Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 7276539 | 3-Phenyl-2-arylalkylthiopropionic acid derivatives as selective agonists of ppar-alpha A compound of formula I wherein R1 represents chloro, fluoro or hydroxy as well as optical isomers and racemates thereof as well as pharmaceutically acceptable salts, prodrugs, solvates and crystalline... | 10/02/2007 |
| 7217714 | CCR5 modulators Compounds of Formula 1 [Region α]−[Region β]−[Region γ]−[Region δ] (I) which are useful as modulators of chemokine activity. The invention also provides pharmaceutical formulations and m... | 05/15/2007 |
| 7214695 | Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective... | 05/08/2007 |
| 7166586 | Sulfonamide lactam inhibitors of FXa and method Sulfonamide lactams of the following formula wherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7 and ... | 01/23/2007 |
| 7064124 | NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient A NF-κB inhibitor represented by the following formula (I) is provided: ... | 06/20/2006 |
| 6683142 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators The present invention relates to 1-alkoxy-polyalkyl-piperidine derivatives containing a structural element of formula (I) ##STR1## wherein G1, G2, G3, G4 are independently C1 -C6 alkyl ... | 01/27/2004 |
| 6353107 | 1-alkoxy-polyallkyl-piperidine derivatives and their use as polymerization regulators The present invention relates to 1-alkoxy-polyalkyl-piperidine derivatives containing a structural element of formula (I) ##STR1## wherein G1, G2, G3, G4 are independently C1 -C6 alkyl with... | 03/05/2002 |
| 6303620 | Compounds with growth hormone releasing properties Disclosed are 4,4-disubstituted and 3,3-disubstituted piperidine compounds of formula I ##STR1## wherein D, E, G, J, R1, a, b, c, and d are defined in the specification, compositions containing them, and their use for treating medical diso... | 10/16/2001 |
| 6066642 | Dihydropyridine-, pyridine-, benzopyran-4-one- and triazoloquinazoline derivative, their preparation and their use as adenosine receptor antagonists The present invention provides certain novel compounds, compositions, and a method of treating a mammal by blocking its adenosine receptors comprising administering at least one compound of the present invention. Examples of the present inventive compound... | 05/23/2000 |
| 5907038 | Azepanes Compounds of the formula ##STR1## wherein R1 is phenyl or alpha- or beta-naphthyl, which groups can be substituted by hydroxy, lower-alkyl, lower-alkoxy, lower alkoxycarbonyl, phenoxy, acyloxy, hydroxyphenoxy-sulfonyl, halogen, nitro, amin... | 05/25/1999 |
| 5872131 | Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives The present invention is concerned with novel benzoate derivatives having the formula ##STR1## the N-oxide forms, the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R1 is halo or ... | 02/16/1999 |
| 5856491 | Method of making teritiary hindered amines Fully hindered secondary amines, typically tetramethyl piperidine, are reacted with terminally unsaturated electrophilic compounds having at least five carbon atoms to obtain tertiary hindered amines. The reaction is conducted with an excess of secondary ... | 01/05/1999 |
| 5726313 | Substituted arylaliphatic compounds, method of preparing them and pharmaceutical compositions in which they are present Compound of Formula (I), wherein W1 is an oxygen atom; an --NR-- group wherein R is hydrogen, C1 -C7 alkyl or benzyl; and B is for example a substituted piperidine or quinuclidine. The disclosed compounds are useful as neu... | 03/10/1998 |
| 5594024 | Centrally actig substituted phenylazacycloalkanes A compound or Formula I ##STR1## or a pharmaceutically acceptable salt thereof wherein n is 1 or 2; R1 and R2 are independently H (provided only one is H at the same time), --OH, CN, CH2 CN, 2- or 4-CF3, CH... | 01/14/1997 |
| 5498718 | Preparation of substituted tetrahydropyridines A process for preparing certain 1,3,4,4-tetrasubstituted-1,2,3,4-tetrahydropyridines is provided as well as certain 4-carbonate-1,3,4-trisubstituted piperidines.... | 03/12/1996 |
| 5332817 | 3-aminopiperidine derivatives and related nitrogen containing heterocycles The present invention relates to novel 3-amino-piperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R1, R2, R3, R4, R... | 07/26/1994 |
| 5310902 | Alkylenediamine derivatives Novel alkylenediamine derivatives effectively employable glutamate blockers have the formula (I) or (II): ##STR1## wherein each of R1 and R6 is an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, an aryl group, or an... | 05/10/1994 |
| 5292756 | Novel sulfonamide fibrinogen receptor antagonists A series of non-peptide derivatives of the formula ##STR1## that are antagonists of the fibrinogen IIb/IIIa receptor and thus are platelet anti-aggregation compounds useful in the prevention and treatment of diseases caused by thrombus formation.... | 03/08/1994 |
| 5290888 | Process for stabilizing ethylenically unsaturated compounds and stabilized monomer compositions A process for stabilizing an ethylenically unsaturated monomer or oligomer from premature polymerization is disclosed whereby a stabilizing amount of an N-hydroxy substituted hindered amine is added to said polymerizable monomer or oligomer. The ethylenic... | 03/01/1994 |
| 5206414 | Process for the preparation of hydroxyphenylpropionic acid esters A process for the preparation of compounds of the general formula ##STR1## where R1 and R2 are identical or different and are hydrogen, C1 -C18 alkyl, phenyl, C1 -C4 alkyl-substituted ... | 04/27/1993 |
| 5136040 | Preparation of substituted tetrahydropyridines A process for preparing certain 1,3,4,4-tetrasubstituted-1,2,3,4-tetrahydropyridines is provided as well as certain 4-carbonate-1,3,4-trisubstituted-piperidines.... | 08/04/1992 |
| 5049214 | Aerosol-forming pyrotechonic composition A mixture containing 3,3-bis(aziodomethyloxetane) and EA3834A for use, when gnited, as a physiologically activating agent against enemy personnel on the battlefield by friendly forces.... | 09/17/1991 |
| 4933459 | Pharmaceuticals containing acylated benzilic acid derivatives for influencing the tone of the urinary bladder Certain acylated benzilic acid derivatives are useful for influencing therapeutically the tone of the urinary bladder in humans and animals. These derivatives are N-alkyl-4-piperidyl ,-diphenyl--acyloxyacetates having the formula ... | 06/12/1990 |
| 4855307 | Acetic acid ester of haloperidol The present invention relates to the novel acetic acid ester of 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butano ne, as well as pharmaceutically acceptable acid addition salts thereof, a method of preparation, pharmaceutical compo... | 08/08/1989 |
| 4721722 | Anti-spasmodic agents containing quaternary nitrogen A new class of anti-spasmodic compounds having two branch chains and containing quaternary nitrogen is provided. The compounds have the general formula: ##STR1## wherein R1 and R2 are defined hereinbelow and m is an integer ... | 01/26/1988 |
| 4537698 | Liquid crystalline piperidine derivatives New piperidine derivatives ##STR1## in which R1 and R2 each independently is alkyl or alkoxy each of 1 to 10 C atoms, --Y--Z, F, Cl, Br or CN, and the radical R1 can also be H, Y is --CO--O--, --O--CO or a single bond... | 08/27/1985 |
| 4482561 | Therapeutically effective piperidyl N-(4-quinolyl)-anthraniloyloxyalkanoates The N-substituted-4-(optionally substituted)-2-, 3- or 4-piperidyl N-(7- or 8-substituted-4-quinolyl)-anthraniloyloxyalkanoates having the structural formula (I): ##STR1## in which R is a straight or branched chain alkyl radical having from 1 to ... | 11/13/1984 |
| 4414219 | Antidepressant (-phenyl-2-tolyl)azacycloalkanols and derivatives thereof Novel azacycloalkanes, azacycloalkenes and derivatives thereof and methods of preparing same are described. These compounds are useful as antidepressants, anticonvulsants, tranquilizers and analgetics.... | 11/08/1983 |
| 4308274 | N-Alkylsulfonyl-, N-arylsulfonyl-, and N-aminosulfonylaminosulfinylcarbamate esters A novel class of chemical compounds useful as pesticides consists of N-alkylsulfonyl-, N-arylsulfonyl-, and N-aminosulfonylaminosulfinylcarbamate esters. The preparation of these compounds and their formulation to control insects are exemplified.... | 12/29/1981 |
| 4286095 | 4-Arylpiperidine derivatives A 4-phenyl piperidine having the formula: ##STR1## wherein R1 is a straight chain lower alkyl group; R2 is --COCH3, --COC2 H5 or ##STR2## R3 is --OCOCH3, --OCOC2 | 08/25/1981 |
| 4229207 | Esters of 1,2-diphenyl-cyclohex-1-ene-4-carboxylic acid Esters of 1,2-diphenyl-cyclohex-1-ene-4-carboxylic-acid are effective plant growth regulating agents. They are useful for controlling wild oats in cereal cultures and for growth inhibition in different cultures, e.g. for the inhibition of suckers in tobac... | 10/21/1980 |
| 4205173 | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones, acid addition salts thereof, and intermediate compounds having analgesic properties. A representative quinazolinone compound is 1-[2-(1-phenyl-4-piperazinyl)-ethyl]-2-phenyl-1,2,3,4-tetrahydro-4-quina... | 05/27/1980 |
| 4065565 | Acylhydrazones and anti-psychotic compositions thereof Acylhydrazone compounds having excellent pyschotropic activity which are represented by the formula: ##STR1## wherein Z is selected from the groups having the formulas: ##STR2## wherein n is an integer of from 0 to 2 and R1 -R12 | 12/27/1977 |
| 4060526 | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof 1-heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones, acid addition salts thereof, and intermediate compounds having analgesic properties. A representative quinazolinone compound is 1-[2-(1-phenyl-4-piperazinyl)-ethyl]-2-phenyl-1,2,3,4-tetrahydro-4-quina... | 11/29/1977 |
| 4048314 | Morpholino containing 4-arylpiperidine derivatives The present invention is concerned with novel 4-aryl-3/4-amino/hydroxy-piperidine derivatives of the general formula I: ##STR1## wherein R1 represents hydrogen; lower alkyl; lower aralkyl; lower acyl; aminoalkyl, wherein the alkyl moiety c... | 09/13/1977 |
