Famous Patents
Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7053218 | Process for regioselective demethylation of -methoxy group in phenolic ester and diaryl ketone moieties Demethylation of 3′, 4′-dimethoxy or 3′, 4′, 5′-trimethoxy benzoic ester of a phenol is carried out in the presence of an excess of aluminum halide in an organic solvent to get 4′-Hydroxy, 3′-methoxy or 4′ hydroxy, 3′, 5′-dimethoxy benzoic acid e... | 05/30/2006 |
| 6638943 | Yohimbine dimers exhibiting binding selectivities for 댒 adrenergic receptors The present invention relates to yohimbine dimer compounds, pharmaceutical compositions containing such dimer compounds, methods of making such dimer compounds, and uses thereof. The yohimbine dimer compounds include compounds of formula (I): ##STR1#... | 10/28/2003 |
| 6500837 | Fused ring system containing indole as M4 selective aza-anthracene muscarinic receptor antagonists Disclosed are compounds of the Formula I ##STR1## and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, wherein R1 is hydrogen, lower alkyl, COOR7, (un)substituted aryl, (un)substituted heteroaryl, (un)substitu... | 12/31/2002 |
| 6376617 | Bioactive derivatives of camptothecin Water soluble polymeric conjugates of camptothecin consist essentially of N-(2-hydroxypropyl)methacryloylamide units linked via a spacer group to a residue of a camptothecin such as irinotecan or its non-soluble metabolite, 7-ethyl-10-hydroxy-camptothecin... | 04/23/2002 |
| 6359122 | Pyrocarbonic acid diesters and the preparation and use thereof The invention relates to the preparation of pyrocarbonic acid diesters by an improved process and to the novel pyrocarbonic acid diesters prepared according to said process as well as to the use thereof. The core of the invention is a process for the preparati... | 03/19/2002 |
| 5760029 | Spirocycle integrin inhibitors This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the v ଲ | 06/02/1998 |
| 5629317 | Tetrahydro-beta-carbolines The present invention provides novel tetrahydro-beta-carboline compounds having useful central nervous system activity. Further, there is provided tetrahydro-beta-carboline related compounds which are useful intermediates and have beneficial central nervo... | 05/13/1997 |
| 5441956 | Hydroisoquinoline derivatives | 08/15/1995 |
| 4335057 | 4-(2',2,2'-Trihalogenoethyl)-cyclobutane-1-sulfonic acid salts with optically active bases There is described a new process for the preparation of optically active 2-(2',2'-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3 position, and derivatives thereof. A racemate of certain cyclobutanones is reacted with a sulfurous aci... | 06/15/1982 |
| 4299967 | Process for producing optically active 2-(2,2-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3-position, and derivatives thereof, as well as novel 4-(2,2,2-trihalogenoethyl)-cyclobutane-1-sulfonic acid salts There is described a new process for the preparation of optically active 2-(2',2'-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3 position, and derivatives thereof. A racemate of certain cyclobutanones is reacted with a sulfurous aci... | 11/10/1981 |
| 4054571 | Nitrogen-containing polycyclic compounds and a process for the preparation thereof The invention relates to new eburnamenine derivatives of the general formula (I), ##STR1## wherein R1 stands for an alkyl group, R2 stands for a carboxy group, a functional carboxy derivative (preferably an ester group) or a gro... | 10/18/1977 |
| 3940387 | Yohimbine derivatives, process for their preparation and their applications The present invention relates to yohimbine derivatives. Said derivatives have the general formula ##SPC1## In which R is a radical ##EQU1## or R1 being an alkyl, aralkyl, alkylaryl, aryl group optionally carrying a nitro group, R... | 02/24/1976 |
