Bizarre Patents
A simulation environment for the sport of boxing utilizing a robotic machine interface system which carries a person
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7361654 | Substituted heteroaryl amide modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof The present invention relates to new class of non-steroidal compounds which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including obesity, diabetes, inflammatory- and immune-associated disea... | 04/22/2008 |
| 7361672 | Heteroarylacetamide inhibitors of factor Xa The invention is concerned with novel heteroarylacetamides of formula (I) Rd—C(O)—N(Re)—Rc—CH2—C(O)—N(Ra)(Rb) (I) wherein Ra to Re are as def... | 04/22/2008 |
| 7348333 | Cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists There are described cycloalkyl derivatives of the formula (I) R1—Y-A-B-D-E-F-G (I) in which R1, Y, A, B, D, E, F and G have the meaning indicated herein, their preparation and their use as medicaments. The compounds a... | 03/25/2008 |
| 7238720 | Pharmaceutical use of N-carbamoylazole derivatives The present invention relates to use of 1-carbamoylazole derivatives as medicaments and pharmaceutical compositions containing 1-carbamoylazole derivatives as the active ingredient, based on their DPPIV inhibiting effects. The present invention provides a dipeptidyl... | 07/03/2007 |
| 6620933 | Azomethine yellow dye compound A azomethine yellow dye compound of general formula (I): General formula (I) ##STR1## wherein R1 and R2 each independently represent a hydrogen atom or a substituent; R3 represents a substituent; m indicates an integer fro... | 09/16/2003 |
| 6586552 | Aminoazole-blocked isocyanate components Aminoazole-blocked isocyanate components can be used as self crosslinking binders in heat-curable compositions.... | 07/01/2003 |
| 6465650 | Substituted N-ethylglycine derivatives for preparing PNA and PNA/DNA hybrids The invention provides a processes for the preparation of a compound of Formula I, or a salt thereof ##STR1## wherein PG is a urethane- or trityl-type protective group; X is NH, O, or S; Y is CH2, O, or NH; and B' is a base customary in nucleot... | 10/15/2002 |
| 6352985 | Benzimidazole compounds A benzimidazole compound represented by the formula (I): ##STR1## wherein R3 is a carboxyl group, a esterified carboxyl group, an amidated carboxyl group, an amino group, an amido group, or a sulfonyl group, or their pharmaceutically acceptable... | 03/05/2002 |
| 6190923 | Diethylenetriamine-N,N',N"-triacetic acid derivatives The present invention relates to the field of immunoassays for metal ions. The invention presents: chelators, chelates, antibodies specific for the chelates, tracers comprising chelates conjugated to detectable labels, and immunoassays utilizing the foreg... | 02/20/2001 |
| 6080770 | Modulators of molecules with phosphotyrosine recognition units The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their... | 06/27/2000 |
| 6075143 | Substituted N-ethylglycine derivatives for preparing PNA and PNA/DNA hybrids There are described N-ethylglycine derivatives of the formula I ##STR1## in which PG is a urethane-type or trityl-type amino protective group which is labile to weak acids, X is NH, O or S, Y is CH2, NH or O, and B' are bases customary in ... | 06/13/2000 |
| 5935973 | Heterocyclcarboxamide derivatives and their use as therapeutic agents Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof in which A is methylene or O; B is methylene or O; g is 0,1,2,3 or 4; R1 is an optional substituent; U is an alkylene chain optionally substituted by one or more... | 08/10/1999 |
| 5843937 | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomer... | 12/01/1998 |
| 5807875 | Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them Amino acid derivatives, suitable for the treatment of obesity. The following compound is exemplary of the class: (R,S)-N2 -(diphenylacetyl)-N-(4-hydroxyphenyl)methyl!-N5 -(1H-imidazol-2-yl)-ornithinamide.... | 09/15/1998 |
| 5705514 | Signal transduction inhibitor compounds A method of inhibiting the invasion and metastasis of malignant solid tumors in mammals, said method comprising administering to said mammal an anti-proliferative, anti-invasive and anti-metastasis effective amount of a compound selected from the group of... | 01/06/1998 |
| 5674886 | Triazolylated teritiary amine compound or salt thereof A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomergaly, etc., wherein A r... | 10/07/1997 |
| 5618793 | Nikkomycin analogs Compounds of the formula ##STR1## wherein R3, R4, J, K, Z, and Het are as set forth herein are described. The compounds of formula I are useful as agents in the treatment of fungal infections.... | 04/08/1997 |
| 5571925 | Angiotensin II antagonists This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.... | 11/05/1996 |
| 5538991 | Endothelin antagonists bearing 5-membered heterocyclic amides Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral... | 07/23/1996 |
| 5510379 | Sulfonate ACAT inhibitors ଲ-Carboxy sulfonates of the formula ##STR1## wherein R1 is aryl, R3 and R4 are hydrogen or alkyl, Y is -O-, -S-, or -NR2 -, and R5 is alkyl or aryl are potent inhibitors of the enzyme acyl ... | 04/23/1996 |
| 5506263 | Benzyl derivatives and pesticides containing them Benzyl derivatives of the formula I ##STR1## where A is CH2, CHCl, CH-alkyl, CH-alkoxy, CH-alkylthio or N-alkoxy, B is OH, alkylthio, alkoxy or alkylamino, U, V, W are hydrogen, halogen, alkyl or alkoxy, D is ##STR2## where R' is hydrogen ... | 04/09/1996 |
| 5502068 | Cyclopropylpyrroloindole-oligopeptide anticancer agents The invention is directed to novel cyclopropylpyrroloindole-oligopeptide compounds which are useful as anticancer agents. The novel cyclopropylpyrroloindole-oligopeptide compounds have the following general structure: ##STR1## wherein, Het1... | 03/26/1996 |
| 5482954 | Signal transduction inhibitor triazole and diazole compounds A discovery underlying this invention is the concordance between particular cellular signaling mechanisms and cancer cell growth and metastasis. It has now been discovered that certain compounds inhibit the signal transduction required for the maintenance... | 01/09/1996 |
| 5416110 | Benzyl derivatives and pesticides containing them Benzyl derivatives of the formula I ##STR1## where A is CH2, CHCl, CH-alkyl, CH-alkoxy, CH-alkylthio or N-alkoxy, B is OH, alkylthio, alkoxy or alkylamino, U, V, W are hydrogen, halogen, alkyl or alkoxy, D is ##STR2## where R' is hydrogen ... | 05/16/1995 |
| 5395849 | Hybrid antitumor compounds containing a cyclic enediyne and a DNA-binder The present invention provides novel antitumor agents which are hybrid molecules consisting of a cyclic enediyne unit attached to a DNA-binding unit via a linker unit, and having the general formula (I) D--(OCH2)m --O--(CH2) | 03/07/1995 |
| 5376670 | 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical c... | 12/27/1994 |
| 5359078 | Signal transduction inhibitor compounds A compound having the formula: Y--(CH2)p --Ar11 --X--Ar12 wherein: p is an integer of from 0 to 4; Ar11 and Ar12 are each aromatic moieties independently selected from the group consisting of phenyl,... | 10/25/1994 |
| 5234917 | Substituted 5-(alkyl)carboxamide imidazoles Angiotensin II receptor antagonists having the formula: ##STR1## which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma pharmaceutical compositions including these antagonists, and me... | 08/10/1993 |
| 5217985 | Renal-selective biphenylalkyl 1H-substituted-1,2,4-triazole angiotensin II antagonists for treatment of hypertension Renal-selective compounds are described which, in one embodiment, are prodrugs preferentially converted in the kidney to compounds capable of blocking angiotensin II (AII) receptors. These prodrugs are conjugates formed from two components, namely, a firs... | 06/08/1993 |
| 5110986 | Synthesis of N-t-alkyl-1,2-diacylhydrazines This application relates to a process for preparing a N-t-alkyl-1,2-diacylhydrazine by reacting a 1,3,4-oxadiazole with a tertiary alkyl cation precursor in the presence of a strong acid catalyst. Preferably, the 1,3,4-oxadiazole is a 2,5-disubstituted-1,... | 05/05/1992 |
| 5055471 | Fungicides This invention relates to derivatives of propanoic acid of the formula ##STR1## Useful as fungicides, insecticides and miticides, to processes for preparing them, to compositions containing them, and to methods of using them to combat fungi, especial... | 10/08/1991 |
| 5051517 | Process for the preparation of herbicidally active 3-amino-5-aminocarbonyl-1,2,4-triazoles 3-amino-5-amino-carbonyl-1,2,4-triazoles of the formula ##STR1## are obtained in good yields and in high purity when a chloroformadine hydrochloride of the formula ##STR2## are reacted with an oxamohydrazide of the formula ##STR3## Thi... | 09/24/1991 |
| 4962119 | Triazole derivatives of fenamates as antiinflammatory agents The present invention is novel compounds which are 1,2,4-triazoles, derivatives of fenamates and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use thereof. The invention compounds are now found to... | 10/09/1990 |
| 4925864 | Phenyltriazole derivative and insecticide A phenyltriazole derivative of the formula: ##STR1## wherein X is a halogen atom, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, a nitro group, a phenoxy group, an amino group, a cyano group, a 1-pyrrolyl group or a halogen-subst... | 05/15/1990 |
| 4612309 | Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of ... | 09/16/1986 |
| 4607043 | Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acids and derivatives as cognition activators Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-alkanoic acids, base addition salts, esters, and amides are useful as agents for the reversal of amnesia. Pharmaceutical compositions containing said compounds and methods for using said compositions for treating... | 08/19/1986 |
| 4602944 | Herbicidal pyridinium compounds and compositions Herbicidally-active compounds of the formula: ##STR1## where: Y represents halo or trifluoromethyl; Z represents hydrogen, halo, trifluoromethyl or nitro; A represents --N.dbd. or ##STR2## where X is as defined above for Z; and R represents --N... | 07/29/1986 |
| 4568752 | Recording material for color photography Recording material for color photography, which contains, in at least one silver halide emulsion layer, at least one yellow coupler of the formula ##STR1## in which R1, R2, R3 and R4 are alkyl, cycloalkyl or ... | 02/04/1986 |
| 4416683 | Benzamides, compositions and agricultural method N-Aryl benzamides wherein the aryl group is a nitrogen containing heterocycle are useful as selective herbicidal agents. Compositions containing the novel benzamides and a herbicidal method of selective weed control are disclosed.... | 11/22/1983 |
| 4314069 | Herbicidal compound, herbicidal composition containing the same, and method of use thereof -[4-(4-Trifluoromethylphenoxy)phenoxy]alkanecarboxylic acids (the "4-trifluoromethylphenoxy group" of which may contain one chlorine atom as a substituent) and derivatives thereof useful as a herbicide, a herbicidal composition containing the compo... | 02/02/1982 |
