Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 7153968 | 8-(biaryl)quinoline PDE4 inhibitors 8-(biaryl) quinolines wherein the bi-aryl group at the 8-position is in a meta relationship to the quinoline group, are PDE4 inhibitors useful in the treatment of asthma, chronic bronchitis, chronic obstructive pulmonary disease, eosinophilic granuloma, psoriasis an... | 12/26/2006 |
| 7122671 | Luminescent labelling materials and procedures A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or other protein and is used in a two-site immunoassay for the quantitat... | 10/17/2006 |
| 7087395 | Vitamin D assay The present invention features a kit and a method of using the kit for determining a concentration of a vitamin D component. The kit comprises a releasing composition and a detecting composition. The releasing composition comprises an aqueous base component. In one ... | 08/08/2006 |
| 7083986 | Near infrared chemiluminescent acridinium compounds and uses thereof A method for the detection or quantitation of an analyte in a biological sample is disclosed. The method comprises the steps of selecting a biological sample suspected of containing a target analyte and binding the target analyte in the sample to a binding partner c... | 08/01/2006 |
| RE39047 | Luminescence by reacting an acridinium ester with superoxide A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light emitted by reacting a superoxide anion with an acridinium ester used ... | 03/28/2006 |
| 6925392 | Method for measuring fluid chemistry in drilling and production operations A method for chemical analysis of fluids utilized in hydrocarbon exploration and production in which microfluidic systems designed to react to specific characteristics of a fluid are introduced into fluid samples or during operations. The microfluidic systems are th... | 08/02/2005 |
| 6872828 | Compounds for generating chemiluminescence with a peroxidase Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a pe... | 03/29/2005 |
| 6858733 | Compounds for generating chemiluminescence with a peroxidase Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a pe... | 02/22/2005 |
| 6743817 | Substituted fused pyrroleimines and pyrazoleimines Disclosed are compounds of the formula and the pharmaceutically acceptable salts thereof wherein R, Ar, A, n, R1 and R2 are defined herein. These compounds are highly selective agonists, antagonists... | 06/01/2004 |
| 6414152 | Luminescent labelling material and procedures A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or other protein and is used in a two-site immunoassay for th... | 07/02/2002 |
| 6015902 | Intercalators having affinity for DNA and methods of use Intercalator compounds of formula I-Tm as defined herein are provided which are comprised of intercalator moieties, or substituted intercalator moieties, having one or more functionalized chains, or moieties, and which compounds provide a high ... | 01/18/2000 |
| 6002007 | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays Chemiluminescent acridinium derivatives of the formula I ##STR1## in which R4 represents a radical of the formula II or III ##STR2## and Aθ, X--, R1 -R3, R5 and R6 have the state... | 12/14/1999 |
| 5879888 | Light emitting method of acridinium derivative and method of detecting substance to be examined using same A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light emitted by reacting a superoxide anion with an acridinium ... | 03/09/1999 |
| 5565554 | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores Novel fluorescent DNA-staining dyes are provided combining asymmetric cyanine azole-indolenine dyes, which provide for strong DNA affinity, large Stokes shifts and emission in the red region of the spectrum. The dyes find particular application in gel ele... | 10/15/1996 |
| 5538901 | Nucleophilic polysubstituted aryl acridinium ester conjugates uses thereof This invention is directed to the novel assay methods utilizing nucleophilic polysubstituted aryl acridinium ester conjugates as the tracers. Conjugates prepared by covalent coupling of novel nucleophilic polysubstituted aryl acridinium esters with biolog... | 07/23/1996 |
| 5455252 | Optionally substituted 6,8-quinolines A compound of the formula ##STR1## wherein: R1 is independently selected from hydrogen, lower-alkyl, cycloalkyl, cycloalkyl lower-alkyl, lower-alkoxy, formyl, (lower-alkyl)-hydroxylmethyl, aryl, benzyl, arylmethyl, pyridylmethyl, where ary... | 10/03/1995 |
| 5449556 | Method for detection of an analyte using acridinium esters and liposomes A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesic... | 09/12/1995 |
| 5401847 | DNA complexes with dyes designed for energy transfer as fluorescent markers Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of flu... | 03/28/1995 |
| 5338847 | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation Described are a class of chemiluminescent compound characterized by the presence an aryl ester, thioester or amide of a carboxylic acid substituted heterocyclic ring that is susceptible to chemical attack (such as by oxidic attack) to dissociate the heter... | 08/16/1994 |
| 5321136 | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom A chemiluminescent label compound and conjugate containing the same, in which the compound involves a fused ring system comprising a (i) hetercyclic ring as a fused member thereof in which the heterocyclic ring contains (a) one or more nitrogen heteroatoms in ... | 06/14/1994 |
| 5290936 | Nitro substituted chemiluminescent labels and their conjugates, and assays therefrom A novel chemiluminescent labeling compositions comprising an ester, thiolester or amide covalently and jointly bonded to (1) a carbon of a heterocyclic ring or ring system that is susceptible to attack by peroxide or molecular oxygen and (2) an aryl ring ... | 03/01/1994 |
| 5284951 | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom A novel chemiluminescent labeling compositions comprising an ester, thioester or amide covalently and jointly bonded to (1) a carbon of a heterocyclic ring or ring system that is susceptible to attack by peroxide or molecular oxygen and (2) an aryl ring o... | 02/08/1994 |
| 5284952 | Sulfonyl substituted chemiluminescent labels and their conjugates, and assays therefrom A chemiluminescent labeling composition comprising an ester, thioester or amide covalently and jointly bonded to (1) a carbon of a heterocyclic ring or ring system that is susceptible to attack by peroxide or molecular oxygen and (2) an aryl ring or ring ... | 02/08/1994 |
| 5283334 | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom A chemiluminescent compound possessing an aryl ester, thioester or amide of a carboxylic acid substituted heterocyclic ring or ring system that is susceptible to chemical attack to dissociate the heterocyclic ring to a transient compound. The heterocyclic... | 02/01/1994 |
| 5281712 | Ammonium substituted chemiluminescent labels and their conjugates, and assays therefrom A novel chemiluminescent labeling compositions comprising an ester or thiolester covalently and jointly bonded to (1) a carbon of a heterocyclic ring or ring system that is susceptible to attack by peroxide or molecular oxygen and (2) an aryl ring or ring... | 01/25/1994 |
| 5241070 | Nucleophilic polysubstituted aryl acridinium esters and uses thereof This invention is directed to novel nucleophilic polysubstituted aryl acridinium esters and to novel conjugates thereof. The novel nucleophilic polysubstituted aryl acridinium esters and novel conjugates thereof are useful in biological assays, including ... | 08/31/1993 |
| 5227489 | Stable hydrophilic acridinium esters suitable for liposome encapsulation A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesic... | 07/13/1993 |
| 5155216 | Nucleic acids labeled with a chemiluminescent acridine ester Polynucleotides are labeled with chemiluminescent acridine esters or luminescent lanthanides. Labelling is preferably carried out by incorporating a functional group into a nucleotide or polynucleotide at the C4 position of the pyrimidine portion or the C... | 10/13/1992 |
| 5151518 | N-arylation of isatins A process for the N-arylation of isatins with organo bismuth reagents is disclosed.... | 09/29/1992 |
| 5120745 | 1-dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles This invention relates to 1-dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles of the formula ##STR1## wherein the substituents are as defined herein, compositions containing those compounds and methods of use.... | 06/09/1992 |
| 5110932 | Polysubstituted aryl acridinium esters The present invention relates to novel acridinium esters which are useful as luminescent labels in specific binding assays such as immunoassays or nucleic acid hybridization assays. More particularly, polysubstituted aryl acridinium esters are highly stab... | 05/05/1992 |
| 5086179 | Process for the preparation of optically pure amides This invention is directed to certain dibenzofurancarboxamides and dibenzofurancarboxamide acids and their use as 5HT3 antagonists having unique CNS, anti-emetic and gastric prokinetic activity void of any significant D2 receptor bin... | 02/04/1992 |
| 5075556 | Acridine orange derivatives and their use in the quantitation of reticulocytes in whole blood Quaternized derivatives of acridine orange and reagents incorporating such derivatives and their use in quantitatively determining reticulocyte levels in whole blood specimen by fluorescence flow cytometry techniques are disclosed. The quaternized derivat... | 12/24/1991 |
| 5049673 | Fluorescent indicator dyes for calcium working at long wavelengths The present invention discloses a new class of calcium specific fluorescent indicator dyes having visible excitation and emission wavelengths. The new fluorescent indicator dyes combine at least one tricyclic chromophore with a tetracarboxylate parent CA | 09/17/1991 |
| 5013741 | N-[substituted alkylidene]-1,2,3,4-tetrahydro-9-acridinamines useful for enhancing the cholinergic function in a mammal There are disclosed compounds having the formula ##STR1## wherein n is 1-4; R1 is hydrogen, alkyl, aryl, arylloweralkyl, naphthyl, furyl, thienyl, pyridinyl or pyrrolyl; X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy ... | 05/07/1991 |
| 4946958 | Chemiluminescent acridinium labelling compounds A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or other protein and is used in a two-site immunoassay for th... | 08/07/1990 |
| 4918192 | Polysubstituted aryl acridinium esters The present invention relates to novel acridinium esters which are useful as luminescent labels in specific binding assays such as immunoassays or nucleic acid hybridization assays. More particularly, polysubstituted aryl acridinium esters are highly stab... | 04/17/1990 |
| 4861564 | Method of use of 1,3 disubstituted aromatic cyclohexane imides as chelating agents The compounds of the invention comprise the condensation product, as well as derivatives thereof, of two equivalents of a trimethyl cyclohexane-anhydride acid chloride derivative with one equivalent of an aromatic diamine. The scope of the invention inclu... | 08/29/1989 |
| 4851536 | Cyclohexylquinolines as inhibitors of interleukin 1 There are disclosed compounds of the formula ##STR1## wherein X is O, S, SO, SO2 or CR1 R2 ; R1 and R2 are each independently hydrogen, lower alkyl, carboxyl, lower alkoxy carbonyl, lower cycloalkyl, ... | 07/25/1989 |
| 4822878 | Cyclic anhydride derivatives of chromophors Novel chromophor derivatives of cyclic anhydrides are provided which have the ability to react with a variety of organic substrates forming adducts which are useful in analytical techniques for the detection and measurement of biological compounds.... | 04/18/1989 |
