Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 8053572 | Alkyl-analide producing method The present invention relates to a process for preparing known fungicidally effective alkylanilides from acid chlorides and aminoacetophenone via hydroxyalkyl-substituted carboxanilides, alkenylanilides and benzoxazine derivatives. ... | 11/08/2011 |
| 7872123 | Process of making α-aminooxyketone/α-aminooxyaldehyde and α-hydroxyketone/α-hydroxyaldehyde compounds and a process making reaction products from cyclic α,β-unsaturated ketone substrates and nitroso substrates The present invention is directed to a process of making α-aminooxyketone and α-hydroxyketone compounds. The synthetic pathway involves reacting an aldehyde or ketone substrate and a nitroso substrate in the presence of a catalyst of the formula (IV): | 01/18/2011 |
| 7622579 | Hetero isonipecotic modulators of vanilloid VR1 receptor This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals. ... | 11/24/2009 |
| 7408060 | Nonsteroidal progesterone receptor modulators This invention relates to nonsteroidal progesterone receptor modulators of general formula I, a process for their production, the use of progesterone receptor modulators for the production of pharmaceutical agents as well a... | 08/05/2008 |
| 7388006 | Non-steroidal progesting The present invention relates to non-steroidal progestins of the general formula (I) wherein R1 and R2 are independently of each other —H or —F, R3 is —CH | 06/17/2008 |
| 7361756 | Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril The invention encompasses synthesizing 7-(4-bromobutoxy)-3,4-dihydrocarbostyril by mixing 7-hydroxy-tetrahydroquinolinone, dibromobutane, and at least one base to form a reaction mixture; heating the reaction mixture; cooling the reaction mixture; and isolating the ... | 04/22/2008 |
| 7361755 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines This invention pertains to a novel process for preparing sterically hindered N-substituted alkyloxyamines from alkenes by the transition-metal-catalyzed reaction of a intermediate alkylborane with a sterically hindered nitroxyl radical. ... | 04/22/2008 |
| 7348328 | MCH antagonists for the treatment of obesity The present invention discloses compounds which, are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonist... | 03/25/2008 |
| 7332511 | Vanilloid receptor ligands and their use in treatments Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular an... | 02/19/2008 |
| 7329288 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof The present disclosure relates to a novel family of N-heteroaryl secondary para-phenylenediamines, to their preparation, to their use for dyeing the hair and to a dye composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprisi... | 02/12/2008 |
| 7312214 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors The present application describes 1,1-disubstituted cycloalkyl compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa. ... | 12/25/2007 |
| 7301028 | Mitotic kinesin inhibitors The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which com... | 11/27/2007 |
| 7259163 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors Novel anti-viral agents of Formula wherein: A represents OR1, NR1R2, or R1 wherein R1 and R2 are hydrogen, C1-6alkyl, aryl... | 08/21/2007 |
| 7196108 | Bicyclic heterocycles for the treatment of diabetes and other diseases The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, and atherosclerosis. | 03/27/2007 |
| 7183238 | [1,2]-oxazine-3,5-diones The present invention relates to novel [1,2]-oxazine-3,5-dione derivatives of the formula (I) in which W, X, Y, Z, G, D, A and B are as defined in the disclosure, to a pl... | 02/27/2007 |
| 7166609 | Pyrimidine-4,6-dicarboxylic acid diamides for selectively inhibiting collagenases Pyrimidine-4,6-dicarboxylic acid diamides of the formula I are suitable for selectively inhibiting collagenase (MMP 13). The pyrimidine-4,6-dicarboxylic acid diamides can therefore be used for treating degenerati... | 01/23/2007 |
| 7125989 | Hetero diels-alder adducts of pentacene as soluble precursors of pentacene The present invention describes organic solvent-soluble Diels-Alder adducts of polycyclic aromatic compounds, such as, oligothiophene, perylene, benzo[ghi]perylene, coronene and polyacenes, with variety of dienophiles containing at least one heteroatom and in some c... | 10/24/2006 |
| 7115646 | Cyclic diamines and derivatives as factor Xa inhibitors The present application describes cyclic diamino compounds, derivatives thereof, and pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa. ... | 10/03/2006 |
| 7112584 | Nonsteroidal antiinflammatory agents The invention relates to compounds of general formula I and their use for the production of pharmaceutical agents for treatment and prophylaxis of diseases that coincide with inflammatory, allergic and/or prolife... | 09/26/2006 |
| 7105661 | Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences The invention relates to the use of morpholino-nucleosides of formula: in which R1 represents a nucleic base and R2 represents a group corresponding to one of the following formulae: | 09/12/2006 |
| 7081526 | Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences The invention relates to the use of morpholino-nucleosides of formula: in which R1 represents a nucleic base and R2 represents a group corresponding to one of the following formulae: | 07/25/2006 |
| 7053138 | Flame-proofing agents Compounds of formula (I) or (II), wherein R1 is C1–C18alkyl; C5–C12cycloalkyl that is unsubstituted or substituted by one or more C1–C6alkyl groups or C1–C6alk... | 05/30/2006 |
| 7053109 | Aminediols for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the... | 05/30/2006 |
| 7029654 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors Aminoguanidine and alkoxyguanidine compounds are described, including compounds of the Formula VII: wherein X is O or NR9 and Het, R1, R7, R8, R12—R15,... | 04/18/2006 |
| 7030110 | Cyclic oxyguanidine pyrazinones as protease inhibitors Cyclic oxyguanidine pyrazinone compounds are described, including compounds of the Formula I: wherein R3, R4, R5, W, and A are as set forth in the specification, as well as hydrates, sol... | 04/18/2006 |
| 7030238 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from about 225 to about 1,000 (from about 225 to about 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon a... | 04/18/2006 |
| 7001918 | 7-pyrrolyl tetracycline compounds and methods of use thereof A compound of Formula (I): wherein variables R, R1, R2, R3 and A are as defined in the ... | 02/21/2006 |
| 6960581 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof A compound of Formula (I) wherein R1, R2, R3, R4, R5, and R6 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof, pharmaceutical com... | 11/01/2005 |
| 6911477 | Muscarinic receptor agonists This invention relates to a novel class of partial or full muscarinic receptor agonists intermediates for their preparation, and pharmaceutical compositions and methods of use for the treatment or prevention of diseases the treatment or prevention of which is mediat... | 06/28/2005 |
| 6894005 | Herbicides Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomer of those compounds, are suitable for use as herbicides. ... | 05/17/2005 |
| 6887994 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from about 225 to about 1,000 (from about 225 to about 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon a... | 05/03/2005 |
| 6875831 | Mono and multifunctional alkoxyamines for the preparation of functionalized macromers The invention pertains to a compound of formula (I), (II) or (III) wherein R1 and R2 are independently of each other hydrogen, C1-C18alkyl, C3-C18alkeny... | 04/05/2005 |
| 6861432 | Piperazine derivatives that destabilize androgen receptors This invention relates to new piperazine derivatives of general formula I, in which V, W, n, R, R′, i, j, Y and Z have the meaning that is indicated in the description. The compounds according to the inventio... | 03/01/2005 |
| 6861416 | Oxazinones and methods for their use and synthesis The invention pertains, at least in part, to new intermediates and synthetic methods for the stereospecific synthesis of oxazinone compounds, which are useful, for example, as antibiotics. The invention also pertains to novel olefinic oxazinone compounds, methods fo... | 03/01/2005 |
| 6838560 | Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences The invention relates to the use of morpholino-nucleosides of formula: in which R1 represents a nucleic base and R2 represents a group corresponding to one of the following formulae: ... | 01/04/2005 |
| 6828276 | Herbicidally active benzoylcyclohexanediones There are described benzoylcyclohexanediones of the formula I, their preparation, and their use as herbicides and plant growth regulators. In this formula (I), C1, C2, C3 are cyclic radic... | 12/07/2004 |
| 6787522 | Antibacterial agents Compounds of formula (I) are antibacterials: wherein: R1 represents hydrogen, or C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 ... | 09/07/2004 |
| 6777409 | Nonsteroidal antiinflammatory agents The compound of formula 1 useful in the treatment of inflammation. ... | 08/17/2004 |
| 6777404 | Use of corticotropin releasing factor antagonists and related compositions The present invention relates to compositions and methods of achieving a therapeutic effect including, the treatment or prevention of Syndrome X in an animal, preferably a mammal including a human subject or a companion animal, using a corticotropin releasing factor... | 08/17/2004 |
| 6734143 | 2-methoxyimino-2(pyridinyloxymethyl)phenyl acetamides useful as fungicides The present invention provides 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides according to formula (I) as well as their use as fungicidal compounds. ... | 05/11/2004 |
