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| Number | Title | Issue Date |
| 7745635 | Energetic ionic salts The invention provides a) a method for making improved ionic halide salts, e.g., 1-methyl-4-amino-1,2,4-triazolium iodide and b) a method for making energetic ionic salts, e.g., 1-methyl-4-amino-1,2,4-triazolium nitrate, in high yield and purity from triazolium prec... | 06/29/2010 |
| 7423157 | Substituted benzimidazoles and their use for inducing apoptosis The invention relates to compounds of formula (I) wherein R represents aryl or heteroaryl, X is a bond, a carbonyl group, a derivative of a carbonyl group, an ethylene group or an ethylenecarbonyl group, R1 is op... | 09/09/2008 |
| 7407972 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thro... | 08/05/2008 |
| 7060718 | Arylsulfonanilide ureas The invention provides compounds, compositions and methods relating to novel arylsulfonanilide derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particular... | 06/13/2006 |
| 7045635 | Process for the synthesis of 4-amino-4H-1,2,4-triazole An improved process for synthesizing 4-amino-1,2,4-triazole. Hydrazine hydrate solution is mixed into ethyl formate, ethanol, and an acidic ion exchange resin in a condenser. The solution is held at 75 degrees Celsius until no more liquid exits the condenser. The so... | 05/16/2006 |
| 6743817 | Substituted fused pyrroleimines and pyrazoleimines Disclosed are compounds of the formula and the pharmaceutically acceptable salts thereof wherein R, Ar, A, n, R1 and R2 are defined herein. These compounds are highly selective agonists, antagonists... | 06/01/2004 |
| 6608093 | Pesticidal 1-polyarylpyrazoles A compound of formula (I): ##STR1## compositions containing them and methods of use to control pests.... | 08/19/2003 |
| 6509473 | Energetic triazolium salts New energetic salts of 1,2,4-triazole; 3,4,5-triamino-1,2,4-triazole and of 4-amino 1,2,4-triazole were synthesized, characterized and their thermal and safety properties evaluated as possible new propellant ingredients. Energetic anions, including the ni... | 01/21/2003 |
| 6504033 | Process for the preparation of 4-amino-1,2,4-Triazole The present invention relates to a process for the preparation of products of formula (1): ##STR1## in which R denotes H or an alkyl group containing from 1 to 10 carbon atoms, it being possible for this alkyl group to be substituted by one or more a... | 01/07/2003 |
| 6096774 | Energetic nitramine-linked azoles and hydroxylammonium salts as oxidizers, intiators and gas generators Novel compounds are provided having the structural formula R[--N(NO2)--L--R1 ]n wherein R, L, R1 and n are defined herein. The compounds are useful in a variety of contexts, but are primarily to be used as high ... | 08/01/2000 |
| 6080770 | Modulators of molecules with phosphotyrosine recognition units The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their... | 06/27/2000 |
| 6077813 | Substituted aromatic thiocarboxylic acid amides and their use as herbicides There is disclosed substituted thiocarboxamides of the general formula (I) ##STR1## , wherein Z, R1, R2 and R3 are as defined by the specification, which are useful herbicidal agents.... | 06/20/2000 |
| 6040456 | Process for the preparation of 4-amino-1,2,4-triazole The present invention relates to a process for the preparation of products of formula (1): ##STR1## in which R denotes H or an alkyl group containing from 1 to 10 carbon atoms, it being possible for this alkyl group to be substituted by one or m... | 03/21/2000 |
| 5962436 | Fungicidal cyclic amides Cyclic amides, including triazole containing cyclic amides, their N-oxides, agriculturally-suitable salts and compositions, and their methods of use as fungicides.... | 10/05/1999 |
| 5955607 | Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and pharmaceutical preparations comprising them Compounds of the formula I ##STR1## having the meanings of the substituents indicated in the claims are outstandingly efficacious substances for producing medicaments for the prophylaxis and for the therapy of cardiovascular disorders, in particular ... | 09/21/1999 |
| 5935973 | Heterocyclcarboxamide derivatives and their use as therapeutic agents Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof in which A is methylene or O; B is methylene or O; g is 0,1,2,3 or 4; R1 is an optional substituent; U is an alkylene chain optionally substituted by one or more... | 08/10/1999 |
| 5922744 | Ethane-1-2-diamine derivatives and tachykinin antagonists The present invention provides a compound of formula: ##STR1## wherein R, R1, R2, R3, R4, R5, R6a and R6b are defined herein or a pharmaceutically acceptable salt thereof, a... | 07/13/1999 |
| 5912355 | Chiral synthesis of tertiary alcohols with a hydrolase Method of preparing an optically active compound of formula, wherein R and R1 are independently alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, aryl, aralkyl, a heterocyclic group or a C1 -C4 alkyl-heterocycle, e... | 06/15/1999 |
| 5750545 | Triazole derivative and pharmaceutical use thereof An agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, an agent for the prophylaxis and treatment of allergic diseases, an agent for the prophylaxis and treatment of eosinophil-related diseases and an eosi... | 05/12/1998 |
| 5496480 | Ashless dispersants comprising reaction product of acylating agent and aminoguanidine Ashless dispersants are formed using polymers of propylene characterized in that they are liquid substantially linear polymers, they have stereo-irregularity in the polymer chain, at least 60 mol percent of the polymer has a terminal vinylidene group and,... | 03/05/1996 |
| 5484936 | Processes for the preparation of 1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol derivatives The invention provides a regiospecific process for the preparation of 1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol derivatives comprising reacting an oxirane acid salt or an oxirane, under acidic conditions, with 4H-4-amino-1,2,4-triazole. The process is parti... | 01/16/1996 |
| 5482954 | Signal transduction inhibitor triazole and diazole compounds A discovery underlying this invention is the concordance between particular cellular signaling mechanisms and cancer cell growth and metastasis. It has now been discovered that certain compounds inhibit the signal transduction required for the maintenance... | 01/09/1996 |
| 5391561 | Halopropargyl compounds, compositions, uses and processes of preparation Compounds of the formula ##STR1## wherein A is selected from the group consisting of hydrogen, alkyl, aryl, and heterocyclic; Y and Z are independently selected from the group consisting of O, S, and N--R; R is selected from the group consisting of h... | 02/21/1995 |
| 5359078 | Signal transduction inhibitor compounds A compound having the formula: Y--(CH2)p --Ar11 --X--Ar12 wherein: p is an integer of from 0 to 4; Ar11 and Ar12 are each aromatic moieties independently selected from the group consisting of phenyl,... | 10/25/1994 |
| 5221676 | 7-substituted quinolones and naphthyridones as antibacterial agents 7-Substituted quinolones and naphthyridones are described as antibacterial agents as well as a process for their manufacture, compositions therefor, wherein the 7-substituent is a pyrrolidine ring substituted at the 3-position by a substituted aromatic hy... | 06/22/1993 |
| 5110986 | Synthesis of N-t-alkyl-1,2-diacylhydrazines This application relates to a process for preparing a N-t-alkyl-1,2-diacylhydrazine by reacting a 1,3,4-oxadiazole with a tertiary alkyl cation precursor in the presence of a strong acid catalyst. Preferably, the 1,3,4-oxadiazole is a 2,5-disubstituted-1,... | 05/05/1992 |
| 5099028 | Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivatives A process for preparing a 4-amino-1,2,4-(4H)triazole derivative compositions having the formula ##STR1## wherein R is hydrogen or an alkyl group containing from 1 to about 10 carbon atoms, which alkyl group can be additionally substituted by one or ... | 03/24/1992 |
| 5070098 | Substituted pyrazoline derivatives, pesticidal compositions and use This invention relates to novel substituted pyrazoline derivatives of the general formula ##STR1## processes for their preparation and their use as pesticides.... | 12/03/1991 |
| 5051517 | Process for the preparation of herbicidally active 3-amino-5-aminocarbonyl-1,2,4-triazoles 3-amino-5-amino-carbonyl-1,2,4-triazoles of the formula ##STR1## are obtained in good yields and in high purity when a chloroformadine hydrochloride of the formula ##STR2## are reacted with an oxamohydrazide of the formula ##STR3## Thi... | 09/24/1991 |
| 5021081 | Herbicidal substituted triazoles Herbicidal substituted triazoles of the formula ##STR1## in which R1 and R2 independently of one another each stands for hydrogen, alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, halogenoalkinyl, alkoxyalkyl, cycloalkyl... | 06/04/1991 |
| 4962119 | Triazole derivatives of fenamates as antiinflammatory agents The present invention is novel compounds which are 1,2,4-triazoles, derivatives of fenamates and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use thereof. The invention compounds are now found to... | 10/09/1990 |
| 4957935 | Phenyltriazole derivative and insecticide A phenyltriazole compound having the formula: ##STR1## wherein X is a lower alkyl group having all or a part of hydrogen atoms substituted by fluorine atoms, and each of R1 and R2 which may be the same or different, is a hydroge... | 09/18/1990 |
| 4925864 | Phenyltriazole derivative and insecticide A phenyltriazole derivative of the formula: ##STR1## wherein X is a halogen atom, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, a nitro group, a phenoxy group, an amino group, a cyano group, a 1-pyrrolyl group or a halogen-subst... | 05/15/1990 |
| 4879327 | New phosphorous acid salts, compositions containing them, and their application as fireproofing agents The invention relates to amine salts of phosphorous acid having a structure of the s-triazine, 1,2,4-triazole, benzimidazole, heptazine, pyrimidine, or piperazine type which may be combined with a polyhydroxylated compound as fireproofing agents for plast... | 11/07/1989 |
| 4734257 | Method of inhibiting corrosion of nonferrous metals in aqueous systems using 3-amino-5-(ω-hydroxyalkyl)-1,2,4-triazoles The present invention provides a method of inhibiting the corrosion of nonferrous metals using an anticorrosive agent selected from 3-amino-5-(ω-hydroxy-n-alkyl)-1,2,4-triazoles having the general formula: ##STR1## wherein x is an integer in th... | 03/29/1988 |
| 4695567 | Pyrrolobenzimidazoles, pharmaceutical compositions containing them and method of using them to treat certain heart and circulatory diseases The present invention provided pyrrolobenzimidazoles or tautomer thereof, of the general formula: ##STR1## wherein R1 is hydrogen, C1 -C6 alkyl, C2 -C6 alkenyl or C3 -C7 cyc... | 09/22/1987 |
| 4656176 | 2-thiazolyl, oxazolyl, triazolyl and thiadiazolyl alkylamino-3-nitro-heterocyclic compounds 2,3-Unsaturated nitrogen-containing heterocyclic compounds with a 3-nitro group and a 2-heterocyclyl alkylamino group. The alkyl group of 2-position substituents is preferably interrupted by sulfur or oxygen. The compounds of the invention are preferably ... | 04/07/1987 |
| 4628103 | Process for the preparation of 3-amino-1,2,4-triazole A process for preparing 3-amino-1,2,4-triazole by reacting hydrazine hydrate, cyanamide and formic acid to form aminoguanidine formate and cyclizing the formate, wherein hydrazine hydrate and formic acid are simultaneously added to the cyanamide at 0° to... | 12/09/1986 |
| 4621046 | Pyrazolo(1,5-B)-1,2,4-triazole derivatives A novel pyrazolo[1,5-b]-1,2,4-triazole derivative represented by the general formula (I) is described. ##STR1## wherein R1 and R2 which may be the same or different, each represents a hydrogen atom or a substituent; X represents... | 11/04/1986 |
| 4563455 | Antiulcer fused imidazole compounds New fused imidazole compounds of the formula: ##STR1## wherein A is lower alkylene, R1 is hydrogen, lower alkyl, lower alkoxy or halogen, R2 is hydrogen, lower alkyl, cyclo(lower)alkyl, pyridyl, ar(lower)alkyl which may be substitute... | 01/07/1986 |
