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| Number | Title | Issue Date |
| 8178676 | Pyridinium boronic acid quenchers for use in analyte sensors Novel pyridinium salts functionalized with boronic acid and methods of making them are disclosed. When combined with a fluorescent dye, the compounds are useful in the detection of polyhydroxyl-substituted organic molecules. ... | 05/15/2012 |
| 8106200 | Pyridine borane complexes The present invention relates to new borane complexes with substituted pyridines, a process for the synthesis of new borane complexes with substituted pyridines, solutions comprising new borane complexes with substituted pyridines and a method of using new borane co... | 01/31/2012 |
| 8003791 | Boronic ester and acid compounds, synthesis and uses Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and... | 08/23/2011 |
| 7968714 | Optical determination of glucose utilizing boronic acid adducts The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particu... | 06/28/2011 |
| 7939664 | Pyridinium boronic acid quenchers for use in analyte sensors Novel pyridinium salts functionalized with boronic acid and methods of making them are disclosed. When combined with a fluorescent dye, the compounds are useful in the detection of polyhydroxyl-substituted organic molecules. ... | 05/10/2011 |
| 7928232 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent. The invention provides a method for producing a compound represented by formula (2): | 04/19/2011 |
| 7718804 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes, such as aqueous chloride and iodide, and a method of using the compounds.... | 05/18/2010 |
| 7678906 | Process for making triphenylboron-pyridine compound A process for improving the recovery of solid triphenylboron-pyridine compound (TPBP), while retaining desirable particle characteristics comprises the addition of an acid to neutralize at least a portion of the alkali contained in the aqueous mother liquor. By adju... | 03/16/2010 |
| 7576206 | Proteasome inhibitors and methods of using the same The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating disease... | 08/18/2009 |
| 7517985 | Process for making solid triphenylboron-pyridine or its adduct A process for producing solid triphenylboron-pyridine (TPBP) spherical particles by separately feeding into a vigorously agitated reaction zone (i) a stream of pyridine and a (ii) stream comprising a solution of sodium hydroxide adduct of triphenylboron (TPBA) where... | 04/14/2009 |
| 7485725 | Substituted pyridines A class of 2,4-; 2,3,4-; 2,4,6-; 2,3,4,5,6-substituted pyridines is provided which include novel compounds. The substitutions are achieved according to methods disclosed herein in which a metallated pyridine is reacted with an electrophile. Suitable electrophiles in... | 02/03/2009 |
| 7442797 | Platinum complex and light emitting device Provision of a novel platinum complex which is useful as a material for a light-emitting device of good light emission characteristic and light emission efficiency, and a novel light-emitting material that may be utilized in various fields. A platinum complex... | 10/28/2008 |
| 7390806 | Antibiotics containing borinic acid complexes and methods of use The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions... | 06/24/2008 |
| 7365201 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid A process for the preparation of the boron difluoride chelate of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolone carboxylic acid via: (a) the reaction of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-q... | 04/29/2008 |
| 7348428 | Triarylamine containing monomers for optoelectronic devices Monomers having the formula X1—Ar1-[triarylamine]—Ar2-X2 wherein the triarylamine unit comprises at least one nitrogen atom in the backbone of the monomer and at least three substituted or unsubstituted aryl or heteroa... | 03/25/2008 |
| 7320885 | Method of perforating membrane and apparatus therefor A method of perforating a membrane 10 is presented. The method comprises: bringing a membrane-denaturing substance into contact with or close proximity to at least a site of said membrane 10, said substance inducing a membrane-denaturing reaction by a ... | 01/22/2008 |
| 7291581 | Borate ester lubricant additives Disclosed are borate and boronate compounds of the formulae where R1, R2 and R3 are independently hydrogen, straight or branched chain alkyl of 1 to 24 carbon atoms, strai... | 11/06/2007 |
| 7279487 | Hydroxynaphthyridinone carboxamides useful as HIV integrase inhibitors Hydroxynaphthyridinone carboxamides of formula: are described as inhibitors of HIV integrase and inhibitors of HIV replication, wherein L, R1a, R1b, R1c, R2a, R2b | 10/09/2007 |
| 7267891 | Compound for light emitting device and organic light emitting device using the same An organic EL device according to the present invention has a layered structure in which a hole injection electrode (anode), a hole injection layer, a hole transport layer, a light emitting layer, a hole blocking layer, an electron injection layer, and an electron i... | 09/11/2007 |
| 7250470 | Crystallization of polypropylene using a semi-crystalline, branched or coupled nucleating agent A method of nucleating a propylene homo- or copolymer, the method comprising contacting the propylene polymer with a semi-crystalline branched or coupled polymeric nucleating agent under nucleation conditions. In one embodiment, the propylene homopolymer is characte... | 07/31/2007 |
| 7220732 | Compounds useful as photodynamic therapeutic agents The present invention relates to compounds of the formula or a salt, metal complex or hydrate or other solvate thereof, wherein: M is a chelating agent; R1, R2, R | 05/22/2007 |
| 7199203 | Isotactic propylene copolymer fibers, their preparation and use Fibers comprising a propylene homopolymer or a copolymer of propylene and at least one of ethylene and one or more unsaturated comonomers exhibit desirable properties. The homopolymers are characterized as having 13C NMR peaks corresponding to a regio-err... | 04/03/2007 |
| 7122699 | Process for preparing organic boronic acid derivatives using diboronic acid The invention relates to a process for the preparation of organic boronic acid derivatives involving the reaction of an organic compound with diboronic acid in the presence of a Group 8-11 metal catalyst. ... | 10/17/2006 |
| 7119080 | Boronic ester and acid compounds, synthesis and uses Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and... | 10/10/2006 |
| 7112572 | Multivalent metal salts of boronic acids Salts of a pharmaceutically acceptable divalent metal and an organoboronic acid drug. Examples of such metals are calcium, magnesium and zinc. The organoboronic acid drug may be a boropeptide protease inhibitor. The salts may be formulated in oral dosage form. ... | 09/26/2006 |
| 7105467 | Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives The present invention provides nickel catalysts and solvents which are useful in a cross-coupling reaction between an organomagnesium compound and an aromatic ether compound, such as an anisole derivative. ... | 09/12/2006 |
| 7087755 | Substituted pyridines A class of 2,4-; 2,3,4-; 2,4,6-; 2,3,4,5,6-substituted pyridines is provided which include novel compounds. The substitutions are achieved according to methods disclosed herein in which a metallated pyridine is reacted with an electrophile. Suitable electrophiles in... | 08/08/2006 |
| 7084403 | Scintillator compositions, and related processes and articles of manufacture Scintillator materials based on certain types of halide-lanthanide matrix materials are described. In one embodiment, the matrix material contains a mixture of lanthanide halides, i.e., a solid solution of at least two of the halides, such as lanthanum chloride and ... | 08/01/2006 |
| 7071175 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors The present invention relates to compounds of Formula I, and pharmaceutically acceptable salts or solvates thereof, or solvates of such salts, which compounds inhibit carboxypeptidase U and thus can be used in the prev... | 07/04/2006 |
| 7060754 | Crystallization of polypropylene using a semi-crystalline, branched or coupled nucleating agent A method of nucleating a propylene homo- or copolymer, the method comprising contacting the propylene polymer with a semi-crystalline branched or coupled polymeric nucleating agent under nucleation conditions. In one embodiment, the propylene homopolymer is characte... | 06/13/2006 |
| 7053079 | Dihydroxy (3-pyridyl) borane compounds A dihydroxy(3-pyridyl)borane compound of the formula (1): wherein R1 represents a hydrogen atom, halogen atom or alkoxycarbonylamino group; R2 represents a hydrogen atom, halogen atom, alkyl... | 05/30/2006 |
| 7041765 | Films comprising isotactic propylene copolymers Films with excellent machine direction (MD) tear properties comprise at least one layer made from a polymer comprising: (A) at least 50 weight percent (wt%) propylene; and (B) at least 5 wt % ethylene and/or one or more unsaturated comonomers. Represen... | 05/09/2006 |
| 7026490 | Amorphous organic 1,3,2-dioxaborine luminophores, method for the production and use thereof The invention relates to luminophores having semiconducting properties and to the production and use thereof in organic luminous diodes (OLEDS) and organic solar cells. The novel materials are easy to prepare and exhibit excellent current density and efficiency when... | 04/11/2006 |
| 6976537 | Method for decreasing lost circulation during well operation A method is provided for reducing lost circulation when aqueous, oil, or synthetic based drilling fluid is used. The method includes injecting two fluids into the well bore and lost circulation zone. The first fluid is an aqueous liquid containing at least one polym... | 12/20/2005 |
| 6964966 | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydr... | 11/15/2005 |
| 6960635 | Isotactic propylene copolymers, their preparation and use Unique copolymers comprising propylene, ethylene and/or one or more unsaturated comonomers are characterized as having: at least one, preferably more than one, of the following properties: (i) 13C NMR peaks corresponding to a regio-error at about 14.6 and... | 11/01/2005 |
| 6946535 | Films comprising isotactic propylene copolymers Films with excellent machine direction (MD) tear properties comprise at least one layer made from a polymer comprising: (A) at least 50 weight percent (wt %) propylene; and (B) at least 5 wt % ethylene and/or one o... | 09/20/2005 |
| 6939985 | Aryl borates The invention provides a process for covalently coupling organic compounds which comprises reacting an aromatic ring compound having a halogen or halogen-like substituent at a coupling position with a diboron derivative in the presence of a Group VIII metal catalyst... | 09/06/2005 |
| 6929869 | Organic light emitting material and device Organic light emitting diode devices having a substrate bearing an organic layer sandwiched between electrode structures. The organic layer includes, in a single layer a hole transporter, an electron transporter and a light emitter where the electron transporter or ... | 08/16/2005 |
| 6927258 | Elastic blends comprising crystalline polymer and crystallizable polymers of propylene Improved thermoplastic polymer blend compositions comprising an isotactic polypropylene component and an alpha-olefin and propylene copolymer component, said copolymer comprising crystallizable alpha-olefin sequences. In a preferred embodiment, improved thermoplasti... | 08/09/2005 |
