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Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 7427618 | Ethynyl derivatives as factor Xa inhibitors Novel compounds of the formula (I), in which R1, R2, R3, X and Y have the meaning indicated in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic di... | 09/23/2008 |
| 7268124 | Geranylgeranyl pyrophosphate synthase inhibitors The invention provides novel pyrophosphate synthase inhibitors of formula I as well as compositions comprising such inhibitors and methods for their use. ... | 09/11/2007 |
| 7077976 | Phosphonamide and phosphonamide blend compositions to treat water The invention is a water treatment composition comprising at least one phosphonamide and blends thereof and a method to treat water. As phosphonamides are generally odorless, and typically solids, phosphonamide and phosphonamide blend compositions are generally odor... | 07/18/2006 |
| 6800659 | Compounds for modulating cell proliferation Novel styrylacrylonitrile compounds which are useful in treating a variety of cell proliferative disorders such as cancer are disclosed. The compounds are of the Formula I: ... | 10/05/2004 |
| 6743798 | Substituted pyrazole derivatives condensed with six-membered heterocyclic rings The present invention relates to novel substituted pyrazole derivatives of the general formula (I) in which R1, R2, R3 and A are each as defined, and to processes for their preparation an... | 06/01/2004 |
| 6737416 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B A compound represented by the following general formula (I) and a pharmacologically acceptable salt thereof: wherein R1 represents hydrogen atom, an alkyl group, a substituted alkyl group and the like; R2... | 05/18/2004 |
| 6576161 | Polyphosphate ester morpholides, mixtures thereof, and thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants The present invention relates to polyphosphate ester morpholides, compositions comprising mixtures thereof and thermoplastic resin compositions containing the polyphosphate ester morpholide composition as a flame retardant. The flame retardant composition... | 06/10/2003 |
| 6235220 | Composition for producing a conductive composite material containing a polyaniline, and resulting composite material The invention concerns compositions for manufacturing composite materials containing a polyaniline. These compositions are formed by a solution in a solvent such as m-cresol of the following constituents: a) a conductive polyaniline protonated by means of a pr... | 05/22/2001 |
| 5962437 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus and herpes viruses, is disclosed. The method comprising administering to a subject in need of such treatment an infection-combating amount of a phospholipid or phospholipid ... | 10/05/1999 |
| 5962440 | Cyclic phosphonate ester inhibitors of microsomal triglyceride transfer protein and method Novel cyclic phosphonate ester inhibitors of MTP are provided which have the structure ##STR1## wherein R2, L2, A, B, L1, R1 and R5a are as set out herein. These compounds are useful in lowering ... | 10/05/1999 |
| 5932733 | 3-amino-2-oxo-1-piperidineacetic derivatives containing an arginine mimic as enzyme inhibitors The present invention discloses peptide aldehydes having a lactam group as part of the peptide backbone and having an original mimic group such as an amidinopiperidine or amidinophengyl tail. These compounds are potent and specific inhibitors of thrombin,... | 08/03/1999 |
| 5929236 | 2-substituted morpholine and thiomorpholine derivatives as GABA-B antagonists Disclosed are compounds of the formula I wherein: Y represents --CO2 H, --CO2 R6, --C(O)NHR7, --SO2 H, --SO3 H, --SO3 R6, --SO2 NHR7, --C(O)--N(OH)--R... | 07/27/1999 |
| 5914351 | Anti-viral aromatic hydrazones Compounds of the formula ##STR1## wherein Q is a hydrazone derivative; R1 is hydrogen, halogen, alkyl or alkoxy; R2 is hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkynyloxy, halomethyl, trifluoromethoxy, alkylthio, nitro or cyano; a... | 06/22/1999 |
| 5639732 | Phosphorous-containing cysteine and serine protease inhibitors The present invention is directed to novel phosphorous-containing inhibitors of cysteine or serine proteases. Methods for the use of the protease inhibitors are also described.... | 06/17/1997 |
| 5627173 | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Compounds of the formula I ##STR1## are suitable for producing pharmaceuticals for the treatment and prophylaxis of degenerative joint disorders, of rheumatic di... | 05/06/1997 |
| 5532226 | Trifluoromethybenzylphosphonates useful in treating osteoporosis Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone formation and bone mass.... | 07/02/1996 |
| 5457094 | Heterocyclic amidines useful for treating diseases associated with calcium metabolism Compounds of formula I ##STR1## wherein R, R1, R2 and q are as defined in the description, have valuable pharmacological properties and are especially effective as calcium metabolism regulators. They are prepared in a manner kno... | 10/10/1995 |
| 5442101 | Methylenebisphosphonic acid derivatives The invention relates to novel methylenebisphosphonic acid ester amide derivatives of general formula (I), in which formula W1, W2, W3 and W4 are independently the group OR1 or the group NR2 | 08/15/1995 |
| 5403932 | Phosphoramidates useful as antitumor agents Compounds of the formula: ##STR1## which is further defined herein, possess anti-tumor activity.... | 04/04/1995 |
| 5360563 | Trisamidodithionodiphospates There are disclosed compounds of formulae I and Ia ##STR1## wherein R1 and R2 are each independently of the other C1 -C13 alkyl which may be interrupted by oxygen, C5 -C6 cycloalkyl or... | 11/01/1994 |
| 5332845 | Phosphorylating reagents Novel phosphorylating reagents are provided which are useful in DNA synthesis and purification procedures. The reagents are substituted phosphines which are particularly useful in the phosphorylation of nucleoside and solid supported oligonucleotides at t... | 07/26/1994 |
| 5304549 | Amino acid derivatives Compounds of the formula ##STR1## wherein A is the group ##STR2## R1 is hydrogen, amino, protected amino, acylamino or lower alkyl optionally substituted by aryl, hydroxy, protected hydroxy, amino, protected amino, acylamino, mal... | 04/19/1994 |
| 5300687 | Trifluoromethylbenzylphosphonates useful in treating osteoporosis Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone formation and bone mass.... | 04/05/1994 |
| 5250522 | Phosphono/biaryl substituted amino acid derivatives The present invention relates to the N-phosphonomethyl-biaryl substituted amino acid derivatives of formula I ##STR1## wherein X represents a direct bond, C1-4 -alkylene or C2 -C4 -alkenylene; R and R' represent indep... | 10/05/1993 |
| 5217958 | 1,2-hydroxy phosphonates and derivatives thereof Compounds of the formula ##STR1## are disclosed. These compounds are inhibitors of renin and therefore useful as cardiovascular agents.... | 06/08/1993 |
| 5212304 | Amino-derivatized phosphoramidite linking agents The compounds of the invention include novel linking agents comprising 2-substituted-3-protected-1,3,2-oxazaphosphacycloalkanes and their phosphoramidite precursors. The compounds of the invention further include conjugates of the above linking agents wit... | 05/18/1993 |
| 5186733 | Arylphosphonodiamide compounds and herbicidal compositions thereof Herbicides have the formula ##STR1## in which R is hydrogen, mono- or poly-halo, mono- or di-(C1 -C4 alkyl), C1 -C4 alkoxy, C1 -C4 haloalkoxy, phenoxy or nitro; R1 is hydrog... | 02/16/1993 |
| 5185334 | 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use Novel 2,2-disubstituted glycerol-like compounds are disclosed for use as anti-allergic and anti-inflammatory compounds. The compounds are antagonists of platelet activating factor ("PAF"). Also disclosed are methods of synthesizing and using the compounds... | 02/09/1993 |
| 5183811 | Glycerol derivative and anti-hypertensive agent A novel glycerol derivative which is effective to reduce blood pressure has the formula: ##STR1## wherein R1 is an alkyl group having 10-22 carbon atoms, R2 is lower acyl, benzoyl, aryl, mono-, di- or triarylalkyl, alkyl, cycloa... | 02/02/1993 |
| 5177095 | Triazole angiotensin II antagonists incorporating a substituted benzyl element Substituted triazoles attached through a methylene bridge to novel substituted phenyl derivatives of the Formula I, are useful as angiotensin II antagonists. ##STR1##... | 01/05/1993 |
| 5174913 | Polybasic acid esters as oil field corrosion inhibitors A corrosion inhibitor with excellent film forming and film persistency characteristics may be produced by first reacting in a condensation reaction a polybasic acid with a polyalcohol to form a partial ester. The partial ester is reacted with imidazoline ... | 12/29/1992 |
| 5155100 | Phosphono/biaryl substituted dipeptide derivatives The invention relates to the N-phosphonomethyl-biaryl substituted dipeptide derivatives of formula I ##STR1## wherein A represents a direct bond, lower alkylene, phenylene or cyclohexylene; m represents 1 or zero, provided that m represents 1 when A ... | 10/13/1992 |
| 5110347 | Substituted fused heterocyclic herbicides The invention relates to certain substituted fused compounds of Formula I ##STR1## which are useful as herbicides, and their agriculturally suitable compositions, as well as methods for their use as general or selective preemergent or postemergent he... | 05/05/1992 |
| 5103007 | Lipids Lipid derivatives represented by the formula: ##STR1## wherein R1 stands for an optionally substituted higher alkyl group, R2 stands for an optionally substituted lower alkyl group or an optionally substituted nitrogen-containin... | 04/07/1992 |
| 5091526 | Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines Biologically active, enantiomerically substantially pure intermediates of trans-hexahydro-benzo[d]naphtho[2,1-b]azepines are prepared. The present invention involves a process for preparing compounds of the general formula 3: ##STR1## wherein: R* is ... | 02/25/1992 |
| 5081245 | Carboxylic acid derivatives A compound represented by the formula: ##STR1## wherein R represents a hydrogen atom or a lower alkyl group; R1 represents a higher alkyl group which may be substituted; R2 represents a hydrogen atom or a lower alkyl group, a lower alkano... | 01/14/1992 |
| 5036152 | Alkoxycarbonylalkylphospholipids and alkylaminocarbonylalkylphospholipids Novel alkoxycarbonylalkylphospholipids, alkylaminocarbonylalkylphospholipids, processes for the preparation thereof, and methods for treating inflammation utilizing compounds or compositions thereof are disclosed.... | 07/30/1991 |
| 5030733 | Hydroxy-, alkoxy- and benzyloxy-substituted phospholipids Novel hydroxy-, alkoxy- and benzyloxy-substituted phospholipids, a process for the preparation thereof, and methods for treating pain, phospholipase, A2 mediated inflammation and similar conditions utilizing compounds or compositions thereof ar... | 07/09/1991 |
| 4992549 | Herbicidal compositions Aminotriazines of the formula ##STR1## wherein E is nitrogen, Z is oxygen or sulfur, R3 is hydrogen, C1 -C4 -alkyl, C3 -C4 -alkenyl or C1 -C4 -alkoxy, R4 is hydrogen, ... | 02/12/1991 |
| 4956467 | Nucleophilic tertiary organophosphines Novel nucleophilic tertiary organophosphines and the specific cleavage of peptide bonds by nucleophilic tertiary organophosphines. This invention is of particular utility in providing chemical agents for use in the cleavage of proteins and the determinati... | 09/11/1990 |
