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| Number | Title | Issue Date |
| 7777032 | Quinazoline analogs as receptor tyrosine kinase inhibitors This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to three independent R... | 08/17/2010 |
| 7595400 | Process for the preparation of hexacyclic compounds This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically acceptable salts thereof. The compounds of the formula [1] are hexacycli... | 09/29/2009 |
| 7427693 | Polar liquid crystal Compounds that are useful in compositions for flat panel displays, for example, are provided. The compounds provided are polar, and are useful in low threshold voltage mixtures. The compounds provided have the general structure: CpCOCH2[A] | 09/23/2008 |
| 7420056 | Substituted bicyclic imidazo-3-ylamine compounds Substituted bicyclic imidazo-3-yl-amine compounds are provided, as well as processes for the production thereof and pharmaceutical formulations containing these compounds. The use of these compounds for the production of pharmaceutical formulations and related metho... | 09/02/2008 |
| 7393367 | Agent for dyeing keratin-based fibers An agent for dyeing keratin-containing fibers, especially human hair, is comprised of a cosmetic carrier, and (A) at least one compound of Formula I, wherei... | 07/01/2008 |
| 7390814 | Substituted hexahydropyrazino [1,2-a] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments Substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments The invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerat... | 06/24/2008 |
| 7321033 | 3-B-D-ribofuranosylthiazolo [4,5-] pyrimidine nucleosides and uses thereof The invention is directed to 3-β-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compou... | 01/22/2008 |
| 7307168 | Process for the preparation of 3-{2-′4- (6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyllethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido′1,2-methyl-4h-pyrido′,2-a!pyrimidin-4-one The invention relates to a process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl}-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one of the Formula (I), and pharmaceutically acceptable acid addition salts thereof by sub... | 12/11/2007 |
| 7291584 | Use of metal complex compounds as oxidation catalysts Use of metal complex compounds of formula (1) and/or (1′) [LnMemXp]zYq, (1) [L′nMemXp]zYq, (1′) wherein all su... | 11/06/2007 |
| 7268229 | Compounds to co-localize luminophores with luminescent proteins A method of measuring the enzymatic activity of a luciferase includes contacting a luminogenic protein, such as a luciferase, with a protected luminophore to form a composition; and detecting light produced from the composition. The protected luminophore provides in... | 09/11/2007 |
| 7238771 | Dibenzodiazocine polymers Dibenzodiazocine polymers, methods for producing dibenzodiazocine polymers, products formed from dibenzodiazocine polymers, and uses for such dibenzodiazocine polymers are provided. ... | 07/03/2007 |
| 7217717 | Phenalene derivatives Novel 1,3,4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives are disclosed. These compounds inhibit epidermal growth factor receptor (“EGFR”) tyrosine kinase. These compounds and their pharmaceutically acceptable salts and esters have antiproliferative... | 05/15/2007 |
| 7176310 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents This invention is directed to compound of the following formula (I): wherein R1, R2, R3 and R4 are as described herein. These compounds and pharmaceutical compositions ... | 02/13/2007 |
| 7160890 | Compounds specific to adenosine Areceptor and uses thereof This invention pertains to compounds which specifically inhibit the adenosine A3 receptor and the use of these compounds to treat a disease associated with A3 adenosine receptor in a subject, comprising administering to the subject a therapeuti... | 01/09/2007 |
| 7138363 | Use of metal complex compounds as oxidation catalysts Use of metal complex compounds of formula (1) and/or (1′) [LnMemXp]zYq (1), [L′MemXp]zYq (1′), wherein all substituents are as defined in the claims, as catalysts for oxidation reactions, and also novel metal complex compounds and novel ligands. ... | 11/21/2006 |
| 7119111 | 2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use Selected compounds are effective for treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and m... | 10/10/2006 |
| 7109195 | Hexacyclic compounds and their therapeutic use The present invention relates to hexacyclic compound of the formula [1], wherein Z, R3 and R4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are us... | 09/19/2006 |
| 7094783 | Bicyclic pyrimidinones as coagulation cascade inhibitors The present invention relates generally to compounds that inhibit serine proteases. In particular it is directed to novel amino-bicyclic pyrimidinone compounds of Formula (I): or a stereoisomer or pharmaceuticall... | 08/22/2006 |
| 7045624 | Compounds and their uses Use of a compound according to Formula [I]: or a salt thereof to produce a cooling sensation, wherein R1 and R2 are independently selected from hydrogen or halogen atoms; hydroxy, cyano, nit... | 05/16/2006 |
| 7037880 | Ethylene derivatives and pesticides containing said derivatives Ethylene derivatives of formula (I): where Q is an unsubstituted or substituted phenyl or heterocyclic group, especially a 4-thiazolyl, 1- or 3-pyrazolyl, 1,3-oxazol-4-yl, phenyl or pyridyl group; E is a substituent su... | 05/02/2006 |
| 7011701 | Dye and ink jet printing ink A dye is disclosed, which is represented by the following formula: wherein Z is an atomic group necessary to form a 6-membered nitrogen containing aromatic ring; R11 is a hydrogen bonding group; R12 | 03/14/2006 |
| 6962991 | Process for the synthesis of pyrazolopyrimidines The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a halogenated pyrazolopyrimidine base and removing the halogen after the base... | 11/08/2005 |
| 6951931 | Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides inte... | 10/04/2005 |
| 6916364 | Ink jet recording liquid An ink jet recording liquid including a compound represented by the following Formula (1), (2) or (3): ... | 07/12/2005 |
| 6846335 | Crystal form of a perinone dye A novel crystal form of C.I. Solvent Orange 60 gives a higher space-time yield in dye synthesis and is more easily finished. ... | 01/25/2005 |
| 6833455 | Bridged perinones/quinophthalones Disclosed herein are bridged perinones/quinophthalones of the general formula (I) or tautomeric forms thereof where X1, X2, Ar1 Ar2 and B are as described herein and are particularly characterized... | 12/21/2004 |
| 6831074 | Pharmaceutically active compounds The present invention provides a compound of formula (I): where Q is a group of formula: These compounds inhibit cyclic guanosine 3′,5′-monophosphate phosphodiesteras... | 12/14/2004 |
| 6825194 | Hexacyclic compounds The present invention relates to hexacyclic compound of the formula [1], wherein Z, R3 and R4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are useful i... | 11/30/2004 |
| 6821978 | Xanthine phosphodiesterase V inhibitors A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: | 11/23/2004 |
| 6800743 | Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides interm... | 10/05/2004 |
| 6703504 | Conformationally constrained compounds as dendrimer cores There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic polymers and oligomers, of a type having at least four poly... | 03/09/2004 |
| 6692562 | Process for making perylene pigment compositions This invention relates to a process of preparing a perylene pigment compositions containing a reactive co-precipitated blend of (1) about 75 to about 99.9 mol %, relative to the pigment composition, of a compound having the formula (I) ##STR1## w... | 02/17/2004 |
| 6683028 | Cyclic guanidine derivatives and their use as pesticides The invention relates to novel guanidine derivatives of the formula (I) ##STR1## in which A, R1, R2, R3 and Z are as defined in the description, to a process for their preparation and to their use for controlling animal ... | 01/27/2004 |
| 6562968 | Method of purifying tetrodotoxin The present invention relates to a new process of purifying tetrodotoxin using high performance liquid chromatograph technology.... | 05/13/2003 |
| 6491847 | Discotic liquid crystal and organic electroluminescence device using same A novel class of discotic liquid crystals represented by the following formula was synthesized, and a layer thereof was incorporated in an organic electroluminescence device. ##STR1##... | 12/10/2002 |
| 6491749 | Core-extended perylene bisimides The present inventions relates to nucleus-extended perylenebisimides of formula (I) ##STR1## intermediates in the preparation of compounds (I) and processes for the preparation of those intermediates and also processes for the preparation of compound... | 12/10/2002 |
| 6414127 | Pyrimidine derivatives for labeled binding partners Compounds having structure (1) ##STR1## wherein R1 is --H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides intermediates and methods make th... | 07/02/2002 |
| 6380193 | Fused tricyclic compounds, methods and compositions for inhibiting PARP activity A compound of formula I: ##STR1## or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof.... | 04/30/2002 |
| 6281355 | Nitrogen-containing tetracyclic compounds A nitrogen-containing tetracyclic compound represented by the formula: ##STR1## wherein Y1 --Y2 --Y3 is N--C.dbd.N or a group represented by the formula: C.dbd.C--NR3 (wherein R3 is a hydrogen atom, a ... | 08/28/2001 |
| 6255488 | Bicyclic amidines, process for their preparation, and their use as catalyst The process for the preparation of bicyclic amidines of the general formula: ##STR1## wherein A is selected from the group consisting of --CR1 R2 --CR3 R4 --CR5 R6 --, --CR1 R | 07/03/2001 |
