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Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 8143418 | Dimeric small molecule potentiators of apoptosis Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an ef... | 03/27/2012 |
| 7884211 | Dimeric small molecule potentiators of apoptosis Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an ef... | 02/08/2011 |
| 7834190 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof An objective of the present application is to provide an industrially practicable method for producing an optically-active 3-amino-2-hydroxypropionic cyclopropylamide derivative or salt thereof from an inexpensive easily-available starting material. The derivative o... | 11/16/2010 |
| 7816538 | Dimeric small molecule potentiators of apoptosis Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an ef... | 10/19/2010 |
| 7767825 | 2,2′,6,6′-tetraoxazolinyl biphenyl ligand and method for preparing the same The present invention relates to a method for preparing 2,2′,6,6′-tetraoxazolinyl biphenyl ligand in chemical industry field. In the present invention, compound (III) is reacted with an activator that can activate the hydroxyl group selected from the group consi... | 08/03/2010 |
| 7754891 | 5,5′-Position linked 1,1′-biphenyl axial chiral ligand and method for preparing the same The present invention relates to a 5,5′-position linked 1,1′-biphenyl axis chiral ligand in chemical industry field. The present invention incorporates both the central chirality of oxazoline and the axial chirality of diphenyls. Such ligand can be used in vario... | 07/13/2010 |
| 7358378 | Processes for the preparation of paclitaxel The present invention provides processes for the production of paclitaxel. Paclitaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then der... | 04/15/2008 |
| 7358368 | Azlactone compound and method for preparation thereof Compounds represented by formula (II): wherein M is a hydrogen atom, sodium, potassium, or lithium; P is a hydrogen atom, an alkyl group, and the like; and the wavy line indicates a cis form, a trans form, or a mixture ther... | 04/15/2008 |
| 7348436 | Compounds useful for the synthesis of (+)-discodermolide and methods thereof Compounds and methods useful for the synthesis of (+)-discodermolide, a naturally occurring microtubule stabilizing agent useful as an anti-cancer agent. ... | 03/25/2008 |
| 7309792 | Dimeric small molecule potentiators of apoptosis Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an ef... | 12/18/2007 |
| 7279586 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative. ... | 10/09/2007 |
| 7241900 | Synthesis of indole thiazole compounds as ligands for the Ah receptor A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of for... | 07/10/2007 |
| 7205320 | Phosphodiesterase 4 inhibitors PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 ... | 04/17/2007 |
| 7166604 | Antiviral agents This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals as well as novel intermedia... | 01/23/2007 |
| 7164026 | Polymer-carrying optically active binaphthyl type oxazoline compound A polymer-carrying optically active binaphthyl type oxazoline compound having axial asymmetry, represented by the following general formula (1) (wherein R1 and R2 may be the same or differen... | 01/16/2007 |
| 7126005 | Process for preparing florfenicol The present invention is directed to a new process of preparing highly pure Florfenicol. The invention is further directed to new oxazolidine derivatives useful in making Florfenicol and processes of making these derivatives. Examples of such intermediates include (... | 10/24/2006 |
| 7115758 | Vitamin D derivatives with cyclic substructures in the side chains, process and intermediate products for their production, and the use for the production of pharmaceutical agents The invention relates to vitamin D derivatives of general formula I, process for their production, intermediate products of the process as well as the use for the production of pharmaceutical agents. ... | 10/03/2006 |
| 7081536 | Isoxazoline derivatives as P N ligands The invention relates to novel ligands of the phosphanylbenzothiophenyl-dihydroisoxazoline, phosphanyl-dihydrooxazolyl-indole and phosphanyl-dihydrooxazolyl-benzofuran type, especially compounds of formula I and ... | 07/25/2006 |
| 7078403 | Antiviral agents Disclosed herein are compounds of formula II: wherein Alk, Z, X1, X2, R1, —R10 and R11 are defined herein, and their salts and pharmaceutically acceptable deriva... | 07/18/2006 |
| 7045634 | Prostamide receptor antagonists The present invention provides prostamide receptor antagonist compounds that may be represented by the general formula I. wherein A, R1, R2, R3, R4 and R6 ar... | 05/16/2006 |
| 7041831 | Diastereoselective synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors Disclosed is a method of preparing a composition comprising a compound represented Structural Formula (I): The method comprises the step of reacting an aldehyde compound R10CHO with an isonitrile compound rep... | 05/09/2006 |
| 7030202 | Graft copolymers and method to prepare same A thermally processable graft copolymer formed from a water soluble polymer and a water insoluble polymer, wherein the graft copolymer forms a hydrogel upon exposure to water. A method to form such a hydrogel-forming graft copolymer by copolymerizing a water soluble... | 04/18/2006 |
| 6960474 | Method for the treatment of a condition remediable by administration of a selective androgen receptor modulator Selective androgen receptor modulators (SARMs) having antagonist activity in hormone-dependent tumors while exhibiting no activity or agonist activity against other nontumor tissues containing the androgen receptor as well as methods for identifying, designing and u... | 11/01/2005 |
| 6875882 | Synthesis of benzonitriles from substituted benzoic acid There is a significant demand for organic nitriles, based on their versatility in reactions. Compounds prepared from nitriles have properties including superoxide inhibition, ferrielectric liquid crystal dopant, antipicornaviral agents, anti-inflammatory agents, ant... | 04/05/2005 |
| 6864270 | Iron binding agents Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a therapeutically-effective amount of a compound of formula (I) or (IV), i.e. sufficien... | 03/08/2005 |
| 6762199 | Indane derivatives The invention is directed to physiologically active compounds of general formula (I): wherein: R1 represents aryl, heteroaryl or a group R3—L2—Ar1—L3—... | 07/13/2004 |
| 6753431 | Production of mixed acid anhydride and amide compound There is disclosed an advantageous mixed acid anhydride production method of formula (1): R1C(O)OY(O)n(R2)p (1) wherein R1, R2 and Y denote the same as defined bel... | 06/22/2004 |
| 6706664 | Benzoxazole compounds, process for the preparation thereof and herbicides The present invention relates to a benzoxazole compound represented by the following formula (1): wherein R1 to R4 each represents hydrogen atom, C1-6 alkyl group, C1-4 alkoxy ... | 03/16/2004 |
| 6649609 | Benzimidazole derivatives and pharmaceutical compositions comprising these compounds The present invention relates to novel 1-phenylbenzimidazole derivatives having particular alkoxycarbonyl substituents in the 5-position of the benz ring and having particular cyclic substituents in the meta-position of the phenyl ring, as well as to phar... | 11/18/2003 |
| 6649643 | Imidazol-4-ylmehanols and their use as inhibitors of steroid C17-20 lyase Imidazol-4-ylmethanols and their uses for preventing and treating primary tumors, metastasis and recurrence of tumors, various symptoms accompanying tumors, prostatic hypertrophy, virilism, hirsutism, male pattern alopecia, precocious puberty, endometrios... | 11/18/2003 |
| 6645984 | Arylisoxazoline derivatives, processes for their preparation and their use as pesticides Compounds of the formula (I), ##STR1## are described in which X is halogen, cyano, nitro, (C1 -C4)-alkyl, (C1 -C4)-alkoxy, (C1 -C4)-alkylthio or (C1 -C4)-alkylsulf... | 11/11/2003 |
| 6642218 | Vitamin D derivatives with carbo- or heterocyclic substituents at C-25, a process for their production, intermediate products and their use for producing medicaments The invention relates to vitamin D derivatives of formula (I), processes for the production thereof and uses thereof: ##STR1## wherein Y1, Y2, R1 -R6, Q and Z are as defined herein.... | 11/04/2003 |
| 6624324 | Process for producing optically active hemiesters There is disclosed a process for producing an optically active hemiester of formula (1): ##STR1## wherein R1, R2 and R5 represent the same meanings as described below, which comprises reacting a cyclic acid anhydride o... | 09/23/2003 |
| 6613920 | Vitamin D derivatives with carbo- or heterocyclic substituents at C-25, process for their production, intermediate products and use for the production of pharmaceutical agents The invention relates to vitamin D derivatives of formula (I), processes for the production thereof and uses thereof: ##STR1## wherein Y1, Y2, R1 --R6, Q and Z are as defined herein.... | 09/02/2003 |
| 6608066 | Tissue factor antagonists and methods of use thereof The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for treating or prophylaxis of undesi... | 08/19/2003 |
| 6600058 | Vitamin D derivatives with carbo- or heterocyclic substituents at C-25, a process for their production, intermediate products and their use for producing medicaments The invention concerns new vitamin D derivatives of general formula (I) a process for their production, their use for production of medicaments, and intermediate products used in the process. ##STR1##... | 07/29/2003 |
| 6583292 | Method for the esterification of alcohols and compounds useful therefor as potential anticancer agents Described herein is a method for preparing an ester by (a) admixing a compound having the formula I: ##STR1## with a base to form an intermediate, and (b) admixing the intermediate produced in step (a) with a compound composed of an alcohol, an alkoxide, ... | 06/24/2003 |
| 6576628 | 3-aryl-succinamido-hydroxamic acids, methods for producing said acids and medicaments containing the same The invention relates to inhibitors of matrix metalloproteases, more specifically a 3-aryl-succinamido-hydroxamic acid of formula (I) ##STR1## and its salt, ester and derivative thereof, along with methods of producing a compound of formula (I) and pharma... | 06/10/2003 |
| 6573286 | 2-(2,6-disubstituted phenyl)-4-aryl-5-alkyl-1,3-oxazoline compounds Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling aphids, insects and mites.... | 06/03/2003 |
| 6476232 | 4-(2-amino-1-hydroxyethyl)oxazoline derivative and method for producing same A 4-(2-amino-1-hydroxyethyl)oxazoline derivative of the formula [XIII] ##STR1## and a method for producing the same, in which R4 is an optionally substituted alkyl, an optionally substituted aryl, an optionally substituted heteroaryl, an option... | 11/05/2002 |
