Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7872124 | Dipeptidyl peptidase inhibitors Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a member selected from the group consisting of: wherein E is CH or N, Q is selected from the group consistin... | 01/18/2011 |
| 7692011 | 8-hydroxy and 8-mercapto quinazolinones The present invention relates to neurologically active 8-hydroxy- or 8-mercapto-quinazolinones. Also disclosed are processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological ... | 04/06/2010 |
| 7442794 | Rearranged pentanols, a process for their production and their use as anti-inflammatory agents The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents. ... | 10/28/2008 |
| 7439246 | Fused heterocyclic kinase inhibitors In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful... | 10/21/2008 |
| 7420056 | Substituted bicyclic imidazo-3-ylamine compounds Substituted bicyclic imidazo-3-yl-amine compounds are provided, as well as processes for the production thereof and pharmaceutical formulations containing these compounds. The use of these compounds for the production of pharmaceutical formulations and related metho... | 09/02/2008 |
| 7375102 | Tetrahydroquinazolin-4(3H)-one-related and tetrahydropyrido[2,3-]pyrimidin-4(3H)-one-related compounds, compositions and methods for their use Compounds are provided having the formula: wherein variables A1, A2, A3, A4, R1, R2, R3, R4, Q and L are as described herein. The subje... | 05/20/2008 |
| 7365199 | Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound A dye-forming coupler of formula (I), a silver halide photographic light-sensitive material containing the coupler, and an azomethine dye compound derived from the coupler: wherein Q is a residue that forms, together with t... | 04/29/2008 |
| 7365066 | Pyrazolopyridine derivatives as pharmaceutical agents Novel pyrazolopyridine derivative compounds are disclosed and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors useful in the treatment of cancer and other disease states influenced by TGF beta. ... | 04/29/2008 |
| 7321033 | 3-B-D-ribofuranosylthiazolo [4,5-] pyrimidine nucleosides and uses thereof The invention is directed to 3-β-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compou... | 01/22/2008 |
| 7312180 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines A description is given of 4-(4-trifluoromethylpyrazolyl)pyrimidines of the formula (I) and of their use as herbicides. In this general formula (I), R1, R2, R3 and R4 are ... | 12/25/2007 |
| 7307168 | Process for the preparation of 3-{2-′4- (6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyllethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido′1,2-methyl-4h-pyrido′,2-a!pyrimidin-4-one The invention relates to a process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl}-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one of the Formula (I), and pharmaceutically acceptable acid addition salts thereof by sub... | 12/11/2007 |
| 7297700 | Bicycloheteroaryl compounds as P2X modulators and uses thereof Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of cond... | 11/20/2007 |
| 7276570 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These compositions comprise at least one polymer having a plurality of amide linkages and a plurality of anionic moieties attached thereto. These co... | 10/02/2007 |
| 7265195 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These compositions comprise at least one polymer having a plurality of amide linkages and a plurality of cationic moieties attached thereto. These c... | 09/04/2007 |
| 7256249 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. The compositions comprise at least one regioselective polyisocyanate having an asymmetric structure and comprising at least a first NCO group and a ... | 08/14/2007 |
| 7256287 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-aza-benzimidazole molecules tha... | 08/14/2007 |
| 7253168 | Substituted 1-benzyl-4-substituted piperazine analogues Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment... | 08/07/2007 |
| 7253245 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These elastomer compositions comprise reaction products of polyisocyanates and telechelic polymers having isocyanate-reactive end-groups such as hyd... | 08/07/2007 |
| 7253242 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable materials are presently disclosed. The materials have a rebound height percentage of greater than 60% and are formed from compositions comprising at least one resilient polyamine polydiene and/or ... | 08/07/2007 |
| 7238698 | Substituted quinazoline compounds useful as p38 kinase inhibitors Compounds having the formula (I), are useful as p38 kinase inhibitors, wherein R4 and R5 are hydrogen, halogen, cyano, haloalkyl, or haloalkoxy, but are not both hydrogen; R6 and ... | 07/03/2007 |
| 7232902 | Process to prepare (1-carboxymethyl)-pyrimidinone compounds The invention relates to a process for the preparation of certain pyrimidinone compounds. ... | 06/19/2007 |
| 7223766 | Bi-cyclic pyrimidine inhibitors of TGFβ Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with rheumatoid arthritis ameliorated by inhibition of TGFβ ac... | 05/29/2007 |
| 7223767 | Tetrahydroquinazolines and dihydrocyclopentapyrimidines as CRF antagonists Compounds of the formula (I): and pharmaceutically acceptable salts or prodrugs thereof, wherein m, R1, R2, R3, R4, R5 and R6 are as defined herei... | 05/29/2007 |
| 7220750 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them The present invention relates to bicyclic heterocycles of general formula wherein Ra to Rc, A to E and X are defined as in claim 1, the tautomers, stereoisomers and salts thereof, pa... | 05/22/2007 |
| 7214800 | Compounds, compositions, and methods Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed. ... | 05/08/2007 |
| 7196091 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them The present invention relates to bicyclic heterocycles of general formula wherein Ra, Rb, Rc, Rd, X and n are defined as in claim 1, the tautomers, ... | 03/27/2007 |
| 7192949 | Substituted bicyclic pyrimidinones as a mitotic kinesin KSP inhibitors The present invention relates to cycloalkylpyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions wh... | 03/20/2007 |
| 7193080 | Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound A dye-forming coupler and compound of formula (I): wherein Q represents a residue that forms, together with —N—C═N—, a nitrogen-containing 6-membered ring; RA represents an aryl, heterocyclic, ... | 03/20/2007 |
| 7176310 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents This invention is directed to compound of the following formula (I): wherein R1, R2, R3 and R4 are as described herein. These compounds and pharmaceutical compositions ... | 02/13/2007 |
| 7169916 | Chloral-free DCA in oligonucleotide synthesis A process of manufacturing oligonucleotides includes a 5′-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chlora... | 01/30/2007 |
| 7169924 | Pyrimidinone derivatives and their use in the treatment of atherosclerosis Compound of formula (I): are disclosed in which: R1 is an aryl group, optionally substituted by 1, 2, 3 or 4 substituents which may be the same or different selected ... | 01/30/2007 |
| 7166595 | Compounds, methods and compositions Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed. ... | 01/23/2007 |
| 7166726 | Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br... | 01/23/2007 |
| 7160890 | Compounds specific to adenosine Areceptor and uses thereof This invention pertains to compounds which specifically inhibit the adenosine A3 receptor and the use of these compounds to treat a disease associated with A3 adenosine receptor in a subject, comprising administering to the subject a therapeuti... | 01/09/2007 |
| 7161002 | Syntheses of quinazolinones The present invention provides novel quinazolinone compositions of matter comprising enantiomerically pure compound represented by Formula I: or a pharmaceutically acceptable salt thereof, having a detectable amo... | 01/09/2007 |
| 7160889 | Quinazoline compounds The invention concerns quinazoline derivatives of Formula (I) wherein ring A is phenyl or a 5-or 6-membered heterocyclic ring which may be saturated, partially saturated or unsaturated and may be aromatic or non-... | 01/09/2007 |
| 7157545 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These elastomer compositions comprise reaction products of polyisocyanates and telechelic polymers having isocyanate-reactive end-groups such as hyd... | 01/02/2007 |
| 7153861 | 5,6 -Trimethylenepyrimidin-4-one compounds Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use is treating atheroscelerosis. ... | 12/26/2006 |
| 7138476 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These compositions comprise at least one fatty compound chosen from fatty polyamines and fatty polyamine telechelics. These elastomer compositions c... | 11/21/2006 |
| 7138475 | Compositions for golf equipment Golf balls comprising thermoplastic, thermoset, castable, or millable elastomer compositions are presently disclosed. These elastomer compositions comprise at least one amine-terminated polyamide and at least one isocyanate-containing prepolymer. These elastomer com... | 11/21/2006 |