Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 8350025 | Process for preparing 6-phenoxypyrimidin-4-OL derivatives in the presence of a quinuclidine or a -methyl pyrrolidine derivatives The present invention relates, inter alia, to a process for preparing a compound of formula (I): using a quinuclidine-based catalyst or an optionally 3-substituted N-methyl pryrrolidine-based catalyst. ... | 01/08/2013 |
| 7829701 | Process for continuous production of the salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2,-dioxide The invention discloses a kind of sulfonation cyclization technique for synthesizing acesulfame potassium for continuous production without stirring and special equipment for this technique. An injection pump is adopted to directly inject the sulfonation raw materia... | 11/09/2010 |
| 7662957 | Method for producing 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or salt thereof A high quality 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or a salt thereof is obtained easily and efficiently. When the compound represented by the following formula (2) [Formula 2] (wherein, R | 02/16/2010 |
| 7408059 | Method for producing 3, 4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or salt thereof A method produces a 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound of following formula (2): wherein R1 and R2 are the same as or different from each other and are each hydrogen atom or an org... | 08/05/2008 |
| 7301028 | Mitotic kinesin inhibitors The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which com... | 11/27/2007 |
| 7294650 | Benzothiophen and thiochrone containing phenethanolamine derivatives for the treatment of respiratory disorders Compounds of formula (I): and salts, solvates, and physiologically functional derivatives thereof, useful for the prophylaxis or treatment of a clinical condition for which a selective β2-adrenorecept... | 11/13/2007 |
| 7259258 | Methods of attaching biological compounds to solid supports using triazine Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to the triazine moiety. ... | 08/21/2007 |
| 7196108 | Bicyclic heterocycles for the treatment of diabetes and other diseases The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, and atherosclerosis. | 03/27/2007 |
| 7141562 | Substituted benzoxazinones and uses thereof Compound of the Formula: and pharmaceutically acceptable salts or prodrugs thereof, wherein: X is CH or N, Y is C or S, Z is —SO2— or —(CRaRb)r—, n is 1 or 2, R... | 11/28/2006 |
| 7105660 | Intramolecular amidation of sulfamates catalyzed by metalloporphyrins An intramolecular amidation processes for substrates such as sulfamates using chiral and non-chiral metalloporphyrin complexes which can maximize catalytic activity, enhance efficiency, stereoselectivity and speed of amidation reactions is described. The chiral meta... | 09/12/2006 |
| 7053109 | Aminediols for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the... | 05/30/2006 |
| 6960669 | Utilization of phosphorus pentasulfide in thionylations using phase transfer catalysis A method is disclosed for the preparation of benzo[b]thiophenecarbodithioic esters of the formula: wherein R is alkyl, R1 is hydrogen, halogen, or alkyl, R2, R3, R4, and R | 11/01/2005 |
| 6867298 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 03/15/2005 |
| 6852885 | Production method of high purity organic compound There is provided a method for obtaining a target organic compound such as an alkyladamantyl ester efficiently by purifying a crude organic compound which contains, as impurities, sublimable materials which start to sublime at temperatures lower than a boiling point... | 02/08/2005 |
| 6849623 | Xanthine and phenazone-acesulfame-H complexes having improved taste, process for their preparation and their use Complex compounds or adducts of xanthine derivatives, for example propentofylline or pentoxyfylline, or phenazone derivatives, for example phenazone, propylphenazone and aminophenazone, and acesulfame-H, in which the components are present in a molar ratio of 1:1 or... | 02/01/2005 |
| 6797522 | Synthetic receptors The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and may independently be straight chain, cyclic or branched. The template... | 09/28/2004 |
| 6759544 | Antimicrobially active acesulfame complexes, process for their preparation and their use Complex compounds containing acesulfame have good antimicrobial action, in particular antibacterial action, and are distinguished by the fact that they are complex compounds of metallic elements such as zinc, copper, silver, or nonmetallic quaternary ammonium cation... | 07/06/2004 |
| 6734304 | Method for producing asymmetrical 4,6-bis(aryloxy)pyrimidine derivatives The invention relates to a novel process for preparing known asymmetrical 4,6-bis(aryloxy)pyrimidine derivatives. ... | 05/11/2004 |
| 6727359 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor Acesulfame-K is a widely used sweetener in food and beverage. It is prepared by using the substituted sodium phenoxide or substituted phenol as the starting substance to synthesize the following three intermediates: a substituted phenoxide sulfonylchloride(I), a sub... | 04/27/2004 |
| 6562811 | Pyridine derivatives Pyridine compounds of general formula: ##STR1## wherein --R1 represents ##STR2## in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 | 05/13/2003 |
| 6528648 | Detecting reagent for double-stranded nucleic acid and double-stranded nucleic acid detecting method The present invention provides a novel detecting reagent for double-stranded nucleic acid, and a method of using it to detect double-stranded nucleic acid formed by hybridization with a probe, with absolutely no labeling of the target nucleic acid. The de... | 03/04/2003 |
| 6436927 | IL-8 receptor antagonists The present invention involves certain 8-ureido and 8-thioureido, 1,2-benzothiazines, 1,2,4-benzothioxazines and 1,2,4-benzothiodiazines useful in the treatment of disease states mediated by the chemokine, Interleukin-8.... | 08/20/2002 |
| 6407097 | Methoximinomethyloxathiazines The invention relates to novel methoximinomethyloxathiazines, to two processes for their preparation and to their use as pesticides.... | 06/18/2002 |
| 6271235 | HIV protease inhibitors HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain the... | 08/07/2001 |
| 6268311 | 1-Amino-3-benzyluracils 1-Amino-3-benzyluracils I ##STR1## (X=oxygen, sulfur; R1 =C1 -C4 -haloalkyl; R2 =H, halogen; R3, R7 =H, CN, SCN, halogen, C1 -C4 -haloalkyl, C1 -C4 -h... | 07/31/2001 |
| 6265398 | Substituted pyridines/pyrimidines, their preparation and their use as pesticides The present invention relates to novel substituted pyridines/pyrimidines of the formula I ##STR1## where A is CH or N; X is NH, O or S(O)q where q is 0, 1 or 2; Y1, Y2 and Y3 independently of one another are a group ... | 07/24/2001 |
| 6245934 | Method for preparing salts of aspartame from N-protected aspartame Method for preparing a salt of aspartylphenylalanine methyl ester from N-protected aspartylphenylalanine methyl ester involving cleaving off the protective group by treatment with an acid, in the course of which, first of all, N-protected aspartylphenylal... | 06/12/2001 |
| 6063917 | Cephalosporin synthesis A process for the production of a compound of formula ##STR1## wherein Ra denotes hydrogen or silyl; Rb denotes a group of formula --ORe, wherein Re denotes hydrogen or alkyl; and Rc and Rd toge... | 05/16/2000 |
| 6020335 | (N-(pyridinylmethyl)-heterocyclic)ylideneamine compounds as nicotinic acetylcholine receptor binding agents An (N-(pyridinylmethyl)-heterocyclic)ylideneamine compound of the formula ##STR1## wherein R3, A, and B are as described below, and its pharmaceutically acceptable salts and prodrugs. Compounds of the formula I and their pharmaceutically a... | 02/01/2000 |
| 5962437 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus and herpes viruses, is disclosed. The method comprising administering to a subject in need of such treatment an infection-combating amount of a phospholipid or phospholipid ... | 10/05/1999 |
| 5922113 | Antibacterial and antifouling oxathiazines and their oxides Use of 3-aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides having the formula ##STR1## wherein n is 0, 1 or 2; R1 is hydrogen, C1-4 alkyl or benzyl; and R represents (a) phenyl; phenyl substituted with 1 to 3 substituents ... | 07/13/1999 |
| 5914351 | Anti-viral aromatic hydrazones Compounds of the formula ##STR1## wherein Q is a hydrazone derivative; R1 is hydrogen, halogen, alkyl or alkoxy; R2 is hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkynyloxy, halomethyl, trifluoromethoxy, alkylthio, nitro or cyano; a... | 06/22/1999 |
| 5874382 | Cyclic sulfonamide herbicides Compounds of Formula I and II, and their agriculturally-suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## wherein X is a direct bond; O; S; NH; N(C1 -C3 alkyl); N(C1 -C3... | 02/23/1999 |
| 5824677 | Substituted amino alcohol compounds Disclosed are compounds having a straight or branched aliphatic hydrocarbon structure of formula I: ##STR1## In formula I, n is an integer from one to four and m is an integer from four to twenty. Independently, R1 and R2 are hy... | 10/20/1998 |
| 5780465 | 4-substituted 5-polycyclylpyrimidine herbicides 4-Substituted 5-polycyclylpyrimidine compounds in which the 5-substituent is polycyclic and is attached to the pyrimidine moiety through an aliphatic carbon atom, such as 5-(2,2-dimethylindan-1-yl)-4-methylthiopyrimidine, were prepared and found to p... | 07/14/1998 |
| 5777110 | Wood preservative oxathiazines The present invention provides certain 3-aryl-5,6-dihydro-1,4,2-ocathiazines and their oxides, useful for the long-term preservation of wood and composite wood materials against wood damaging and wood destroying materials. The present invention also ... | 07/07/1998 |
| 5744010 | Process for the preparation of the non-toxic salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and arrangement for carrying out this process The invention relates to a process for the preparation of acesulfam salts by reaction of salts of amidosulfonic acid with diketene to give a salt of acetoacetamidosulfonic acid (I), ring closure by the action of at least about an equivalent amount of SO | 04/28/1998 |
| 5696154 | Brefeldin A derivatives and their utility in the treatment of cancer Provided are brefeldin A derivatives of the formula: ##STR1## wherein one of R1 and R2 is H and the other of R1 and R2 is a substituent group having 1 to 12 carbon atoms containing a basic nitrogen atom or ... | 12/09/1997 |
| 5688809 | 5-heteroarylindole derivatives The present invention relates to compounds of the formula ##STR1## The present invention also relates to intermediates for the preparation of compounds of the formula I, pharmaceutical compositions and method of use.... | 11/18/1997 |
| 5641783 | Substituted amino alcohol compounds Disclosed are compounds having a straight or branched aliphatic hydrocarbon structure of formula I: ##STR1## In formula I, n is an integer from one to four and m is an integer from four to twenty. Independently, R1 and R2 are hy... | 06/24/1997 |
