Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 7820827 | Substituted piperidine compounds and methods of their use Novel 3,4-disubstituted-4-aryl-piperidine compounds are disclosed. Pharmaceutical compositions containing the 3,4-disubstituted-4-aryl-piperidine compounds and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, inter alia, a... | 10/26/2010 |
| 7732616 | Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof Disclosed are compounds of the Formulas I and V and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, W, X and Y are as defined in ... | 06/08/2010 |
| 7304161 | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding dom... | 12/04/2007 |
| 7300991 | Cationic conductor, its intermediate, and lithium secondary battery using the conductor The disclosure discloses a polymer represented by the general formula, wherein Rp is a residue of a polymer of a compound having a polymerizable unsaturated bond, Q is an organic residue of n+1 valence... | 11/27/2007 |
| 7279470 | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may... | 10/09/2007 |
| 7273867 | Phenyl derivatives Novel compounds of the formula I in which W, X, Y, T, R1 and R2 are as defined in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders | 09/25/2007 |
| 7122563 | Derivatives of 4-demethylpenclomedine, use thereof and preparation thereof Thiocarbonate and thiocarbamate derivatives of 4-demethylpenclomedine are provided along with pharmaceutical compositions containing them and use for treating cancer. A method for preparing the derivatives is also provided. ... | 10/17/2006 |
| 6992192 | Carboline derivatives as PDE5 inhibitors Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as therapeutic agents. ... | 01/31/2006 |
| 6949539 | Admantane derivatives The invention provides compounds of general formula (I) in which m, A, R1 and Ar have the meanings defined in the specification; a process for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compo... | 09/27/2005 |
| 6815556 | Compounds having fungicidal activity and processes to make and use same A compound according to formula one that is useful as a fungicide is provided. Additionally, processes to make and use same are provided. ... | 11/09/2004 |
| 6727265 | Phenoxyethyl-thiourea-pyridine compounds and their use for treatment of HIV-infections The invention provides compounds which inhibit reverse transcriptase (RT) and which inhibit replication of a retrovirus, such as human immunodeficiency virus-1 (HIV-1). The compound of the invention are phenoxyethyl-thiourea-pyridines. The invention additionally pro... | 04/27/2004 |
| 6713492 | N-acyloxylated cycloalkyl compounds, composition containing the same and methods of use therefor Drugs or reagents containing as the active ingredient N-acyloxylated cycloalkyl compounds represented by general formula (I): wherein A is optionally substituted C4 or C5 cycloalkyl which may have o... | 03/30/2004 |
| 6667327 | Pyridine amido derivatives Disclosed are pyridine amido derivatives of the formula ##STR1## wherein X, Y, and R1 to R6 are as defined herein. These compounds are selective MAO-B inhibitors and are useful in treating diseases such as, for example, Alzheimer's a... | 12/23/2003 |
| 6608204 | Aromatic heterocyclic derivatives as enzyme inhibitors The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease ... | 08/19/2003 |
| 6603044 | Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same The present invention provides a phthalamide derivative of the formula (I): ##STR1## wherein A1 is (substituted) C1 -C8 alkylene, (substituted) C3 -C8 alkenylene, (substituted) C3 -C8... | 08/05/2003 |
| 6452008 | Pyridone derivatives and process for preparing the same A process for preparing a pyridone derivative (4), which comprises reacting the compound (1) with a hypochlorite or a hypobromite or with lead tetraacetate to give the compound (2), and reacting the compound (2) with the compound (3). Said process is pref... | 09/17/2002 |
| 6342504 | Aromatic heterocyclic derivatives as enzyme inhibitors The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease ... | 01/29/2002 |
| 6339045 | N-(unsubstituted or substituted)-4-substituted-6-(unsubstituted or substituted)phenoxy-2-pyridinecarboxamides or thiocarboxamides, processes for producing the same, and herbicides N-(substituted or unsubstituted)-4-substituted-6-(substituted or unsubstituted) phenoxy-2-pyridine carboxamide or thiocarboxamide represented by the general formula (I) and a process for producing the compound. A herbicide containing as an effective ingre... | 01/15/2002 |
| 6329360 | Hetero-linked phenylglycinolamides The hetero-linked phenylglycinolamides are prepared by reaction of the corresponding hetero-linked phenylacetic acids with appropriate phenylglycinols. The hetero-linked phenylglycinolamides are suitable as active compounds in medicaments.... | 12/11/2001 |
| 6316459 | O-benzyloxime ethers and crop protection agents containing these compounds O-Benzyloxime ethers of the formula I ##STR1## where X is substituted or unsubstituted CH2, NOalkyl Y is O, S, NR5 R1, R2, R5 are H, alkyl Z1, Z2 are H, halogen, methyl, methoxy, cyano R | 11/13/2001 |
| 6133442 | Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagonists Compounds of formula I ##STR1## wherein R1 signifies phenyl, substituted phenyl or heterocyclyl; R2 signifies phenyl or substituted phenyl; R3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, su... | 10/17/2000 |
| 6130226 | Immunotherapeutic agents Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor , nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory con... | 10/10/2000 |
| 6054470 | Src family SH2 domain inhibitors This invention relates to compounds of formula (1): ##STR1## wherein Ring a, A, B, C, D, E, R and Q are defined herein. These compounds possess the ability to disrupt the interaction between regulatory proteins possessing one or more SH2 domains and ... | 04/25/2000 |
| 6017937 | Pyridine derivative, anti-ulcer drug, and antibacterial drug A pyridine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein W represents a group expressed by the following formula 2 or formula 3; ##STR2## wherein R1 represents an alkenyloxy group; n represen... | 01/25/2000 |
| 6017934 | Thrombin inhibitors A compound which inhibits human thrombin and where has the structure ##STR1##... | 01/25/2000 |
| 6015905 | Process for the preparation of 2-(6-substituted pyrid-2-yloxymethyl) phenylacetate A process for preparing 2-(6-substituted pyrid-2-yloxymethyl)phenyacetates especially useful as intermediates for producing agricultural fungicides. The invention provides a compound having the formula (I): wherein A and D are independently selected from ... | 01/18/2000 |
| 5972975 | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders. ##STR1##... | 10/26/1999 |
| 5959116 | Pyridine-2, 3-dicarboximides their preparation and their use for controlling undesired plant growth A pyridine-2,3-dicarboxylic acid diester of the formula Va ##STR1## where the radicals R2 and R4 have the meanings set out in the specification and where R8 is a C1 -C4 -alkyl, C3 -C | 09/28/1999 |
| 5942623 | Process for the preparation of 2-(pyrid-2-yloxymethyl)phenylacetates as pesticide intermediates The invention relates to a process for the preparation of 2-(pyrid-2-yloxymethyl)phenylacetates of formula (I) useful as intermediates for agricultural pesticides, which comprises reacting a 2-pyridine of formula (II), wherein L is a leaving group and A, ... | 08/24/1999 |
| 5919792 | Integrin antagonists This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are v댣 antagonists, ... | 07/06/1999 |
| 5883282 | 3-(3-aryloxyphenyl)-1-(substituted methyl-s-triazine-2,4,6-oxo or thiotrione herbicidal agents There is provided a 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undes... | 03/16/1999 |
| 5877297 | Boronic compound complexing reagents and highly stable complexes Boron compound completing reagents, intermediate reagents of those reagents and methods of synthesizing these reagents. These reagents, including those shown as General Formula CII may be used, after further reactions described herein, to complex with bor... | 03/02/1999 |
| 5872224 | Boronic compound complexing reagents and highly stable complexes Boron compound complexing reagents, boron compound complexes, and methods of synthesizing these reagents and complexes are disclosed. These reagents and complexes include those shown in General Formula CIV, and General Formula CVI. In one embodiment, the ... | 02/16/1999 |
| 5869623 | Boronic compound complexing reagents and complexes Boron compound complexing reagents, intermediate reagents of those reagents, and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula II may be used, after further reactions described herein, to co... | 02/09/1999 |
| 5859210 | Boronic compound complexing reagents and complexes Boron compound complexing reagents, boron compound complexes, and methods of synthesizing these reagents and complexes are disclosed. These reagents and complexes include those shown in General Formula IV and General Formula VI. In one embodiment, the rea... | 01/12/1999 |
| 5849361 | Methine dyes based on formylaminopyridones Methine dyes of the formula ##STR1## where K is a carbocyclic or heterocyclic radical, X is nitrogen or a radical of the formula C--Q1, and Q1, Q2 and Q3 are hydrogen, substituted or unsubstituted C1 ... | 12/15/1998 |
| 5847192 | Boronic compound complexing reagents and complexes Boron compound complexing reagents and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula I and General Formula II may be used, after further reactions described herein, to complex with boronic c... | 12/08/1998 |
| 5837878 | Boronic compound complexing reagents and highly stable complexes Boron compound complexing reagents, boron compound complexes, and methods of synthesizing these reagents and complexes are disclosed. These reagents and complexes include those shown in General Formula CIII, General Formula CIV, and General Formula CVI. I... | 11/17/1998 |
| 5821239 | Substituted-4-amino-3-pyridinols There are disclosed various substituted 4-amino-3-pyridinol compounds of the formula below, ##STR1## where R1, R2 and R3 are as defined in the specification, which are useful for alleviating various memory dysfunction... | 10/13/1998 |
| 5811370 | Azamethine dyes Azamethine dyes of the formula ##STR1## where W is oxygen, sulfur or a radical of the formula --NH--CO--, --NH--COO-- oder --NH--SO2 --, Z1 is C1 -C4 -alkyl with or without substitution, phenyl or C1 | 09/22/1998 |
