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Patent No. 5687752

Dining Table Having Integral Dishwasher

A space-saving dishwasher, which may be installed within a counter top or table, having a dish-carrying rack that is vertically shiftable through the open top of the dishwasher for facilitating loading and unloading of the dishes.

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Class 546/195 - The additional ring is one of the cyclos in a polycyclo ring system


Subclass of Class 546 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which the additional ring is one of the cyclos
No. of patents: 176
Last issue date: 04/14/2009


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NumberTitleIssue Date
7517991N-sulfonylpiperidine cannabinoid receptor 1 antagonists
The present application describes compounds according to Formula I, wherein R1, R2, R3, R4, X and Y are described herein. Additionally, the present application describes pharmaceutical compositions comprising at least one ...
04/14/2009
7432284Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v...
10/07/2008
7378525CCR8 inhibitors
Disclosed are CCR8 inhibitors represented by Structural Formulas (I): The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially a...
05/27/2008
7368462Melanin concentrating hormone antagonists
The present invention relates to compounds capable of serving as moderators of human and mammalian appetite and as such provide a means for reducing body mass and controlling obesity. ...
05/06/2008
RE401837-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
The invention is drawn to 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds of the formula wherein R, X, R5 and R6 are defined in the specification. The compounds of the invention ...
03/25/2008
7329755CCR8 inhibitors
Disclosed is an inhibitor of CCR8 that is represented by Structural Formula (I): Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a CCR8 inhibitor repre...
02/12/2008
7326696Amino-methyl substituted tetracycline compounds
Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed. ...
02/05/2008
7282499Sigma receptor inhibitors
The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to some pyrazole derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use therapy...
10/16/2007
7271264Pentacyclic oxepines and derivatives thereof, compositions and methods
The present invention provides a compound of the formula (I) wherein R1 is —H, —OH, —O(C1-C4 alkyl), —OCOC6H5, —OCO(C1-C6 alkyl), or —OSO2(C2-C6
09/18/2007
7211589Atisane compounds and use thereof
The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the followin...
05/01/2007
7153868N-(3-(4-substituted-1-piperidinyl)-1-phenylpropyl) substituted sulfonamides as NK-3 receptor antagonists
The present invention provides a method of treatment of a subject suffering from a disease, such as schizophrenia, for which the administration of an NK-3 antagonist is indicated which comprises administering to that subject a therapeutically effective amount of a c...
12/26/2006
7144898Indole derivatives for the treatment of depression and anxiety
The present invention provides compounds of formula (I): which are useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from the use of tobacco or of nicotine.
12/05/2006
7132539Melanocortin receptor ligands
The present invention relates to compounds which comprise a nitrogen-containing ring scaffold substituted by an R1 alkyl units selected from the group consisting of C1–C12 linear or branched alkyl, C3–C8 cyc...
11/07/2006
7119206Derivative of dihydro-dibenzo (a) anthracenes and their use as selective estrogen receptor modulators
The present invention provides a compound of the formula (I) wherein R1 is —H, —OH, —O(C1–C4 alkyl), —OCOC6H5, —OCO(C1–C6 alkyl), or —OSO2(C2–C6...
10/10/2006
7105541Naphthyl compounds, intermediates, compositions, and methods of use
The instant invention provides novel substituted naphthyl compounds, intermediates, compositions, pharmaceutical formulations, and methods of use. ...
09/12/2006
7071201Quinoline derivatives
A novel compound of the formula: wherein A, B, C, D, T, Y, and Z represent each methine or nitrogen; R1, R2, R3, R4, and R5 represent each a substituent; n represe...
07/04/2006
7067656Sulfamoyl compounds and agricultural and horticultural fungicides
A sulfamoyl compound of the general formulae (1): wherein R1 and R2 are each independently C1-4 alkyl, or R1 and R2 togeth...
06/27/2006
6995183Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2;
02/07/2006
6906098Mixed steroidal 1,2,4,5-tetraoxane compounds and methods of making and using thereof
Disclosed herein are mixed steroidal tetraoxanes having the following structural formula 1 wherein n is 0, 1, 2, or 3; R is H; ethanoyl, propanoyl, or benzoyl; R1 is H, methyl, ethyl, or isopropyl; R2 is H, methyl, or ...
06/14/2005
6894063Substituted urea neuropeptide Y Y5 Receptor antagonists
A novel class of compounds such as antagonists of the neuropeptide Y Y5 receptor, methods of making such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compou...
05/17/2005
68642664-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists
This invention relates to the (R)-isomers of compounds which are generally muscarinic receptor antagonists and which are represented by Formula I: wherein p, R1, R2, R3 and A are as def...
03/08/2005
6844344Benzofuran derivatives
The present invention provides compounds of formula (I) which are useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from the use of tobacco or of nicotine ...
01/18/2005
6844440Process for the preparation of donepezil
The invention provides a process for the preparation of a compound of the formula 6 comprising the hydrolysis and decarboxylation of a compound of the formula 5 according to the reaction: wherein R and R2 in...
01/18/2005
6838584Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v...
01/04/2005
6800636Farnesyl protein transferase inhibitors
Disclosed are compounds of the formula: wherein R8 represents a cyclic moiety to which is bound an imodazolylalkyl group; R9 represents a carbamate, urea, amide or sulfonamide group; and the remaini...
10/05/2004
6787650Urea compounds, process for producing the same and use thereof
A compound of the formula: [wherein R1 is a hydrocarbon group which may be substituted; R2 is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substitu...
09/07/2004
675637510-Aryl-11h-benzo[b]fluorene derivatives and analogs for medicinal use
The invention provides for a non-steroidal compound having the formula wherein Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2— or —CH2C...
06/29/2004
6730671Compounds useful as reversible inhibitors of cathespin S
Disclosed are cathepsin S reversible inhibitory compounds of the formulas (I),(Ia) and (II),(IIa) as defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes, for making such novel compounds.
05/04/2004
6677355Hydroxamic acid compounds useful as matrix metalloproteinase inhibitors
Compounds of the formula; ##STR1## are useful for inhibiting matrix metalloproteinase enzymes in animals, and as such, prevent and treat diseases resulting from the breakdown of connective tissues. Also disclosed are methods for the preparation of such ...
01/13/2004
6677330Fluorides of 4-substituted piperidine derivatives
The present invention provides a novel compound having an excellent acetylcholinesterase inhibitory effect. That is, it provides a 4-substituted piperidine compound fluoride represented by the following formula, a pharmaceutically acceptable salt thereof ...
01/13/2004
6664253Neurokinin antagonists
The invention relates to new compounds of formula I ##STR1## or the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, X and Ar1 have the meanings given in the specification, as well as...
12/16/2003
6653321Naphthylsulfonic acids and related compounds as glucose uptake agonists
Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptabl...
11/25/2003
6635764Therapeutic ureas
This invention relates to urea compounds that are muscarinic receptor antagonists and agonists, pharmaceutical compositions comprising such compounds, and methods of preparing these compounds....
10/21/2003
66276444-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists
This invention relates to compounds which are generally muscarinic receptor antagonists and which are represented by Formula I: ##STR1## wherein p, R1, R2, R3 and A are as defined in the specification, or individual isomer...
09/30/2003
66080702,3-substituted indole compounds as anti-inflammatory and analgesic agents
This invention provides a compound of the following formula: ##STR1## or the pharmaceutically acceptable salts thereof wherein Z is OH, C1-6 alkoxy, --NR2R3 or heterocycle; Q is selected from the following: (a) an optionally substituted phenyl, (b) an opt...
08/19/2003
6576630Compounds and compositions as protease inhibitors
The present invention relates to novel alkanoyl-substituted heterocyclic derivatives which are cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making....
06/10/2003
6552046Materials and methods for the treatment of gastroesophageal reflux disease
The subject invention provides novel compounds and compositions for the safe and effective treatment of gastroesophageal reflux and related conditions. In a preferred embodiment, the compositions of the subject invention comprise esterified cisapride deri...
04/22/2003
6544987Compounds, compositions, and methods for stimulating neuronal growth and elongation
The present invention concerns methods, pharmaceutical compounds, and compositions for stimulating neuroite outgrowth in nerve cells leading to nerve regeneration. These methods, compounds and compositions inhibit rotamase enzyme activity associated with ...
04/08/2003
6518267Protease inhibitors
The present invention provides bis-aminomethyl carbonyl protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for...
02/11/2003
6511994Modulators of CCR5 chemokine receptor activity
Compounds of Formula I: ##STR1## (wherein R1, R2, R3, R4, Q, and X are defined herein) are described. The compounds are modulators of CCR5 chemokine receptor activity. The compounds are useful, for example, in t...
01/28/2003
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