Class 548/256 - Polycyclo heterocyclic ring system containing ring oxygen

Subclass of Class 548 - Organic compounds -- part of the class 532-570 series
Definition: Compounds containing a polycyclo heterocyclic ring system
No. of patents: 83
Last issue date: 08/19/2008

«First «Previous1 2 3 Next»Last»

Number	Title	Issue Date
7414134	B1 bradykinin receptor antagonists The invention encompasses novel compounds and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for treatment of diseases mediated by B1 bradykinin receptor. ...	08/19/2008
RE39663	Electron-deficient nitrogen heterocycle-substituted fluorescein dyes The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitrogen heteroc...	05/29/2007
6962936	Triazole-derived kinase inhibitors and uses thereof Described herein are compounds that are useful as protein kinase inhibitors having the formula: where Ht, R2, T, and m are as described in the specification. The compounds are useful...	11/08/2005
6858607	7,8-fused 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted 4H-chromene and analogs thereof, represented by the general Formula I: or pharmaceutically acceptable salts or prodrugs thereof, wherein: wherein A, R1	02/22/2005
6664399	Triazole linked carbohydrates Disclosed is an invention concerning triazolyloligosaccharides, oligosaccharides wherein the bonding between the saccharide groups is via a triazole group and methods for their preparation....	12/16/2003
6469051	Diaminorhodamine derivative A compound represented by the following general formula: ##STR1## wherein R1 and R2 represent amino groups present at adjacent positions each other on the phenyl ring; R3, R4, R5 and R6 ind...	10/22/2002
6441197	Diaminofluorescein derivative A compound represented by the following formula (I): ##STR1## wherein R1 and R2 represent amino group that substitute at adjacent positions on the phenyl ring, provided that either of R1 and R2 represents a mono...	08/27/2002
6221604	Electron-deficient nitrogen heterocycle-substituted fluorescein dyes The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitro...	04/24/2001
6194438	Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one, and compositions and methods for inhibiting abnormal cell growth comprising said derivatives The present invention relates to compounds of the formula ##STR1## wherein R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of Formula I...	02/27/2001
6096897	Endothelin receptor antagonists Novel pyrroles, pyrazoles and triazoles, pharmaceutical compositions containing these compounds and their use as endothelin receptor antagonists are described....	08/01/2000
6008219	Bicyclic amine derivatives and their use as anti-psychotic agents This invention relates to compounds of formula (I) ##STR1## which are useful as modulators of D3 receptors, in particular as antipsychotic agents....	12/28/1999
5874590	Diaminofluorescein derivative A compound useful for the measurement of nitrogen monoxide under a substantially neutral condition which is represented by the following formula (I): ##STR1## wherein R1 and R2 represent amino groups that substitute at adja...	02/23/1999
5698575	Chromone compounds, pharmaceutical compositions containing the same, and use of the same A chromone derivative of the formula (I): ##STR1## wherein R11 is a pyrazolyl, pyrrolyl, triazolyl, benzotriazolyl, benzimidazolyl, indazolyl, or indolyl group, R2, R3, R4, and R5 is independentl...	12/16/1997
5696154	Brefeldin A derivatives and their utility in the treatment of cancer Provided are brefeldin A derivatives of the formula: ##STR1## wherein one of R1 and R2 is H and the other of R1 and R2 is a substituent group having 1 to 12 carbon atoms containing a basic nitrogen atom or ...	12/09/1997
5674894	Amidine derivatives useful as platelet aggregation inhibitors and vasodilators The current invention discloses novel amidine derivatives with nitric oxide donating property that can inhibit platelet aggregation and promote vasodilation in a single compound....	10/07/1997
5612370	Phenylglycine and phenylalaninen amido benzopyran derivatives Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein a, b and d are all carbon atoms or one of a, b and d is a nitrogen atom or --N(O)-- and the others are carbon atoms; Y is a single bond, --CH2 --, ...	03/18/1997
5571925	Angiotensin II antagonists This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals....	11/05/1996
5565482	Heteroarylpyranopyrazolyl derivatives for the treatment of inflammation A class of benzopyranopyrazolyl derivatives is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I ##STR1## wherein A is --(CH2)m --X--(CH...	10/15/1996
5538991	Endothelin antagonists bearing 5-membered heterocyclic amides Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral...	07/23/1996
5510362	Imidazole, triazole and tetrazole derivatives A class of substituted imidazole, triazole and tetrazole derivatives of formula (I), wherein the broken circle represents two non-adjacent double bonds in any position in the five-membered ring; two, three or four of V,W,X,Y and Z represent nitrogen and t...	04/23/1996
5498616	Cysteine protease and serine protease inhibitors The present invention is directed to irreversible inhibitors of serine and cysteine proteases which most preferably contain a 1-oxytriazole or 1-oxyimidazole functionality. Methods for the use of the protease inhibitors are also described....	03/12/1996
5488064	Benzo 1,3 dioxole derivatives Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof where A is phenyl, naphthyl or dihydro- or tetrahydronaphthyl optionally substituted on the aromatic ring by one to three substituents independently selected from halogen...	01/30/1996
5324833	Protected amino acids and process for the preparation thereof Compounds of the formula I, ##STR1## in which 'R1 is an amino protective group, and n stands for 1 or 2, R1 denotes hydrogen or an amino protective group, R2 denotes hydrogen or a carboxyl protective group and R3...	06/28/1994
5312852	2-(2-hydroxy-3-perflu oroalkylthiomethyl-5-alkylphenyl)-2H-benzotriazoles, processes for preparing them and stabilized compositions thereof 2-(2-Hydroxy-3-perfluoroalkylthiomethyl-5-alkylphenyl)-2H-benzotriazoles are prepared by reacting the Mannich base hydrohalide or quaternary salt of a 2-(2-hydroxy-5-alkylphenyl)-2H-benzotriazole with a perfluoroalkyl mercaptan. The products exhibit outst...	05/17/1994
5223616	Heterocyclic disperse dye compound, their production and their use for dyeing or printing of hydrophobic fibers A heterocyclic compound which is useful for dyeing or printing hydrophobic fiber materials and which has the following formula (I), ##STR1## wherein A1, A2, A3 and A4 are each hydrogen, halogen, alkyl, alkoxy or...	06/29/1993
5164509	Benzodiazolo analogs Novel potassium channel activators of the formula ##STR1## where Y, X, X1, X2 (N or O), and R1 -R4 are as defined herein, are disclosed....	11/17/1992
5102707	Diorganopolysiloxanes containing benzotriazole functional groups Linear and cyclic diorganopolysiloxanes containing benzotriazole functional groups are well suited for the coating of optical fibers and for lubricating plastics, e.g., PVC....	04/07/1992
5053071	Chromane herbicides This invention pertains to novel heterocyclic 2,3-dihydrobenzofuran and chromane compounds, including stereoisomers, agriculturally suitable compositions containing them, and their use as broad spectrum herbicides....	10/01/1991
5034531	Fused polycyclic pyranyl compounds as antiviral agents Novel polycyclic pyranyl compounds, pharmaceutical compositions, and their use as anti-viral agents are disclosed....	07/23/1991
5001115	Prodrugs of biologically active hydroxyaromatic compounds Prodrugs of bio-active hydroxyaromatic drugs having the structural formula: A pharmaceutically acceptable prodrug of a biologically active, therapeutically effective hydroxyaromatic drug, said prodrug being selected from the group consisting of, (A) compounds ...	03/19/1991
4996316	Process for the preparation of tertiary N, N-dimethylamines A process for the preparation of tertiary N,N-dimethylamines by the reaction of primary amines, formaldehyde, and hydrogen under pressure and at elevated temperature in the presence of a nickel-containing hydrogenation catalyst in the liquid phase. The hy...	02/26/1991
4914206	Lankacidin derivatives and production thereof The present invention provides lankacidin derivatives of the formula ##STR1## and procedures for the production thereof. The lankacidin derivatives [1] show excellent antimicrobial activities and thus can be used for prophylaxis and treatment of infe...	04/03/1990
4881967	Heterocyclic 2,3-dihydrobenzofuran herbicides This invention pertains to novel heterocyclic 2,3-dihydrobenzofuran and chromane compounds, including stereoisomers, agriculturally suitable composition containing them, and their use as broad spectrum herbicides....	11/21/1989
4782169	4,7-dioxatricyclo(3.2.1.0³,6)octane ether Compounds of the Formula I, II, III, VI and VII ##STR1## wherein the symbols have defined meanings are herbicides, plant growth regulators or intermediates thereof....	11/01/1988
4743595	Process for preparing 2-amino-5-nitrophenol derivatives A process for efficiently preparing 2-amino-5-nitrophenol derivatives in which benzoxazole derivatives are subjected to nucleophilic substitution reaction at the 5 position thereof to obtain corresponding benzoxazole derivatives, and the oxazole ring of t...	05/10/1988
4713393	Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents Phenylalkyl-2,3-dihydrobenzofurans and analogs were prepared by (1) nucleophilic substitution involving an appropriately substituted 2,3-dihydrobenzofuranol (or 2,3-dihydrobenzopyranol) and a cinnamylhalide followed by reduction; or (2) by Wittig reaction...	12/15/1987
4692526	Process for preparing benzopyrano (2,3-d) triazoles A process for preparing a compound of formula (I) ##STR1## wherein X phenyl optionally substituted by one halogen, C1-4 alkyl or C1-4 alkoxy; or pyridyl; R1 is hydrogen or C1-6 alkyl; and n is an integer of...	09/08/1987
4670041	Oxabicycloalkane herbicides Compounds of the formula ##STR1## wherein X is (--CR4 R4 --)m in which m is 0 or 1; Y is (--CR5 R6 --)n in which n is 0, 1 or 2; Z is (--CR7 R7 --)p in which p i...	06/02/1987
4659730	Aromatase inhibiting imidazole derivatives This invention provides certain azole derivatives and their pharmaceutical formulations. Also provided is a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering the azole derivatives....	04/21/1987
4588821	2-oxabicyclo[2.2.1]heptan-6-ol ether herbicides Compound of the formula ##STR1## wherein X is --C(O)Hal, --CN, or --C(O)Y in which Y is OR1 or NR1 R2 in which R1 and R2 are H or hydrocarbyl or the like and R are certain optionally substituted ...	05/13/1986

«First «Previous1 2 3 Next»Last»

PatentStorm

Bizarre Patents

PatentStorm News

Class 548/256 - Polycyclo heterocyclic ring system containing ring oxygen