Quotables
"The man with a new idea is a crank until the idea succeeds."
Samuel Clemens
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7960558 | Pharmaceutical intermediate for synthesizing ACE inhibitors and the use thereof The compounds of the general Formula (I), wherein R1 is aryl or alkyl; R2 represents alkyl; R3 represents alkyl or aralkyl, are valuable pharmaceutical intermediates, which can be prepared by reacting a compound of the general Formul... | 06/14/2011 |
| 7375124 | Use of α-phenylthiocarboxylic and α-phenyloxycarboxylic acids with serum-glucose-lowering and serum-lipid-lowering activity The use is described of derivatives of α-phenylthiocarboxylic and α-phenyloxycarboxylic acids with formula (i): in which the substituents have the meanings described in the text, for the preparation of a medicine for the prophylaxis and treatment of diabetes, part... | 05/20/2008 |
| 7226940 | Substituted heterocycles for the treatment of diabetes and other diseases The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymph... | 06/05/2007 |
| 7202366 | Heterocyclic analogs of diphenylethylene compounds Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II di... | 04/10/2007 |
| 7115747 | Process for preparing oxazole intermediates Disclosed are compounds of formula III and a process to prepare a compound of formula III wherein R1, R2, R3 and R6 are defined herein, using a zinc chloride/optionally... | 10/03/2006 |
| 7105531 | Tricyclic protein kinase inhibitors This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyrosine kinase and are antiproliferative agents. ... | 09/12/2006 |
| 7087576 | Dipeptide phenyl ethers Novel dipeptide ethers are effective for lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels. The dipeptide ethers are also useful for the treatment and/or prophylaxis of diabetes, obesity, inflammation and autoimmune disease... | 08/08/2006 |
| 7078424 | N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating... | 07/18/2006 |
| 7071218 | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases The present invention relates to certain compounds of Formula (I) which can be useful in the treatment of diseases, such as, cancer, metabolic disorders, Type 2 Diabetes, dyslipidemia and/or hyperchloesterolemia: ... | 07/04/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 7009048 | Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye A dye-forming coupler of the formula (I). A silver halide photographic light-sensitive material that contains at least one dye-forming coupler of the formula (I). A method for producing an azomethine dye, which method comprises using a compound of the formula (I): | 03/07/2006 |
| 6969749 | Azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 11/29/2005 |
| 6953859 | Production process for 5-alkyl-oxazolidin-2,4-dione The object of the present invention is to produce a 5-alkyl-oxazolidin-2,4-dione by an industrially advantageous method. The invention relates to novel process for producing a high-purity 5-alkyl-oxazolidin-2,4-dione comprising the steps of reacting a 2-hydroxycarbo... | 10/11/2005 |
| 6924301 | Composition for treating or preventing arrhythmia A composition for treating or preventing arrhythmia containing as an active ingredient a cPLA2 inhibitor, for example a compound represented by formula (I): wherein R1 is optionally substituted ar... | 08/02/2005 |
| 6894133 | Azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 05/17/2005 |
| 6699896 | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds having the structure ##STR1## wherein A is OR5, or ##STR2## R1 is alkyl, cycloalkyl of 3-8 carbon atoms, thienyl, furyl, pyridyl, ##STR3## R2 is H, alkyl, or aryl; R3 | 03/02/2004 |
| 6670447 | Amino acid N-carboxyanhydrides with acyl substituents on nitrogen atoms thereof This invention provides amino acid N-carboxyanhydrides, each of which has an N-acyl substituent on its nitrogen atom, is represented by the following formula (1): ##STR1## readily reacts with nucleophilic reagents such as free amino acids, alcohols, ... | 12/30/2003 |
| 6593323 | Benzimidazole compounds and drugs containing the same A benzimidazole compound or a salt thereof which has an inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula ... | 07/15/2003 |
| 6569873 | Azolidines as beta-3 adrenergic receptor agonists This invention provides compounds of Formula I having the structure ##STR1## wherein, A, X, Y, Z, W, R1, R2, R3, R4, R5, and R6 are as defined hereinbefore or a pharmaceutically acceptable salt ... | 05/27/2003 |
| 6552054 | Chromone derivatives, process for the preparation of the same and uses thereof The invention provides chromone derivatives of the following general formula, a process for preparing such chromone derivatives and a prophylactic and therapeutic agent comprising such chromone derivatives for bone diseases and chondropathy: ##STR1##... | 04/22/2003 |
| 6552058 | Oxazolidinedione derivatives and their use Novel 2,4-oxazolidinedione compounds of the formula: ##STR1## wherein R is a hydrocarbon residue or a heterocyclic group each of which may be substituted; Y is --CO--, --CH(OH)-- or --NR3 -- (wherein R3 is an alkyl group which may be... | 04/22/2003 |
| 6538140 | Complex oxonol infrared radiation sensitive compounds Infrared radiation-sensitive compounds have been found that are represented by Structure DYE as follows: ##STR1## wherein R is a substituted or unsubstituted alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted heterocy... | 03/25/2003 |
| 6506905 | Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid 3-(alk-2-ynyloxy)carbonyl-5-oxazolidine carboxylic acid and its analogs having a formula ##STR1## and wherein R1 is hydrogen, aryl, heteroaryl, alkyl, alkenyl, alkynyl, R2 and R3 are independently selected from hydrogen, a... | 01/14/2003 |
| 6482953 | 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them Disclosed is a 2-benzyloxy-4-nitro-5-substituted-acylanilide compound of the general formula I: ##STR1## wherein R is hydrogen or an alkyl group, each RA is an independently selected substituent and n is 0-5, and Y is a substituent group linked to t... | 11/19/2002 |
| 6479514 | Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria. ##STR1##... | 11/12/2002 |
| 6465501 | Azolidines as 댣 adrenergic receptor agonists This invention provides compounds of Formula I having the structure ##STR1## wherein, A, X, Y, Z, W, R1, R2, R3, R4, R5, and R6 are as defined hereinbefore or a pharmaceutically acceptable salt ... | 10/15/2002 |
| 6448286 | Imino pyrrolidine derivatives useful as nitric oxide synthase inhibitors The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.... | 09/10/2002 |
| 6399640 | Arylthiazolidinedione and aryloxazolidinedione derivatives Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diab... | 06/04/2002 |
| 6384231 | Method of producing 2,4-oxazolidinediones and metal salts thereof A method of producing a metal salt of 2,4-oxazolidinedione of the general formula (III) wherein a 2hydroxycarboxylate fo the general formula (I), urea and a metal alkoxide of the formula (II) are reacted in an aromatic hydrocarbon; or a 2-hydroxycarboxyla... | 05/07/2002 |
| 6359142 | Sulfonyl oxazolones and their use for combating undesirable microorganisms Novel sulphonyloxazolones of the formula ##STR1## in which R1 represents alkyl or represents optionally substituted heterocyclyl or represents a radical of the formula ##STR2## in which R3 represents halogen, alkyl or phenyl, R... | 03/19/2002 |
| 6331633 | Heterocyclic analogs of diphenylethylene compounds Novel diphenylethylene compounds containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. In co... | 12/18/2001 |
| 6288096 | Thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives Novel thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives, process for their manufacture, pharmaceutical preparations containing them and the use of the compounds in conditions associated with insulin resistance.... | 09/11/2001 |
| 6288063 | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula (T)x A--B--D--E--G whe... | 09/11/2001 |
| 6277997 | Process for the preparation of chiral lactones The present invention relates to a process for the preparation of compounds of formula I ##STR1## wherein R1 and R2 are as defined in the specification as well as to the novel intermediates obtained by said process.... | 08/21/2001 |
| 6251829 | Herbicidal benzoyloxy carboxylates and carboxamides This invention relates to herbicidal alpha-(2,4,5-trisubstituted)- and alpha-(2,5-disubstituted)-benzoyloxy-alpha-beta-, and/or beta-gamma-unsaturated-carboxylates and their derivatives, to compositions which contain these compounds, and to methods of use... | 06/26/2001 |
| 6204390 | Synthesizing method for a 3-substituted-3-oxo-2-(2,4-oxazolidinedione-3-yl) propionic acid amide compound A synthesizing method for a 3-substituted-3-oxo-2-(2,4 -oxazolidinedione-3-yl)propionic acid amide compound represented by the following Formula [I], by reacting a compound represented by the following Formula [II] with a compound represented by the follo... | 03/20/2001 |
| 6194575 | Method for producing 1,3-di-substituted 2-nitroguanidines The present invention relates to a process for the preparation of compounds of the formula (I) ##STR1## by reacting compounds of the formula (II) ##STR2## in which Het, R1, R2 and R4 are as defined in the description, with... | 02/27/2001 |
| 6159673 | Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound An oxonol compound is represented by the following formula (I): ##STR1## in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M i... | 12/12/2000 |
| 6107251 | Oxazole derivative, process for producing the same, and herbicide The present invention is directed to oxazole derivatives represented by the formula [I]; ##STR1## wherein A represents a nitrogen atom or a R3 -substituted carbon atom; B represents a nitrogen atom, or an unsubstituted or X-substituted car... | 08/22/2000 |
| 6090946 | Process for the preparation of 3-(substituted phenyl)-5-alkylidene-1,3-oxazolidine-2,4-dione derivatives The present invention provides an industrial process for efficiently preparing a 3-(substituted phenyl)-5-isopropylidene-1,3-oxazolidine-2,4-dione derivative having a potent herbicidal activity without using phosgene or the like. The present inventio... | 07/18/2000 |
