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| Number | Title | Issue Date |
| 7910733 | Image-forming material The image-forming material includes a perimidine-based squarylium dye represented by the following formula (I): ... | 03/22/2011 |
| 7741482 | Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. ... | 06/22/2010 |
| 7692009 | Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. ... | 04/06/2010 |
| 7692008 | Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. ... | 04/06/2010 |
| 7692010 | Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. ... | 04/06/2010 |
| 7407964 | Caspase inhibitors and uses thereof This invention provides novel caspase inhibitors of formula I: wherein R1 is hydrogen, CHN2, R, or —CH2Y; R is an aliphatic group, an aryl group, an aralkyl group, a heterocyclyl group, or... | 08/05/2008 |
| 7345049 | Phenylalanine derivatives Specific phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin. ... | 03/18/2008 |
| 7326257 | Composition for dyeing keratinous fibers comprising at least one azodiazine direct dye which is non-aminated at the 7-position and dyeing method using said at least one azodiazine direct dye Disclosed herein is a composition for dyeing keratinous fibers, comprising at least one direct dye corresponding to the following formula (I): in which R1 and R2 may be chosen from hydrogen ... | 02/05/2008 |
| 7319103 | Non-imidazole tertiary amines as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain non-imidazole tertiary amine de... | 01/15/2008 |
| 7297701 | Anti-cancer cyclopenta [G]quinazoline compounds Cyclopenta[g]quinazolines of the formula (I):—wherein: A is a group OR or NR0R1 wherein R0 and R1 are each independently hydrogen C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl, C2-4 h... | 11/20/2007 |
| 7270684 | Composition for dyeing keratinous fibers comprising at least one azodiazine direct dye containing an aniline group and dyeing method using it The present invention relates to a composition for dyeing keratinous fibers, containing at least one azodiazine direct dye corresponding to the following formula (I): The present invention also relates to a metho... | 09/18/2007 |
| 7262297 | Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals. ... | 08/28/2007 |
| 7244844 | Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. ... | 07/17/2007 |
| 7230139 | Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid... | 06/12/2007 |
| 7217717 | Phenalene derivatives Novel 1,3,4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives are disclosed. These compounds inhibit epidermal growth factor receptor (“EGFR”) tyrosine kinase. These compounds and their pharmaceutically acceptable salts and esters have antiproliferative... | 05/15/2007 |
| 7217844 | Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid... | 05/15/2007 |
| 7193080 | Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound A dye-forming coupler and compound of formula (I): wherein Q represents a residue that forms, together with —N—C═N—, a nitrogen-containing 6-membered ring; RA represents an aryl, heterocyclic, ... | 03/20/2007 |
| 7182792 | Composition for dyeing keratinous fibers comprising at least one azodiazine direct dye and dyeing method using it The present invention relates to a composition for dyeing keratinous fibers, containing at least one azodiazine direct dye corresponding to the following formula (I): The present invention also relates to a method ... | 02/27/2007 |
| 7176310 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents This invention is directed to compound of the following formula (I): wherein R1, R2, R3 and R4 are as described herein. These compounds and pharmaceutical compositions ... | 02/13/2007 |
| 7175672 | Composition for dyeing keratinous fibers comprising at least one azodiazine direct dye aminated at the 7-position and process for dyeing The present disclosure relates to a composition for dyeing keratinous fibers, comprising at least one azodiazine direct dye aminated at the 7-position. The present disclosure also relates to a process for dyeing keratinous fibers using the direct dyes described here... | 02/13/2007 |
| 7115615 | Quinazoline derivatives The invention concerns quinazoline derivatives of Formula (I) wherein each of m, R1, n, R2 and R3 have any of the meanings defined in the description; processes for their preparat... | 10/03/2006 |
| RE39324 | Pyrimidine derivatives and oligonucleotides containing same Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides intermediates a... | 10/03/2006 |
| 7105663 | Derivatives of pyrimido[6,1-a]isoquinolin-4-one Compounds of general formula (I) wherein each of R1 and R2 independently represents a C1-6 alkyl or C2-7 acyl group; R5 represents a hydrogen atom or a C1-3 alkyl, C2-3 alkenyl or C2-3... | 09/12/2006 |
| 7091344 | Infrared chromophores An infrared dye, characterized in that the dye comprises of Formulae 1 to 5 ... | 08/15/2006 |
| 7078409 | Fused quinazoline derivatives useful as tyrosine kinase inhibitors The present invention is directed to a compound having the structure wherein A is a 7–18 membered ring that comprises 0 to 6 heteroatoms selected from O, S, and N; R1 is selected from the group consi... | 07/18/2006 |
| 7056937 | Sulfonylquinoxalone derivatives as bradykinin antagonists Disclosed are 1-sulfonylquioxalone acetamides and derivatives thereof. The compounds are exemplified by compounds of the formula: Such compounds, derivatives and related compounds are useful as bradykinin antagon... | 06/06/2006 |
| 7034153 | Tricyclic and heterocyclic derivative compounds and drugs containing these compounds as the active ingredient Tri-heterocyclic compound of formula (I) wherein each of W, X and Y is carbon or nitrogen; each of U and Z is CR2, NR13, nitrogen, oxygen, sulfur etc.; A ring is carbocyclic ring, heterocyclic ring... | 04/25/2006 |
| 7005440 | Therapeutic uses of tri-aryl acid derivatives The use of triaryl acid derivatives of formula (I) and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR ligand receptor binders of this invention are useful as agonists or antagonists of the P... | 02/28/2006 |
| 6951931 | Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides inte... | 10/04/2005 |
| 6951865 | Fused heterotricyclic compounds, process for preparing the compounds and drugs containing the same The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula, a pharmacologically acceptable salt thereof or hydrates thereof.... | 10/04/2005 |
| 6844340 | Tricyclic 2-pyrimidone compounds useful as HIV reverse transcriptase inhibitors The present invention relates to tricyclic 2-pyrimidone compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of H... | 01/18/2005 |
| 6800743 | Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides interm... | 10/05/2004 |
| 6794389 | Quinazoline derivatives and drugs There is provided an excellent novel analgesic having an analgesic effect which is effective widely against a pain including a chronic pain or an allodynia accompanied with herpes zoster by acting on a nociceptin receptor. The present invention relates to a c... | 09/21/2004 |
| 6743785 | Agents and methods for the treatment of proliferative diseases The present invention provides selective kinase inhibitors of formula (I). ... | 06/01/2004 |
| 6699861 | Anti-quinazoline compounds Dihydroquinazoline derivatives of the formula ##STR1## where R3 is --(CH2)p --A where p is from 1 to 4 and A is a 5- or 6-membered N-containing heterocyclic ring attached via the N atom or A is --NA'A" wherein A' and A" ar... | 03/02/2004 |
| 6562121 | Conditioning of organic pigments Organic pigments are conditioned by introducing a liquid prepigment suspension into a miniaturized continuous reactor and thermally treating therein.... | 05/13/2003 |
| 6525061 | Methods for the solid phase synthesis of 2-amino-4(H)-quinazolinone derivatives The present invention relates to solid phase synthesis of substituted 2-amino-4(H)-quinazolinone compounds of formula (I): ##STR1## having pharmacological activity, to processes for their preparation, to a combinatorial library and solid phase methods for... | 02/25/2003 |
| 6448254 | Substituted amides, their production and their use Amides of the general formula I ##STR1## and their tautomeric and isomeric forms, possible enantiomeric and diastereomeric forms, as well as possible physiologically tolerable salts, in which the variables have the following meanings: R1 [sic] can be C | 09/10/2002 |
| 6436925 | Substituted benzamides, their production and their use as cysteine protease inhibitors Benzamides of the formula I ##STR1## and its tautomeric forms, possible enantiomeric and diastereomeric forms, E and Z forms, and possible physiologically tolerated salts, in which the variables have the following meanings: R1 --C1 -... | 08/20/2002 |
| 6436949 | Heterocyclically substituted benzamides and their use Heterocyclically substituted benzamides of the formula I ##STR1## are described, where R1, R2, R3, R4, R5, X, m and n have the meanings given in the description. The novel compounds are useful for con... | 08/20/2002 |
