoles of the formula (I): ##STR1## which compri...	05/17/1994
5292887	Substituted imidazole derivatives and their preparation and use Compounds of the formula: ##STR1## wherein X is --CH2 -- or ##STR2## R1 is H, C1-5 -alkyl or benzyl, which can be substituted or unsubstituted R2 is H, C1-4 -alkyl, OH or C1-3 -al...	03/08/1994
5233048	Triarylmethane color formers Color formers of the general formula ##STR1## in which --independently of one another-- R1 and R2 are hydrogen, halogen, alkyl, aralkyl etc., Y1 and Y2 are alkyl, aryl, cycloalkyl or aralkyl, X1 is al...	08/03/1993
5227401	Ethynyl alanine amino diol compounds for treatment of hypertension Compounds characterized generally as ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I ##STR1## wherein A is selected from CO and SO2	07/13/1993
5225548	Indophenol dyes and thermal transfer thereof Indophenol dyes of the formula ##STR1## where X is nitrogen or the radical CH, Q is a five-membered heterocyclic radical, and K is a radical of an aniline, aminonaphthalene, aminoquinoline or aminothiazole derivative, and the radical A can be benzofused, ...	07/06/1993
5207816	Cyclohexenone derivatives and their use for controlling undesirable plant growth Cyclohexenone derivatives of the formula ##STR1## where R1 is alkyl, R2 is alkyl, unsubstituted or halogen-substituted alkenyl or alkynyl, X is a substituted or unsubstituted five-membered heteroaromatic radical, and Z is hydrog...	05/04/1993
5204364	N-imidazolyl- and N-imidazolylmethyl-derivatives of substituted bicyclic compounds The present invention relates to new N-imidazolyl and N-imidazolylmethyl derivatives of bicyclic compounds having the general formula (I) ##STR1## Wherein A is a ࣙCR3 or >CHR3 group, in which R3 is hydrogen or C	04/20/1993
5194623	Azlactone based photographic reagents Novel compounds derived from azlactones act as precursors for photographically active groups. The active groups are released at an appropriate time in the use of photographic and photothermographic systems....	03/16/1993
5191086	Imidazole and benzimidazole derivatives Novel angiotensin-II receptor antagonists are disclosed having the general formula ##STR1## wherein R1, R2, R3, R4, R5, W and X are as defined herein....	03/02/1993
5190942	Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives Novel compounds are disclosed having the formula ##STR1## wherein X, Y, R1, R2, R3, R4, and R5 are as defined herein. These compounds inhibit the action of angiotensin II and are useful, therefor...	03/02/1993
5179210	Preparation of N-substituted imidazoles A process for preparing N-substituted imidazoles of the formula I ##STR1## where R1 is C1 -C20 -alkyl, C2 -C20 -alkenyl, C2 -C20 -alkynyl, C2 -C20 -alkoxyal...	01/12/1993
5177099	Dichloro-substituted imidazole derivatives as antifungal agents Dichloro-substituted 1-(5H-dibenzo[a,d]cyclohepten-5-yl)-1H-imidazole comnds of formula (I), in which --X-- is either --CH2 --CH2 -- or --CH.dbd.CH--, and their pharmaceutically acceptable addition salts, preferably the nitric acid ...	01/05/1993
5175151	Antiviral compounds and antihypertensive compounds Compounds useful as antihypertensive agents, or antiviral agents against DNA containing viruses, such as herpes group viruses, are disclosed. The compounds are represented by Formula 1.0: ##STR1## and their pharmaceutically acceptable salts and solva...	12/29/1992
5162541	Transfer hydrogenolysis of alkylheteroaryl halo-containing compounds A method for dehalogenating a compound of the generalized structure ##STR1## is disclosed where: R1, R2 and R3 independently are hydrogen or methyl or R1 and R3 taken together represent methylene...	11/10/1992

«First «Previous1 2 3 Next»Last»

PatentStorm

Celebrity Inventors

PatentStorm News

Class 548/345.1 - Cycloaliphatic ring bonded directly to the diazole ring