Bizarre Patents
A gun that fires a missile, powered by gas "discharged by the operator of the toy."
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7906644 | 2,4-pyrimidinediamine compounds and their uses The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a... | 03/15/2011 |
| 7767811 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 08/03/2010 |
| 7585974 | Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, their preparation and their therapeutic application Compounds complying with the general formula in which R either represents a halogen atom or a phenyl group substituted by one or more groups chosen from halogen atoms and (C1-C6)alkyl, (C1-C... | 09/08/2009 |
| 7517983 | Hydrazines and derivatives production process from hydrazines and dicarboxylic acid The present invention describes a process to form hydrazides from the reaction of a hydrazine and a dicarboxylic, using a Lewis acid as a main reagent of the reaction. The reaction occurs in a safe reactional environment, utilizing smooth conditions, neither involvi... | 04/14/2009 |
| 7320977 | Substituted 2-phenyl-3(2h)-pyridazinones The invention relates to substituted 2-Phenyl-3(2H)-Pyridazinones, to a method for the production thereof, and to their use as medicaments for the prophylaxis and/or treatment of diseases in humans and/or animals. ... | 01/22/2008 |
| 7214800 | Compounds, compositions, and methods Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed. ... | 05/08/2007 |
| 7205289 | Combinations of active ingredients with insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 04/17/2007 |
| 7148219 | Biaryl heterocyclic compounds and methods of making and using the same The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety th... | 12/12/2006 |
| 7115591 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2), COX-2 is the inducible isofo... | 10/03/2006 |
| 7012041 | Phenylpyridazinones The invention relates to novel phenylpyridazinones of the general formula (I) in which R1, R2, R3, R4, R5 and R6 are each as defined in the description, ... | 03/14/2006 |
| 7001895 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform ass... | 02/21/2006 |
| 6982331 | Synthesis of chlorinated pyrimidines The invention provides a process for synthesizing chlorinated pyrimidines. The process includes reacting imidoyl chloride compounds with phosgene (COCl2). The imidoyl chloride compounds can be supplied as starting materials or can be produced by reacting ... | 01/03/2006 |
| 6962905 | Pharmaceutical formulation comprising a low molecular weight thrombin inhibitor and its prodrug A kit of parts containing (a) a pharmaceutical formulation including a low molecular weight thrombin inhibitor, or a pharmaceutically acceptable derivative thereof, in admixture with a pharmaceutically acceptable adjuvant, diluent or carrier, and (b) a pharmaceutica... | 11/08/2005 |
| 6919323 | Pyridazinone inhibitors of fatty acid binding protein and method aP2 inhibiting compounds are provided having the formula wherein A, X, R and Z are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employi... | 07/19/2005 |
| 6894005 | Herbicides Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomer of those compounds, are suitable for use as herbicides. ... | 05/17/2005 |
| 6878709 | 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists Disclosed are compounds of the formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory diso... | 04/12/2005 |
| 6828276 | Herbicidally active benzoylcyclohexanediones There are described benzoylcyclohexanediones of the formula I, their preparation, and their use as herbicides and plant growth regulators. In this formula (I), C1, C2, C3 are cyclic radic... | 12/07/2004 |
| 6777412 | Fungicides The invention provides fungicidal compounds of formula (I) or stereoisomers thereof: wherein X is CH2O; A is hydrogen; E is hydrogen; q is 1; any two of K, L and M are nitrogen and the other is CH; T is oxygen... | 08/17/2004 |
| 6730674 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors This invention relates to novel sulfonyl pyridazinone compounds of the formula: wherein R1, R2, X, and Y are defined herein, which are useful as aldose reductase inhibitors in the treatment or preve... | 05/04/2004 |
| 6653321 | Naphthylsulfonic acids and related compounds as glucose uptake agonists Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptabl... | 11/25/2003 |
| 6551963 | Phenylpyridazinones The invention relates to novel phenylpyridazinones of the general formula (I) ##STR1## in which R1, R2, R3, R4, R5 and R6 are each as defined in the description, to processes for their prep... | 04/22/2003 |
| 6525053 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors The present invention describes pyridazione compounds having the formula (I), which are cyclooxygenase (COX) inhibitors The compounds are selective inhibitors of cyclooxygenase-2-(COX-2), which is the inducible isoform associated with inflammation, as opp... | 02/25/2003 |
| 6469003 | Pyridazinone derivatives A pyridazinone derivative represented by formula (I): ##STR1## a pharmaceutically acceptable salt thereof, or a derivative thereof, or a pharmaceutical composition comprising as an active ingredient the derivative or a pharmaceutically acceptable salt the... | 10/22/2002 |
| 6362193 | Cycloalkenyl substituted compounds Novel pyridyl or pyrimidinyl substituted cycloalkenyl compounds and compositions for use in therapy.... | 03/26/2002 |
| 6307047 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors The present invention describes pyridazinone compounds of formula I ##STR1## which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, a... | 10/23/2001 |
| 6271373 | Compounds, compositions and methods for treating influenza A compound produced by the process comprising the step of reacting a starting compound of the formula: ##STR1## with FeCl3 in the presence of acetic acid, wherein the reaction mixture is heated and the temperature of the reaction mixture is abo... | 08/07/2001 |
| 6225313 | Substituted 2-phenyl-3(2H)-pyridazinones Substituted 2-phenyl-3(2H)-pyridazinones I ##STR1## and salts thereof, where n=0, 1, 2; R1 =C1 -C4 -alkyl, C1 -C4 -haloalkyl; R2 =H, halogen; R3 =halogen, CN; R4 =H, NO2 | 05/01/2001 |
| 6214857 | Substituted alkanohydroxamic acids and method of reducing TNF levels Imido and amido substituted alkanohydroxamic acids reduce the levels of TNF and inhibit phosphodiesterase in a mammal. A typical embodiment is 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide.... | 04/10/2001 |
| 6194575 | Method for producing 1,3-di-substituted 2-nitroguanidines The present invention relates to a process for the preparation of compounds of the formula (I) ##STR1## by reacting compounds of the formula (II) ##STR2## in which Het, R1, R2 and R4 are as defined in the description, with... | 02/27/2001 |
| 6121251 | Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides Compounds with fungicidal and insecticidal properties having formula I ##STR1## wherein W is ##STR2## n is 0 or 1; Y is O, S, NR1, or R6 ; the ring bond containing R4 and R5 is a single or double bond; X is... | 09/19/2000 |
| 6114524 | Process for producing halogenated heteroaryl compounds The present invention relates to a process for producing a compound represented by the formula (II): ##STR1## wherein X is a halogen atom, each of A1, A2 and A3 are the same or different and are selected from a carbon... | 09/05/2000 |
| 6046203 | Substituted 3-(aminoalklamino)-1,2-benzisoxazoles and related compounds This application relates to compounds of the formula ##STR1## wherein R1,X, Y and n are as defined in the specification; and pharmaceutically acceptable addition salts thereof and optical and geometric isomers or racemic mixtures thereof; ... | 04/04/2000 |
| 6004933 | Cysteine protease inhibitors The present invention relates to cysteine protease inhibitors of the general formula (I): ##STR1## wherein Z is a cysteine protease binding moiety; X and Y are S, O or optionally substituted N; and R1 is optionally substituted alkyl or ... | 12/21/1999 |
| 6004960 | Pyridazinones as inhibitors of cyclooxygenase-2 The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of ... | 12/21/1999 |
| 5994353 | Aromatic compounds and pharmaceutical compositions containing them The invention relates to compounds of formula I and pharmaceutically acceptable salts and in vivo hydrolysable esters and amides thereof and processes for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them. ... | 11/30/1999 |
| 5965732 | Sulfonamide endothelin antagonists Compounds of the formula ##STR1## inhibit endothelin, wherein: R is phenyl, naphthyl or biphenyl, each of which may be substituted.... | 10/12/1999 |
| 5942511 | Allylthiopyridazine derivatives and process for preparing the same The, present invention relates to a novel allylthiopyridazine derivative represented by formula (I) which exhibits a superior effect for prevention and treatment or hepatic diseases induced by toxic substances and for protection of human tissues from radi... | 08/24/1999 |
| 5859008 | Arylalkyl diazinones Arylalkyl diazinone derivatives of the formula I ##STR1## and their physiologically acceptable salts, in which R1, R2, R3, R4, B, Q and X have the meanings indicated in claim 1, exhibit phosphodiesterase IV inhi... | 01/12/1999 |
| 5821243 | Compounds compositions and methods for treating influenza A compound of the formula: ##STR1## wherein R1 represents a lower alkyl (C1 --C6) substituent which may be straight or branched; R2 represents an aryl substituent of the formula: ##STR2## and Q, V... | 10/13/1998 |
| 5795892 | 4-aminopyridazines, method of preparing them and drugs containing these compounds The invention concerns new 4-aminopyridazines of the general formula I ##STR1## in which R1 denotes an R2 --SO2 --O-- or R2 --SO2 --NR3 -- group in which R2 denotes a cycloalkyl ... | 08/18/1998 |
